Centrifugation versus filtration-based cell salvage: impact on perioperative bleeding in cardiac surgery—the COLTRANE randomised clinical trial – study protocol by Christine Mouton, Nicolas Nesseler, Antoine Bénard, Mathieu Pernot, Alexandre Ouattara, Antoine Beurton, Alexandre Mansour, Victor-emmanuel Brett, Corinne Batsale, Anais Aitgougam, Anais Cordon, Aurelie Fresselinat, Geraldine Robert, Julien Imbault

“…The main objective is to determine whether the filtration-based SAME device reduces significant perioperative bleeding compared with the centrifugation-based system in high-risk cardiac surgery patients.Methods and analysis The Centrifugation-based vs filtration-based intraOperative cell saLvage on qualiTy of peRioperAtive haemostasis iN cardiac surgEry (COLTRANE) trial is a multicentre, parallel-group, single-blinded, superiority-randomised clinical trial. …”
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Small extracellular vesicles derived from mesenchymal stromal cells loaded with β-nicotinamide mononucleotide activate NAD+/SIRT3 signaling pathway-mediated mitochondrial autophagy... by Zixuan Sun, Jiali Li, Yuzhou Zheng, Jiaxin Zhang, Wenhuan Bai, Xinyi Deng, Zhijing Wu, XueZhong Xu, Wei Ding, Hui Qian, Yulin Tan

“…Based on this, we applied electroporation to construct NMN-loaded hucMSC-sEVs (NMN-sEVs) to improve their stability and efficacy and to enhance their potential for translational application in medical aesthetics and anti-aging. Methods D-galactose was applied to construct a mouse skin aging model, based on which comparative analyses of topical and nano-microneedle administration were performed to determine the optimal delivery method of sEVs in vivo experiments. …”
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Glutamine-αKG axis affects dentin regeneration and regulates osteo/odontogenic differentiation of mesenchymal adult stem cells via IGF2 m6A modification by Qinglu Tian, Shiqi Gao, Siying Li, Mian Wan, Xin Zhou, Wei Du, Xuedong Zhou, Liwei Zheng, Yachuan Zhou

“…Inhibition of glutamine-αKG axis may affect IGF2 translation efficiency via m6A methylation and can be significantly rescued by αKG supplementation. …”
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Spectrum of mutations and their phenotypic manifestations in children and adults with long QT syndrome by N. N. Chakova, S. M. Komissarova, E. A. Zasim, T. V. Dolmatovich, E. S. Rebeko, S. S. Niyazova, E. V. Zaklyazminskaya, L. I. Plashchinskaya, M. V. Dudko

“…Aim. To determine the spectrum of mutations in the genes responsible for the long QT syndrome (LQTS) and study their phenotypic manifestations in patients with LQTS in different age groups.Materials and methods. …”
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The Diagnostic Value of Serum Gastrin-17 and Pepsinogen for Gastric Cancer Screening in Eastern China by Hongzhang Shen, Kangwei Xiong, Xiangyu Wu, Sile Cheng, Qifeng Lou, Hangbin Jin, Xiaofeng Zhang

“…Methods. The serum concentrations of G-17 and pepsinogen I and II (PGI and PGII) in 834 patients were analyzed, and the PGI/PGII ratio (PGR) was calculated. …”
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Effects of autolytical fish protein hydrolysate on growth performance, survival rate, and hematological indices in farmed juvenile beluga, Huso huso by Ali Hosseinpour Zelaty

“…They have been found to enhance fish growth, feed efficiency, immune responses, and disease resistance. …”
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Experiment of double grits scribing 2D SiCf/SiC composite by Jinzhu GUO, Yao LIU, Youzhe WANG, Dong WANG

“…ObjectivesTo improve the grinding quality and efficiency, reveal the material removal mechanism of SiCf/SiC composites, and determine the coupling effect among abrasives during grinding.MethodsFirstly, uniaxial tensile, shearing, and bending experiments of SiC fiber bundles are conducted to observe damage modes. …”
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Diseño óptimo multiobjetivo y planificación del proceso de fabricación (CAD/CAPP) de redes de conductos de climatización // Optimal design and planning of the manufacturing process... by A. Cordovés García, C. J. Arzola Ruíz, J. R. Hechavarría Hernández, M. R. Fernández Peña

“…<br />The system we now introduce is able to carry out the optimum automated design of the pipelines used for room air<br />conditioning, through the analysis and evaluation of the main criteria that determine the efficiency of the installation. Among<br />these are the production costs and power consumption.…”
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THE FIRST RUSSIAN STRATEGIC STUDY OF PHARMACOTHERAPY FOR RHEUMATOID ARTHRITIS (REMARCA TRIAL): RESULTS OF 12-MONTH TREATMENT IN 130 PATIENTS by D. E. Karatee, E. L. Luchikhina, N. V. Demidova, G. S. Gridneva, M. A. Kanonirova, Yu. V. Muravyev, G. V. Lukina, Yu. A. Olyunin, K. A. Kasumova, E. N. Aleksandrova, A. A. Novikov, A. A. Avdeeva, T. V. Popkova, D. S. Novikova, A. V. Smirnov, A. V. Volkov, E. L. Nasonov

“…To introduce treat-to-target recommendations is an important task of modern rheumatology; however, there is still a diversity of serious problems relating to a scientific rationale and a clinical one for this strategy and to the possibilitiesof its implementation in real clinical practice, in the rheumatology service of the Russian Federation in particular, by taking into account the specific features of funding for high-tech medical care.Objective: to determine the efficiency and safety of combined therapy with subcutaneous methotrexate (MT) and biological agents (BA) when using the treat-to-target strategy in patients with active early and extended-stage rheumatoid arthritis (RA) who have risk factors for a poor prognosis.Subjects and methods. …”
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Dynamics of T cell subpopulation in patients with aplastic anemia during immunosuppressive therapy by A. V. Abramova, E. A. Mikhailova, I. V. Galtseva, Z. T. Fidarova, A. V. Luchkin, N. M. Kapranov, Yu. O. Davydova, S. M. Kulikov, V. V. Troitskaya, E. N. Parovichnikova

“…To investigate the T cells subpopulation in bone marrow of AA patients during IST.Materials and methods. The study included 41 patients over 18 years of age with newly diagnosed acquired AA without previous IST. …”
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CYP2C9 Polymorphism Study in Patients with Acute Back Pain and its Impact on the Effectiveness of Treatment with the Non-Steroidal Anti-Inflammatory Drugs by Maslova I., Mykhailovska N., Slobodin T.

“…All patients underwent a genetic test – the determination of the allelic variants CYP2C9*2 and CYP2C9*3 CYP2C9 gene with polymerase chain reaction (PCR). …”
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Application of dry electrodes in supercapacitors and lithium-ion batteries by Guolei ZHANG, Keliang ZHANG, Yabin AN, Chen LI, Guanwei LIU, Xianzhong SUN, Changzhou YUAN, Kai WANG, Xiong ZHANG, Yanwei MA

“…With the increasing demand for electrochemical energy storage, the lithium-ion battery industry faces new challenges, such as improving production efficiency, reducing energy consumption, and enhancing battery performance, especially for next-generation batteries. …”
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Relación entre la calidad del sueño y manifestaciones tempranas del síndrome de sobreentrenamiento físico en futbolistas colombianos (Relationship between sleep quality and early m... by Martín Hernán Bonilla Obando, Nelson Fernelly Gonzalez Cetina, Sandra Patricia Cárdenas Ojeda, Diana Paola López Velandia

“…Materials and Methods: A descriptive cross-sectional study was conducted involving male soccer players in Colombia. …”
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Clinical course and outcomes of COVID-19 infection in liver transplant recipients: single-center cross-sectional study by S. E. Voskanyan, A. I. Sushkov, V. S. Rudakov, D. S. Svetlakova, M. V. Popov, A. N. Pashkov, M. Muktarzhan, A. S. Lukianchikova

“…Despite this, there were no large Russian studies of COVID-19 course and outcomes in liver transplant recipients.The study purpose was to determine prevalence, clinical course, severity, outcomes of COVID-19, as well as to assess the safety and efficiency of vaccination for disease prevention in liver transplant recipients.Material and methods. 260 recipients (71% of all patients at risk of COVID-19 disease) who underwent liver transplantation at State Research Center – Burnasyan Federal Medical Biophysical Center from May 2010 to September 2021 were included in a single-center cross-sectional study. …”
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Proposing a two-stage screening approach to distinguish between transient and enduring postnatal depressive symptoms: A prospective cohort study by Johanne Smith-Nielsen, Ida Egmose, Stephen Matthey, Maria Stougård, Sophie Reijman, Mette Skovgaard Væver

“…This approach significantly improves referral efficiency and minimizes over-pathologization, enhancing clinical practice in perinatal mental health.…”
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The relation of changes in intraoperative EEg and ECog with age, anamnesis duration and outcome of surgical treatment in children with symptomatic epilepsy by A. B. Kozlova, M. B. Korsakova, N. A. Arkhipova, P. A. Vlasov, A. G. Melikyan, L. V. Shishkina, E. L. Masherov

“…To reveal relation of change in intraoperative electroencephalography (EEG), electrocorticography (EсoG) with age of patients, the anamnesis duration, localization and type of pathology, the result of treatment.   Materials and methods. 64 patients with symptomatic epilepsy operated at N.N. …”
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Physical wedge as a tool for radiochromic film calibration by Stevan Pecić, Miloš Vićić, Ivan Belča, Strahinja Stojadinović, Borko Nidžović, Ljubomir Kurij, Slobodan Dević

“…The aim was to establish an efficient and reproducible method for calibrating RCF using a PW. …”
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Techno-Economic Analysis of Flare Gas to Hydrogen: A Lean and Green Sustainability Approach by Felister Dibia, Oghenovo Okpako, Jovana Radulovic, Hom Nath Dhakal, Chinedu Dibia

“…Subsequently, an economic evaluation was performed to determine the levelized cost of hydrogen (LCOH) and the cost–benefit ratio (CBR) for Nigeria. …”
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Study on Fire Resistance Ability and Mechanical Properties of Composites Based on Epikote 240 Epoxy Resin and Thermoelectric Fly Ash: An Ecofriendly Additive by Tuan Anh Nguyen, Quang Tung Nguyen, Xuan Canh Nguyen, Van Hoan Nguyen

“…These results showed that fly ash is an efficient additive as a flame retardant which decreases the amounts of additives in products and improves their efficiency. …”
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Dynamic model of a harvester equipped with a rope anchor system during logging operations on a steep slope by Lagerev A.V., Lagerev I.A., Makulina A.V.

“…The dynamic mathematical model of such a six-component system includes 35 generalized coordinates that determine the linear and angular displacements of the mass centers of the listed system components. …”
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