Garlic-Derived Exosome-Like Nanovesicles: A Promising Natural Nanotherapy for Periodontitis via PHGDH/PI3K/AKT-Mediated Metabolic and Inflammatory Regulation by Yu C, Liu Y, Yu X, Liu J, Cao P, Liu G, Cai Y, Zhang Y, Luan Q

“…Garlic-derived exosome-like nanovesicles (GaELNs), as a natural therapeutic agent, have demonstrated significant therapeutic effects in conditions such as colitis, liver dysfunction, osteoarthritis, and adipose tissue inflammation, yet their potential in treating periodontitis has not been explored.Methods: In this study, GaELNs were extracted using a simplified and rapid method and characterized for their morphology and concentration. …”
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CYP2C9 Polymorphism Study in Patients with Acute Back Pain and its Impact on the Effectiveness of Treatment with the Non-Steroidal Anti-Inflammatory Drugs by Maslova I., Mykhailovska N., Slobodin T.

“…All patients underwent a genetic test – the determination of the allelic variants CYP2C9*2 and CYP2C9*3 CYP2C9 gene with polymerase chain reaction (PCR). …”
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Patient-informed outpatient intervention to improve pregnancy outcomes through connections to social services: protocol for the BETTER randomised controlled trial by William A Grobman, Laura J Rush, Ann Scheck McAlearney, Anna Bartholomew, Timothy R Huerta, Sarah R MacEwan, Nicole R Thomas, Lindsey N Sova, Leah Roth, Kaprea F Johnson

“…Black individuals have a 2–3-fold higher risk of APOs and a similarly increased risk of maternal morbidity and mortality compared with White individuals. Adverse social determinants of health (SDoH) are at the root of this disparity and contribute to it through multiple mechanisms. …”
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Application of dry electrodes in supercapacitors and lithium-ion batteries by Guolei ZHANG, Keliang ZHANG, Yabin AN, Chen LI, Guanwei LIU, Xianzhong SUN, Changzhou YUAN, Kai WANG, Xiong ZHANG, Yanwei MA

“…With the increasing demand for electrochemical energy storage, the lithium-ion battery industry faces new challenges, such as improving production efficiency, reducing energy consumption, and enhancing battery performance, especially for next-generation batteries. …”
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Relación entre la calidad del sueño y manifestaciones tempranas del síndrome de sobreentrenamiento físico en futbolistas colombianos (Relationship between sleep quality and early m... by Martín Hernán Bonilla Obando, Nelson Fernelly Gonzalez Cetina, Sandra Patricia Cárdenas Ojeda, Diana Paola López Velandia

“…Materials and Methods: A descriptive cross-sectional study was conducted involving male soccer players in Colombia. …”
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Clinical course and outcomes of COVID-19 infection in liver transplant recipients: single-center cross-sectional study by S. E. Voskanyan, A. I. Sushkov, V. S. Rudakov, D. S. Svetlakova, M. V. Popov, A. N. Pashkov, M. Muktarzhan, A. S. Lukianchikova

“…Despite this, there were no large Russian studies of COVID-19 course and outcomes in liver transplant recipients.The study purpose was to determine prevalence, clinical course, severity, outcomes of COVID-19, as well as to assess the safety and efficiency of vaccination for disease prevention in liver transplant recipients.Material and methods. 260 recipients (71% of all patients at risk of COVID-19 disease) who underwent liver transplantation at State Research Center – Burnasyan Federal Medical Biophysical Center from May 2010 to September 2021 were included in a single-center cross-sectional study. …”
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Proposing a two-stage screening approach to distinguish between transient and enduring postnatal depressive symptoms: A prospective cohort study by Johanne Smith-Nielsen, Ida Egmose, Stephen Matthey, Maria Stougård, Sophie Reijman, Mette Skovgaard Væver

“…This approach significantly improves referral efficiency and minimizes over-pathologization, enhancing clinical practice in perinatal mental health.…”
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The relation of changes in intraoperative EEg and ECog with age, anamnesis duration and outcome of surgical treatment in children with symptomatic epilepsy by A. B. Kozlova, M. B. Korsakova, N. A. Arkhipova, P. A. Vlasov, A. G. Melikyan, L. V. Shishkina, E. L. Masherov

“…To reveal relation of change in intraoperative electroencephalography (EEG), electrocorticography (EсoG) with age of patients, the anamnesis duration, localization and type of pathology, the result of treatment.   Materials and methods. 64 patients with symptomatic epilepsy operated at N.N. …”
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Sustainability index analysis of organic fertilizer production from paunch manure and rice straw waste by A.D. Santoso, F.D. Arianti, E.S. Rohaeni, B. Haryanto, M.D. Pertiwi, L.P. Panggabean, A. Prabowo, S. Sundari, S.P. Wijayanti, I.N. Djarot, F.D. Kurniawati, F.L. Sahwan, T. Prasetyo, A. Barkah, T.A. Adibroto, R. Ridlo, I. Febijanto, A.A. Wasil, S. Lusiana, R. Rosmeika, R.B. Heryanto

“…These include water use and raw material efficiency, potential business scale increase, market absorption, the potential for public unrest, the manager or worker level of expertise in the manufacture of organic fertilizer as well as the process used to determine its quality and output.CONCLUSION: The proposed inquiry conducted within the context of this study identified the pivotal factors that influenced organic fertilizer supply framework as the quality, quantity, and market absorption of organic production. …”
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10-YEARS ANALYSIS OF CRYOBAG FRACTURE IN A LARGE INVENTORY OF CELLULAR THERAPY PRODUCTS: RATES AND RISK FACTORS by AR Belisário, LT Mendonça, RK Andrade, MC Martins, LA Costa, KL Prata

“…This study aimed to investigate the incidence and determinants of cryobag fractures within a large inventory of cellular therapy products in Brazil. …”
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Effects of Supplementary Irrigation and some Stress Modifiers (Vermicompost, Nano Iron Oxide, and Humic Acid) on Grain Filling Components, Nodulation and Grain Yield of Chickpea (C... by R Seyed Sharifi, R Seyedsharifi

“…To investigate grain filling components, the first sampling was taken 14 days after podding and other samplings were taken in 5-days intervals to determine the accumulation of grain weight. The protein amount was calculated by multiplying the nitrogen content by 6.25. …”
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Diferencias de la pisada en estático después de una maratón (Differences in static footstep after a marathon) by Víctor José Fernández-Torres, Cristina Robles-Rodriguez, Guillermo De Castro-Maqueda, Victoria Candelario Poteleschenko, Jose Vicente Gutierrez-Manzanedo, Jesus Gustavo Ponce-Gonzalez

“…However, there are few biomechanical studies on footsteps, which could promote running efficiency and injuries prevention. Purpose: To determine the effects of marathon races on plantar pressure before and after a marathon race and to determine the relationship between age and plantar pressure before and after a marathon. …”
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Can the remote sensing of combustion phase improve estimates of landscape fire smoke emission rate and composition? by F. Owsley-Brown, F. Owsley-Brown, F. Owsley-Brown, M. J. Wooster, M. J. Wooster, M. J. Wooster, M. J. Grosvenor, M. J. Grosvenor, M. J. Grosvenor, Y. Liu, Y. Liu

“…We use intensively measured laboratory burns to evaluate two EO approaches hypothesized to enable remote determination of combustion phase and concurrent measurements of the smoke to determine how well each is able to improve estimation of smoke emission rates, smoke composition, and the overall rate of fuel consumption. …”
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Mediastinal lymph node dissection effectiveness in patients with I stage of non-small cell lung cancer by A. P. Kolesnik

“…It is necessary to continue the study of the relationship and the level of efficiency of lymph dissection and adjuvant chemotherapy in patients with early-stage NSCLC to determine the causes of this pattern. …”
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Development of Enzyme-Mediated Duplex Exponential Amplification Assay for Detection and Identification of <i>Meloidogyne enterolobii</i> in Field by Bingxue Sun, Bo Gao, Rongyan Wang, Shulong Chen, Xiuhua Li, Yonghao Dong, Juan Ma

“…Its unique duplex exponential amplification mechanism achieves threshold determination 10 cycles (~10 min) faster than conventional qPCR. …”
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Alpha 2 agonists for sedation to produce better outcomes from critical illness (A2B Trial): protocol for a multicentre phase 3 pragmatic clinical and cost-effectiveness randomised... by John Norrie, Stephen Morris, Daniel Francis McAuley, Bronagh Blackwood, Paul Dark, Matt P Wise, Anthony C Gordon, Kalliopi Kydonaki, Timothy Simon Walsh, David Hope, Christopher Weir, Gavin Perkins, Nazir I Lone, Benedict Creagh-Brown, Julia Boyd, Michael Reade, Richard Anthony Parker, Leanne M Aitken, Valerie J Page, Alasdair MacLullich, Cathrine A McKenzie, Alix Macdonald, Annabel Giddings, Lydia Emerson, Robert Glen

“…The alpha 2 agonists for sedation to produce better outcomes from critical illness (A2B) trial aims to determine whether clonidine or dexmedetomidine (or both) are clinically and cost-effective in MV ICU patients compared with usual care.Methods and analysis Adult ICU patients within 48 hours of starting MV, expected to require at least 24 hours further MV, are randomised in an open-label three arm trial to receive propofol (usual care) or clonidine or dexmedetomidine as primary sedative, plus analgesia according to local practice. …”
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Evaluating the sustainable cultivation of 'Fuji' apples: suitable crop load and the impact of chemical thinning agents on fruit quality and transcription by Shicong Wang, Qianying Wang, Weiyu Jiang, Yixiong Wang, Jinjiao Yan, Xuewei Li, Jiangbo Wang, Qingmei Guan, Fengwang Ma, Jing Zhang, Qianming Zheng, Yangjun Zou, Jidi Xu

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Project quality, regulation quality by Elena Mussinelli

“…Hence, it is worth reflecting on the effectiveness and efficiency of a regulatory framework that has been governing territorial, urban and building transformations in an increasingly articulated and specialised manner with a view to improving the quality and sustainability of natural and anthropic habitats. …”
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Efficacy and safety of antipsychotics in adolescents with an acute psychotic episode in relation to the activity of CYP3A and CYP2D6 isoenzymes by D. V. Ivashchenko, A. S. Osipov, E. V. Nazarova, M. A. Ovchinnikova, N. I. Buromskaya, V. V. Smirnov, P. V. Shimanov, R. V. Deitch, T. A. Fainshtein, E. N. Shagovenko, K. A. Akmalova, A. A. Kachanova, E. A. Grishina, L. M. Savchenko, Yu. S. Shevchenko, D. A. Sychev

“…The CGAS, PANSS, UKU SERS, SAS, and BARS scales were used to evaluate the efficiency and safety of the therapy on day 14. The activity of CYP3A and CYP2D6 isoenzymes was measured by determining the metabolic ratios of the concentrations of endogenous substrates of the isoenzymes and their metabolites in a morning urine sample on days 1 and 14 of the study. …”
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Optimization, Design, and Implementation of Biodiversity-Focused Fisheries Survey Stations: A Case Study of the Coastal Waters of Maoming by Yuexiu DENG, Yongheng HUANG, Jianyu DONG, Ning CHEN, Jing ZHANG, Xuefeng WANG

“…However, most research primarily focuses on optimizing either stratification or sample allocation and pays less attention to methods that simultaneously optimize both stratification and sample allocation. …”
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