RNF31 induces paclitaxel resistance by sustaining ALYREF cytoplasmic–nuclear shuttling in human triple‐negative breast cancer by Shumei Huang, Dongni Shi, Shuqin Dai, Xingyu Jiang, Rui Wang, Muwen Yang, Boyu Chen, Xuwei Chen, Lingzhi Kong, Lixin He, Pinwei Deng, Xiangfu Chen, Chuyong Lin, Yue Li, Jun Li, Libing Song, Yawei Shi, Weidong Wei

“…Methods The subcellular proportion of ALYREF was detected in samples from patients with TNBC using immunohistochemistry to analyze the relationship between ALYREF distribution and paclitaxel response. …”
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IL-19 as a promising theranostic target to reprogram the glioblastoma immunosuppressive microenvironment by Gilbert Aaron Lee, Justin Bo-Kai Hsu, Yu-Wei Chang, Li-Chun Hsieh, Yi-Tien Li, Ying Chieh Wu, Cheng-Ying Chu, Yung-Hsiao Chiang, Wan-Yuo Guo, Chih-Chun Wu, Liang-Wei Chen, Hung-Wen Kao, Wan-Li Lin, Li‑Wen Tseng, Ting-Wei Weng, Duen-Pang Kuo, Sho-Jen Cheng, Yung-Chieh Chen, Shiu-Wen Huang, Hsing-Jien Kung, Cheng-Yu Chen

“…Targeting GBM-mediated immunosuppressive and invasive properties is a promising strategy to improve clinical outcomes. Methods We utilized clinical and genomic data from the Taiwan GBM cohort and The Cancer Genome Atlas (TCGA) to analyze RNA sequencing data from patient tumor samples, determining the association of interleukin-19 (Il-19) expression with survival and immunosuppressive activity. …”
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Unlocking data: Decision-maker perspectives on cross-sectoral data sharing and linkage as part of a whole-systems approach to public health policy and practice by Emily Tweed, Kristina Cimova, Peter Craig, Mirjam Allik, Denise Brown, Mhairi Campbell, David Henderson, Charlie Mayor, Petra Meier, Nick Watson

“…Aim We sought to work collaboratively with decision-makers relevant to healthy public policy and practice in Scotland to identify practical ways that cross-sectoral data sharing and linkage could be used to best effect to improve health and reduce health inequalities. Methods We facilitated three sequential stakeholder workshops with 20 participants from local and central government, public health teams, Health and Social Care Partnerships, the third sector, organisations which support data-intensive research and public representatives from across Scotland. …”
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Mechanism of exogenous methyl jasmonate mediated AsA-GSH cycle in Summer Black grape against low temperature stress by ZHANG Shaowei, ZHU Qianyan, ZHAO Xiaogai, ZHOU Bing, LI Peng, LI Guirong

“…[Objective] The aim of this study was to explore the response mechanism of the exogenous Methyl jasmonate (MeJA) regulating the ascorbic acid-glutathione (AsA-GSH) cycle of Vitis vinifera Summer Black grape to low-temperature stress. [Methods] One-year-old Summer Black grape plants were used as materials, and different concentrations of MeJA treatment groups and low-temperature stress treatment groups were set up. (1) MeJA treatment: the selected 1-year-old Summer Black grape plants were randomly divided into 5 groups, with 10 plants in each group.0 (CK), 50, 100, 150, 200 μmol·L-1 MeJA solution were sprayed on the leaves, and the spraying amount was suitable for the uniform wetting of the leaf surface without water dripping. …”
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Implementation of the mini-CEX in a paediatric emergency department by Iris Alonso Sánchez, Sandra Morán Moya, Gemma Claret Teruel, Roser Garrido Romero, David Muñoz Santanach, Victoria Trenchs Sainz de la Maza, Carles Luaces Cubells

“…Material and methods: Inclusion criteria: paediatrics residents in the first (MIR1) and second (MIR2) year of residency. …”
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Rheumatoid arthritis in real clinical practice: initiation of therapy with biological agents. Results of the «Computer Terminals of Self-Assessment for Patients with Rheumatic Dise... by V. N. Amirdzhanova, E. Yu. Pogozheva, A. E. Karateev, O. V. Antipova, I. B. Vinogradova, A. Yu. Kazankova, R. G. Mukhina, A. G. Vasilyev, O. B. Nesmeyanova, E. A. Bogdanova, R. R. Samigullina, A. A. Vasilenko, I. B. Bashkova, T. S. Salnikova, I. N. Dashkov, N. E. Nikulenkova, V. Yu. Manokhin, I. P. Afanasyeva, O. N. Anoshenkova, T. V. Plaksina, M. R. Spitsina, L. V. Solodovnikova, A. V. Petrov, O. P. Slyusar, E. V. Papichev, E. V. Ivanova, L. V. Masneva, L. P. Evstigneeva, I. V. Kolotilina, E. N. Otteva, I. A. Cherentsova, I. N. Shchendrygin, S. A. Derevenskikh, I. G. Bannikova, N. K. Delyavskaya, I. N. Danilova, I. M. Marusenko

“…Objective: to assess quality-of-life (QoL) dynamics in patients with rheumatoid arthritis (RA) when initiating therapy with biological agents (BAs) in real clinical practice.Patients and methods. The investigation enrolled patients with RA from the patient cohort participating in the TERMINAL-II multicenter Russian study, who newly initiated BA therapy. …”
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Stability of developing oil companies of Russia by V. V. Biryukova

“…In the article the questions of stability of developing Russian companies of an oil and gas complex are considered; methodological and methodical approaches to the analysis of stability of the oil companies as difficult, open spontaneous social and economic systems are stated; results of the stability assessment of their development on the basis of determining indexes of economic efficiency, ecological and social responsibility, and also innovative activity are presented.…”
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Development Level Evaluation of Tax Governance Digitalization Using Quadripartitioned Single-Valued Neutrosophic Sets by Shuguang Wang, Renjie Bao

“…A key component of improving the accountability, efficiency, and openness of public financial institutions is the digital transformation of tax governance. …”
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Addressing Shortcomings in Contingency Standards of Care by Alexander Quan

“…Without a formal system to guide the process or transition from the usual method of allocation to the contingency period, contingency decisions about who gets a scarce resource may continue to operate on an implicit FCFS basis, even when approaching crisis levels of scarcity. …”
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ALGORITHM DEVELOPMENT FOR ASSESSMENT OF ACCURACY POSITIONING SYSTEMS GLONASS/GPS WITH DIFFERENTIATED APPLICATION OF FERTILIZERS by G. I. Lichman, V. A. Kolesnikova, N. M. Marchenko, A. N. Marchenko

“…One of the directions of increase in fertilizers efficiency is reduction of nonuniformity of their distribution across the field. …”
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The results of the analysis of the research-methodological functions of the test current control of knowledge for natural sciences in MGRI by E. S. Gaponenko, V. N. Komarov

“…It has confirmed that the test system of the current control allowed carrying out effective diagnostics of higher education, making more systematic and effective carrying out of lessons, organization of the self-control over the digestion of some topics of the course and correction lecture material in order to increase the efficiency of the training. The consequence of methodically correct organization of systematic test control is the formation of holistic natural science world view by students, as well as the culture of educational process by students — concentration, responsibility, accuracy, ability to develop internal and external self-organization and self-control. …”
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L’ESTHÉTIQUE LITTÉRAIRE ORALE, POUR UNE APPROCHE AFRICAINE D’UN ÉNONCE SENTENCIEUX GULMANCE by Yendifimba Dieudonné LOUARI

“…L’objectif de cet article est de revisiter cette nouvelle approche et d’en déterminer son efficience quant à la lecture du discours oral africain. …”
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Technology of automated video observation of a drogue-sensor basket in the problem of autonomous aerial refueling by A. V. Gaidenkov, M. I. Kanevskiy, A. S. Ostrovskiy, O. I. Ganyak, N. Yu. Chizhov

“…The technology is based on the use of a passive optoelectronic system and incorporates the logic of automated refueling observation of a refueling process using algorithms for the automatic detection and tracking of a drogue-sensor, a methodical apparatus for suboptimal linear filtering of the observed process under the conditions of spatial and temporary non-stationarity of the refueling process, algorithms for automatic correlation detection and tracking of a drogue-sensor using suboptimal filtering. …”
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Comparative Ethics of Modern Payment Models by Jacob Riegler

“…Volume-based reimbursement schemes prioritize efficiency, regardless of these major bioethical principles. …”
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Comparative Ethics of Modern Payment Models by Jacob Riegler

“…Volume-based reimbursement schemes prioritize efficiency, regardless of these major bioethical principles. …”
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L’élevage de ruminants s’adaptera-t-il au changement climatique ? Impacts et leviers d’adaptation by Aurélie MADRID, Renée DE CRÉMOUX, Luc DELABY, Hélène LARROQUE, Sandra NOVAK, Aurélie VINET

“…Des méthodes et outils existent pour aider les éleveurs à déterminer les leviers les plus adaptés à leur système, et pour les accompagner dans la construction d’une stratégie d’adaptation les combinant au mieux. …”
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