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8521
7aaRGD - a novel SPP1/integrin signaling-blocking peptide reverses immunosuppression and improves anti-PD-1 immunotherapy outcomes in experimental gliomas
Published 2025-04-01“…We hypothesized that a combination strategy aiming to block the reprogramming of GAMs using a synthetic 7aaRGD peptide that targets SPP1/integrin signaling might overcome resistance to ICIs and reinvigorate anti-tumor immunity. Methods Matrigel invasion assay was used to test the efficacy of 7aaRGD in glioma-microglia co-cultures. …”
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8522
Combined exercise training and dietary interventions versus independent effect of exercise on ectopic fat in individuals with overweight and obesity: a systematic review, meta‐anal...
Published 2025-12-01“…Therefore, the objective of this study was to investigate the effects of diet-only, and combined diet-plus-exercise interventions versus exercise only on ectopic fat reduction, and weight loss in adults with overweight or obesity.Methods Web of Science, PubMed, and Scopus were searched for original articles, published until 1 March 2024 (no limitation on publication dates) that included diet only/or exercise and diet versus exercise alone on body weight, and ectopic fat in adults with overweight or obesity. …”
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8523
Recuperação de solos afetados por sais pela aplicação de gesso de jazida e calcário no Nordeste do Brasil Reclamation of salt-affected soils in Northeast Brazil with application of...
Published 2004-04-01“…In the saturation extract the electrical conductivity and the soluble cations were determined. The application of gypsum and the mixture of gypsum + limestone showed to be efficient for correction of soil sodicity, which was indicated by a positive effect on the physical and chemical characteristics of the soils, therefore these may be recommended as calcium source for the reclamation of the saline-sodic soils. …”
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8524
Investigating the relationship between the monetary policy shock through the exchange rate channel on the management quality index in the banking system: by examining the productiv...
Published 2025-03-01“…The current research is applied in terms of its purpose and analytical-descriptive in terms of its method. This study utilizes 96 variables of seasonal time series data that affect the management quality index within the bank productivity framework, one of the critical indicators for assessing the health of the banking system. …”
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8525
In Vitro Effect of Ferruginol, Tanshinone, and Carnosol Analogues on the Proliferation of Three Breast Cancer Cell Lines
Published 2025-06-01“…The compounds that were synthesized underwent a methodical evaluation using multiple biological tests (including viability assays, clonogenic assays, and mitochondrial membrane polarization measurements) to determine their ability to inhibit in vitro the growth of three breast cancer cell linages. …”
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8526
Automated synthesis of technological fixture constructions
Published 2019-12-01“…Automated synthesis of fixtures is considered in this article. A method for determining the design situation is proposed. …”
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8527
Virtual Physical Education: Google Meet as an alternative platform for learning skill-based concepts
Published 2022-11-01“…Also, a full collinearity assessment on the outer model was performed to determine if the model is free from Common Method Bias. …”
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8528
Anisotropic temperature-dependent lattice parameters and elastic constants from first principles
Published 2025-08-01“…By replacing the costly multidimensional minimization with a gradient-based method that leverages second-order derivatives of the vibrational free energy, the number of required phonon band structure calculations is significantly reduced: only six are needed for hexagonal, trigonal, and tetragonal systems, and 10–28 for lower-symmetry systems to determine the temperature dependence of lattice parameters and thermal expansion. …”
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8529
Computer-measuring system of the induction motor’s dynamical torque-speed characteristics
Published 2019-06-01“… In the article an efficient method of determining the dynamic torque-speed characteristic of induction motors and the computer-measuring system for its realization is considered. …”
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8530
Unsupervised clustering of temporal patterns in high-dimensional neuronal ensembles using a novel dissimilarity measure.
Published 2018-07-01“…SPOTDisClust does not require binning and can detect complex patterns (beyond sequential activation) even when high levels of out-of-pattern "noise" spiking are present. Our method handles efficiently the additional information from increasingly large neuronal ensembles and can detect a number of patterns that far exceeds the number of recorded neurons. …”
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8531
Human Resource Information System with Machine Learning Integration
Published 2022-06-01“…Based on the thorough evaluation of the experts and respondents, it was found that the human resource information system is highly usable, secured, efficient, and provides a fast and easy way to manage employees' records and predict employees over using a supervised machine learning that uses the linear regression method. …”
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8532
A Cooperative Trajectory Optimization Algorithm for Connected Vehicles in Merging Zones
Published 2022-01-01“…Numerical experiments validate that the proposed method guarantees safe driving and provides relatively smooth trajectories to the vehicles. …”
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8533
Optimization Design and Experimental Verification of Type B Bogie Frame Structure Based on Workbench
Published 2019-07-01“…At the same time, the method was more efficient and more accurate than the optimal design based on experience, which could provide reference for the optimization design of other rail vehicle structures.…”
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8534
AHP-Guided Stacked Ensemble Modeling for Student Engagement Level Prediction in Online Education
Published 2025-01-01“…Second, the use of a novel feature selection method based on Analytic Hierarchy Process (AHP) and an iterative approach. …”
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8535
Gastropod and Bivalvia Diversity Using Environmental DNA (E-DNA) Techniques in The Waters of Gili Genting and Gili Labak Islands, Sumenep, Madura
Published 2025-01-01“…The method used in this study is the environmental DNA method to detect species through air samples, because it is considered an effective and efficient method. …”
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8536
Integral Approach in Discourse Studies (Voice Messaging Study)
Published 2023-11-01“…Discursive analysis and the sociological survey method are used to describe the nature of the voice message. …”
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8537
Transient stability improvement of a transmission system through the application of an artificial neural network-based high-voltage direct current system
Published 2025-07-01“…The Newton–Raphson power flow method is employed to determine the base-case characteristics of the network. …”
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8538
The unintended outcome: a retrospective cross‐sectional study using a urine lateral flow assay to detect ART use reveals non‐disclosure of taking ART in South Africa's public healt...
Published 2025-06-01“…CD4 counts were determined at the time of ART initiation, per national guidelines. …”
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8539
Investigating waste management strategies in the extended producer responsibility in Iran
Published 2020-12-01“…The present paper seeks to implement the responsibility of producers to manage waste from the consumption of goods in Iran. Material and methods: In this research, using a questionnaire, the opinions of 60 experts and domestic experts in the field of research were used. …”
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8540
Retrospective antimicrobial consumption surveillance at health facility level in Dodoma Region, Tanzania
Published 2025-05-01“…This study presents a robust method for monitoring AMC and resistance in a resource-efficient manner, offering potential applicability in similar settings across SSA. …”
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