Cumulative live births and predictive factors of emergency oocyte cryopreservation: a retrospective cohort study by Zichuan Han, Tian Tian, Nan Zhang, Jiaxiang Wang, Jia Li, Lixue Chen, Wan Yang, Ping Liu, Rong Li, Jie Qiao, Rui Yang

“…However, the infrequent and unpredictable nature of emergency oocyte cryopreservation leads to a scarcity of literature on its reproductive outcomes, complicating the provision of informed patient counseling. Methods This study, conducted between January 2017 and December 2022, included 137 emergency oocyte cryopreservation cycles involving 136 patients and their respective thawed cycles. …”
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Greater Improvements in Vaccination Outcomes Among Black Young Adults With Vaccine-Resistant Attitudes in the United States South Following a Digital Health Intervention: Latent Pr... by Noah Mancuso, Jenna Michaels, Erica N Browne, Allysha C Maragh-Bass, Jacob B Stocks, Zachary R Soberano, C Lily Bond, Ibrahim Yigit, Maria Leonora G Comello, Margo Adams Larsen, Kathryn E Muessig, Audrey Pettifor, Lisa B Hightow-Weidman, Henna Budhwani, Marie C D Stoner

“…MethodsBlack young adults aged 18‐29 years in Alabama, Georgia, and North Carolina who were unvaccinated or insufficiently vaccinated against COVID-19 completed three online surveys over three months (N=360). …”
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In Vitro Characterization of the Immune Response to an Epitope Ensemble Vaccine Against Rhinovirus in Pediatric Asthma and Adults With Chronic Obstructive Pulmonary Disease: Protoc... by Sara Alonso Fernandez, Raquel Reyes-Manzanas, Susana Camara, Juan Mozas-Gutierrez, Myriam Calle-Rubio, Juan Rodriguez-Hermosa, Andres Bodas-Pinedo, Santiago Rueda Esteban, Esther M Lafuente, Jesús Reiné, Pedro A Reche

“…MethodsParticipants with asthma and those with COPD, aged 5-15 and 40-70 years, respectively, will be recruited alongside healthy age-matched controls. …”
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PFO‐ACCESS: Augmenting Communications for Medical Care or Closure in the Evaluation of Patients With Stroke With Cardiac Shunts by Yasaman Pirahanchi, Benjamin Shifflett, Ehtisham Mahmud, Stefanie Brennan, Dawn M. Meyer, Melissa Mortin, Lovella Hailey, Jeffrey Bowers, Vikas Ravi, Julián Carrión, Reza Bavarsad, Kunal Agrawal, Royya Modir, Thomas Hemmen, Brett C. Meyer

“…Methods In this quality improvement project, we compared pre‐PFO ACCESS (December 2022–November 2023) to post‐PFO ACCESS periods (November 2023–June 2024) regarding PFO evaluations. …”
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Polyphenol-Rich Snack Consumption during Endurance Exercise Training Improves Nitric Oxide Bioavailability but does not Improve Exercise Performance in Male Cyclists: A Randomised... by Noah Marc Adrian d’Unienville, Alison M Coates, Alison M Hill, Maximillian J Nelson, Kevin Croft, Catherine Yandell, Jonathan D Buckley

“…Methods: After 1 wk of light training (LT), 96 male recreationally trained cyclists consumed 125 g of AGC or control (CON: isocaloric oat bar) daily during 2 wk of heavy training (HT) and a 2-wk taper (T). …”
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Total mixed ration enhances nutrient digestibility, blood biochemical parameters and faecal microbial diversity in horses by Hongxin Jing, Pengshun Liu, Shengchen Zheng, Ketao Cao, Xiaobin Li

“…Abstract Background Total Mixed Ration (TMR) is recognized for its balanced nutritional composition, improved feed efficiency, enhanced animal production, and stabilization of the gastrointestinal microbiome. …”
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Body composition of metabolically unhealthy normal-weight patients with aortic stenosis: a prospective cohort study by Shuangxiang Lin, Chenjia Liu, Xingfa Ding, Shuyue Wang, Jiaxing Wu, Xinhong Wang, Jianzhong Sun

“…Incremental discriminative improvement (IDI) and the C-index were used to determine the influence of hybrid parameters on the predictive efficiency of the model. …”
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Exploring Older Adults’ Perspectives and Acceptance of AI-Driven Health Technologies: Qualitative Study by Arkers Kwan Ching Wong, Jessica Hiu Toon Lee, Yue Zhao, Qi Lu, Shulan Yang, Vivian Chi Ching Hui

“… Abstract BackgroundArtificial intelligence (AI) is increasingly being applied in various health care services due to its enhanced efficiency and accuracy. As the population ages, AI-based health technologies could be a potent tool in older adults’ health care to address growing, complex, and challenging health needs. …”
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GAME AS AN ELEMENT OF HYGIENE MOTIVATION OF PRE-SCHOOLERS by V.S. Melnyk, L.F. Horzov

“… The aim of our research was to evaluate the effectiveness of a game in teaching the pre-schoolers, and the degree of learning to preserve children`s dental health. Materials and methods. 56 pre-schoolers of the Kindergarten № 6, aged 4-6, took part in our research. …”
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THE REASONS THAT LEAD TO THE REDUCTION OF THE USE OF NON-REMOVABLE PROSTHESIS DESIGNS by M.J. Nidzelskyy, N.V. Tsvetkova, S.S. Yasnogorskaya

“…The aim of the study was to establish the causes leading to a decrease in frequency of use of orthopedic constructions. Materials and methods. For qualitative research prosthetics and the term of use removable dentures which are made in prosthetic dentistry clinic Poltava regional dental clinic we analyzed indicators restore chewing efficiency in 130 patients (38 men and 92 women), who addressed the orthopedic department for 2012-2014 and who for medical reasons have been removed fixed constructions. …”
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Innovative machine learning-based prediction of early airway hyperresponsiveness using baseline pulmonary function parameters by Hua Yang, Xingru Zhao, Zhuochang Chen, Lihong Yang, Guihua Zhao, Chenxiao Xu, Jinyi Xu

“…This study explores the potential of baseline pulmonary function parameters, particularly small airway indices, in predicting AHR and develops a machine learning-based model to improve screening efficiency and reduce unnecessary BPT referrals.MethodsThis retrospective study analyzed baseline pulmonary function data and BPT results from Henan Provincial People’s Hospital (May to September 2024). …”
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A bayesian network model for neurocognitive disorders digital screening in Chinese population: development and validation study by Yifan Yu, Shuaijie Zhang, Hongkai Li, Fuzhong Xue

“…Therefore, there is an urgent need to develop an inexpensive and convenient screening model for neurocognitive disorders that can be applied to large populations to improve the efficiency of neurocognitive disorders screening. Methods This study aimed to construct a classification model for screening neurocognitive disorders (NCDs) based on cross-sectional electronic health record data from the Cheeloo Whole Lifecycle eHealth Research-based Database (2015–2017). …”
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Viral characterization of the reassortants between canine influenza H3N2 and human pandemic (2009) H1N1 and avian H9N2 viruses in canine ex vivo tracheal explants by Tonia T. Kam, Christine H. T. Bui, Hin-Wo Yeung, Peter C. H. Wong, Alex W. H. Chin, John M. Nicholls, Malik Peiris, Kenrie P. Y. Hui, Leo L. M. Poon, Michael C. W. Chan

“…The resulting reassortants were plaque-purified and inoculated in human alveolar epithelial cells to determine their replication competence and proinflammatory cytokine induction profile. …”
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Alpha 2 agonists for sedation to produce better outcomes from critical illness (A2B Trial): protocol for a multicentre phase 3 pragmatic clinical and cost-effectiveness randomised... by John Norrie, Stephen Morris, Daniel Francis McAuley, Bronagh Blackwood, Paul Dark, Matt P Wise, Anthony C Gordon, Kalliopi Kydonaki, Timothy Simon Walsh, David Hope, Christopher Weir, Gavin Perkins, Nazir I Lone, Benedict Creagh-Brown, Julia Boyd, Michael Reade, Richard Anthony Parker, Leanne M Aitken, Valerie J Page, Alasdair MacLullich, Cathrine A McKenzie, Alix Macdonald, Annabel Giddings, Lydia Emerson, Robert Glen

“…The alpha 2 agonists for sedation to produce better outcomes from critical illness (A2B) trial aims to determine whether clonidine or dexmedetomidine (or both) are clinically and cost-effective in MV ICU patients compared with usual care.Methods and analysis Adult ICU patients within 48 hours of starting MV, expected to require at least 24 hours further MV, are randomised in an open-label three arm trial to receive propofol (usual care) or clonidine or dexmedetomidine as primary sedative, plus analgesia according to local practice. …”
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The effect of tofacitinib on function and quality of life indicators in patients with rheumatoid arthritis resistant to synthetic and biological disease-modifying antirheumatic dru... by D. E. Karateev, D. E. Abdulganieva, A. R. Babaeva, A. A. Baranov, L. P. Evstigneeva, O. N. Ivanova, G. V. Lukina, E. L. Luchikhina, V. I. Mazurov, A. S. Misiyuk, O. V. Semagina, A. E. Sizikov, V. N. Sorotskaya

“…Tofacitinib (TOFA), a representative of a new class of targeted synthetic disease-modifying antirheumatic drugs (s-DMARD), is a promising drug for treating rheumatoid arthritis (RA) and other immune inflammatory diseases.Objective: to evaluate the efficiency and safety of therapy with TOFA in combination with methotrexate (MTX) and other s-DMARDs in real clinical practice in patients with active RA and previous ineffective therapy.Patients and methods. …”
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Identification and validation of reference genes for qPCR of Pseudomonas aeruginosa L10 under varying n-hexadecane concentrations by Huan Wang, Xiaobing Wang, Juntao Chen, Yumiao Zhang, Junhua Liu, Fangliang Xia, Jian Li, Tao Wu, Longxiang Liu

“…Abstract Pseudomonas aeruginosa can efficiently degrades petroleum hydrocarbons, but its degradation rate is affected by hydrocarbon pollutant concentrations, which must be neither too high nor too low. …”
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The diagnostic of PAX1 gene methylation in cervical lesions and its role in the triage of non-16/18 HR-HPV positive by Meng-Meng Chen, Meng-Meng Chen, Bing-Qiang Zhang, Bing-Qiang Zhang, Yan-Song Luan, Guo-Long Sun, Yun-Yuan Zhang, Xiao-Yan Zhou, Xi-Feng Zhang, Feng-Chun Gao, Jun-Mei Yu

“…PAX1 gene methylation detection employed fluorescence quantitative PCR technology with ACTB as the internal reference gene, determining methylation levels through calculation of ΔCT values. …”
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Ending preventable maternal deaths in Malawi: the stakeholders consensus approach to identify maternal health needs priorities by Mtisunge Joshua Gondwe, Leonard Mndala, Chifundo Kondoni, Annie Kuyere Khumalo, Bertha Maseko, Laura Munthali, Catherine Bamuya, Rosemary Bilesi, Henry Phiri, Fannie Kachale, Malangizo Mbewe, Jennifer Riches, Maria Lisa Odland, Effie Chipeta, Elizabeth Chodzaza, David Lissauer, Alinane Linda Nyondo-Mipando

“…Priority setting is a crucial concept that can benefit the healthcare system in Malawi by efficiently distributing limited resources and maximising gains in maternal healthcare. …”
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Poisoning Epidemiology, Clinical Outcomes and Management Decisions for General Public Calls: A Cross-Sectional Analysis of a Nationwide Telehealth Toxicology Consultation Service D... by Abdullah A. Alharbi, Mohammed A. Muaddi, Meshary S. Binhotan, Ahmad Y. Alqassim, Ali K. Alsultan, Mohammed S. Arafat, Abdulrahman Aldhabib, Yasser A. Alaska, Eid B. Alwahbi, Meshari A. Almutairi, Mobarak Alharthi, M. Mahmud Khan, Mohammed Alabdulaali, Nawfal A. Aljerian

“…Methods We conducted a retrospective analysis of all public calls to the national TCS hotline between January 1 and December 31, 2023. …”
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Fistula Tract Laser Closure (FiLac) versus Standard Fistulectomy in the Treatment of Simple Perianal Fistula: A Prospective Interventional Study by Shreethi Sasidharan Pillai, D Balaji, Harshwanth Chandhar, G Tilak Ramu, K Shanmugapriya

“…Conclusion: FiLaC demonstrates advantages over standard fistulectomy in terms of efficiency, recovery time, and complication rates for treating simple perianal fistulas. …”
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