Analysis of nanomedicine primary tumor vs. metastasis targeting using clinical-stage core-crosslinked polymeric micelles by Larissa Yokota Rizzo, Federica De Lorenzi, Saskia von Stillfried, Seyed Mohammadali Dadfar, Qizhi Hu, Sanjay Tiwari, Claus-Christian Glüer, Marielle Thewissen, Felix Gremse, Stephan Rütten, Peter Boor, Wilhelm Jahnen-Dechent, Ruth Knüchel-Clarke, Fabian Kiessling, Cristianne J.F. Rijcken, Alexandros Marios Sofias, Twan Lammers

“…We show that nanomedicines effectively target metastases, albeit with lower efficiency than primary tumors. Tumor microenvironment analysis revealed that metastases are more vascularized than primary tumors but also present with higher levels of collagen crosslinking, thereby hindering nanomedicine accumulation. …”
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Investigation on Three-Hump Phosphor-Coated White Light-Emitting Diodes for Healthy Lighting by Genetic Algorithm by Ziquan Guo, Kai Liu, Lili Zheng, Tien-mo Shih, Yijun Lu, Tingzhu Wu, Yi Lin, Yuxue Zhang, Jianghui Zheng, Jie Chen, Lianxin Chen, Zhong Chen

“…White light with <italic>low circadian action factor (CAF)</italic> is propitious for bedroom lighting to help people relax and to promote sleep, whereas <italic>high&#x00A0;CAF</italic> white light is beneficial for increasing working efficiency in the working place. We obtain low CAF or high CAF according to different application occasions (such as bedroom lighting or office lighting), good Commission Internationale de L&#x2019;Eclairage color rendering index (<inline-formula><tex-math notation="LaTeX">$R_{a}$</tex-math></inline-formula>) or Illumination Engineering Society of North America color fidelity index (<inline-formula><tex-math notation="LaTeX">$R_{f}$</tex-math></inline-formula>), and color gamut index (<inline-formula><tex-math notation="LaTeX">$R_{g}$</tex-math></inline-formula>) or other color performances, and possibly high luminous efficacy of radiation (LER, <inline-formula><tex-math notation="LaTeX">$K$</tex-math></inline-formula>) at various correlated color temperatures (CCTs) from 2700 to 6500&#x00A0;K. …”
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Effect of <i>CTLA4</i> gene polymorphism on relapse probability among patients with acute leukemias after allogenic hematopoietic stem cells transplantation by D. S. Romaniuk, A. A. Khmelevskaya, M. Yu. Drokov, N. N. Popova, V. A. Vasilieva, L. A. Kuzmina, G. A. Efimov, E. N. Parovichnikova, V. G. Savchenko

“…Polymorphisms in the CTLA4 gene can affect its function and the efficiency of the antitumor response. The objective: to study the effect of non-synonymous single nucleotide polymorphism (nsSNP) c.49A&gt;G in the donor CTLA4 gene on tumor control in the recipient of allogeneic hematopoietic stem cells (HSC). …”
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Effects of Dietary β-Carotene on the Gonadal Color, Pigmentation, and Regulation Mechanisms in Sea Urchin Strongylocentrotus Intermedius by Weixiao Di, Yinuo Zhang, Huinan Zuo, Haijing Liu, Lina Wang, Jun Ding, Yaqing Chang, Rantao Zuo

“…Adult sea urchins (initial weight: 9.33 ± 0.21 g) of three cages were given one of the dry feeds with different doses of β-carotene (0 mg/kg, 150 mg/kg, 300 mg/kg) or fresh kelp (<i>Saccharina japonica</i>). …”
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Diagnostic value of serum TGF-β1 and CysC in type 2 diabetic kidney disease: a cross-sectional study by Yi Kang, Yi Kang, Yi Kang, Qian Jin, Mengqi Zhou, Huijuan Zheng, Huijuan Zheng, Xiaobin Li, Aoshuang Li, Aoshuang Li, Jing Wei Zhou, Jing Wei Zhou, Jie Lv, Jie Lv, Yaoxian Wang, Yaoxian Wang

“…The exploration of serum biomarkers holds promise for improving the efficiency and accuracy of early DKD diagnosis. This study aims to investigate the diagnostic value of transforming growth factor-β1 (TGF-β1) and cystatin C (CysC) in DKD patients.MethodsA total of 126 patients with type 2 diabetes mellitus (T2DM) diagnosed at Dongzhimen Hospital, Beijing University of Chinese Medicine, between May 2021 and March 2023 were enrolled. …”
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Chlorella and vegetable oil inclusion in diets for growing rabbits: effects on growth, digestibility, plasma metabolites, and caecal fermentations and microbiota by F. Bordignon, A. Trocino, P.J. Marín García, T. Larsen, G. Zardinoni, M. Molin, M. Birolo, P. Stevanato, G. Xiccato

“…On the other hand, increasing crude fat to 5% improved the overall feed efficiency.…”
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Identification of Metabolites of Ferulic Acid in Human after Oral Administration by Qian PAN, Wei LI, Yang YANG, Yong-qiang ZHAO, Li LIAN, Qing-qing CONG, Li-hong WANG, Yue-lin SONG, Qian HONG

“…Liquid chromatography coupled with mass spectrometry (LC-MS) combines the high-efficiency separation capabilities of LC with the powerful qualitative analysis advantage of MS, playing a vital and irreplaceable role in the in-depth study of chemical profiles in complex systems. …”
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CLP-Net: an advanced artificial intelligence technique for localizing standard planes of cleft lip and palate by three-dimensional ultrasound in the first trimester by Guangzhi He, Zhou Li, Zhiyuan Zhu, Tong Han, Yan Cao, Chaoyu Chen, Yuhao Huang, Haoran Dou, Lianying Liang, Fangmei Zhang, Jin Peng, Tao Tan, Hongmei Liu, Xin Yang, Dong Ni

“…Conclusions CLP-Net accurately locates three planes for CLP screening, aiding radiologists and enhancing the efficiency of ultrasound examinations.…”
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Centrifugation versus filtration-based cell salvage: impact on perioperative bleeding in cardiac surgery—the COLTRANE randomised clinical trial – study protocol by Christine Mouton, Nicolas Nesseler, Antoine Bénard, Mathieu Pernot, Alexandre Ouattara, Antoine Beurton, Alexandre Mansour, Victor-emmanuel Brett, Corinne Batsale, Anais Aitgougam, Anais Cordon, Aurelie Fresselinat, Geraldine Robert, Julien Imbault

“…The secondary outcomes include device efficiency and safety, perioperative haemostasis, lengths of intensive care unit and hospital stays, early postoperative morbidity and 30-day all-cause mortality. …”
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Biases and complementarity in gut viromes obtained from bulk and virus-like particle-enriched metagenomic sequencing by Yun Li, Chuqing Sun, Jiaying Zhu, Mingyan Geng, Min Li, Xing-Ming Zhao, Wei-Hua Chen

“…Particularly, VLP exhibits higher efficiency in obtaining more, longer, and more complete viral genomes. …”
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Gr-1 blockade remodels the immunosuppressive microenvironment induced by incomplete microwave ablation of hepatocellular carcinoma by Tian Huang, Hensong Cao, Shipeng Dai, Yonghua Zhu, Hanyuan Liu, Shuxian Zhu, Zhengqing Lu, Chuan Liu, Chengyu Lv, Zhouxiao Li, Jinhua Song, Han Zhuo

“…Abstract Background Ablation is one of the main methods for local treatment of hepatocellular carcinoma (HCC). Different from radiofrequency ablation (RFA), microwave ablation (MWA) is not limited by tissue conductivity, and can use multiple electrodes at the same time to improve ablation efficiency. …”
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Compact ultra-wide band two element vivaldi non-uniform slot MIMO antenna for body-centric applications by Sahar Saleh, Tale Saeidi, Nick Timmons, Bader Alali, Faroq Razzaz, Ayman A. Althuwayb

“…The proposed VNSMA provides good, measured outcomes of S11 < −11.08 dB with wide BW of 12.5 GHz (2.33–14.83 GHz) covering high isolation of −23 dB (for most of frequency band), moderate-high gain of 5.89 dBi, radiation efficiency of 66–90 %, low Envelope Correlation Coefficient (ECC) of 0.002 and high diversity gain (DG) of 9.99 dBi, stable radiation patterns, and average group delay of 1.2 ns. …”
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Bacteriostatic Activity and Resistance Mechanism of <i>Artemisia annua</i> Extract Against <i>Ralstonia solanacearum</i> in Pepper by Tiantian Du, Weiping Zhu, Chenning Zhang, Xiaomin Liang, Yinghua Shu, Jingyun Zhou, Mengyu Zhang, Yuxuan He, Jincai Tu, Yuanjiao Feng

“…Plant-derived pesticides exhibit advantages of high efficiency and broad spectrum when compared to traditional chemical pesticides. …”
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Dose–response study of a fenugreek-based antibiotic alternative in Bábolna Tetra-SL chicks (1–42 days old) with mixed bacterial infections by Ádám Kerek, Ádám Kerek, Ábel Szabó, Péter Ferenc Dobra, Krisztina Bárdos, Krisztina Bárdos, Bettina Paszerbovics, Zsófia Bata, Viviána Molnár-Nagy, Ákos Jerzsele, Ákos Jerzsele, László Ózsvári, László Ózsvári

“…Statistical analyses included mixed-effect logistic regression for mortality, mixed-effect linear models for weight gain, two-way ANOVA for feed efficiency, and random effects continuation ratio models for Salmonella isolation.ResultsSignificant interactions for Group:Day and Sex:Day in weight gain were identified (p &lt; 0.0001 for both). …”
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Genetic diversity analysis and core collection construction of Phyllanthus emblica based on SSR markers by WANG Jianchao, ZHANG Xiaoyan, ZHANG Lijie, LI Tao, XIE Lixue

“…[Objective] The genetic diversity and core collection construction of Phyllanthus emblica were investigated using SSR molecular markers, in order to provide a scientific basis for preservation, genetic breeding and efficient utilization of the germplasm resources. [Methods] The experimental materials were collected from P. emblica Germplasm Resource Sub-Center, National Tropical Plants Germplasm Resource Center. …”
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Suplementación con bloques de melaza-urea en dietas a base de forrajes en la alimentación de conejos by Quintero de Vallejo Victoria E.

“…In feed efficiency there were significant differences (p &lt; .05) among treatments, being better for CC (3.1), for forages was better Trichantera gigantea (4.5), for rice bran was better to use it (4.02). …”
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Experiment of double grits scribing 2D SiCf/SiC composite by Jinzhu GUO, Yao LIU, Youzhe WANG, Dong WANG

“…ObjectivesTo improve the grinding quality and efficiency, reveal the material removal mechanism of SiCf/SiC composites, and determine the coupling effect among abrasives during grinding.MethodsFirstly, uniaxial tensile, shearing, and bending experiments of SiC fiber bundles are conducted to observe damage modes. …”
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Modeling sunflower yield and soil water–salt dynamics with combined fertilizers and irrigation in saline soils using APSIM and deep learning by Qingfeng Miao, Dandan Yu, Haibin Shi, Zhuangzhuang Feng, Weiying Feng, Zhen Li, José Manuel Gonçalves, Isabel Maria Duarte, Yuxin Li

“…Using the APSIM model, we simulated crop growth and soil moisture under different organic fertilizer application ratios in mildly to moderately saline soils. …”
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Effect of TiH2 addition on grinding performance of Cu3Sn intermetalliccompound diamond wheels by Keqiao HE, Shuaipeng CHEN, Xiyue KANG, Yuehui HE

“…For the precision grinding of high hardness and high wear-resistant materials, superhard material grinding wheels are required to possess high processing efficiency and durability. Intermetallic compound bond diamond grinding wheels have the wear resistance of metal grinding wheels and the self-sharpness of ceramic grinding wheels simultaneously, but they still lacks of sharpness or shape retention when machining hard and brittle materials at high loads and high speeds. …”
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Analyzing Relationship between Urban Form and Disaster Resilience at Tehran Metropolis Neighborhoods by ESfandiar Zebardast, Mohammad mehdi Azizi, Elnaz baghernejhad

“…The results of this analysis show that different urban form components have various and even contrasting influences on resilience. …”
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