Preparation and in vitro evaluation of platelet membrane biomimetic liposomes loaded with vincristine sulfate by XIAO Jing, YOU Xunyi, ZHANG Along, ZHONG Rui, LIU Jiaxin, CAO Ye, WANG Hong

“…[Objective] To prepare platelet membrane biomimetic liposomes loaded with vincristine sulfate (VCR) for targeted delivery to tumor. [Methods] Vincristine sulfate liposomes (LIPO) were prepared using the pH-gradient method, followed by the fusion of platelet membranes and subsequent drug loading to obtain platelet membrane biomimetic liposomes (PLM-LIPO). …”
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Benzimidazole resistance-associated mutations improve the in silico dimerization of hookworm tubulin: An additional resistance mechanism by Jan Clyden B. Tenorio, Muhammad Fikri Heikal, Alok Kafle, Prasert Saichua, Sutas Suttiprapa

“…Background and Aim: Mutations in the β-tubulin genes of helminths confer benzimidazole (BZ) resistance by reducing the drug’s binding efficiency to the expressed protein. However, the effects of these resistance-associated mutations on tubulin dimer formation in soil-transmitted helminths remain unknown. …”
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Characteristics of the source material for breeding winter wheat for group resistance to leaf and stem pathogens by Є. А. Голуб, Н. І. Сауляк, О. А. Васильєв, М. А. Литвиненко, В. А. Трасковецька, З. В. Щербина, М. А. Бушулян, Є. І. Кірчук

“…Investigation of the efficiency of using introgressive lines with group resistance to leaf pathogens as source material in breeding winter wheat (Triticum aestivum L.) for the aforementioned trait. …”
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Ultrasonication-mediated synthesis of diblock polymer-based nanoparticles for advanced drug delivery systems: Insights and optimization by Nagaraja Sreeharsha, Srikruthi Kunigal Sridhar, Asha Bhuvanahalli Rangappa, Prakash Goudanavar, Purushotham Karadigere Nagaraju, Nimbagal Raghavendra Naveen, Predeepkumar Narayanappa Shiroorkar, Afzal Haq Asif, Girish Meravanige, Krishna Swaroop Duddi Sreehari

“…Optimization of SLNs formulation was achieved through a systematic approach, utilizing response surface methodology, optimal conditions for SLNs synthesis were determined, resulting in nanoparticles with a particle size of 198 nm and an entrapment efficiency of 67.42 %. …”
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Nose-to-Brain Delivery of Chitosan-Grafted Leciplexes for Promoting the Bioavailability and Antidepressant Efficacy of Mirtazapine: In Vitro Assessment and Animal Studies by Amani M. El Sisi, Essam M. Eissa, Ahmed H. E. Hassan, Marina A. Bekhet, Fatma I. Abo El-Ela, Eun Joo Roh, Rasha M. Kharshoum, Adel A. Ali

“…Then, the determined optimum formulation was coated with chitosan (CS-MRZ-LPX) and utilized in pharmacodynamics investigations and in vivo biologic distribution studies in Wistar male rats. …”
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Calibration of Short-Wave Infrared Spectrometer for Atmosphere Methane Monitoring by Haoran Li, Fuqi Si, Liang Xi, Fang Lin, Yu Jiang, Fenglei Liu, Yi Zeng, Yunkun Han, Kaili Wu

“…This study proposes spectral and radiometric calibration methods for the characteristics of the spectrometer, such as the small-area array, high signal-to-noise ratio, and high spectral resolution. …”
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TECHNICAL-TECHNOLOGICAL AND SOCIAL TECHNIQUES OF FOOD SAFETY PROVISION IN CUSTOMS UNION COUNTRIES by V. A. Alyoshina

“…Results: Basing on analytical data and expert estimations, the author grounds the technique of designing the profile of food safety of a state enabling to multilaterally characterize the influence of external and internal factors, to make conclusions concerning the dynamics of food safety indicators and to give recommendations on elimination of the revealed negative trends, as well as to determine the integral safety level. Scientific novelty: economic-mathematical methods are applied to specify the food saefety indicators, the technical-technological aspect and social factors determining the food safety of the region are described, the technique of designing and characterizing the economical safety profile is tested on the example of Customs Union countries. …”
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Hybrid Electrocoagulation–Adsorption Process for Montelukast Sodium Removal from Water by Sayedali Mirkhalafi, Khalid S. Hashim, Osamah Al-Hashimi, Ali Majdi

“…Finally, the combined EC-A process, with the pH of residual water adjusted to 3, further enhanced the removal efficiency to 74%, highlighting the method’s potential for pharmaceutical contaminant removal. …”
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Ethical Challenges and Opportunities of AI in End-of-Life Palliative Care: Integrative Review by Abel García Abejas, David Geraldes Santos, Fabio Leite Costa, Aida Cordero Botejara, Helder Mota-Filipe, Àngels Salvador Vergés

“…While AI shows promise for improving efficiency and personalization, consolidated real-world examples of efficiency and equity remain scarce. …”
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Evaluation of The Hydraulic and Field Performance of Center Pivot Irrigation Systems in a Semi-Arid Climate by Zechariah Jeremaiho Othong, Abdul-Ganiyu Shaibu, Abdul-Halim Abubakari

“…Aim of the study: This study aims to evaluate the hydraulic and field performance of center irrigation systems in a semi-arid climate to determine their efficiency and effectiveness in optimizing water use and crop yield in such conditions. …”
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Enhancing Nutrient-Enriched Compost through Optimized Co-Composting of Sugarcane Bagasse in Tropical Environments by Suraj Asava, Dayanand Sharma, Chandrashekhar Parab, Rajnikant Prasad, Kunwar D. Yadav

“…Material proportions were adjusted (Trial-1-3 and Control), and small bins were utilized to determine the ideal mix ratio. Monitoring over 56 days evaluated composting efficiency. …”
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Homogeneous and Heterogeneous Photo-Fenton-Based Photocatalytic Techniques for the Degradation of Nile Blue Dye by Georgia Papadopoulou, Eleni Evgenidou, Dimitra Lambropoulou

“…Similarly, increasing the oxidant concentration accelerated the reaction rate up to an optimal level, beyond which radical scavenging effects were observed, reducing the overall efficiency. In contrast, heterogeneous systems exhibited negligible degradation in the absence of an oxidant; however, the addition of oxidants significantly improved the process efficiency. …”
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Modelling of the Elasticity Modulus for Rock Using Genetic Expression Programming by Umit Atici

“…This study reports a new and efficient approach to the formulation of the static modulus of elasticity Es applying gene expression programming (GEP) with nondestructive testing (NDT) methods. …”
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A Novel CTC-Binding Probe: Enzymatic vs. Shear Stress-Based Detachment Approaches by Sophia Krakowski, Sara Campos, Henri Wolff, Gabi Bondzio, Felix Hehnen, Michael Lommel, Ulrich Kertzscher, Paul Friedrich Geus

“…In the context of cancer, circulating tumor cells (CTC) can be used as biomarkers to determine the nature of the tumor, its stage of progression, and the efficiency of the administered therapy through monitoring. …”
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Modern strategies for study of tumor’s markers in clinical practic by I. B. Zborovskaya

“…Essentially new capacities of clinical oncology are uncovered with the help of modern molecular biology methods that allow to determine structural and functional changes of genes and their products. …”
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Advanced Defect Detection on Curved Aeronautical Surfaces Through Infrared Imaging and Deep Learning by Leith Bounenni, Mohamed Arbane, Clemente Ibarra-Castanedo, Yacine Yaddaden, Sreedhar Unnikrishnakurup, Andrew Ngo Chun Yong, Xavier Maldague

“…Detecting defects on aerospace surfaces is critical to ensure safety and maintain the integrity of aircraft structures. Traditional methods often need more precision and efficiency for effective defect detection. …”
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Innovative approaches to optimizing taxation in organizations by E. A. Kirova, E. A. Ponomarenko

“…The use of innovative approaches in the process allows to increase efficiency and reduce tax expenses. In addition, innovative methods and technologies implementation can reduce time for tax optimization, simplify tax reporting monitoring and analysis, and improve decisions quality. …”
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Evaluating the level of digitalization of the innovation process with artificial intelligence approach in the digital transformation of knowledge-based companies by ali Bagheri, reza radfar, sepehr ghazinoory

“…The results of 188 indicators were distributed in the form of a 5-point Likert questionnaire and by Delphi method in two times among 18 experts in this field. …”
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Methodology for forecasting average long-term damage in the economic justification of flood protection measures by Andrey V. Shalikovsky, Sergey G. Kosarev, Konstantin A. Kurganovich, Maxim A. Bosov, Alla V. Maslova, Evgenia Kh. Zykova, Alexey A. Solodukhin, Denis V. Kochev

“…An increase in damage from floods suggests the need to implement economically sound preventive measures, but currently in Russia, there are no approved methods for calculating the economic efficiency of water management measures. …”

The Effect of Processing of Hempseed on Protein Recovery and Emulsification Properties by Anne Pihlanto, Markus Nurmi, Nora Pap, Jarkko Mäkinen, Sari Mäkinen

“…In conclusion, germination and peeling in combination with defatting are promising methods to produce functional protein concentrates with efficient emulsion stability and activity as well as a mild colour for food applications.…”
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