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6681
Purification and Molecular Characterization of a Mammalian Neurotoxin as a Pharmaceutical Tool from the Venom of Iranian Scorpion Androctonus crassicauda
Published 2025-03-01“…To gain greater insights into the structural and functional impacts of toxins from Androctonus crassicauda (Buthidae), a dangerously venomous scorpion species, its venom was isolated, purified, and characterized. Methods: Long chain toxin with four disulfide bonds purified by size exclusion chromatography and reversed-phase HPLC and characterized by amino acid sequencing and molecular weight determination. …”
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6682
Oxidative phosphorylation in brown adipose tissue in a type II diabetes mellitus mouse model after forced treadmill running
Published 2024-04-01“…To study the effect of forced exercises on the content and parameters of oxidative phosphorylation in brown adipose tissue of mice with type II diabetes mellitus.Materials and methods. To model the disease, we used a high-fat diet and physical exercises in the form of forced treadmill running for 4 weeks. …”
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6683
Silver-hollow mesoporous silica nanoparticles for clarithromycin delivery in an animal model of helicobacter pylori
Published 2025-07-01“…Background: Nanoparticle-based drug delivery systems offer a promising approach to overcoming antimicrobial resistance and enhancing therapeutic efficacy.Objective(s): This study aimed to evaluate the efficacy of silver-hollow mesoporous silica nanoparticles (Ag-HMSNs) in the targeted delivery of clarithromycin for eradicating Helicobacter pylori (H. pylori).Materials and Methods: A synergistic formulation comprising silver nanoparticles and clarithromycin-loaded hollow mesoporous silica nanoparticles (Ag-HMSNs@CLT) was examined for its antibacterial activity against H. pylori. …”
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6684
Circadian Regulator-Mediated Molecular Subtypes Depict the Features of Tumor Microenvironment and Indicate Prognosis in Head and Neck Squamous Cell Carcinoma
Published 2023-01-01“…Herein, the present study set out to explore the significance of circadian regulator genes (CRGs) in HNSCC. Materials and Methods. The molecular landscape and clinical significance of 13 CRGs in HNSCC were explored based on The Cancer Genome Atlas (TCGA). …”
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6685
Improving Bus Operations through Integrated Dynamic Holding Control and Schedule Optimization
Published 2018-01-01“…Results show that the proposed model significantly reduce passengers average travel time compared with existing methods.…”
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6686
Extracellular Volume Derived from Equilibrium CT for the Prediction of Survival Outcomes in Patients with Pancreatic Ductal Adenocarcinoma
Published 2025-04-01“…Methods This retrospective study included 83 patients who underwent CT and R0 resection between January 2016 and September 2023. …”
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6687
STATE POLICY AS A TOOL FOR INCREASING THE INTERNATIONAL COMPETITIVENESS OF THE NATIONAL ECONOMY
Published 2025-06-01“…The methodological basis of the work is a set of general scientific and special research methods, in particular analysis and synthesis, induction and deduction, comparative analysis, and a systemic approach. …”
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6688
Novelty in the treatment of episodic tension-type headache
Published 2010-12-01“…Nonsteroidal anti-inflammatory drugs (NSAIDs) whose efficiency is determined by the rapid and complete regression of cephalgia are primarily used to relieve an ETTH attack. …”
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6689
Understanding what really helps to ensure access to diagnostic services in the Indian Public Health System: a realist synthesis of the Common Review Mission reports (2007-2021)
Published 2023-07-01“…The objective of the study was to understand key health system factors augmenting or limiting access to diagnostic services and outcomes. # Methods Common Review Mission (CRM) reports between 2007 and 2021 were selected for the study. …”
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6690
Pathomorphological changes of the vascular bed and the state of collateral blood flow in cerebral infarction
Published 2020-08-01“…To study the pathomorphological changes of the vascular bed and the state of collateral blood flow in cerebral infarction. Materials and methods. The brains of 45 deceased patients with hemispheric infarctions with different terms of the disease were studied during the work. …”
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6691
The Concession Agreement as a Form of Involving Small Private Companies into the Effective Management of State Property
Published 2017-12-01“…In accordance with the problem defined the purpose of the study is the proposal of measures for effective management of state property. Determined that the licensing system existing in the Russian Federation, have shown their high efficiency in the development of large mineral deposits, but for the development of small man-made deposits it is not effective. …”
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6692
Development of Theory of Economic Diplomacy in Russia in 2000-2018: Scientometric and Institutional Analysis
Published 2019-02-01“…Thus, the consolidation of relevant research centres, competition between them, as well as the overall development of this practice-oriented theoretical direction by its nature are the key to improving the efficiency of Russian foreign policy. On this basis, through the scientometric analysis of methods and tools adapted to the goals and objectives of the project, an institutional map of the scientific community involved in economic diplomacy was drawn up. …”
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6693
Analysis of atmospheric deposition in the territory of the Republic of North Ossetia-Alania by biomonitoring data
Published 2023-03-01“…The assessment of the possibility of using mosses as biomonitors for determining the content of heavy metals and other trace elements in the atmosphere of the territory of the Republic of North Ossetia-Alania.Material and Methods. …”
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6694
COMPLEMENTARY INSTITUTIONS FOR FUNDING REGIONAL ECONOMIES
Published 2017-09-01“…With this purpose the paper examines regional banking structures and non-bank funding institutions. The research methods included the institutional analysis, the structural and dynamic analysis of the Bank of Russia data and regional statistics. …”
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6695
OPTIMIZATION OF COMMODITY STOCKS THE ENTERPRISE BY MEANS OF HML-FMR CLUSTERING
Published 2020-10-01“…To conduct the study, statistical information was used on commodity resources of the enterprises, statistical methods (grouping, structure analysis, estimation of dynamic series), tools for assessing the efficiency of inventory use, HML-FMR clustering were used. …”
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6696
The efficacy of moxifloxacin in patients with bacterial keratitis
Published 2018-01-01“…Methods. The study was designed as prospective, randomized, double-blind study. …”
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6697
Specialized Mobile Applications as Means of Optimizing the Power Supply System of the Republic of Belarus
Published 2020-03-01“…Their properties, main qualities and advantages over traditional methods of “business – client” interaction are considered. …”
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6698
ON INCREASING ENERGY SECURITY OF BELARUS
Published 2016-09-01“…Therefore, in the energy sector energy efficiency should be increased through the use of its own energy resources. …”
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6699
FIELD ASSESSMENT OF ACCESSIONS FROM THE MAIZE COLLECTION FOR RESISTANCE TO BOIL SMUT
Published 2019-10-01“…Background. The efficiency of heterotic breeding is determined by reasonable selection of the lines with the best combining abilities and important breeding traits. …”
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6700
Theoretical study of soil water balance and process of soil moisture evaporation
Published 2017-02-01“…But crop production efficiency there depends on amount of moisture, available to plants. …”
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