Subcellular mass spectrometric detection unveils hyperglycemic memory in the diabetic heart by Jiabing Zhan, Yufei Zhou, Yifan Chen, Kunying Jin, Zhaoyang Chen, Chen Chen, Huaping Li, Dao Wen Wang

“…The present study tried to investigate whether the dysregulated proteins/biological pathways, which persistently altered in diabetic hearts during normoglycemia, participate in the hyperglycemic memory. Methods Hearts of streptozotocin‐induced diabetic mice, with or without intensive glycemic control using slow‐release insulin implants, were collected. …”
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Administrative Barriers to the Development of Small and Medium-Sized Businesses in the Republic of Mordovia: Materials of Practical Research by M. V. Bikeeva, V. A. Inshakov, I. M. Fadeeva

“…In this regard, there is a need for a statistical assessment of the conditions for doing business at the regional level for the subsequent determination of directions for increasing the efficiency and effectiveness of the activities of state (municipal) authorities and identifying reserves for improving the business environment.Materials and methods. …”
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Short Term Analysis of New Single-Piece Aspheric Diffractive Trifocal Intraocular Lens Implantation by K. B. Pershin, N. F. Pashinova, M. M. Konovalova, A. Yu. Tsygankov, M. E. Konovalov, N. E. Temirov

“…Evaluation of short-term (up to 9 months) results of new one-piece aspherical diffractive trifocal intraocular lens implantation. Patients and Methods. A prospective, open-label study included 65 patients (100 eyes) with presbyopia, who received cataract extraction with the implantation of a new IOL AcrySof PanOptix® trifocal. …”
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Effects of Legume–Grass Mixture Combinations and Planting Ratios on Forage Productivity and Nutritional Quality in Typical Sand-Fixing Vegetation Areas of the Mu Us Sandy Land by Yuqing Mi, Hongbin Xu, Lei Zhang, Ruihua Pan, Shengnan Zhang, Haiyan Gao, Haibing Wang, Chunying Wang

“…Monoculture and legume–grass mixed cropping are the two most common planting methods, with mixed cropping generally demonstrating higher hay yield and superior nutritional quality compared to monoculture. …”
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Value Propositions for Digital Shared Medication Plans to Boost Patient–Health Care Professional Partnerships: Co-Design Study by Benjamin Bugnon, Francesca Bosisio, Alain Kaufmann, Pascal Bonnabry, Antoine Geissbuhler, Christian von Plessen

“…MethodsWe used an experience-based co-design approach in the French-speaking region of Switzerland. …”
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Genomic analyses revealed low genetic variation in the intron-exon boundary of the doublesex gene within the natural populations of An. gambiae s.l. in Burkina Faso by Mahamadi Kientega, Ioanna Morianou, Nouhoun Traoré, Nace Kranjc, Honorine Kaboré, Odette N Zongo, Abdoul-Azize Millogo, Patric Stephane Epopa, Franck A. Yao, Adrien M G Belem, Austin Burt, Abdoulaye Diabaté

“…Conclusion These findings will guide the implementation of doublesex-targeted gene drives to support the current control tools in malaria elimination efforts. Our methods can be applied to efficiently monitor the evolution of any sequence of interest in a natural population via pooled amplicon sequencing, surpassing the need for WGS.…”
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Evaluating the effectiveness of handheld ultrasound in primary blast lung injury: a comprehensive study by Shifeng Shao, Zhengbin Wu, Jun Liu, Zhikang Liao, Yuan Yao, Liang Zhang, Yaoli Wang, Hui Zhao

“…Primary blast lung injury (PBLI) is associated with high morbidity and mortality rates, while early diagnostic methods are limited. With advancements in medical technology, and portable handheld ultrasound devices, the efficacy of ultrasound in detecting occult lung injuries early remains unclear. …”
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SerpinA5 Inhibits Malignant Biological Behavior of Esophageal Squamous Cell Carcinoma by Regulating Fn/Integrin-β1 Signaling Pathway by Yu WEI, Zhouhua ZHANG, Zhifang LI, Li ZHANG

“…ObjectiveTo investigate the effect of SerpinA5 on the malignant biological behavior of esophageal squamous cell carcinoma (ESCC) and its molecular mechanism. MethodsThe expression levels of the SerpinA5 gene in various tumors and adjacent normal tissues were analyzed by using the TIMER2.0 database. …”
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Clinical Efficacy of a Position-Responding Mandibular Advancement Device in Patients With Obstructive Sleep Apnea by Sung-Woon On, Dong-Kyu Kim, Min Hyuk Lee, Ji Hae Lee, Kyung Chul Lee, Soo-Hwan Byun, Seok Jin Hong

“…Methods. Fourteen patients diagnosed with OSA participated in this study. …”
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Comparative study of the efficacy and safety of Chondroguard® during its combined (intra-articular and intramuscular) and intramuscular injection in patients with knee osteoarthrit... by L. I. Alekseeva, E. P. Sharapova, N. G. Kashevarova, E. A. Taskina, A. M. Lila, A. N. Bogdanov, S. A. Bozhkova, A. A. Bagretsova, S. M. Noskov, E. A. Grunina

“…All the patients were prescribed nonsteroidal anti-inflammatory drugs (NSAIDs), such as meloxicam 15 mg. To determine the efficiency of treatment, the investigators estimated the following parameters: pain intensity on a visual analogue scale (VAS), the total WOMAC index and its components (pain, stiffness, and functional insufficiency), sensory and affective-emotional pain characteristics (for the target joint) according to McGill Pain Questionnaire (MPQ) scores. …”
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Comparative assessment of primary and paraneoplastic gout in lung cancer by O. V. Syniachenko, Yu. V. Dumanskyi, Ye. D. Yehudina, O. Ye. Chernyshova, P. A. Stepko, D. M. Fedorov

“…The objective of the study: to compare the clinical and laboratory course of primary gout and disease in the LC patients compared with the tumor process clinical course in the other signs of PNPS presence and to identify risk factors. Materials and methods. 113 patients with gout (97 men and 16 women aged 33 to 79 years) were observed. …”
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Fracture identification and 3D reconstruction of coal-rock combinations based on VRA-UNet network by Dengke WANG, Longhang WANG, Yaguang QIN, Le WEI, Tanggen CAO, Wenrui LI, Lu LI, Xu CHEN, Yuling XIA

“…In the 3D reconstruction of coal-rock combinations fractures, in response to the problem that traditional threshold segmentation methods cannot accurately determine the threshold size between coal and rock, resulting in poor fracture segmentation performance, a new VRA-UNet coal-rock combinations fracture identification model based on deep learning theory is proposed, providing an optimized solution for accurate identification of coal-rock combinations fractures. …”
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Ecological adaptability of rice cultivars with different types under the low temperature and weak sunshine condition by LI Min, LUO Deqiang, JIANG Xuehai, ZHOU Weijia, GI Guangmei, WANG Xuehong, LI Shuxing

“…The root bleeding intensity of ecology-adaptive cultivars achieved 20.2 kg/(h·667m²) at the heading stage and 4.55 kg/(h·667 m²) at the maturity stage, which were 8.8% and 21.6% lower than that in the ecology-adaptive cultivars, respectively.According to the results, a strategy to increase the grain yield of the ecology-adaptive cultivars is suggested: keeping a higher filled grain ratio and a higher 1 000-grain mass, which are able to be accomplished by increasing nitrogen accumulation during the growth period from heading to maturity. Moreover, these methods such as cultivating strong roots and improving root activity are helpful to increase the amount of nitrogen absorption.…”
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Is the Hip Keeping the Ankle Out of Work after Total Ankle Arthroplasty? by Frank DiLiberto PT, PhD, Maxine Olson MS, Finola Summerville, Stacey Meardon PhD, PT, Anand Vora MD

“…Methods: Ten people after TAA (69.6±8.6 years, 5 female, 45.4±9.2 months post TAA) and five healthy control participants (66.8±8.3 years, 2 female) have completed this ongoing case-control study. …”
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Modelos matemáticos para a secagem intermitente de arroz em casca Mathematical models for intermittent drying of rice by Volnei L. Meneghetti, Elvio Aosani, Jeferson C. da Rocha, Maurício de Oliveira, Moacir C. Elias, Ricardo S. Pohndorf

“…For the adjustments of the mathematical models, a non linear regression analysis through the Simplex and Quasi-Newton methods was carried out. The values of the parameters of the models being estimated in function of the temperature of the drying air. …”
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Reproductive impacts and disease burden of metritis and placental retention in dairy cows: A longitudinal monitoring study in Southern Vietnam (2022–2024) by Thuong Thi Nguyen, Lien Thi Bich Nguyen, Khang Nguyen Duong, Thuan Khanh Nguyen

“…Materials and Methods: A longitudinal study was conducted on a dairy herd monitored through skin conductance responses activity sensors and DataFlow™ II software (Allflex Livestock Intelligence, MSD Animal Health Intelligence, USA). …”
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Population-Level Dissemination of a Smoking Cessation Smartphone App: Quasi-Experimental Comparison of Values-Based Messages in Social Media Advertisements by Jonathan B Bricker, Margarita Santiago-Torres, Kristin E Mull, Brianna M Sullivan, Ravi Mehrotra

“…The study population included a selected media market of individuals living in 7 metro cities of India – Delhi, Mumbai, Kolkata, Chennai, Bengaluru, Hyderabad, and Pune – who were exposed to one of 6 social media advertisements from January 16 to May 5, 2024. MethodsThe advertisement campaign design for each of the identified values, based on previous smoking cessation trial data, followed a collaborative iterative process. …”
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Recruiting Medical, Dental, and Biomedical Students as First Responders in the Immediate Aftermath of the COVID-19 Pandemic: Prospective Follow-Up Study by Nicolas Schnetzler, Victor Taramarcaz, Tara Herren, Eric Golay, Simon Regard, François Mach, Amanta Nasution, Robert Larribau, Melanie Suppan, Eduardo Schiffer, Laurent Suppan

“…MethodsThis was a prospective follow-up study, conducted between November 2021 and March 2022 at the University of Geneva Faculty of Medicine, Geneva, Switzerland. …”
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Merging of the Fukushima Health Management Survey With the National and Local Cancer Registry to Refine the Detection of Thyroid Cancer Cases After the 2011 Fukushima Daiichi Nucle... by Reiko Kimura‐Tsuchiya, Masanori Nagao, Shigehira Saji, Fumikazu Hayashi, Tetsuya Ohira, Hiroki Shimura, Fumihiko Furuya, Satoru Suzuki, Satoshi Suzuki, Tetsuo Ishikawa, Susumu Yokoya, Hitoshi Ohto, Seiji Yasumura

“…Methods The FHMS‐eligible residents' information was supplemented by merging and cross‐validating the FHMS and CR data using the Fukushima Prefectural Cancer Registry (FPCR), 2008–2015, and the National Cancer Registry (NCR), 2016–2018. …”
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GULP1 as a novel diagnostic and predictive biomarker in hepatocellular carcinoma by Hyung Seok Kim, Jung Hwan Yoon, Ji Yi Choi, Moon Gyeong Yoon, Geum Ok Baek, Minji Kang, Se Ha Jang, Won Park, Yunjin Go, Jestlin Tianthing Ng, Suk Woo Nam, Jee-Yeong Jeong, Ji Eun Han, Hyo Jung Cho, Su Bin Lim, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun

“…Methods We analyzed genomic datasets from The Cancer Genome Atlas and Gene Expression Omnibus databases via least absolute shrinkage and selection operator Cox regression and 10-fold cross-validation, leading to the development of a 15-gene risk score model, which was validated using three independent datasets. …”
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