Uncertainty-aware automatic TNM staging classification for [18F] Fluorodeoxyglucose PET-CT reports for lung cancer utilising transformer-based language models and multi-task learni... by Stephen H. Barlow, Sugama Chicklore, Yulan He, Sebastien Ourselin, Thomas Wagner, Anna Barnes, Gary J.R. Cook

“…This is combined with an uncertainty classification task (‘u’) to account for studies with ambiguous TNM status. Methods 2498 reports were annotated by a nuclear medicine physician and split into train, validation, and test datasets. …”
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Polymer-Functionalized Magnetic Nanoparticles for Targeted Quercetin Delivery: A Potential Strategy for Colon Cancer Treatment by Júlia Borges de Macedo, Julia Narayana Schoroeder Bueno, Carla Cristine Kanunfre, José Ricardo de Arruda Miranda, Andris Figueiroa Bakuzis, Priscileila Colerato Ferrari

“…Therefore, this study aimed to develop chitosan (CS) and folate-chitosan (FA-CS)-coated MNP to improve the stability and targeting of the system for quercetin (Q) delivery. <b>Methods</b>: After FA-CS synthesis and 3² factorial design, polymer-functionalized MNPs were produced for quercetin loading, characterized, and evaluated by drug dissolution and cytotoxicity assay. …”
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Simplified clinical algorithm for identifying patients eligible for immediate initiation of antiretroviral therapy for HIV (SLATE): protocol for a randomised evaluation by Mhairi Maskew, Bruce A Larson, Isaac Tsikhutsu, Margaret Bii, Peter D Ehrenkranz, Sydney Rosen, Matthew P Fox, Alana T Brennan, WD Francois Venter

“…For this policy of ‘treat all’ to succeed, millions of new patients must be initiated on ART as efficiently as possible. Studies have documented high losses of treatment-eligible patients from care before they receive their first dose of antiretrovirals (ARVs), due in part to a cumbersome, resource-intensive process for treatment initiation, requiring multiple clinic visits over a several-week period.Methods and analysis The Simplified Algorithm for Treatment Eligibility (SLATE) study is an individually randomised evaluation of a simplified clinical algorithm for clinicians to reliably determine a patient’s eligibility for immediate ART initiation without waiting for laboratory results or additional clinic visits. …”
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Development and Certification of Calcium Chloride Casein Reference Standard by S. M. Sukhanova, R. A. Volkova, N. E. Zakharova, O. V. Fadeikina

“…In accordance with the requirements of the State Pharmacopoeia of the Russian Federation, 14th edition, Clostridium novyi 198 test strain is used to determine growth promoting properties of thioglycollate medium when testing sterility of immunobiological medicinal products. …”
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Chromato-mass spectroscopy of tinctures from the underground part of Valerian plants growing in Zaporizhzhia region by V. M. Odyntsova, Yu. I. Korniievskyi, D. Yu. Skoryna, V. Н. Korniievska

“…In the 18th century, valerian was included in all European pharmacopeias. High efficiency, good tolerability, and virtually no side effects ensure the widespread use of valerian and its phytopreparations in medical practice, especially for the treatment of geriatric patients. …”
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The effect of tactile versus auditory stimulation on reducing pain associated with invasive procedures among preterm neonates at NICUs by Entsar Shehata Mohammed, Seham Mohammed Elmwafie, Fatma Sayed Abdelaziz Mohamed, Safaa Salah Ismail

“…The study aimed to determine the effect of tactile versus auditory stimulation on reducing pain associated with invasive procedures among preterm neonates at NICUs. …”
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Motherhood unveiled: examining the dynamic relationship between sleep quality and breastfeeding confidence in postpartum primiparous women in Syria: a cross-sectional study by Alaa Aldairy, Jamal Ataya, Dana Haymoun, Roula Samer Kashlan, Joudi Kouran, Nagham Amouna, Dema Adwan, Marwan Alhalabi

“…Materials and methods This descriptive study included 316 primiparous women who delivered babies in Damascus, Syria. …”
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A novel integrated approach to predict the sodium absorption ratio (SAR) of groundwater sustainability using deep learning models and SHAP approach by Kanak N. Moharir, Chaitanya Baliram Pande, Rabin Chakrabortty, Malay Pramanik, Balamurugan Paneerselvam, Okan Mert Katipoğlu, Subodh Chandra Pal, Miklas Scholz, Krishna Kumar Yadav, Lamjed Mansour, Mohamed Elsahabi

“…The prediction results are evaluated with the use of different performance metrics, mean absolute error (MAE), mean absolute relative error (MARE), Nash Sutcliffe efficiency (NSE), root mean squared error (RMSE), and coefficient of determination (R 2). …”
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Comparative assessment of standalone and hybrid deep neural networks for modeling daily pan evaporation in a semi-arid environment by Mohammed Achite, Manish Kumar, Nehal Elshaboury, Aman Srivastava, Ahmed Elbeltagi, Ali Salem

“…Model performances were compared using mean absolute error (MAE), root mean square error (RMSE), determination coefficient (R2), Nash–Sutcliffe efficiency (NSE) coefficient, and percentage bias (PBIAS). …”
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The P Balasubramaniam Award-2024 Singapore Orthopaedic Association Annual Scientific Meeting Award: Novel artificial intelligence algorithm for soft tissue balancing and bone cuts... by Matthew Song Peng Ng, Ryan Wai Keong Loke, Melvin Kian Loong Tan, Yau Hong Ng, Zi Qiang Glen Liau

“…We aim to demonstrate the effectiveness of our novel algorithm in terms of accuracy and surgical duration. Methods We developed a novel AI computational algorithm to optimize rTKA implant positioning in three-dimensional space. …”
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EMCC dispatch priority for trauma patients in Norway: a retrospective cohort study by Inger Marie Waal Nilsbakken, Torben Wisborg, Stephen Sollid, Elisabeth Jeppesen

“…Methods This registry-based study included 3633 patients from the Norwegian Trauma Registry and Oslo EMCC during 2019–2020. …”
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Evaluation of Stress Hormone Levels, Preoperative Anxiety, and Information Needs before and after Hysteroscopy under Local Anesthesia in Relation to Transvaginal Procedures under G... by Karolina Chmaj-Wierzchowska, Katarzyna Wszołek, Adrian Nowak, Natalia Ignaszak-Kaus, Magdalena Muszyńska, Maciej Wilczak

“…To determine cortisol and prolactin levels using electrochemiluminescence, blood was collected from the patients on the day of admission to the hospital, i.e., the day of surgery, in the morning, while fasting. …”
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HIV treatment as prevention: systematic comparison of mathematical models of the potential impact of antiretroviral therapy on HIV incidence in South Africa. by Jeffrey W Eaton, Leigh F Johnson, Joshua A Salomon, Till Bärnighausen, Eran Bendavid, Anna Bershteyn, David E Bloom, Valentina Cambiano, Christophe Fraser, Jan A C Hontelez, Salal Humair, Daniel J Klein, Elisa F Long, Andrew N Phillips, Carel Pretorius, John Stover, Edward A Wenger, Brian G Williams, Timothy B Hallett

“…<h4>Methods and findings</h4>Twelve independent mathematical models evaluated a set of standardised ART intervention scenarios in South Africa and reported a common set of outputs. …”
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Econometric predictive model for assessing the functional state of students during the examination period: a cross-sectional exploratory pilot study by I. S. Knyazhev, L. V. Karaulova, O. V. Reztsov, A. P. Spitsin

“…Methods. The cohort observational study enrolled 74 students of Kirov State Medical University, aged 18–23 years, who gave consent to the survey. …”
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Cross-sectional and longitudinal validation of the Slovene version of the health-related quality of life questionnaire in patients with Hymenoptera venom allergy (HRQLH-S) by T. Močnik, J. Šelb, M. Peršolja, M. Košnik

“…Methods The “Vespid Allergy Quality of Life Questionnaire” (VQLQ), developed by Oude Elberink et al., has become a well-established diagnostic instrument. …”
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Comparison of the performances of six empirical mass transfer-based reference evapotranspiration estimation models in semi-arid conditions by Selçuk Usta

“…The statistical approaches of the mean absolute error (MAE), mean absolute percentage error (MAPE), root mean square error (RMSE), Nash–Sutcliffe Efficiency (NSE), and determination coefficient (R2) were used as comparison criterion. …”
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Nicotinamide mononucleotide biosynthesis and the F-actin cytoskeleton regulate spindle assembly and oocyte maturation quality in post-ovulatory aged porcine oocytes by Hyo-Jin Park, Seul-Gi Yang, Ji-Hyun Shin, Seung-Bin Yoon, Ji-Su Kim, Deog-Bon Koo

“…Here, we investigated the mechanisms by which the NAD+ salvage pathways function in poor oocyte maturation upon POA through the F-actin cytoskeleton. Methods Porcine oocytes were aged by extending in vitro maturation (IVM) for an additional 24 h to create a POA model. …”
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Enhanced Intranasal Delivery of Atorvastatin via Superparamagnetic Iron-Oxide-Loaded Nanocarriers: Cytotoxicity and Inflammation Evaluation and In Vivo, In Silico, and Network Phar... by Kristina Zarif Attalla, Doaa H. Hassan, Mahmoud H. Teaima, Carol Yousry, Mohamed A. El-Nabarawi, Mohamed A. Said, Sammar Fathy Elhabal

“…<b>Objective</b>: This study aims to develop an intranasal (IN) delivery system for glioblastoma multiforme (GBM) management using repurposed superparamagnetic iron-oxide (SPION) loaded with atorvastatin (ATO)-nanostructured lipid carrier (NLC). <b>Methods</b>: Emulsification and ultrasonication were used to formulate ATO-NLCs, and the best formula was loaded with SPION to make the final atorvastatin/superparamagnetic iron oxide-loaded nanostructured lipid carrier (ASN) formulation. …”
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Investigating the relationship between Pfkelch13 mutations and response to artemisinin-based treatment for uncomplicated falciparum malaria: a protocol for a systematic review and... by Prabin Dahal, Philippe Guerin, Farhad Shokraneh, James A Watson, Karen I Barnes, Aboubakar Soma, Stephanie van Wyk, Chistevy Vouvoungui, Dhol S Ayuen

“…ART-R has been causally linked to specific mutations in the Pfkelch13 gene.Methods and analysis The systematic review and associated meta-analysis aim to determine the correlation between Pfkelch13 (alleles present in the Kelch13 gene region of the P. falciparum parasite) genotypes and clinical and parasitological response to ACTs from a globally representative data set pooling individual patient data (IPD) from eligible published and unpublished studies. …”
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Factors influencing value-based care application among medical students and postgraduate in Thailand by Phoomjai Sornsenee, Kittisakdi Choomalee, Kamonlak Sanphet, Kanyarat Keereerak, Techin Wongwatthanawisit, Tanyamon Wongtabpabud, Panpim Tipphayawong, Panupong Khunjun, Suppanita Tularak, Kanisorn Sungkaro, Theepat Wongkittithaworn

“…Abstract Background The adoption of Value-Based Care (VBC) is essential for enhancing healthcare quality and efficiency, with implications for future healthcare delivery. …”
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