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11461
Separation of bivalent anti-T cell immunotoxin from Pichia pastoris glycoproteins by borate anion exchange
Published 2003-08-01“…By using this property of the immunotoxin in the presence of sodium borate, we successfully developed a 3-step purification procedure: (i) Butyl-650M hydrophobic interaction chromatography, (ii) Poros 50 HQ anion exchange chromatography in the presence of borate, and (iii) HiTrapTM Q anion exchange chromatography. …”
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11462
Description of survival data extended to the case of competing risks: a teaching approach based on frequency tables
Published 2013-10-01“…In the case of a composite <em>end-point</em>, the next step is to account for the presence of competing risks. …”
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11463
Pembrolizumab and olaparib in a cisplatin-refractory testicular cancer patient with a high TMB: first case report
Published 2025-03-01“…In addition, the patient developed an immune-related pneumonitis with a fatal outcome 3 months later. …”
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11464
Effect of disinfection agents and quantification of potentially viable Leptospira in fresh water samples using a highly sensitive integrity-qPCR assay.
Published 2021-01-01“…Detecting the presence of pathogenic bacteria in aquatic environments and their capacity to resist various inactivation processes are research fields that need to be further developed. In addition, the methods used for detecting and enumerating Leptospira still need to be improved. …”
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11465
A Cumulant-Based Method for Acquiring GNSS Signals
Published 2024-09-01“…Global Navigation Satellite Systems (GNSS) provide positioning, velocity, and time services for civilian applications. A critical step in the positioning process is the acquisition of visible satellites in the sky. …”
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11466
Highly solvent-stable polyimide ultrafine fibrous membranes fabricated by a novel ultraviolet-assisted electrospinning technique via organo-soluble intrinsically negative photosens...
Published 2021-01-01“…A novel fabrication methodology for polyimide (PI) UFMs based on soluble PIs with high solvent durability was developed. As fiber-forming agents, a series of intrinsically negative photosensitive polyimides (PSPIs) with solubility in organic solvents were synthesized by the one-step thermal polymerization of 3,3′,4,4′-benzophenonetetracarboxylic dianhydride (BTDA) with three ortho-alkyl-substituted diamine monomers, namely, 3,3′,5,5′-tetramethyl-4,4′-diaminodiphenylmethane (TMMDA, for PI-1), 3,3′-dimethyl-5,5′-diethyl-4,4′-diaminodiphenylmethane (DMDEDA, for PI-2), and 3,3′,5,5′-tetraethyl-4,4′-diaminodiphenylmethane (TEMDA, for PI-3), respectively. …”
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11467
Inefficient Toll-like receptor-4 stimulation enables Bordetella parapertussis to avoid host immunity.
Published 2009-01-01“…The recognition of bacterial lipopolysaccharide (LPS) by host Toll-like receptor (TLR)4 is a crucial step in developing protective immunity against several gram negative bacterial pathogens. …”
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11468
Exploring a Rare Case of Idiopathic Scrotal Calcinosis: A Case Report
Published 2025-04-01“…We present the case of a 37-year-old male who developed idiopathic scrotal calcinosis, a rare disorder marked by calcium deposition in the scrotal skin. …”
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11469
Closing special education bachelor's programs in the Kingdom of Saudi Arabia: an analytical perspective and solutions
Published 2025-05-01“…One of the most important results of the study is that 65% of the faculty disagree with Saudi universities closing their SEBP, while 35% support it as a positive step toward updating curricula and addressing teacher competency issues. …”
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11470
A two‐stage, four‐layer robust optimisation model for distributed cooperation in multi‐microgrids
Published 2024-12-01“…The results demonstrate the practical utility and efficiency of the developed approach in addressing distributed cooperation challenges in microgrid systems with energy storage.…”
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11471
Thermodynamic analysis and intelligent modeling of statin drugs solubility in supercritical carbon dioxide
Published 2025-08-01“…Abstract Evaluating the solubility of various drugs in supercritical CO2 is a fundamental step in developing a supercritical process for formulating new pharmaceuticals. …”
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11472
Unraveling the impact of social media involvement on public health participation in China: mediating roles of social support, social trust, and social responsibility
Published 2025-02-01“…Guided by social capital theory and conservation of resources theory, this study develops an analytical model to explore the effect of social media involvement on public health participation mediated by social support, social trust and social responsibility. …”
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11473
(W/O/W) Double Emulsions-Filled Chitosan Hydrogel Beads for Topical Application
Published 2025-06-01“…The aim of this study was to develop double emulsions-filled chitosan hydrogel beads for topical application and to elucidate their skin penetration behavior. …”
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11474
Re-introduction of India ink testing as a low-cost laboratory diagnostic for cryptococcosis among HIV infected patients in Southern Mozambique: An implementation research protocol.
Published 2025-01-01“…This study uses implementation science methods framed by the Dynamic Adaption Process (DAP) and the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) conceptual frameworks to develop a multi-phase, stepped-wedged trial using mixed-methods approaches. …”
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11475
Privacy attack in federated learning is not easy: an experimental study
Published 2025-07-01“…Although numerous privacy attack FL algorithms have been developed, most are designed to reconstruct private data from a single step of calculated gradients. …”
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11476
Safe and Efficient Preparative Approach to Chiral α-Chloroketones Based on In-Flow Generated Diazomethane
Published 2024-12-01“…As a proof-of-concept, we demonstrate its application in the three-step synthesis of chiral α-chloroketones from N-protected amino acids. …”
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11477
Construction of Gait Adaptation Model in Human Splitbelt Treadmill Walking
Published 2009-01-01“…In order to construct the gait adaptation model of such human splitbelt treadmill walking, we proposed a simple control model and made a newly developed 2D biped robot walk on the splitbelt treadmill. …”
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11478
The 2022 Italian general election: a political shock or the new normal?
Published 2023-06-01“…Instead, it marked a further step in the emergence of a ‘new political normal’ characterised by volatility, fragmentation, mainstreaming of populist ideas and actors, polarisation and the reframing of socio-economic and socio-cultural cleavages. …”
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11479
Interior Point Method for Solving Fuzzy Number Linear Programming Problems Using Linear Ranking Function
Published 2013-01-01“…Recently, various methods have been developed for solving linear programming problems with fuzzy number, such as simplex method and dual simplex method. …”
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11480
“Mechanics hand” as vaccine related adverse event after COVID-19 vaccination
Published 2024-12-01“…His joint pain symptoms worsened over 4 weeks and developed blackish pigmentation of both hands predominantly involving palms to present as mechanics hands. …”
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