Screening and Development of New Inhibitors of FtsZ from M. Tuberculosis. by Bini Mathew, Judith Varady Hobrath, Larry Ross, Michele C Connelly, Hava Lofton, Malini Rajagopalan, R Kiplin Guy, Robert C Reynolds

“…Modeling studies suggest that these analogs bind in a specific region of the Mtb FtsZ polymer that differs from human tubulin and, in combination with a pharmacophore model presented herein, future hybrid analogs of the reported active molecules that more efficiently bind in this pocket may improve antibacterial activity while improving other drug characteristics.…”
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Advanced Suspension Techniques in Interferometric Gravitational Wave Detectors: An Overview by Vishnu G. Nair

“…This isolation is crucial for enabling the detectors to function efficiently at low frequencies, which directly impacts their capacity to detect distant events from the universe’s past. …”
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Percutaneous Nephrolithotomy: Current Clinical Opinions and Anesthesiologists Perspective by Indira Malik, Rachna Wadhwa

“…Therefore, it is mandatory to be familiar with the various complications, some of which may be life threatening and he should be able to manage them efficiently. The paper also analyses the advantages and drawbacks of the available options in anesthesia, that is, general and regional, both of which are employed for PCNL.…”
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Influence of Environmental Factors and Aggregates on Concrete Elasticity: Ultrasonic and Strength Testing by Mohammad Reza Hadidi, Yaghoub Mohammadi

“…The study also validates using UPV as a nondestructive method to efficiently evaluate concrete’s structural integrity. …”
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Position Control Using Trajectory Tracking and State Estimation of a Quad-rotor by Onur Sarıpınar, Muharrem Mercimek

“…To operate a quad-rotor aircraft efficiently and safely, fundamental issues such as mathematical modeling, control, and state estimation need to be studied. …”
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Organic Pollutants Removal from Petroleum Refinery Wastewater with Nanotitania Photocatalyst and UV Light Emission by Javad Saien, Fatemeh Shahrezaei

“…The identification analysis of the organic pollutants, provided by means of a GC/MS, equipped with headspace injection technique, showed that different petroleum compounds were degraded with high efficiencies.…”
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Realizing Strategic Approach in E-mail Marketing by A. S. Melekhova

“…Apart from that the author substantiates the idea that e-mail marketing is a promising and widely used trend in advertising and marketing, an effective tool of promotion in conditions of fast changing market environment and that it requires strategic approach to attain the set parameters of efficiency…”
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Optimized Method for Generating and Acquiring GPS Gold Codes by Khaled Rouabah, Salim Attia, Rachid Harba, Philippe Ravier, Sabrina Boukerma

“…We propose a simpler and faster Gold codes generator, which can be efficiently initialized to any desired code, with a minimum delay. …”
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Experimental study and prediction of abrasion resistance of hydraulic concrete by Qian Chen, Weizhun Jin, Xiaodan Tang, Hongxing Zhong, Qinghua Huang, Zhipeng Bai, Hongqiang Chu, Linhua Jiang

“…To predict the abrasion resistance of hydraulic concrete efficiently and accurately, this study analyzes the physical abrasion process of hydraulic concrete based on the underwater steel ball method. …”
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Deep learning based local feature classification to automatically identify single molecule fluorescence events by Shuqi Zhou, Yu Miao, Haoren Qiu, Yuan Yao, Wenjuan Wang, Chunlai Chen

“…In this study, we introduce DEBRIS (Deep lEarning Based fRagmentatIon approach for Single-molecule fluorescence event identification), a deep-learning model focusing on classifying local features and capable of automatically identifying steady fluorescence signals and dynamically emerging signals of different patterns. DEBRIS efficiently and accurately identifies both one-color and two-color single-molecule events, including their start and end points. …”
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Importance of weight loss maintenance and risk prediction in the prevention of type 2 diabetes: analysis of European Diabetes Prevention Study RCT. by Linda Penn, Martin White, Jaana Lindström, Annemieke Th den Boer, Ellen Blaak, Johan G Eriksson, Edith Feskens, Pirjo Ilanne-Parikka, Sirkka M Keinänen-Kiukaanniemi, Mark Walker, John C Mathers, Matti Uusitupa, Jaakko Tuomilehto

“…Pragmatic scalable interventions are needed, with evidence to efficiently target and monitor such interventions. We report pooled analyses of data from three European trial cohorts: to analyse T2D incidence, sustained weight loss and utility of risk predictors.…”
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Photonics Breakthroughs 2024: Multidimensional Integrated (de)Multiplexers for Optical Fiber Communications by Xianyi Feng, Wu Zhou, Hao Chen, Yuzhe Ma, Yeyu Tong

“…Compared with previous approaches, our device facilitates the selective excitation of different LP modes in an ultra compact manner, while preserving polarization diversity and competitive coupling efficiencies. …”
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Introduction to statistical simulations in health research by Matthias Briel, Ewout Steyerberg, Pamela Shaw, Tim P Morris, Harald Binder, Michal Abrahamowicz, Anne-Laure Boulesteix, Rolf HH Groenwold, Roman Hornung, Jörg Rahnenführer, Willi Sauerbrei, Victor Kipnis, Jessica Myers Franklin, Ingeborg Waernbaum

“…We aim to provide a first introduction to simulation studies for data analysts or, more generally, for researchers involved at different levels in the analyses of health data, who (1) may rely on simulation studies published in statistical literature to choose their statistical methods and who, thus, need to understand the criteria of assessing the validity and relevance of simulation results and their interpretation; and/or (2) need to understand the basic principles of designing statistical simulations in order to efficiently collaborate with more experienced colleagues or start learning to conduct their own simulations. …”
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Multiplex Evaluation of Biointerface-Targeting Abilities and Affinity of Synthetized Nanoparticles—A Step Towards Improved Nanoplatforms for Biomedical Applications by Mélanie Romain, Céline Elie-Caille, Dorra Ben Elkadhi, Olivier Heintz, Michaële Herbst, Lionel Maurizi, Wilfrid Boireau, Nadine Millot

“…The potentiality of the functionalized NPs to react efficiently with a protein monolayer is finally evaluated by grafting them on a protein covered chip, characterized by atomic force microscopy. …”
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Enhanced related-key differential neural distinguishers for SIMON and SIMECK block ciphers by Gao Wang, Gaoli Wang

“…In order to select input differences efficiently, we introduce a method that leverages weighted bias scores to approximate the suitability of various input differences. …”
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Ammonia Removal in Free-Surface Constructed Wetlands Employing Synthetic Floating Islands by Muwafaq H. M. Allami, Mick J. Whelan, Arnoud Boom, David M. Harper

“…Free water surface constructed wetlands (FSCWs) can be used to complement conventional waste water treatment but removal efficiencies are often limited by a high ratio of water volume to biofilm surface area (i.e. high water depth). …”
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Differential anti-glycan antibody responses in Schistosoma mansoni-infected children and adults studied by shotgun glycan microarray. by Angela van Diepen, Cornelis H Smit, Loes van Egmond, Narcis B Kabatereine, Angela Pinot de Moira, David W Dunne, Cornelis H Hokke

“…This resulted in the identification of differential glycan recognition profiles characteristic for the two different age groups, possibly reflecting differences in age or differences in length of exposure or infection.…”
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Generating Training Data for Deep Learning-Based Segmentation Algorithms by Projecting Existing Labels onto Additional Aerial Images by F. Kurz, N. Merkle, C. Henry, R. Bahmanyar, F. Rauch, J. Hellekes, V. Gstaiger, D. Rosenbaum, P. Reinartz

“…Existing labels can be efficiently reused by photogrammetric projections onto additional overlapping aerial or satellite images, enabling great variability in the appearance of the scenes based on differences in viewing angles and environmental conditions. …”
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Mahakala: A Python-based Modular Ray-tracing and Radiative Transfer Algorithm for Curved Spacetimes by Aniket Sharma, Lia Medeiros, George N. Wong, Chi-kwan Chan, Goni Halevi, Patrick D. Mullen, James M. Stone

“…We employ Google’s JAX framework for accelerated automatic differentiation, which can efficiently compute Christoffel symbols directly from the metric, allowing the user to easily and quickly simulate photon trajectories through non-Kerr spacetimes. …”
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Bridging currents: an interdisciplinary source-to-sea approach is essential to align regional and national priorities with the future global plastics treaty ambitions by Judith van Leeuwen, Kathrin Kopke, Lisa Devriese, Linda Del Savio, Andy M. Booth, Ben Boteler, Elisabeth Berglihn, Emily Cowan, Thomas Maes, Thomais Vlachogianni

“…These differences translate in different priorities and needs in terms of how to most efficiently and effectively reduce plastic pollution. …”
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