SRT3025-loaded cell membrane hybrid liposomes (3025@ML) enhanced anti-tumor activity of Oxaliplatin via inhibiting pyruvate kinase M2 and fatty acid synthase by Xiaobin Wang, Shulin Li, Zichen Li, Zhuona Lin, Zhifeng Wang

“…Drug encapsulation efficiency and loading capacity were determined to investigate the advantages of the SRT3025-loaded cell membrane hybrid liposomes (3025@ML). …”
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Novel Nanozyme-Based Multicomponent in situ Hydrogels with Antibacterial, Hypoxia-Relieving and Proliferative Properties for Promoting Gastrostomy Tube Tract Maturation by Xiao F, Yan B, Yuan T, He Y, Zhang X, He X, Peng W, Xu Y, Cao J

“…However, there is currently no relevant research to promote gastrostomy wound treatment and tract maturation.Methods: Herein, a nanozyme loaded bioactive hydrogels (MO-HPA) was developed to accelerate tract maturation and inhibit bacteria. …”
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Indicators of rheumatoid arthritis disease activity. An association with a patient’s psychological status by V. V. Rybakova, Yu. A. Olyunin, E. V. Likhacheva, E. L. Nasonov

“…The findings may suggest that there is a need to assess the psychological status of a patient when determining the level of RA disease activity.…”
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STUDYING DEVELOPMENT OF POST-VACCINAL CELLULAR IMMUNITY AGAINST BRUCELLOSIS BY MEANS OF LYMPHOCYTE <i>IN VITRO</i> TESTS USING AN EXPERIMENTAL ANTIGENIC COMPLEX by M. V. Kostyuchenko, E. L. Rakitina, D. G. Ponomarenko, O. V. Logvinenko, S. A. Kurcheva, T. V. Berdnikova, D. V. Rusanova, A. N. Kulichenko

“…The applied experimental antigen is a quite promising tool for development of laboratory algorithms for brucellosis diagnostics, and assessment of actual vaccination efficiency in cohorts previously vaccinated against brucellosis.…”
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ASSESSMENT OF CITIZENS'AWARENESS REGARDING ORAL HYGIENE AND PREVENTION OF DENTAL DISEASES by L.F. Kaskova, O.S. Pavlenkova, M.O. Sadovski, L.I. Amosova

“…Two age groups were selected for the results: young and middle-aged, as these groups are the most common. Age was determined by survey. 50 people aged 25-44 years and 50 people aged 44-60 years were elected. …”
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Development and Clinical Interpretation of an Explainable AI Model for Predicting Patient Pathways in the Emergency Department: A Retrospective Study by Émilien Arnaud, Pedro Antonio Moreno-Sanchez, Mahmoud Elbattah, Christine Ammirati, Mark van Gils, Gilles Dequen, Daniel Aiham Ghazali

“…The best model was validated internally with a test set, and the F1 score was used to determine the best threshold for recall, precision, and accuracy. …”
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RESULTS OF AN OBSERVATIONAL PROSPECTIVE STUDY OF THE EFFICACY AND SAFETY OF BELIMUMAB (BENLYSTA®) IN SYSTEMIC LUPUS ERYTHEMATOSUS IN REAL CLINICAL PRACTICE by E. A. Aseeva, S. K. Soloviev, A. A. Mesnyankina, T. M. Reshetnyak, N. E. Lopatina, S. I. Glukhova, E. L. Nasonov

“…BLM was used as monthly intravenous infusions at a dose of 10 mg/kg. The efficiency and safety of the therapy were evaluated monthly and 1 year after the initiation of treatment with BLM; SLE activity was estimated using SLEDAI-2K; a physician’s global assessment of disease activity on a visual analogue scale (VAS); anti-DNA antibody level changes, complement levels, a GC dose, damage index, and adverse events were determined.Results and discussion. …”
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Modeling Marine Geoid in the China Seas and Its Adjacent Ocean Based on Satellite Altimeter-Derived Gravity Anomaly Model by Huiying Zhang, Xin Liu, Zhen Li, Xiaotao Chang, Heping Sun, Hui Li, Jinyun Guo

“…The Stokes formula is employed in this study to construct the geoid model, while the two-dimensional fast Fourier transform convolution in planar coordinate is utilized to enhance computational efficiency. Additionally, the remove-computer-restore method is applied during the calculation process. …”
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Research on Quantitative Evaluation of Defects in Ferromagnetic Materials Based on Electromagnetic Non-Destructive Testing by Xiangyi Hu, Ruijie Xie, Ruotian Wang, Jiapeng Wang, Haichao Cai, Xiaoqiang Wang, Xiang Li, Qingzhu Guan, Jianhua Zhang

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Differences in Soil Reinforcement and Root Fatigue Properties of Typical Shrubs in Semi-arid Mining Areas by Xin Zhang, Bo Wang, Tiejun Liu, Jianying Guo, Hugang Wang, Zhenqi Yang

“…[Objective] The effects of cyclic load on root tensile resistance characteristics of three typical shrubs, and the change of soil reinforcement efficiency of shrub roots after fatigue were determined in order to provide a scientific basis for plant selection in the process of ecological restoration and erosion prevention and control in semi-arid mining areas. …”
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Post-vibration activity of electrochemically activated water by O. V. Slatinskaia, G. O. Stepanov, O. V. Fartushnaya, E. V. Zubkov, A. D. Zatykina, O. M. Gizitdinova, N. S. Karpov, A. V. Smirnov, V. S. Boriskin, N. N. Rodionova, A. O. Petrova

“…Different degrees of changes in the physicochemical characteristics are observed depending on the parameters of the electric signal used to obtain the initial substance. The efficiency of electrical signal propagation in these mixtures, as estimated by the signal strength attenuation coefficient, is additionally changed. …”
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Preparation and in vitro evaluation of platelet membrane biomimetic liposomes loaded with vincristine sulfate by XIAO Jing, YOU Xunyi, ZHANG Along, ZHONG Rui, LIU Jiaxin, CAO Ye, WANG Hong

“…[Objective] To prepare platelet membrane biomimetic liposomes loaded with vincristine sulfate (VCR) for targeted delivery to tumor. [Methods] Vincristine sulfate liposomes (LIPO) were prepared using the pH-gradient method, followed by the fusion of platelet membranes and subsequent drug loading to obtain platelet membrane biomimetic liposomes (PLM-LIPO). …”
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Nose-to-Brain Delivery of Chitosan-Grafted Leciplexes for Promoting the Bioavailability and Antidepressant Efficacy of Mirtazapine: In Vitro Assessment and Animal Studies by Amani M. El Sisi, Essam M. Eissa, Ahmed H. E. Hassan, Marina A. Bekhet, Fatma I. Abo El-Ela, Eun Joo Roh, Rasha M. Kharshoum, Adel A. Ali

“…Then, the determined optimum formulation was coated with chitosan (CS-MRZ-LPX) and utilized in pharmacodynamics investigations and in vivo biologic distribution studies in Wistar male rats. …”
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New Realities of the Enterprise Management System Information Support: Economic and Mathematical Models and Cloud Technologies by Anatolii Asaul Asaul, Mykhailo Voynarenko, Liudmyla Yemchuk, Larysa Dzhulii

“…In the process of research, the sequence of construction and the overall structure of the enterprise management system, based on the use of cloud technologies, are determined, which allowed to build a mathematical model for calculating the probability of making an error-free decision, evaluating the efficiency of decision-making, a model of making a management decision for a certain time with the parallel method of operation of elements of the enterprise management system.…”
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Optimizing Goods Placement in Logistics Transportation using Machine Learning Algorithms based on Delivery Data by Moh Husnus Syawab, Yunifa Miftachul Arief, Fresy Nugroho, Ririen Kusumawati, Cahyo Crysdian, Agung Teguh Wibowo Almais

“…By doing so, they sought to determine which method delivers more accurate predictions for the optimal placement of goods. …”
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Optimization of a novel dental self-healing resin composite by bacteria-induced biomineralization by Yanyan Han, Yanyan Han, Xiaoxuan Zhang, Jianing Weng, Shiqi Tian, Xian Dong, Zhiheng Cai, Zhiheng Cai, Yi Zhang, Tiantian Wu, Tiantian Wu, Dan Lin, Yaqin Zhu, Yaqin Zhu

“…This method took a microscopic view of the healing process in artificial saliva, and the self-healing efficiency was determined by quantifying the scratch area.ResultsIn the final results, Bacillus sphaericus (ATCC 4525) cultured with Mn2+ exhibited the most impressive self-healing effect, while Bacillus pasteurii (B80469) had the weakest self-healing effect in the study. …”
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Optimal and Economic Programming in a Reconfigured Competitive Electricity Market Considering Dispersed Generation Sources with the Firefly Algorithm by Muhammad Sibtain, Snoober Saleem

“…The optimal sales prices of the units are also calculated by the game theory. The proposed method is implemented on a 33-bus system in MATLAB, and its results are compared with PSO and GA results to demonstrate the efficiency.…”
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Extraction and Analysis of Strontium in Water Sample Using a Sr2+ Selective Polymer as the Absorbent Phase by Rongjian Ying

“…Under the optimized conditions, the concentrations of Sr2+ in four water samples were detected by the developed method. We propose that this method effectively extracts strontium ion from environmental water samples.…”
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Computational Technique for Crack Propagation Simulation in Viscoelastic Solid Propellant by Qiangqiang Jiang, Xuan Lv, Huiru Cui, Teng Ma

“…Typical fracture problem, single edge-notched tension test (SENT) is solved to demonstrate the efficiency and accuracy of the proposed method. In addition, double edge-notched tension test (DENT) as well as plate tension test with a slant crack is conducted to show the special fracture characters in viscoelastic solid propellant, like time dependence. …”
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Shape optimization and mechanical properties analysis of the free-form surface by Cui Guoyong, Cui Changyu

“…A new method was established to minimize the strain energy while improving the computation efficiency. …”
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