A bayesian network model for neurocognitive disorders digital screening in Chinese population: development and validation study by Yifan Yu, Shuaijie Zhang, Hongkai Li, Fuzhong Xue

“…Therefore, there is an urgent need to develop an inexpensive and convenient screening model for neurocognitive disorders that can be applied to large populations to improve the efficiency of neurocognitive disorders screening. Methods This study aimed to construct a classification model for screening neurocognitive disorders (NCDs) based on cross-sectional electronic health record data from the Cheeloo Whole Lifecycle eHealth Research-based Database (2015–2017). …”
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Spectroscopic analysis (UV-VIS-NIR) for predictive modeling of macro and micronutrients in grapevine leaves by J.I. Manzano, M. Rodríguez-Febereiro, M. Fandiño, M. Vilanova, J.J. Cancela

“…Diffuse reflectance spectroscopy coupled with chemometric methods emerges as a potent, cost-effective, and environmentally friendly analytical technique for determining nutrient concentrations in plants. …”
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The evaluation of equipment remote operation and pyroprocessing verification in hot cell by NIU Yongsheng, SUN Lixin, WANG Baozhu, ZHANG Han, FU Haiying, DOU Qiang, ZHOU Wei, QIAN Yuan, LI Qingnuan

“…The hot cell is an important guarantee for the practical application of nuclear fuel reprocessing technology, therefore, a remote operation system suitable for reprocessing post-treatment process equipment is developed so that the pyroprocessing experiments of molten salt can be conducted in hot cell.PurposeThis study aims to evaluate equipment remote operation and pyroprocessing verification in hot cell.MethodsMain focus of this study was the fluoride volatility and vacuum distillation process of molten salt reactor fuel salts, and the remote operation evaluation of hot cell equipments and pyroprocessing verification experiments were carried out using multi-view coordination. …”
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Rootstock impacts on ‘USDA-ARS-Pawnee’ pecan growth, physiological traits, and soil microbial communities by Xinwang Wang, Keith Kubenka, Warren Chatwin, Angelyn Hilton, Braden Tondre, Tingying Xu, Lu Zhang

“…Twelve distinct rootstocks were evaluated to determine their influence on scion development. Measurements of photosynthesis rate (PSR) and water use efficiency (WUE) were collected to establish correlations with leaf size. …”
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Sequential therapy with rituximab and belimumab in patients with systemic lupus erythematosus by A. A. Mesnyankina, S. K. Solovyev, N. Yu. Nikishina, E. A. Aseeva, N. V. Demidova, E. L. Nasonov

“…Objective: to determine the efficiency of sequential (combined) therapy with rituximab (RTM) and belimumab (BLM) in patients with active systemic lupus erythematosus (SLE).Patients and methods. …”
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Patient Burden And Impact Of Moderate-to-Severe Atopic Dermatitis In the Spanish Healthcare System: The APOLO Cross-Sectional Study by Pablo De La Cueva Dobao, Laia Curto Barredo, Juan Francisco Silvestre Salvador, Esther Serra Baldrich, Pedro Herranz Pinto, Natalia Hernández Cano, Francisco Javier Ortiz De Frutos, Gastón Roustan Gullón, Rosa María Izu Belloso, Irene Arévalo Ortega, Alicia González Quesada, Manuel Galán Gutiérrez, Yolanda Gilaberte Calzada, Daniel Arumi Torredemer, Noelia Llevat Felius, Irene Hernández Martín, Francisco José Rebollo Laserna

“…Methods: The APOLO is a multicenter, descriptive, cross-sectional study conducted at 12 Spanish sites, in which participants completed a series of scales and questionnaires. …”
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AI-assisted diagnosis of vulvovaginal candidiasis using cascaded neural networks by Zhongxiao Wang, Ruliang Wang, Haichun Guo, Qiannan Zhao, Huijun Ren, Jumin Niu, Ying Wang, Wei Wu, Bingbing Liang, Xin Yi, Xiaolei Zhang, Shiqi Xu, Xianling Dong, Liqun Wang, Qinping Liao

“…Timely and accurate diagnosis is crucial. Traditional methods, relying on clinical evaluation and manual microscopic examination, have limitations. …”
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Viral characterization of the reassortants between canine influenza H3N2 and human pandemic (2009) H1N1 and avian H9N2 viruses in canine ex vivo tracheal explants by Tonia T. Kam, Christine H. T. Bui, Hin-Wo Yeung, Peter C. H. Wong, Alex W. H. Chin, John M. Nicholls, Malik Peiris, Kenrie P. Y. Hui, Leo L. M. Poon, Michael C. W. Chan

“…Given that the canine respiratory tract is susceptible to a wide range of influenza viruses, it is of interest whether H3N2-CIV are likely to reassort with human and avian IAVs to generate reassortants with increased zoonotic potential. Methods We conducted a co-infection study in canine tracheal explants. …”
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Profiling of driver mutations in lung adenocarcinoma patients identifies rare compound EGFR mutations sensitive to second-generation EGFR-TKIs by Jun Li, Cuiyun Zhang, Yuping Guan, Siyu Wang, Jiawen Zheng, Junnan Feng, Sile Han, Ruijuan Ma, Pengfei Ren, Shasha Li, Harry J. M. Groen, Klaas Kok, Anke van den Berg, Bing Wei, Jie Ma, Hongle Li, Yongjun Guo

“…Material and methods Targeted sequencing covering the hotspot regions of eight LUAD driver genes was performed across 853 treatment-naive LUAD patients admitted in Henan Cancer Hospital (HNCH cohort). …”
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The effect of tofacitinib on function and quality of life indicators in patients with rheumatoid arthritis resistant to synthetic and biological disease-modifying antirheumatic dru... by D. E. Karateev, D. E. Abdulganieva, A. R. Babaeva, A. A. Baranov, L. P. Evstigneeva, O. N. Ivanova, G. V. Lukina, E. L. Luchikhina, V. I. Mazurov, A. S. Misiyuk, O. V. Semagina, A. E. Sizikov, V. N. Sorotskaya

“…Tofacitinib (TOFA), a representative of a new class of targeted synthetic disease-modifying antirheumatic drugs (s-DMARD), is a promising drug for treating rheumatoid arthritis (RA) and other immune inflammatory diseases.Objective: to evaluate the efficiency and safety of therapy with TOFA in combination with methotrexate (MTX) and other s-DMARDs in real clinical practice in patients with active RA and previous ineffective therapy.Patients and methods. …”
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Identification and validation of reference genes for qPCR of Pseudomonas aeruginosa L10 under varying n-hexadecane concentrations by Huan Wang, Xiaobing Wang, Juntao Chen, Yumiao Zhang, Junhua Liu, Fangliang Xia, Jian Li, Tao Wu, Longxiang Liu

“…Abstract Pseudomonas aeruginosa can efficiently degrades petroleum hydrocarbons, but its degradation rate is affected by hydrocarbon pollutant concentrations, which must be neither too high nor too low. …”
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The diagnostic of PAX1 gene methylation in cervical lesions and its role in the triage of non-16/18 HR-HPV positive by Meng-Meng Chen, Meng-Meng Chen, Bing-Qiang Zhang, Bing-Qiang Zhang, Yan-Song Luan, Guo-Long Sun, Yun-Yuan Zhang, Xiao-Yan Zhou, Xi-Feng Zhang, Feng-Chun Gao, Jun-Mei Yu

“…ObjectiveThis study aims to systematically evaluate the application value of PAX1 gene methylation detection in cervical lesion screening and its potential advantages in the triage of non-16/18 high-risk human papillomavirus (HR-HPV) positive patients.Materials and methodsThis study enrolled 1,619 HPV-positive female patients who visited the Affiliated Hospital of Qingdao University from December 2023 to March 2025, with 989 patients ultimately meeting the inclusion criteria. …”
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Ending preventable maternal deaths in Malawi: the stakeholders consensus approach to identify maternal health needs priorities by Mtisunge Joshua Gondwe, Leonard Mndala, Chifundo Kondoni, Annie Kuyere Khumalo, Bertha Maseko, Laura Munthali, Catherine Bamuya, Rosemary Bilesi, Henry Phiri, Fannie Kachale, Malangizo Mbewe, Jennifer Riches, Maria Lisa Odland, Effie Chipeta, Elizabeth Chodzaza, David Lissauer, Alinane Linda Nyondo-Mipando

“…We undertook a national maternal health prioritisation exercise involving key stakeholders to enhance delivery of maternal care in Malawi. Methods During group discussions, the Nominal Group Technique was adapted to facilitate consensus on priorities after data and real-life experiences from service users were presented. …”
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Poisoning Epidemiology, Clinical Outcomes and Management Decisions for General Public Calls: A Cross-Sectional Analysis of a Nationwide Telehealth Toxicology Consultation Service D... by Abdullah A. Alharbi, Mohammed A. Muaddi, Meshary S. Binhotan, Ahmad Y. Alqassim, Ali K. Alsultan, Mohammed S. Arafat, Abdulrahman Aldhabib, Yasser A. Alaska, Eid B. Alwahbi, Meshari A. Almutairi, Mobarak Alharthi, M. Mahmud Khan, Mohammed Alabdulaali, Nawfal A. Aljerian

“…Methods We conducted a retrospective analysis of all public calls to the national TCS hotline between January 1 and December 31, 2023. …”
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Fistula Tract Laser Closure (FiLac) versus Standard Fistulectomy in the Treatment of Simple Perianal Fistula: A Prospective Interventional Study by Shreethi Sasidharan Pillai, D Balaji, Harshwanth Chandhar, G Tilak Ramu, K Shanmugapriya

“…Aim: To compare short-term (postoperative pain, bleeding, mean hospital stay) and intermediate-term (wound healing) outcomes between FiLaC and standard fistulectomy in the treatment of simple perianal fistulas. Materials and Methods: A prospective interventional study was conducted at SRM Medical College Hospital and Research Centre, Chengalpettu, Tamil Nadu, India, in the Department of General Surgery over a period of 18 months, involving 108 patients randomised into FiLaC (group A) and standard fistulectomy (group B). …”
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Dynamics of Kidney Function in Patients with Chronic Kidney Disease and Atrial Fibrillation Who Receive Dabigatran by N. A. Novikova, Z. K. Salpagarova, M. I. Chashkina, A. A. Bykova, Z. A. Alimova, А. S. Yadykina, D. F. Mesitskaya, N. A. Babakova, D. A. Andreev

“…Currently, there are scarce studies into the use of direct oral anticoagulants in patients with atrial fibrillation and chronic kidney disease (in case of Glomerular Filtration Rate (GFR) below 45 ml/min/1.73 m2).Aim. To determine the dynamics of GFR in patients with AF and CKD (in case of GFR below 45 ml/min/1.73 m2).Material and Methods. …”
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Strategy for prophylactic application of peripheral va-ecmo in transplantation involving expected extremely prolonged ischemia time by V. N. Poptsov, V. M. Zakharevich, E. A. Spirina, A. I. Skokova, A. K. Solodovnikova, A. S. Ignatkina, A. A. Kuznetsova, G. B. Glinkin

“…Materials and methods. Thirty-eight recipients (33 (86.8%) males and 5 (13.2%) females), age 11–66 (44.7 ± 12.0) years (median 48.0 years) were examined. …”
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Effectiveness of biomarker-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection: the BATCH RCT by Cherry-Ann Waldron, Philip Pallmann, Simon Schoenbuchner, Debbie Harris, Lucy Brookes-Howell, Céu Mateus, Jolanta Bernatoniene, Katrina Cathie, Saul N Faust, Josie Henley, Lucy Hinds, Kerry Hood, Chao Huang, Sarah Jones, Sarah Kotecha, Sarah Milosevic, Helen Nabwera, Sanjay Patel, Stéphane Paulus, Colin VE Powell, Jenny Preston, Huasheng Xiang, Emma Thomas-Jones, Enitan D Carrol

“…To provide detailed understanding of parent and health professionals’ attitudes to, and experiences of, participating in the BATCH RCT. Methods A pragmatic, multicentre, open-label, parallel two-arm, individually RCT conducted in 15 hospitals in the UK. …”
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Freehand ventricular catheter placement in ventriculoperitoneal shunt surgery is associated with higher rates of proximal catheter failure compared to image guidance by Nikhil Sharma, Jeffery R. Head, Regan M. Shanahan, Shovan Bhatia, Michael R. Kann, Sydney Scanlon, Amogh Vellore, Michael Raver, Hussam Abou-Al-Shaar, Nicolas M. Kass, Fritz Steuer, Lucille Cheng, Stephen P. Canton, Arka N. Mallela, Peter C. Gerszten, Edward G. Andrews

“…Methods: We conducted a retrospective review of all consecutive adult VPS procedures performed at a single hospital during a two-year period. …”
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La gestion de l’eau à Bibracte (Saône-et-Loire), avant et après la Conquête romaine by Laetitia Borau

“…Thanks to the present study it can be assumed that in Bibracte there were specific construction methods used for the hydraulic structures corresponding to local, i.e. …”
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