Whole-genome sequencing reveals transmission pattern and drug resistance of Mycobacterium tuberculosis intra- or inter-hosts by Feng Ding, Wanfei Liu, Chi Wu, Chi Wu, Wensi Zhang, Shuyan Chen, Shuyan Chen, Wenjie Lai, Wenjie Lai, Jiayao Qu, Jiayao Qu, Qiang Lin, Shuihua Lu, Jiuxin Qu, Jiuxin Qu

“…A novel method based on heterozygous SNPs and two-sample Kolmogorov–Smirnov test were developed and identified 12 (4.26%) samples as mixed infection samples. …”
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Cumulative blood pressure load as a predictor of arterial stiffness progression and incident diabetic kidney disease: a multicenter longitudinal study by Cong Liu, Bangqun Ji, Yao Liang, Juan Shi, Yufan Wang, Tingyu Ke, Li Li, Dong Zhao, Yuancheng Dai, Qijuan Dong, Fengmei Xu, Ying Peng, Weiqing Wang, Qidong Zheng, Yifei Zhang

“…The predictive ability of cumulative BP load calculated under different clinically recommended targets was compared using adjusted R squared (adjusted R2) for continuous outcomes and net reclassification improvement (NRI) for binary outcomes. …”
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Effectiveness of early intervention and combination treatment with monoclonal antibodies and antivirals in oncohematological patients with SARS-CoV-2: a retrospective experience by Silvia Di Bari, Francesco Izzo, Livia Bresciani, Giulia Mancarella, Silvia Garattini, Andrea Gasperin, Daniela Di Trento, Alessandra Grimaldi, Alberico Parente, Raffaella Marocco, Anna Carraro, Blerta Kertusha, Tiziana Tieghi, Cosmo Del Borgo, Serena Vita, Mariasilvia Guardiani, Caterina Pasquazzi, Alessandra Spagnoli, Danilo Alunni Fegatelli, Miriam Lichtner, Miriam Lichtner

“…Overall, 101 patients were recruited, 76 (75.24%) patients developed pneumonia, and 16 (15.84%) patients died from any cause. …”
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Exploring Machine Learning Models for Vault Safety in ICL Implantation: A Comparative Analysis of Regression and Classification Models by Qing Zhang, Qi Li, Zhilong Yu, Ruibo Yang, Emmanuel Eric Pazo, Yue Huang, Hui Liu, Chen Zhang, Salissou Moutari, Shaozhen Zhao

“…Regression and classification models were developed using gradient boosting, random forest, and CatBoost algorithms. …”
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Oxidative damage to lipids improves with Omega-5 fatty acid supplementation treatment in patients with severe alcoholic hepatitis by Moisés Martínez-Castillo, Jacqueline Cordova-Gallardo, Abigail Hernandez-Barragan, Marisela Hernández-Santillán, Diana Mungía-Ramos, Froylan Martínez-Sánchez, Daniel Santana-Vargas, Gabriela Gutiérrez-Reyes

“…Alcoholic hepatitis (AH) is a severe clinical event that develops in patients with ALD and active alcohol consumption, and it has a high mortality rate within 30 days. …”
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Assessing the impact of multi-source environmental variables on soil organic carbon in different land use types of China using an interpretable high-precision machine learning meth... by Feng Wang, Ruilin Liang, Shuyue Li, Meiyan Xiang, Weihao Yang, Miao Lu, Yingqiang Song

“…With the increase of soil depth, the SOC content of all land types decreased continuously, and the values indicate a left-skewed non-normal distribution. …”
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Applying design to design: demonstrating how to create a human-centered design session interview guide for use with adolescents by Macarena Kruger, Macarena Kruger, Andrea B. Goldschmidt, Adrian Ortega, Adrian Ortega, Abigail Wharton, Danielle A. N. Chapa, Erin R. Stalvey, Isabel R. Rooper, Isabel R. Rooper, Katrina T. Obleada, Katrina T. Obleada, Graham C. Miller, Graham C. Miller, Andrea K. Graham, Andrea K. Graham

“…Next, we piloted the prototype with members of our team and a technology-savvy adolescent (“evaluate”) to refine it prior to administration with the target audience (“refine and develop”). Our internal needs assessment identified that we needed to learn adolescents’ preferences for technology (e.g., desired features), clinical content (e.g., areas for specialized support), delivery (e.g., coaching), and developmental relevance (e.g., focus on self-regulation). …”
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Analysis of the spatiotemporal evolution pattern of the synergistic relationship among high temperature, drought, and CHTDs in climate transition zones by Hui Su, Chunxiao Wu, Shuai Zhou, Xiangxu Song, Jiaqi Tian, Xiaoqing Han, Xiao Zhang, Ting Zhang

“…The high temperature events from May to July will cover most of the central and eastern parts of the basin and continue to develop into heatwave events (defined as three consecutive days of high temperature). …”
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Cost-effectiveness analysis of the Assessment of Burden of Chronic Conditions (ABCC) tool in primary care in the Netherlands by Manuela A Joore, Esther A Boudewijns, Mascha Twellaar, Onno CP van Schayck, Merel L Kimman, Loraine HL Peters, Annerika HM Gidding-Slok, Lotte CEM Keijsers, Jean WM Muris

“…Recognising the multifaceted nature of chronic conditions, the Assessment of Burden of Chronic Conditions (ABCC) tool was developed to support person-centred care, by facilitating shared decision-making and self-management. …”
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Global, regional, and national burden of breast, cervical, uterine, and ovarian cancer and their risk factors among women from 1990 to 2021, and projections to 2050: findings from... by Yingying Li, Wenfu Song, Ping Gao, Xutao Guan, Bing Wang, Liutong Zhang, Yaxuan Yao, Yaqiong Guo, Yi Wang, Shiqing Jiang, Shiling Sun

“…These projections are essential for developing targeted prevention and control strategies, thereby informing more effective public health interventions. …”
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Fluid balance dynamics and early postoperative outcomes in orthotopic liver transplantation: a prospective cohort study by Suzana Margareth Lobo, Pedro Saggioro Paulucci, Lucas Martins Tavares, Graziela Benardin Luckemeyer, Luana Fernandes Machado, Neymar Elias de Oliveira, Silvia Prado Minhoto, Rita Cassia Alves Silva, Renato Ferreira da Silva, Marlon Souza Freitas, Francisco Ricardo Marques Lobo, Joana Berger-Estilita

“…The strong predictive value of SOFALIVER scores for all-cause mortality highlights the importance of early and continuous monitoring of liver function. Future multicenter randomized controlled trials are needed to validate these findings and develop optimized fluid management protocols for OLT patients.…”
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Studies of Phase Transformation Kinetics in the System of Nanocrystalline Iron/Ammonia/Hydrogen at the Temperature of 350 °C by Means of Magnetic Permeability In Situ Measurement by Walerian Arabczyk, Rafał Pelka, Agnieszka Brzoza-Kos, Ireneusz Kocemba, Paulina Rokicka-Konieczna, Katarzyna Skulmowska-Polok, Kamila Klimza, Zofia Lendzion-Bieluń

“…In the first area, a solution of α-Fe (N) is formed with a continuous and insignificant change of the crystal lattice parameters of the iron lattice. …”
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Optimal control strategies supported by system dynamics modelling: a study on hookworm disease in China by Huihui Zhu, Jinxin Zheng, Jilei Huang, Mizhen Zhang, Changhai Zhou, Tingjun Zhu, Hongchun Tian, Xiaohong Wu, Yang Liu, Bo Zhong, Hong Xie, Liping Zhang, Lei Tie, Jingwen Luo, Xiaoqin Mao, Bin Zhang, Xiu Deng, Suping Zhang, Menbao Qian, Shizhu Li, Xiaonong Zhou

“…The results were used to develop an optimized strategy for hookworm disease control. …”
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Coastline variations on a section of a coast dominated by cliffs: Past, current and future changes in the municipality of São Francisco de Itabapoana, Brazil by Elizabeth Santos Pereira, Camila Américo dos Santos, Ruan Vargas, Ivandro Patrick de Oliveira Coutinho, Kátia Leite Mansur, Jhone Caetano de Araújo, Marcus Felipe Emerick Cambra, Elisa Elena de Souza Santos, Guilherme Borges Fernandez, Pedro Michelotti, Fábio Ferreira Dias

“…For the present time frame, the extraction of the coastline from 1984 to 2022 showed the evolution of the entire coastline of the municipality, both positive and negative, showing that the active cliff, which is on Lagoa Doce beach, is eroding continuously. The results show that in the reconstruction of the past, the paleofault was active, indicating that the ridges developed later. …”
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Postpartum depression and associated factors among childbearing women from the recent Demographic and Health Survey data of Mozambique: Multilevel analysis by Mamaru Melkam, Bezawit Melak Fente, Yohannes Mekuria Negussie, Zufan Alamrie Asmare, Hiwot Altaye Asebe, Beminate Lemma Seifu, Alemayehu Kasu Gebrehana, Sintayehu Simie Tsega, Meklit Melaku Bezie, Angwach Abrham Asnake

“…Educational level should be improved to have a continuous and sharp change in maternal depression after delivery.…”
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Measuring growth, resistance, and recovery after artemisinin treatment of Plasmodium falciparum in a single semi-high-throughput assay by Mackenzie A. C. Sievert, Tarrick Qahash, Puspendra P. Singh, Douglas A. Shoue, Lisa A. Checkley, Katelyn Vendrely Brenneman, Zione Cassady, Sudhir Kumar, Xue Li, François H. Nosten, Timothy J. C. Anderson, Ashley M. Vaughan, Jeanne Romero-Severson, Michael T. Ferdig

“…Resistance measured at 120 h continually shows the most consistent phenotype for ring stage susceptibility. …”
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Implementation and effectiveness of Teleneonatology for neonatal intensive care unit consultations in the Netherlands: a hybrid type III implementation pilot by Josephine HL Wagenaar, Julia Broos, Ron HT van Beek, Henrike Pas, Martijn Suurveld, Anne Jacobs, Fredrik Bodell, Sylvia A Obermann-Borst, Florian Cassel, Maaike S. Kleinsmann, Saba Hinrichs-Krapels, Irwin KM Reiss, H Rob Taal

“…The TeleNeo program was developed and continuously improved during the pilot using co-creation with HCP and parents to enable embedding in care pathways and working routines. …”
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In-depth analysis of the safety of CAR-T cell therapy for solid tumors by Jiayi Dong, Jiayi Dong, Jiayi Dong, Jiayi Dong, Jiexiong Wu, Ye Jin, Ye Jin, Ye Jin, Ye Jin, Ye Jin, Zhu Zheng, Zhu Zheng, Zhu Zheng, Zhu Zheng, Zhu Zheng, Ting Su, Ting Su, Ting Su, Ting Su, Ting Su, Lijuan Shao, Lijuan Shao, Lijuan Shao, Lijuan Shao, Lijuan Shao, Jiaxin Bei, Jiaxin Bei, Jiaxin Bei, Jiaxin Bei, Size Chen, Size Chen, Size Chen, Size Chen, Size Chen

“…Continued monitoring for long-term effects will also be paramount in improving patient outcomes and maintaining their quality of life. …”
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Increased risk of chronic diseases and multimorbidity in middle-aged and elderly individuals with early vision, hearing, or dual sensory impairments: insights from prospective coho... by Yaoling Wang, Fang Cheng, Niuniu Hou, Yuting Tan, Shaomin Zhang, Yanbing Hou, Wen Guo, Jin Peng, Wei Li, Jinhui Wu

“…Conclusions This study provides evidence from epidemiological or genetic perspectives demonstrates that early exposure to HI/VI/DSI increases the risk of developing chronic diseases. These findings underscore the need for continuous monitoring and timely intervention for SI to manage chronic disease risks in aging populations.…”
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Diagnosis and Treatment of Gastroesophageal Reflux Disease (Clinical Guidelines of the Russian Gastroenterological Association, Russian Scientific Medical Society of Internal Medic... by V. T. Ivashkin, A. S. Trukhmanov, I. V. Maev, O. M. Drapkina, M. A. Livzan, A. I. Martynov, T. L. Lapina, A. V. Paraskevova, D. N. Andreev, O. P. Alexeeva, S. A. Alekseenko, A. Yu. Baranovsky, O. V. Zayratyants, O. Yu. Zolnikova, O. B. Dronova, I. L. Kliaritskaia, N. V. Korochanskaya, Yu. A. Kucheryavyy, S. N. Mammaev, M. F. Osipenko, S. S. Pirogov, E. A. Poluektova, D. E. Rumyantseva, R. G. Sayfutdinov, O. A. Storonova, Yu. P. Uspenskiy, I. B. Khlynov, V. V. Tsukanov, A. A. Sheptulin

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