MALDI imaging mass spectrometry differentiates basal cell carcinoma from trichoblastoma and trichoepithelioma: A proof of principle study. by Jennifer M C Ranes, Jessica L Moore, Nathan H Patterson, Sarah P Nicholson, Sara Kantrow, Jason Robbins, Richard M Caprioloi, Jeremy L Norris, Rami N Al-Rohil

“…While our findings are not yet validated for clinical use, this merits further research to support IMS as an ancillary diagnostic tool for adequately and efficiently identifying the most common cutaneous malignancy in the United States. …”
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Integration of multimodal imaging data with machine learning for improved diagnosis and prognosis in neuroimaging by Saurabh Bhattacharya, Sashikanta Prusty, Sanjay P. Pande, Monali Gulhane, Santosh H. Lavate, Nitin Rakesh, Saravanan Veerasamy

“…This work introduces a novel hybrid deep learning method combining CNN, GRU, and a Dynamic Cross-Modality Attention Module to help more efficiently blend spatial and temporal brain data. Through working around issues with current multimodal fusion techniques, our approach increases the accuracy and readability of diagnoses.MethodsUtilizing CNNs and models of temporal dynamics from fMRI connection measures utilizing GRUs, the proposed approach extracts spatial characteristics from sMRI. …”
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Development and evaluation of folic acid conjugated curcumin-loaded functionalized multiwalled carbon nanotubes for enhanced efficacy in ovarian cancer treatment by Aditi Chattaraj, Yachana Mishra, Alaa A.A. Aljabali, Vijay Mishra

“…Our research opens the door for the development of more individualized and effective alternative treatments for OC patients by more efficiently and specifically delivering curcumin to OC cells.…”
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Orbital Decay of the Ultra-hot Jupiter TOI-2109b: Tidal Constraints and Transit-timing Analysis by Jaime A. Alvarado-Montes, Mario Sucerquia, Jorge I. Zuluaga, Christian Schwab

“…This process depends on how efficiently the star and the planet dissipate energy, due mainly to interior mechanisms that are poorly constrained in exoplanet systems. …”
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Comparing the efficacy of hyaluronic acid products with various molecular weights as mono and combined with chondroitin sulfate regimens in treatment of patients with stage I–III k... by V. E. Bialik, M. A. Makarov, E. I. Bialik, S. A. Makarov, V. A. Nesterenko, M. R. Nurmukhametov

“…At stage II of the knee OA after 3 months after the course of IA HA, different efficiencies of HA preparations were revealed. …”
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Combined exercise training and dietary interventions versus independent effect of exercise on ectopic fat in individuals with overweight and obesity: a systematic review, meta‐anal... by Fatemeh Kazeminasab, Motahareh Mohebinejad, Mohammad Hossein Mahboobi, Maedeh Nojoumi, Saba Belyani, Reza Bagheri, Fred Dutheil

“…Additional investigation is required to delve into the processes behind these findings and to pinpoint treatments that efficiently focus on reducing ectopic fat.…”
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Optimizing the utilization of Metakaolin in pre-cured geopolymer concrete using ensemble and symbolic regressions by Kennedy C. Onyelowe, Viroon Kamchoom, Ahmed M. Ebid, Shadi Hanandeh, José Luis Llamuca Llamuca, Fabián Patricio Londo Yachambay, José Luis Allauca Palta, M. Vishnupriyan, Siva Avudaiappan

“…The integration of ensemble and symbolic regression models enables researchers to derive valuable predictions and optimize critical performance parameters efficiently. In this research work, 235 records were collected from extensive literature search for compressive strength for different mixing ratios of pre-cured metakaolin-based geopolymer concrete with concrete at different ages. …”
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Inhibition of SOD1 trimerization is a novel drug target for ALS disease by Tae-Gyun Woo, Jin Han, Yuju Kim, Young jun Hwang, Mua Lee, So-mi Kang, Soyoung Park, Yeongseon Ji, Yeon-Ho Chung, Songyoung Baek, Eunbyeol Shin, Minju-Kim, Hyewon Jang, Yun-Jeong Shin, Yonghoon Kwon, Bae-Hoon Kim, Bum-Joon Park

“…In vitro, PRG-A-04 selectively bound to the mutant form of SOD1, but not the wild type, and efficiently inhibited the aggregation caused by SOD1-G147P (a SOD1 trimer stabilizer). …”
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Comprehensive analysis of single-cell and bulk RNA sequencing data unveils antigen-presenting and processing fibroblasts and establishes a predictive model in gastric cancer by Chenggang Zhang, Fangqi Chen, Jie Li, Yixuan He, Juan Sun, Zicheng Zheng, Guanmo Liu, Yihua Wang, Weiming Kang, Xin Ye

“…A nomogram that efficiently predicted the overall survival of GC patients was established by integrating the risk score with age, T stage, N stage, and M stage. …”
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Inhibition Mechanism of Pleurotus citrinipileatus Sing. Ergothioneine on Pancreatic Lipase Activity by Zhangchen XIA, Xiaohui MENG, Ru FANG, Yanqing MAO, Junwen CHENG, Yanbin WANG, Juan XU, Liang HE

“…Fluorescence spectra data revealed PCEGT could efficiently static-quench the intrinsic fluorescence of PL by changing its space structure. …”
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Antibiotics in water: Bean pods as adsorbent for removing and recovering ciprofloxacin by Jennifer Gubitosa, Domenico Cignolo, Vito Rizzi, Luca Pace, Paola Fini, Andrea Petrella, Chiara Milanese, Sara Paraboschi, Pinalysa Cosma

“…Moreover, the roles of the physical and chemical parameters such as ionic strength, pH, adsorbent/pollutant amounts, and temperature, during the adsorption, were assessed, obtaining interesting information on the whole process, that occurred efficiently with a maximum adsorption capacity of 45 mg/g. …”
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Real-time augmented feedback for gait training: are gait responses affected by the choice of target parameter? by Mathilde Legrand, Mathilde Legrand, Mathilde Legrand, Florette Grenet, Olivia Hochstrasser, Olivia Hochstrasser, Andreas Luft, Andreas Luft, Roger Gassert, Roger Gassert, Roger Gassert, Olivier Lambercy, Olivier Lambercy, Chris Easthope Awai

“…However, we still lack crucial knowledge about how to most efficiently use it.Research QuestionHow does the selection of the gait parameter targeted by the AVF signal influence the global motor response (i.e., overall gait pattern)?…”
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Mesenchymal stem cell-derived extracellular vesicles attenuate periductal fibrosis by inhibiting Th17 differentiation in human liver multilineage organoids and Mdr2−/− mice by Wenyi Chen, Xinyi Chen, Feiqiong Gao, Qigu Yao, Sheng Cheng, Qiaoling Pan, Jiong Yu, Jinfeng Yang, Guanghua Ma, Jintao Gong, Qian Li, Yunhua Chen, Lee Wei Lim, Ilia Stambler, Georgina M. Ellison-Hughes, Brun Ulfhake, Robert Chunhua Zhao, Hongcui Cao

“…Moreover, miR-7977-enriched EVMSC efficiently reduces IL-17A+ cell percentages in fibrotic areas and improves periductal fibrosis in Mdr2−/− mice. …”
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Aircraft Multi-stage Altitude Prediction Under Satellite Signal Loss by Mengchan HUANG, Qiang MIAO

“…Addressing the longitudinal nature of aircraft flight parameter time series, a long temporal correlation attention (LTCA) mechanism is designed for feature extraction, enhancing spatiotemporal correlation representation. LTCA efficiently exploited attention mechanisms to extract key features from multi-dimensional flight parameter data samples through adaptive global average pooling (GAP) and one-dimensional convolution, considering global and local information. …”
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Prediction of slaughter weight with body components and liner body measurement of Hararge cattle at Haramaya University abattoir, Ethiopia by Takele Wolkaro, Yosef Tadesse, Mengistu Urge, Merga Bayisa

“…Hence, this model could be used by farmers and researchers to efficiently predict and monitor SW, and optimize productivity of the Hararge cattle herds in smallholder farming systems. …”
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Press Forward: Advancing Vaccine Production With High Hydrostatic Pressure Inactivation for Global Health Equity by Miss Martina Brandolini, Dr Alessandra Mistral De Pascali, Mr Giorgio Dirani, Mr Massimiliano Guerra, Ms Silvia Zannoli, Prof Pietro Rocculi, Dr Michele Morbarigazzi, Dr Davide Lelli, Dr Antonio Lavazza, Dr Francesca Battioni, Prof Monica Cricca, Prof Alessandra Scagliarini, Prof Vittorio Sambri

“…Discussion: Preliminary results show HHP efficacy in producing viral inactivates that can efficiently be used as immunogens in murine animal models. …”
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Reduced-dose deep learning iterative reconstruction for abdominal computed tomography with low tube voltage and tube current by Shumeng Zhu, Baoping Zhang, Qian Tian, Ao Li, Zhe Liu, Wei Hou, Wenzhe Zhao, Xin Huang, Yao Xiao, Yiming Wang, Rui Wang, Yuhang Li, Jian Yang, Chao Jin

“…Abstract Background The low tube-voltage technique (e.g., 80 kV) can efficiently reduce the radiation dose and increase the contrast enhancement of vascular and parenchymal structures in abdominal CT. …”
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Unlocking data: Decision-maker perspectives on cross-sectoral data sharing and linkage as part of a whole-systems approach to public health policy and practice by Emily Tweed, Kristina Cimova, Peter Craig, Mirjam Allik, Denise Brown, Mhairi Campbell, David Henderson, Charlie Mayor, Petra Meier, Nick Watson

“…Recommendations included a considered approach to which data sets should be shared; standardising oversight of data sharing; using existing data sets efficiently for different research purposes; investing in staff training; and promoting a public conversation about data sharing and linkage, and its benefits and risks.…”
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Super-Resolution of Landsat-8 Land Surface Temperature Using Kolmogorov–Arnold Networks with PlanetScope Imagery and UAV Thermal Data by Mahdiyeh Fathi, Hossein Arefi, Reza Shah-Hosseini, Armin Moghimi

“…To address these challenges, this study presents a novel approach to generate LST_SR maps by integrating Low-Resolution Landsat-8 LST (LST_LR) with High-Resolution PlanetScope images (I_HR) and UAV-derived thermal imagery (T_HR) using the Kolmogorov–Arnold Network (KAN) model. The KAN efficiently integrates the strengths of splines and Multi-Layer Perceptrons (MLPs), providing a more effective solution for generating LST_SR. …”
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A Machine Learning Approach to Differentiate Cold and Hot Syndrome in Viral Pneumonia Integrating Traditional Chinese Medicine and Modern Medicine: Machine Learning Model Developme... by Xiaojie Jin, Yanru Wang, Jiarui Wang, Qian Gao, Yuhan Huang, Lingyu Shao, Jiali Zhao, Jintian Li, Ling Li, Zhiming Zhang, Shuyan Li, Yongqi Liu

“…The developed model offers a novel approach for differentiating cold and hot syndromes in viral pneumonia, enabling practitioners to identify the syndrome quickly and efficiently, thereby supporting more informed clinical decision-making. …”
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