Adaptive gradient scaling: integrating Adam and landscape modification for protein structure prediction by Vitalii Kapitan, Michael Choi

“…Abstract Background Protein structure prediction is one of the most important scientific problems, on the one hand, it is one of the NP-hard problems, and on the other hand, it has a wide range of applications including drug discovery and biotechnology development. Since experimental methods for structure determination remain expensive and time-consuming, computational structure prediction offers a scalable and cost-effective alternative and application of machine learning in structural biology has revolutionized protein structure prediction. …”
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Presidential elections of 1997: a comparative analysis of electoral provisions and stereotypes by Lauras Bielinis

“…In fact, the politicians were nevertheless trying to provoke and renovate this efficient value-classificative distribution to the furthest possible extent. …”
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IL-19 as a promising theranostic target to reprogram the glioblastoma immunosuppressive microenvironment by Gilbert Aaron Lee, Justin Bo-Kai Hsu, Yu-Wei Chang, Li-Chun Hsieh, Yi-Tien Li, Ying Chieh Wu, Cheng-Ying Chu, Yung-Hsiao Chiang, Wan-Yuo Guo, Chih-Chun Wu, Liang-Wei Chen, Hung-Wen Kao, Wan-Li Lin, Li‑Wen Tseng, Ting-Wei Weng, Duen-Pang Kuo, Sho-Jen Cheng, Yung-Chieh Chen, Shiu-Wen Huang, Hsing-Jien Kung, Cheng-Yu Chen

“…Targeting GBM-mediated immunosuppressive and invasive properties is a promising strategy to improve clinical outcomes. Methods We utilized clinical and genomic data from the Taiwan GBM cohort and The Cancer Genome Atlas (TCGA) to analyze RNA sequencing data from patient tumor samples, determining the association of interleukin-19 (Il-19) expression with survival and immunosuppressive activity. …”
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Efikasnost terapijskog monitoringa ciklosporina određivanjem C2 i PIK0−4 tokom prva 24 meseca posle transplantacije bubrega by Vavić Neven, Ignjatović Ljiljana, Drašković Biljana, Hrvačević Rajko, Kovačević Zoran, Paunić Zoran

“…Graft function in both groups was good during the period of two years. CyA dose determination through C2 and AUC0-4 is efficient TDM method, relatively simple for use in day to day clinical practice.…”
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APPLICATION OF SLAG FILLERS IN THE ASPHALT CONCRETE COMPOSITION FOR INCREASING THE ROAD COATING’S DURABILITY by A. T. Pimenov, V. S. Pribylov

“…The issue under consideration is relevant by finding more efficient building materials in the context of the development of resource-saving technologies and increasing environmental requirements in the Russian regions.Materials and methods. …”
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Unsupervised Identification for 2-Additive Capacity by Principal Component Analysis and Kendall’s Correlation Coefficient in Multi-Criteria Decision-Making by Xueting Guan, Kaihong Guo, Ran Zhang, Xiao Han

“…The optimization model equipped with a new form of monotonicity conditions is then established to further determine the optimal Shapley interaction index. With these two kinds of indices, a desired monotone 2-additive capacity is finally identified in an objective and efficient manner. …”
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The study of socio economic factors’ influence on the capacity dynamics of the pharmaceutical market in contracting conditions by А. А. Kotvitska, V. H. Kostiuk

“…In order to determine the dependence of the influence of socio economic factors on the quantitative potential of the pharmaceutical market and prediction of its development, we developed and tested on the example of a group of dexketoprofen the method of predicting the capacity of the pharmaceutical market with the definition of factors influencing its size, which is based on the correlation-regression method of analysis and which consists of eight main stages. …”
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Noise reduction in brain magnetic resonance imaging using adaptive wavelet thresholding based on linear prediction factor by Ananias Pereira Neto, Ananias Pereira Neto, Fabrício J. B. Barros

“…This factor leverages temporal information and features from both the original and noisy images to determine a weighted threshold. This dynamic thresholding approach aims to selectively reduce or eliminate noise coefficients while preserving essential image features.ResultsThe proposed method was rigorously evaluated against existing state-of-the-art noise reduction techniques. …”
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Evaluation of relationship between histopathological lesions and cardiac biomarkers changes in lambs with foot and mouth disease by Zahra Jafarnia, Mohammad Hashemnia, Zahra Nikoosafat

“…Although these methods are very efficient, they are usually expensive and time-consuming. …”
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Expectation maximization based framework for joint localization and parameter estimation in single particle tracking from segmented images. by Ye Lin, Sean B Andersson

“…Our results indicate our EM based methods outperform the standard techniques, especially at low signal levels. …”
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Navigating the Purification Process: Maintaining the Integrity of Replication-Competent Enveloped Viruses by Adrian Schimek, Judy King Man Ng, Jürgen Hubbuch

“…To assess the impact of process steps on particles and determine their quality and integrity, advanced analytical methods are required. …”
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DESIGNING OF INDEPENDENT PROFESSIONAL DEVELOPMENT PATH AS A MEANS OF SUCCESSFUL VOCATIONAL TRAINING by Svetlana A. Lysuenko

“…The research data have proved that the pupils with the ability and readiness for designing of the individual professional future during vocational training have the following skills: they can accurately formulate their professional purposes; they can determine the ways of its achievement correctly and efficiently; these students realize the importance of own activity in the course of professional evolvement; and they demonstrate higher educational and professional achievements becoming more qualified experts. …”
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Study of Oxidative–Reductive Potential Changes in the Enrichment of Oxidized Polymetallic Ores by Alima Mambetaliyeva, Tansholpan Tussupbekova, Leyla Sabirova, Guldana Makasheva, Kanay Rysbekov, Madina Barmenshinova

“…The highest beneficiation efficiency was achieved within the ORP range of −160 to −200 mV, beyond which lead recovery began to decline. …”
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Enhancing renewable energy integration through strategic stochastic optimization planning of distributed energy resources (Wind/PV/SBESS/MBESS) in distribution systems by Ahmad K. ALAhmad, Renuga Verayiah, Hussain Shareef, Agileswari Ramasamy, Saleh Ba-swaimi

“…Monte Carlo Simulation (MCS) models uncertainties in wind speed, solar irradiation, load power, and energy prices, while the backward reduction method (BRM) mitigates computational complexities. …”
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A lightweight hybrid model for accurate ammonia prediction in pig houses by Jacqueline Musabimana, Qiuju Xie, Hong Zhou, Ping Zheng, Honggui Liu, Tiemin Ma, Jiming Liu

“…It also outperforms the standard transformer in accuracy and efficiency, with Root Mean Square Error (RMSE), Mean Absolute Percentage Error (MAPE), and coefficient of determination R² of 0.3994, 0.0225, and 0.9260, respectively, compared to 0.4250, 0.0227, and 0.9162 for the standard model, reducing RMSE by 5.99 %, MAPE by 0.88 %, and increasing R² by 1.08 %. …”
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Microwave-high temperature steaming assisted enzymatic extraction of soluble dietary fiber from Dajiao (Musa paradisiaca L. spp. sapientum (L.), AAB) by Lixia Wang, Yuting Ding, Muhammad Rizwan, Zheli Ding, Yingdui He

“…The results indicate that the microwave high temperature steaming assisted enzymatic extraction method enhances the SDF content, promotes efficient utilization of banana peel waste, and provides a meaningful reference for extracting and using dietary fiber from banana pulp.…”
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Transition and continuation scheme of open-pit mining area under complex engineering geological conditions by Guangwei LIU, Junxiong TU, Weiqiang GUO, Yuxuan HAN, Chunlin LI, Yu BAI, Mingyu YU, Ruijun JIA

“…When large-scale near-level coal field adopts open-pit mining, in order to realise safe and efficient production and recover the investment cost as soon as possible, it usually adopts the way of mining in sub-districts, so before the old mining area is about to reach the boundary, it is inevitable to consider the problem of the transition succession between the old and new mining areas. …”
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Tackling the unyielding: testing two novel approaches against NDM-producing Enterobacterales and Pseudomonas aeruginosa isolates collected in India by Yamuna Devi Bakthavatchalam, Bijayini Behera, Anand Shah, Purva Mathur, Raja Ray, Bashir Ahmed Fomda, Kamini Walia, Balaji Veeraraghavan

“…Minimum inhibitory concentrations of antibiotics against multicentric NDM-producing Escherichia coli (n = 117), Klebsiella pneumoniae (n = 103), and P. aeruginosa (n = 72) were determined by the reference broth microdilution method. …”
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In-situ graphene modified pencil graphite electrode for the simultaneous electrochemical detection of ascorbic acid, dopamine and uric acid by Pham Van Dat, Le Khanh Toan, Pham Huyen Thuong, Nguyen Van Anh, Nguyen Van Thuc, Nguyen Xuan Viet

“…Differential pulse voltammetry (DPV) was utilized for quantitative determination, yielding high sensitivities with calibration slopes of 56.9 μA/mM for AA, 37.4 μA/μM for DA, and 11.6 μA/μM for UA. …”
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Applied AMT machine learning and multi-objective optimization for enhanced performance and reduced environmental impact of sunflower oil biodiesel in compression ignition engine by Ali A. Al-jabiri, Hyder H. Balla, Mudhaffar S. Al-zuhairy, Hussein Alahmer, Ahmed Al-Manea, Raed Al-Rbaihat, Ali Alahmer

“…The AMT models demonstrate high prediction accuracy, with coefficient of determination (R2) values exceeding 0.98.…”
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