Digitally deployed, GP remote consultation video intervention that aims to reduce opioid prescribing in primary care: protocol for a mixed-methods evaluation by Nick Hex, Christopher Price, Yu Fu, Ben Allen, Tracy Finch, Denis Martin, Cormac G Ryan, Alan M Batterham, Niki Jones, Ewan Maule

“…A pilot intervention using smartphone video messaging has been developed to remotely explain the rationale for opioid reduction and facilitate self-initiation of support. …”
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A Novel Metabolic Risk Classification System Incorporating Body Fat, Waist Circumference, and Muscle Strength by Carlos Raúl Robledo-Millán, María Regina Diaz-Domínguez, Ari Evelyn Castañeda-Ramírez, Efrén Quiñones-Lara, Sebastián Valencia-Marín, Ricardo Xopán Suárez-García, Nely Gisela López-Desiderio, Claudio Adrían Ramos-Cortés, Areli Marlene Gaytán Gómez, Juan Manuel Bello-López, Héctor Iván Saldívar-Cerón

“…<b>Background:</b> As metabolic diseases continue to rise globally, there is a growing need to improve risk assessment strategies beyond traditional measures such as BMI and waist circumference, which may fail to identify individuals at risk. …”
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Epidemiology and impact of device-specific infections on patients receiving left ventricular assist devices by Amit Iyengar, MD MSE, Jason Feinman, MD, Joyce Jiang, BS, Cindy Song, BA, Spencer Kim, BA, Alvin Mathew, MD, Sophia Golec, MD, Aarti Rao, MD, Ankitha Radakrishnan, MD, Michaela Asher, MPhil, David Rekhtman, BS, John DePaolo, MD PhD, Noah Moss, MD, Shinobu Itagaki, MD, Anelechi Anyanwu, MD, Joyce Wald, DO, Marisa Cevasco, MD MPH, Aditya Parikh, MD

“…Results: Among 206 LVAD recipients, 71 (34.5%) developed an LSI. Predominant organisms were Staphylococcus (47.9%), Pseudomonas (15.5%), and Serratia (8.5%). …”
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Data extraction methods for systematic review (semi)automation: Update of a living systematic review [version 3; peer review: 3 approved] by Rebecca Elmore, Luke A. McGuinness, James Thomas, Julian P. T. Higgins, Ailbhe N. Finnerty Mutlu, Babatunde K. Olorisade, Lena Schmidt

“…A total of 112 (96%) publications developed classifiers for randomised controlled trials. …”
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Near-Real-Time Global Thermospheric Density Variations Unveiled by Starlink Ephemeris by Zhuoliang Ou, Jiahao Zhong, Yongqiang Hao, Ruoxi Li, Xin Wan, Kang Wang, Jiawen Chen, Hao Han, Xingyan Song, Wenyu Du, Yanyan Tang

“…In recent years, the Starlink constellation, developed and deployed by SpaceX, has emerged as the world’s largest low Earth orbit (LEO) satellite constellation, with over 6000 satellites in operations as of October 2024. …”
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Long‐Circulating Nanobody Confers Durable Prophylaxis against Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Infection by Geetha Jyothi Vaskuri, Gang Ye, Fan Bu, Dong Yang, Colleen B. Jonsson, Hailey Turner‐Hubbard, Sydney Winecke, Alise Mendoza, Fang Li, Chalet Tan

“…Breakthrough infections in vaccinated population and continuous emergence of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) variants make it imperative to develop more efficacious medical countermeasures. …”
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Early Acute Kidney Injury and Its Association With Survival in Patients With Metastatic Non‐Small‐Cell Lung Cancer Treated With Front‐Line Immunotherapy‐Based Therapies by Mingjia Li, Po‐Lan Su, Songzhu Zhao, Grace Cheng, Nicholas Jones, Kenneth Chian, Natalie Johns, Adam Khorasanchi, Adeoluwa Adeluola, Annastasia Petouhoff, Daniel J. Spakowicz, Lai Wei, Xiaoying Wang, Christopher Coss, Mitch A. Phelps, Lingbin Meng, Yuanquan Yang, Alexa Meara, Mohamed I. Elsaid, Jinesh Gheeya, Logan Roof, Asrar Alahmadi, Regan M. Memmott, Jacob Kaufman, Kai He, Carolyn J. Presley, Peter G. Shields, David P. Carbone, Gregory A. Otterson, Jason Prosek, Dwight H. Owen

“…The hazard ratio (HR) for death within 12 months for patients who developed early AKI was 1.733 (95% CI 1.060–2.835, p = 0.026). …”
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Nursing care for a pediatric patient with small-for-size syndrome after liver transplantation (1例小儿肝移植术后并发小肝综合征的护理体会) by CHEN Rui (陈锐), ZHAO Ruiling (赵瑞玲), YANG Jing (杨静), MA Jing (马晶)

“…This article outlines the nursing process for a 12-year-old pediatric patient who developed small-for-size syndrome after liver transplantation. …”
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Quantifying Land Subsidence Probability and Intensity Using Weighted Bayesian Modeling in Shanghai, China by Chengming Jin, Qing Zhan, Yujin Shi, Chengcheng Wan, Huan Zhang, Luna Zhao, Jianli Liu, Tongfei Tian, Zilong Liu, Jiahong Wen

“…The proportions of cumulative subsidence above 100 mm and between 50 and 100 mm are significantly lower for 2017–2021 compared to those for 2012–2016, indicating a continuous slowdown in land subsidence in Shanghai. (2) Using the cumulative subsidence from 2017–2021 as a measure of posterior probability, the probability distribution of land subsidence under the first scenario ranges from 0.02 to 0.97. …”
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Contribution of Fc-dependent cell-mediated activity of a vestigial esterase-targeting antibody against H5N6 virus infection by Zhiqiang Zheng, Su Hui Catherine Teo, Suganya Cheyyatraivendran Arularasu, Zhehao Liu, Nur Khairiah Mohd-Ismail, Chee Keng Mok, Chee Bing Ong, Justin Jang-hann Chu, Yee-Joo Tan

“…The highly pathogenic avian influenza A (H5N6) virus has caused sporadic human infections with a high case fatality rate. Due to the continuous evolution of this virus subtype and its ability to transmit to humans, there is an urgent need to develop effective antiviral therapeutics. …”
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Epidemic season 2023–2024: the palette of ARVI pathogens in some territories of the Russian Federation and WHO regions by Elena I. Burtseva, Nataliya V. Breslav, Evgenia A. Mukasheva, Kirill G. Krasnoslobodtsev, Elena S. Kirillova, Svetlana V. Trushakova, Irina A. Komarova, Elena L. Feodoritova, Anna D. Panova, Lidiya B. Kisteneva, Irina N. Khlopova, Irina S. Kruzhkova, Anastasia S. Krepkaia, Ekaterina O. Morozova, Anna V. Ignatieva, Andrey B. Komissarov, Igor N. Tyurin, Aleksey A. Samkov, Nataliya A. Antipjat

“…Cases of human infection with avian and swine influenza viruses continue to be registered. Conclusion. Against the background of a relatively low circulation of new SARS-CoV-2 variants in the 2023-2024 season, epidemic activity of influenza viruses was recorded in the countries of the Northern hemisphere at the traditional time. …”
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Building a virtual community of practice for medical students: The Global Emergency Medicine Student Leadership Program by Ashley Pickering, Andrés Patiño, Stephanie C. Garbern, Dania Abu‐Jubara, Alexandra Digenakis, Anthony Rodigin, Michaela Banks, Kimberly Herard, Stacey Chamberlain, Elizabeth L. DeVos

“…The GEM‐SLP VCoP is built around multiple forms of mentorship, monthly mentee‐driven didactics, academic projects, and continued engagement of program graduates in VCoP leadership. …”
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Association of early postoperative serum magnesium with acute kidney injury after cardiac surgery by Chao Xiong, Sheng Shi, Liang Cao, Hongbai Wang, Lijuan Tian, Yuan Jia, Min Zeng, Jianhui Wang

“…Higher serum magnesium level was associated with a higher risk of developing postoperative AKI (adjusted odds ratio (OR), 1.46 per 1 mg/dL increase; 95% confidence interval (CI), 1.31–1.62; p<.001). …”
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Evaluating GPT-4o in infectious disease diagnostics and management: A comparative study with residents and specialists on accuracy, completeness, and clinical support potential by Lili Zhan, Xiumin Dang, Zhenghua Xie, Chaoying Zeng, Weixing Wu, Xiaoyu Zhang, Li Zhang, Xinjian Cai

“…Participants answered 75 questions—comprising true/false, open-ended, and clinical case-based scenarios—developed according to international guidelines and clinical practice. …”
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The prognostic value of admission serum uric acid for acute kidney injury: a two-center retrospective analysis by Shuo Huang, Shuo Huang, Shuo Huang, Shuo Huang, Shuo Huang, Linger Tang, Linger Tang, Linger Tang, Linger Tang, Linger Tang, Lingyi Xu, Lingyi Xu, Lingyi Xu, Lingyi Xu, Lingyi Xu, Jinwei Wang, Jinwei Wang, Jinwei Wang, Jinwei Wang, Jinwei Wang, Xizi Zheng, Xizi Zheng, Xizi Zheng, Xizi Zheng, Xizi Zheng

“…Subgroup analysis was conducted in terms of estimated glomerular filtration rate (eGFR).ResultsAmong 62,775 patients enrolled from PKUFH, 1,866 patients developed AKI (3.0%). The RCS plot showed a U-shaped association between SUA and AKI. …”
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Five-Year Outcomes of Patients with Pompe Disease Identified by the Pennsylvania Newborn Screen by Hayley A. Ron, Owen Kane, Rose Guo, Caitlin Menello, Nicole Engelhardt, Shaney Pressley, Brenda DiBoscio, Madeline Steffensen, Sanmati Cuddapah, Kim Ng, Can Ficicioglu, Rebecca C. Ahrens-Nicklas

“…One LOPD patient was started on ERT at age 4.5 months. Continued data collection on these patients is critical for developing management guidelines, including timing of ERT and improved genotype–phenotype correlation.…”
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Efficacy and safety of dual-targeted therapy for refractory inflammatory bowel disease: a retrospective case series from three tertiary general hospitals in China by Xiaoying Wang, Ye Fang, Jiakai Luo, Yongli Ye, Shuyan Li, Dingting Xu, Xiaoqi Zhang, Yi Jiang, Qiao Yu, Yan Chen

“…Adverse events included ustekinumab-associated arthralgia and alopecia in one UC patient and tofacitinib-related allergic purpura in another, both of which were subsequently transitioned to monotherapy. Two CD patients developed infections (Clostridium difficile and bacterial intestinal infection) at 3 months, were treated with oral antibiotics, and successfully continued their original DTT regimens.ConclusionOur findings suggest that dual-target therapy demonstrates promising efficacy and an acceptable safety profile in refractory IBD patients. …”
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Association between Prognostic Nutritional Index and Contrast-Associated Acute Kidney Injury in Patients Complicated with Chronic Kidney Disease and Coronary Artery Disease by Xiaoli Dong, Bo Wang, Shiqun Chen, Jin Liu, Yu Xia, Shouhong Wang, Bin Li, Sheng Wang, Ming Ying, Huanqiang Li, Ziling Mai, Yongquan Yang, Jiyan Chen, Yong Liu, Tiehe Qin, Ning Tan

“…PNI was analysed from the high level to low level as a continuous variable and categorical variable which was divided into four groups by quartile. …”
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Predictive modeling and interpretative analysis of risks of instability in patients with Myasthenia Gravis requiring intensive care unit admission by Chao-Yang Kuo, Emily Chia-Yu Su, Hsu-Ling Yeh, Jiann-Horng Yeh, Hou-Chang Chiu, Chen-Chih Chung

“…Additionally, disease duration, a key continuous variable, was inversely correlated with the risk of ICU admission. …”
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Chemotherapy-based split stereotactic body radiation therapy for borderline resectable and locally advanced pancreatic cancer: study protocol of a prospective, single-arm phase II... by Xiao-bo Li, Rong Zheng, Heguang Huang, Congfei Wang, Xiaoxue Huang, Qingliang Lin, Daxin Huang, Benhua Xu

“…All study procedures were developed in order to assure data protection and confidentiality.Trial registration number NCT04289792.…”
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