Acute and subacute toxicity evaluation of ZhenzhuXiaoji decoction in preclinical models: implications for safe clinical use by Songzhe Li, Shuchang Bao, Lingyun Cai, Baolong Li, Yue Sun, Yue Sun, Yang Sun

“…BackgroundZhenzhuXiaoji Decoction (ZZXJD) is a traditional Chinese medicine formulation composed of five herbs: Ligustrum lucidum, Curcuma zedoaria, Prunella vulgaris, Hedyotis diffusa, and Glycyrrhiza uralensis, developed for the treatment of hepatocellular carcinoma (HCC). …”
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Clinical and functional characterization of the GABRB3 p.Met80Val variant in early-onset epilepsy with long-term follow-up by Ran Hua, Junhong Jiang, Baotian Wang, Zihao Zhu, Juan Wang, De Wu, Li Yang

“…Results A heterozygous de novo GABRB3 variant (NM_000814.6: c.238 A > G, p.Met80Val) was identified in a 16-year-old female who developed absence seizures at one year and exhibited persistent EEG abnormalities over the subsequent decade. …”
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Multidisciplinary input improves the management outcomes of immune thrombocytopenia in pregnancy by Sanika Dalvi, Sarah Davis, Drew Solan

“…Care pathways with joint clinics between haematology, obstetrics and other specialties should be continued or developed to increase adherence to guidelines and improve patient care.…”
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Predictive value of the triglyceride-glucose index for coronary artery bypass grafting-acute kidney injury patients by Biao Hou, Xuejian Hou, Dong Liu, Taoshuai Liu, Kui Zhang, Yang Li, Ran Dong

“…Logistic regression analysis confirmed that the TyG index was an independent risk factor for AKI following CABG, both as a continuous variable (OR 1.034 [95% CI 1.017–1.050], p < 0.001) and when grouped by quartiles. …”
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Arbuscular mycorrhizal fungal genotype and nuclear organization as driving factors in host plant nutrient acquisition and stable carbon storage by Robert Ferguson, Ken Mugambi, Matthew Villeneuve‐Laroche, Cynthia M. Kallenbach, Pedro M. Antunes, Nicolas Corradi

“…Societal Impact Statement It is crucial to develop strategies for reducing our continued excessive global increases in fertilizer applications and to offset CO2 emissions. …”
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Metástase cerebral: tratamento paliativo com radiocirurgia Brain metastasis: palliative treatment with radiosurgery by Sérgio L. Faria, Luis Souhami, Jean-Paul Bahary, Jean-Louis Caron, Jean-Guy Villemure, André Olivier, Brenda Clark, Ervin B. Podgorsak

“…Only 4 patientes (7%) developed late complications related to the treatment. …”
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Comprehensive Analysis of VOCs in an Industrial Harbor City: Spatiotemporal Distribution, Health Risk, and Potential Sources by Thi-Hieu Le, Chung-Shin Yuan, Chitsan Lin, Zhi-Ping Hsu, I-Hsin Hsu, Lin-Chi Wang

“…Air VOCs samples were collected continuously in 24 h by canister and analyzed by GC/MS with pre-concentration systems according to U.S. …”
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pilot study of combined transvertebral magnetic and transcutaneous stimulation for the rehabilitation of combat acute spinal cord injuries by Oleksandr Kulyk, Ivan Mazurchuk, Valeriia Polousova, Anna Pshenychna, Oksana Yarmolenko

“…Material and methods: We have analysed 154 cases of severe combat spinal cord injury, followed continuously for at least 12 months from the start of neurorehabilitation. …”
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Linking the life stages of fish into a habitat-ecological flow assessment scheme under climate change and human activities by Yiming Zhang, Wensheng Wang, Siyi Yu

“…In this framework, blocked index (BI) and percentages of the longest continuous river reach (PLR) were proposed to quantify the habitat connectivity conditions during migration stage. …”
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Self-administered dual-task training reduces balance deficits and falls among community-dwelling older adults: a multicentre parallel-group randomised controlled trial with economi... by Wai-Chi Chan, Cynthia Huijun Chen, Mohammad Jobair Khan, Kenneth N. K Fong, Thomson Wai-Lung Wong, William Wai-nam Tsang, Stanley Winser

“…Following the intervention phase, the participants will continue unsupervised home-based exercises for 6 months. …”
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Fatal Mycobacterium avium meningitis in an HIV-negative Vietnamese man: a case report by Van Thanh Nguyen, Le Hong Van, Guy Thwaites, Nguyen Thuy Thuong Thuong, Pham Kieu Nguyet Oanh, Do Dang Anh Thu, Nguyen Thanh Dung, Van Thi Xuan Quynh, Nguyen Tran Thuong Dinh, Ho Dang Trung Nghia

“…Blood cultures at two sites, cerebrospinal fluid cultures for bacteria and fungi, and human immunodeficiency virus Ag/Ab test were negative. The patient was continuously administered meropenem with the addition of azithromycin, rifampin, and ethambutol. …”
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What does the impurity variability at the microscale represent in ice cores? Insights from a conceptual approach by P. Larkman, R. H. Rhodes, N. Stoll, C. Barbante, C. Barbante, P. Bohleber, P. Bohleber

“…In this work, a computational framework has been developed, integrating insights from 2D imaging to aid the interpretation of 1D signals. …”
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Impact of an in-consult patient decision aid on decisional quality, involvement, and health outcome for patients with severe hip or knee osteoarthritis – a study protocol for a mul... by Trine Ahlmann Pedersen, Martin Lindberg-Larsen, Charlotte Myhre Jensen, Signe Timm, Karina Dahl Steffensen, Claus Varnum

“…A total of 19 orthopaedic surgeons will be randomised 1:1, stratified by centre, to either continue standard consultations without the PtDA or implement SDM using the PtDA. …”
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Modelling of childbearing progression among women living with HIV in Ibadan, Nigeria by Ahmed Olagunju, Joshua O. Akinyemi, Rotimi Afolabi, Olutosin A. Awolude

“…Progression to fourth and subsequent births showed a continued decline, with the likelihood of a fourth birth being 82% lower and a fifth or sixth birth 85% lower. …”
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Methods for Indirect Treatment Comparison: Results from a Systematic Literature Review by Bérengère Macabeo, Arthur Quenéchdu, Samuel Aballéa, Clément François, Laurent Boyer, Philippe Laramée

“…Clearer international consensus and guidance on the methods to use for different ITC techniques is needed to improve the quality of ITCs submitted to HTA agencies. ITC techniques continue to evolve quickly, and more efficient techniques may become available in the future.…”
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Clinical Characteristics and Prognostic Factors of Severe COVID-19 by Yang Y, Huang Z, Pei Y, Huang Y, Chen C, Zhou T

“…Moreover, non-survivors exhibited a higher propensity to develop acute kidney injury (AKI) and receive mechanical ventilation (MV) and continuous renal replacement therapy (CRRT). …”
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VTE risk assessment and management in admitted patients at a private hospital in Dubai- A quality improvement project by Akil Gafarbhai Parmar, Salman Muhammad Soomar, Rafiw Mahen, Asma Binte Shahid, Nasser Alharazi, Faiza Akhlaque, Zeeshan Khan

“…Mean and SD were calculated for the quantitative variables, and frequency and percentages were calculated for the categorical variables. Bar graphs were developed to visually display the data. Results The mean ± SD age was 46.15 ± 15.81 years. …”
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Enhancing Harmony Search Metaheuristic Algorithm for Coverage Efficiency, Test Suite Reduction, and Running Time in Combinatorial Interaction Testing by Aminu Aminu Muazu, Ahmad Sobri Hashim

“…Optimization has developed powerful algorithms for solving complex problems efficiently. …”
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Effect of rock bolt pretension on anchoring and bearing characteristics of fractured rock mass by Xiaoqing WANG

“…In order to obtain the influence mechanism of rock bolt pretension on the anchoring and bearing characteristics of fractured rock mass, the numerical simulation method of gravel bolting and the pretension imposing method were developed. Gravel bolting laboratory and numerical tests under low and high pretensions were carried out, respectively. …”
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Manipulated Slow Release of Florfenicol Hydrogels for Effective Treatment of Anti-Intestinal Bacterial Infections by Luo W, Zhang M, Jiang Y, Ma G, Liu J, Dawood AS, Xie S, Algharib SA

“…However, the hydrogels began to be destroyed after 5 minutes in simulated intestinal fluid (SIF), and this decomposition was continuous. With the decomposition of the structure of florfenicol hydrogels, the encapsulated florfenicol was also slowly released, and thus, it achieves the slow-release effect. …”
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