Metformin carbon dots-based osteogenic and protein delivery system to promote bone regeneration in periodontitis by Jingjing Wei, Kai Wang, Yongkai Li, Jiao Huang, Ping Deng, Xianbo Xia, Cong Yang, Ling Xu, Junji Xu

“…To address this, we developed an osteogenic and protein-delivery composite hydrogel system based on metformin carbon dots (MCDs) to enhance the osteogenic potential of hPDLSCs under inflammatory conditions. …”
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Phenotype and function of human monocytes remain mainly unaffected by very small superparamagnetic iron oxide particles by Sari Hussein, Sari Hussein, Anja Andrea Kühl, Laura Golusda, Laura Golusda, Christina Plattner, Nadine Heinze, Nadine Heinze, Gregor Sturm, Christian Freise, Heike Traub, Mathias Schannor, Zlatko Trajanoski, Matthias Taupitz, Britta Siegmund, Daniela Paclik, Daniela Paclik

“…This study examines nanoparticle effects on human blood cells focusing on monocytes in vitro as a first step toward clinical application. Whole blood and monocytes from healthy donors and patients with inflammatory bowel disease were treated with VSOP in vitro and analyzed for changes in their transcriptome, phenotype and function. …”
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Ticks (Acari: Ixodidae) and tick-borne diseases in Cameroon: Current understanding and future directions for more comprehensive surveillance by Yannick Ngnindji-Youdje, Michel Lontsi-Demano, Adama Zan Diarra, Juluis Foyet, Timolèon Tchuinkam, Philippe Parola

“…Knowledge of their biodiversity and distribution in any given area is a crucial step towards a better implementation of control strategies. …”
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Modeling of Global and Individual Kinetic Parameters in Wheat Straw Torrefaction: Particle Swarm Optimization and Its Impact on Elemental Composition Prediction by Ismael Urbina-Salas, David Granados-Lieberman, Martín Valtierra-Rodríguez, Claudia Adriana Ramírez-Valdespino, David Aarón Rodríguez-Alejandro

“…The global parameters are calculated from experiments conducted at 250 °C, 275 °C, and 300 °C, and the individual parameters are obtained by adjusting experimental points at each temperature. A two-step kinetic model was used and optimized to achieve exceptional adjustment accuracy (98.073–99.999%). …”
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A Janus Amyloid-like Nanofilm Inhibits Colorectal Cancer Postoperative Recurrence and Abdominal Adhesion via Synergistic Enzyme Cascade by Man Zhang, Junhao Kou, Zhenyi Song, Ling Qiu, Chunzhao Yang, Qi Xue

“…In this study, based on amyloid-like protein self-assembly technology, a novel Janus protein film was developed. The protein film encapsulates glucose oxidase (GOx) and catalase (CAT), which is named PTL@GC. …”
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Comprehensive approaches to design efficient gRNA for SDN1-CRISPR/Cas9 genome editing in wheat by Tushadri Singh, Tushadri Singh, H. M. Mamrutha, Rajender Singh, J. P. Jaiswal, Zeenat Wadhwa, Rakesh Kumar, Omvir Singh, O. P. Ahlawat, Ratan Tiwari

“…Furthermore, the removal of regulation on site-directed nuclease1- (SDN1) and SDN2-developed products in many countries has made it a more revolutionary technology for adoption in crop improvement. …”
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Systematic literature review on Calcium Pyrophosphate Deposition (CPPD) nomenclature: condition elements and clinical states— A Gout, Hyperuricaemia and Crystal-Associated Disease... by Georgios Filippou, Antonella Adinolfi, Emilio Filippucci, Nicola Dalbeth, Robert Terkeltaub, Tristan Pascart, Edoardo Cipolletta, Silvia Sirotti, Charlotte Jauffret, Sara Tedeschi, Daniele Cirillo, Luca Ingrao, Alessandro Lucia

“…Objectives The Gout, Hyperuricaemia and Crystal-Associated Disease Network (G-CAN) has developed a calcium pyrophosphate deposition (CPPD) nomenclature project. …”
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A Mg2+-dependent high-yield method for extracting high-molecular-weight genomic DNA from a single planarian specimen by Ao Li, Bingrui Sun, Ying Zhang, Ping Yu, Jicheng Qu, Hongkuan Deng, Qiuxiang Pang, Fengtang Yang

“…Results In this study, we have developed a more robust protocol for preparing HMM gDNA, with high yields and quality, from a single D. japonica. …”
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Self-assembled nanosheets of biocompatible polymers as universal cell-membrane mimic to block viral infection by Ranen Etouki, Na Xing, Mathias Dimde, Chuanxiong Nie, Ievgen S. Donskyi, Kai Ludwig, Ehsan Mohammadifar, Rainer Haag

“…Viruses cause severe damage to society due to seasonal and pandemic outbreaks; therefore, developing new antivirals is urgently needed. Multivalent virus inhibitors are promising broad-spectrum antivirals, as they can block the initial step of viral infection by mimicking the structure of the cell receptors on the host cell membrane. …”
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High-Performance Liquid Chromatography Quantification of Glyphosate, Aminomethylphosphonic Acid, and Ascorbate in Culture Medium and Microalgal Cells by Juan Ostera, Valentina Olmos, Susana Puntarulo, Julián Bonetto, Gabriela Malanga

“…Several analytical methods have been developed for GLY quantification. Most of them use high-performance liquid chromatography (HPLC) coupled with detection by mass spectrometry (MS) and include a derivatization step to decrease the polarity of the herbicide to improve detection. …”
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Circulating mitochondrial biomarkers in acute coronary syndrome by Andrea Iboleon-Jimenez, María J. Sánchez-Quintero, María J. Sánchez-Quintero, María J. Sánchez-Quintero, Ada D. M. Carmona-Segovia, Ada D. M. Carmona-Segovia, Ada D. M. Carmona-Segovia, Bélen Sojo, Bélen Sojo, Ana María Fernández-Ramos, Ana María Fernández-Ramos, Luis García-Rodríguez, Luis García-Rodríguez, Ana I. Molina-Ramos, Ana I. Molina-Ramos, Ana I. Molina-Ramos, José Manuel García-Pinilla, José Manuel García-Pinilla, José Manuel García-Pinilla, José Manuel García-Pinilla, Manuel Jimenez-Navarro, Manuel Jimenez-Navarro, Manuel Jimenez-Navarro, Manuel Jimenez-Navarro, Almudena Ortega-Gomez, Almudena Ortega-Gomez, Almudena Ortega-Gomez

“…BackgroundAcute coronary syndrome (ACS) is the leading cause of mortality in developed countries. Mitochondrial dysfunction is a hallmark of various cardiometabolic diseases, including ACS. …”
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Multimodal mobile brain and body imaging for quantification of dance motor sequence learning by Russell W. Chan, Victoria Lakomski, Johannes V.R. Pannermayr, Emma Wiechmann, Jan-Willem J.R. van ‘t Klooster, Willem B. Verwey

“…It can advance motor learning by providing more profound insights into coordination dynamics, movement execution, balance, and decision-making. We have developed a modified DSP methodology that replaces keyboard pressing with dance-stepping, allowing simultaneous electroencephalography (EEG), behavioral, and kinematic recordings to quantify neurophysiological and motor dynamics. …”
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Quantitative characterization of different occurrence states in medium maturity continental shale oil: a case study on eocene Shahejie formation shales, Qikou Sag, East China by Wenya Jiang, Wenya Jiang, Wenya Jiang, Yuchen Liu, Lijin Gao, Guangdi Liu, Guangdi Liu, Jianyuan Feng

“…Shale oil with different lithologic facies and different occurrence states in the core section of the Shahejie Formation in the Qikou Sag was quantitatively evaluated. An improved four-step pyrolysis scheme of 300°C, 375°C, 400°C, and 600°C was developed to experimentally analyze shale oil core samples. …”
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BBEST practices: Intentional efforts to identify elusive flow-ecology thresholds by Mark B. Lueders, Ryan A. McManamay, Diane Le Bouille, Kayla Garrett, Lydia Roush, Stephen Powers, David Young, Preston Bean, Kevin Mayes, Ryan Smith, Joseph F. Trungale

“…Developing and discerning flow-ecology relationships, particularly identifying the limits of hydrologic alterations on aquatic ecosystems, is critical for effective water resource management. …”
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The integration of microelectronic and photonic circuits on a single silicon chip for high-speed and low-power optoelectronic technology by Rajeev Gupta, Ajay Kumar, Manoj Kumar, Rajesh Singh, Anita Gehlot, Purnendu Shekhar Pandey, Neha Yadav, Kailash Pandey, Ashish Yadav, Neha Gupta, Ranjeet Brajpuriya, Shalendra Kumar, Ajay Singh Verma, Tanuj Kumar, Yongling Wu, Zheng Hongyu, Abhijit Biswas, Ajay Mittal, Aniruddha Mondal, Romanov Oleksandr Ivanovich

“…., have been discussed. This would be a step forward in creating standalone silicon photonic devices, strengthening the possibility of single on-chip nanophotonic integrated circuits. …”
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Neuron Network Modeling of Intensification of Isogumulone Extraction in a Rotary Pulse Generator by Anton V. Shafrai, Elena A. Safonova, Dmitry M. Borodulin, Yana S. Golovacheva, Sergey A. Ratnikov, Wasfie Barsoom Wasef Kerlos

“…The present research objective was to develop an artificial neural network capable of predicting the content of isogumulone in a hop extract at given technological parameters of the rotary pulse generator. …”
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Strategies to improve academic motivation in undergraduate nursing students in Iran: a qualitative content analysis by Mozhdeh Taheri Afshar, Arash Ziapour, Fakhreddin Chaboksavar, Shakiba Lajmiri, Murat Yıldırım, Fatemeh Mohammadkhah

“…By using the strategies to increase academic motivation resulting from this study, an effective step can be taken in this field. Also Understanding these influential strategies can play a significant role in educational and career planning and decision-making, selecting appropriate educational and clinical measures and facilities in the university and students’ future work environment, developing educational and career regulations, effective interaction with learners, ultimately increasing the effectiveness of professors’ teaching and better teaching and learning activities.…”
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Major Causative Bacteria of Dairy Cow Mastitis in the Inner Mongolia Autonomous Region, China, 2015–2024: An Epidemiologic Survey and Analysis by Hongmei Zhao, Ting Guo, Yaping Zhou, Fengmiao Zhao, Yajie Sun, Yuchen Wang, Yuchen Bian, Guangyuan Tian, Chunxia Wu, Qi Cui, Xue Zhou, Jinlei Cui, Han Si, Yongqing Hao

“…This indicates that the current prevention strategies for infectious pathogens are effective. As a next step, it will be important to develop new strategies specifically targeting environmental pathogenic microorganisms.…”
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Purification of Biodiesel from Waste Cooking Oil Using Bentonite as Dry Washing Agent by Nanda Suriaini, Tika Thalia Febriana, Andesta Yulanda, Adisalamun Adisalamun, Yanna Syamsuddin, Muhammad Dani Supardan

“…The process of biodiesel purification is an important step in getting biodiesel products that meet specifications as a substitute for fossil-based fuels. …”
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Learning the factors controlling mineral dissolution in three-dimensional fracture networks: applications in geologic carbon sequestration by Aleksandra A. Pachalieva, Aleksandra A. Pachalieva, Jeffrey D. Hyman, Daniel O’Malley, Gowri Srinivasan, Hari Viswanathan

“…We characterize the features controlling these processes by developing a machine learning framework to extract their relevant impact. …”
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