A New Research Tool for Use in Sharks and Rays: Relevance of Reproductive Hormone Levels in the Skin of Small-Spotted Catshark (<i>Scyliorhinus canicula</i>) by Annaïs Carbajal, Isabel González Lobato, Clara Agustí, Marta Muñoz-Baquero, Paula Serres-Corral, Manel López-Béjar

“…The present study marks a significant step forward in validating the use of skin biopsies for measuring reproductive steroid hormones in sharks. …”
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A Quadruplex RT-qPCR for the Detection of Porcine Sapelovirus, Porcine Kobuvirus, Porcine Teschovirus, and Porcine Enterovirus G by Biao Li, Kaichuang Shi, Yuwen Shi, Shuping Feng, Yanwen Yin, Wenjun Lu, Feng Long, Zuzhang Wei, Yingyi Wei

“…In order for the differential detection of these four viruses, specific primers and TaqMan probes were designed for the conserved regions in the 5′ untranslated region (UTR) of these four viruses, and one-step quadruplex reverse-transcription real-time quantitative PCR (RT-qPCR) for the detection of PSV, PKV, PTV, and EV-G was developed. …”
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Automatic detection of human gait events: a simple but versatile 3D algorithm by Théo Vancanneyt, Camille Le Moal, Maxence Blard, Juliette Lenoir, Nicolas Roche, Céline Bonnyaud, Fabien Dubois

“…Conclusion Accurately identifying gait events is the first critical step in providing reliable gait analysis parameters for clinicians. …”
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The UK consensus supporting effective introduction of novel treatments for multiple myeloma in the National Health Service by Rakesh Popat, Supratik Basu, Sarah Henshaw, Kamaraj Karunanithi, Karthik Ramasamy, Inderjit Singh, Anish Tailor, Ian Walker, Tim Warren, Noreen Ali, Charles Duffield, Gordon Cook

“…The objective was to develop consensus statements for the effective implementation of BCMA BsAbs for relapsed or refractory MM patients within the National Health Service (NHS). …”
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Mechanical robust and thermal insulated rPET microcellular foam via supercritical CO2 foaming cross-linked photovoltaic backsheet by Jiajia Gu, Miao Lu, Wenhao Xie, Jiyun Jia, Chen Liu, Guochen Yang, Binghua Ma, Zhiyuan Chen, Chul B. Park, Ruiyan Zhang

“…With the assistance of two-step supercritical CO2 foaming technology, the rPET microcellular foam with high compressive strength and thermal insulated performance can be developed. …”
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Protocol for detection and monitoring of post-stroke cognitive impairment through AI-powered speech analysis: a mixed methods pilot study by Ravi Shankar, Effie Chew, Effie Chew, Effie Chew, Anjali Bundele, Anjali Bundele, Amartya Mukhopadhyay, Amartya Mukhopadhyay

“…Qualitative analysis will follow an inductive thematic approach to explore acceptability and usability of speech-based screening.DiscussionThis study represents a critical step toward developing speech-based digital biomarkers for PSCI detection that are sensitive, culturally appropriate, and clinically feasible. …”
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Intracranial volume segmentation for neurodegenerative populations using multicentre FLAIR MRI by Justin DiGregorio, Giordano Arezza, Adam Gibicar, Alan R. Moody, Pascal N. Tyrrell, April Khademi

“…In this work, we develop and evaluate 2 traditional and 8 deep learning algorithms for ICV segmentation in FLAIR MRI. …”
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Radiomics in the differential diagnosis of glioblastoma under the primary neurooncoimaging conditions by Nikita E. Maslov, Daria A. Valenkova, Alexander M. Sinitсa, Gennadiy E. Trufanov, Vladimir M. Moiseenko, Alexander Yu. Efimtsev, Vera V. Chernobrivtseva

“…The aim of our study is to develop a radiomics model for IDH mutation status prediction, which can be applied to primary diagnostic imaging in patients with suspected adult-type diffuse gliomas. …”
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Mediators of the association between allergic diseases and bronchiectasis: A bi-directional univariable and multivariable Mendelian randomization study and mediation analysis by Ping-An Zhang, MD, Jie-Lin Wang, MD, Shi-Yan Fu, BD, Hua-Lian Luo, BD, Run-Dong Qin, PhD, Jing Li, MD

“…Additionally, the mediating effects of immune cells, inflammatory proteins, metabolites, and gut microbiota on the relationship between allergic disorders and bronchiectasis were assessed through two-step TSMR and multivariate MR analysis. Results: Our study revealed that allergic asthma, allergic rhinitis, atopic conjunctivitis, and atopic dermatitis all increased the risk of developing bronchiectasis, with no causal relationship identified in the reverse direction. …”
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Optimization for Rapid Detection of E. coli O157:H7 Using Real-Time Loop-Mediated Isothermal Amplification by Alaleh Valiallahi, Mehdi Zeinoddini, Shirin Jalili

“…Conclusion: The rapid, sensitive, one-step-visually developed LAMP assay could be of interest for screening functions in food analytical laboratories without special equipment or trained personnel.…”
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Design and Optimization of Collimator for Preclinical Single-photon Emission Computed Tomography Scanner: A Monte Carlo Study by Mohammad Mirdoraghi, Behnoosh Teimourian Fard, Olga Kochebina, Hojjat Mahani, Mohammad Reza Ay

“…The purpose of this investigation was to implement and validate a MC model for a preclinical single-photon emission computed tomography (SPECT) known as high-resolution SPECT II (HiReSPECT II) machine developed in our laboratory and also optimize different collimator materials and geometries for improving the sensitivity and spatial resolution. …”
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Composite Narratives with Arts-Based Analysis of Undergraduate Engineering Students’ Stress and Social Supports to Identify Structural Barriers by Jeanne Sanders, Joseph Mirabelli, Eileen Johnson, Karin Jensen

“…Background: Undergraduate engineering students experience high stress and exhibit help-seeking behaviors less than non-engineering peers. Developing a deeper, comprehensive understanding of their experiences is a critical step to identifying potential changes to reduce their stress. …”
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The use of vacuum fine needle aspiration biopsy of small formations in the diagnosis of thyroid cancer by A. O. Tagil, A. V. Borsukov

“…Due to high negative pressure (up to –0.8 bar), single-step retrieval of cytologic material is performed which leads to a decrease in the number of nondiagnostic and undetermined cytologic conclusions by 11.7 and 1.9 %, respectively.…”
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Combined Trans-Epithelial PRK and PTK for Treatment of Corneal Opacity Following Acanthamoeba Keratitis: A Case Report by Buonamassa R, Addabbo G, Pignatelli F, Niro A, Passidomo F

“…After 1 year from the infection, the patient returned to our attention for developing a central corneal scar and decreased corrected distance visual acuity (CDVA) in the left eye. …”
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AI-assisted evidence screening method for systematic reviews in environmental research: integrating ChatGPT with domain knowledge by Chen Zuo, Xiaohao Yang, Josh Errickson, Jiayang Li, Yi Hong, Runzi Wang

“…Combining AI with domain knowledge provides an exploratory step to evaluate feasibility of AI-assisted evidence screening, especially for diverse, large volume, and interdisciplinary studies. …”
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Assessment of Medication Use by Publics in Sulaimani Province by Kamal Aziz Enayat, Mariwan Abdulla Hama Salih, Muhammed Babakir-Mina

“…Drug uses is a multi-step process starting from consulting doctor, prescribing, ordering and using via individual either public or healthcare staff for therapeutic reasons. …”
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Large Language Models for Pre-mediation Counseling in Medical Disputes: A Comparative Evaluation against Human Experts by Min Seo Kim, Jung Su Lee, Hyuna Bae

“…The Claude 3.5 Sonnet model processed each counseling request through a five-step chain-of-thought pipeline. Thirty-eight experts evaluated the chatbot’s responses against the original human expert responses, rating them across four dimensions on a 5-point Likert scale. …”
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Using routine surveillance data to estimate the epidemic potential of emerging zoonoses: application to the emergence of US swine origin influenza A H3N2v virus. by Simon Cauchemez, Scott Epperson, Matthew Biggerstaff, David Swerdlow, Lyn Finelli, Neil M Ferguson

“…<h4>Conclusions</h4>We have developed a simple approach with limited data requirements that enables robust assessment of the risks posed by emerging zoonoses. …”
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Hazelnut allergome overview and Cor a gRNAs identification by Ciro Gianmaria Amoroso, Giuseppe Andolfo

“…The recent availability of several Corylus genomes provided opportunities to explore allergome variability, and thus to develop hypoallergenic varieties using modern biotech approaches. …”
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Identifying genetic variants that affect viability in large cohorts. by Hakhamanesh Mostafavi, Tomaz Berisa, Felix R Day, John R B Perry, Molly Przeworski, Joseph K Pickrell

“…A number of open questions in human evolutionary genetics would become tractable if we were able to directly measure evolutionary fitness. As a step towards this goal, we developed a method to examine whether individual genetic variants, or sets of genetic variants, currently influence viability. …”
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