High INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): protocol for a multicentre, proof-of-concept, prospective interventional study by Gordon McGregor, Chao Huang, Maureen Twiddy, Judith Long, Amy Harwood, Lee Ingle, Saïd Ibeggazene, Sean Pymer, Adam R Nicholls, Sean Carroll, Marjorie Rooms, I C Chetter

“…High-intensity interval training (HIIT) is more time-efficient and therefore has the potential to overcome this barrier. …”
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Scanning by DOVAM-S Detects All Unique Sequence Changes in Blinded Analyses: Evidence that the Scanning Conditions Are Generic by C.H. Buzin, C.Y. Wen, V.Q. Nguyen, G. Nozari, A. Mengos, X. Li, J.S. Chen, Q. Liu, R.A. Gatti, F.K. Fujimura, S.S. Sommer

“…Blinded analyses that detect 400 unique sequence changes are required to determine that a scanning method detects at least 98.5% of mutations.…”
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Electrocatalytic and photocatalytic activities of two alkynyl Ag20 cage clusters involved ligand exchange between PhCOO− and CF3COO− by Yi-Fan Tan, Li Li, Kun Zhou, Guang-Min Liang, Jing Sun, Jiu-Yu Ji, Yan-Feng Bi

“…Two silver alkynyl clusters, [(CO32−)@Ag20(tBuC≡C)14(PhCOO)3(CF3COO)] (1) and [(CO32−)@Ag20(tBuC≡C)14(PhCOO)(CF3COO)3] (2), composed of alkynyl Ag20 shell templated by a CO32− anion and supported by carboxyl ligands PhCOO− and CF3COO−, were synthesized successfully by conventional methods. Single crystal X–ray diffractometer (SCXRD) was used to determine the precise structures of 1 and 2. …”
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Gaining Insight into Operative Performance: Analysis of an Automated 360-Degree Feedback Tool Among Perioperative Staff by Stefanie J. Soelling, MD, MPH, Robert D. Sinyard, MD, Lauren Spigel, MPH, Max Riley, MD, Paul Gregory, PhD, Nick Perdomo, MS, Yves Sonnay, MScPH, Steven Yule, PhD, Steven J. Fishman, MD, Douglas S. Smink, MD, MPH, FACS

“…Combined inductive and deductive coding was used to determine their perceptions regarding the utility of and barriers to the i360. …”
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Targeting atrial fibrillation in HFpEF: the emerging role of pulsed field ablation by A. S. Parwani, A. S. Parwani, A. S. Parwani, B. Kossmann, B. Kossmann, V. Schweiger, V. Schweiger, V. Schweiger

“…As PFA gains traction for its procedural efficiency and favorable safety profile, its role in managing AF in HFpEF may expand. …”
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Enhancing Marshall stability of asphalt concrete using a hybrid deep neural network and ensemble learning by Henok Desalegn Shikur, Ming-Der Yang, Yared Bitew Kebede

“…Accurate prediction of Marshall Stability (MS) is vital for asphalt concrete mix design and performance evaluation, yet traditional laboratory methods are resource-intensive. This study proposes and evaluates hybrid machine learning models, specifically integrating a deep neural network (DNN) base learner with various ensemble techniques (Random Forest, XGBoost, LightGBM, CatBoost, AdaBoost) through stacking, to enhance the accuracy and efficiency of MS prediction. …”
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LINC00662 regulates osteogenic differentiation of BMSCs and inhibits fracture healing via miR-330-3p/PTEN axis by Jiawei Gong, Jiehua Luo, Teng Zeng, Liping Zhu, Huasong Luo, Kun Ding, Mohamed Lamin Bangura, Jinliang Ma, Yunfeng Lv

“…This study nvestigates the molecular mechanism underlying fracture healing to identify improved therapeutic strategies. Methods Serum samples were collected from 76 normal fracture healing (NFH) and 70 DFH patients. …”
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Approach to Selenium Application in Different Soil Concentrations for Encouraged Yield, Distribution, and Biofortification of Common Buckwheat Seeds (<i>Fagopyrum esculentum</i> Mo... by Alexandra Zapletalová, Marek Kolenčík, Ladislav Ducsay, Mária Vicianová, Tomáš Vician, Ivan Černý, Rastislav Bušo

“…Following manual harvesting, chemical analysis was conducted using methods such as atomic absorption spectroscopy (AAS) and inductively coupled plasma mass spectrometry (ICP-MS), along with yield determination. …”
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Carbon footprint reduction associated with a surgical outreach clinic by David Forner, Chad Purcell, Victoria Taylor, Christopher W. Noel, Larry Pan, Matthew H. Rigby, Martin Corsten, Jonathan R. Trites, Antoine Eskander, Ted McDonald, S. Mark Taylor

“…Canadian datasets of manufacturer provided vehicular efficiency were used to estimate carbon emissions for each participant. …”
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Cutting-edge approaches to specific energy prediction in TBM disc cutters: Integrating COSSA-RF model with three interpretative techniques by Jian Zhou, Zijian Liu, Chuanqi Li, Kun Du, Haiqing Yang

“…Specific energy (SE) is an important index to measure crushing efficiency in mechanized tunnel excavation. Accurate prediction of the SE of tunnel boring machine disc cutters is important for optimizing the crushing process, reducing energy consumption, and minimizing machine wear. …”
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Th1 and Th2 cytokine response of peripheral blood macrophages-lymphocyte co-culture on challenge with Bacillus Calmette-Guérin and Mycobacterium tuberculosis H37RV in different cat... by Surangana Saha, Urmita Chakraborty, Avranil Goswami, Nishith Kumar Pal

“…Background: The quantitative analysis of Th1 and Th2 cytokines by in vitro challenged macrophages from tuberculosis (TB) patients of different clinical setting and healthy controls would enlighten our knowledge of macrophage efficiency at different ages and status of disease, facilitating new treatment feasibility by immunotherapy. …”
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Utility of CA-125 for diagnosis and prognosis of breast cancer: a systematic review by Zohre Momenimovahed, Afrooz Mazidimoradi, Leila Allahqoli, Zohre Khalajinia, Hamid Salehiniya, Ibrahim Alkatout

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The diagnostic accuracy of point-of-care nucleic acid-based isothermal amplification assays for scrub typhus: a systematic review and meta-analysis by Rashi Dixit, Sandeep Manikandan, John Antony Jude Prakash, Manisha Biswal, Dharitri Mohapatra, Natarajan Gopalan, G. Gnanamani, Sujit Kumar Behera

“…Using the methodology of systematic reviewing and meta-analysis, the study aimed to synthesize and compare the diagnostic performances of all the available isothermal assays for the detection of classical rickettsial diseases.MethodsStudies were retrieved from PubMed and Scopus, and selection and screening were conducted using pre-determined inclusion and exclusion criteria. …”
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Design, spectroscopic analysis, DFT calculations, adsorption evaluation, molecular docking, comprehensive in silico and in vitro bioactivity studies of thiocarbohydrazide grafted d... by Magda A. Akl, Aya G. Mostafa, Abdelrahman S. El-Zeny, El-Sayed R. H. El-Gharkawy

“…The adsorption process was determined to be exothermic and spontaneous across varying temperatures. …”
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Automated sleep staging model for older adults based on CWT and deep learning by Qunfeng Niu, Ranran Gui, Hengfang Liu, Liuyi Li, Lei Shi, Kunming Jia, Peng Li, Li Wang

“…To further validate the superiority of the RICM-SleepNet model, this study compared it with recent research methods that have demonstrated good performance in sleep staging. …”
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Analysis of Irrigation, Crop Growth and Physiological Information in Substrate Cultivation Using an Intelligent Weighing System by Jiu Xu, Lili Zhangzhong, Peng Lu, Yihan Wang, Qian Zhao, Youli Li, Lichun Wang

“…Compared to traditional estimation methods, the MAE and RMSE decreased by 12.5% and 15.0%, respectively. …”
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Inhibition of Aspartate &amp;beta;-Hydroxylase Enhances Anti-Tumor Immunity by Johari SD, Krausova K, Zucha B, Madureira Trufen CE, Polakova I, Olsen M, Smahel M

“…Different types of lymphoid and myeloid cells were likely involved in the activated immune response that was efficient against tumors with MHC-I downregulation, which are often resistant to T-cell-based therapies. …”
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Diagnostics-linked Antimicrobial Surveillance: A Route to Patient-Centred Microbiology Diagnostics? by Dr Alex Howard, Dr Charlotte Brookfield, Dr Conor Rosato, Dr Anoop Velluva, Dr Alessandro Gerada, Professor William Hope

“…However, the provision of efficient and effective microbiology diagnostics is hampered by a poor understanding of the impact of microbiology tests on antimicrobial treatment in real-world settings – this is partly due to antimicrobial treatment surveillance and datasets being detached from antimicrobial diagnostic surveillance, particularly in resource-restricted global settings. …”
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Dynamic Mechanical and Charlesby-Pinner Analyses of Radiation Cross-Linked Ethylene-Vinyl Acetate Copolymer (EVA) by Anna Svarcova, Petr Svoboda

“…Due to a higher VA content (12 wt.%), EVA 212 exhibits more efficient network formation.…”
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Estimating Spatiotemporal Dynamics of Carbon Storage in <i>Roinia pseudoacacia</i> Plantations in the Caijiachuan Watershed Using Sample Plots and Uncrewed Aerial Vehicle-Borne Las... by Yawei Hu, Ruoxiu Sun, Miaomiao He, Jiongchang Zhao, Yang Li, Shengze Huang, Jianjun Zhang

“…Compared to traditional methods based on diameter at breast height (DBH), carbon storage assessments demonstrated superior accuracy and scientific validity. …”
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