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6501
Multi-Strategy Fusion Path Planning Algorithm for Autonomous Surface Vessels with Dynamic Obstacles
Published 2025-07-01“…Consequently, this study introduces a path planning algorithm for autonomous surface vessels (ASVs) that integrates an improved fast marching method (FMM) with the dynamic window approach (DWA) for underactuated ASVs. …”
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6502
Repositioning Small and Medium Scale Enterprises for Growth: Focus on Rural Women Entrepreneurs in Abia State, Nigeria
Published 2022-12-01“…This paper assessed the ways in which rural women SMEs can be repositioned for maximum growth, based on two objectives: to examine the factors that affect rural women SMEs; and to ascertain the determinants of growth of rural women SMEs. The paper utilized survey research method, and deployed a structured questionnaire based on the 5-point Likert scale. 250 participants were drawn for the study, while face and content validity techniques were employed. …”
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6503
Organization of Production and Business Processes in Value Chains Based on Applied Scenarios for the Digitalization of Enterprises
Published 2023-07-01“…The implementation of end-to-end digital technologies into the economic activities of enterprises radically changes the organization of production and business processes within the framework of more efficient business models. As a result, new application scenarios are formed that determine the changing structure of production and business processes and the emergence of new roles of participants in the value chain. …”
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6504
Pharmacoeconomic aspects of the targeted drugs use in psoriatic arthritis in context of the Russian healthcare system
Published 2022-10-01“…Objective: to study the clinical and economic aspects of the use of biological disease modifying antirheumatic drugs (bDMARDs) and targeted synthetic DMARDs (tsDMARDs), Janus kinase inhibitors (JAKi), for the treatment of psoriatic arthritis (PsA).Patients and methods. The study included adult patients (age ≥18) with active PsA, bionaive or previously treated with bDMARDs. …”
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6505
The effectiveness of cardiac resynchronization therapy in patients with chronic heart failure of various origin depending on the structural myocardial injury in cardiac magnetic re...
Published 2019-12-01“…To assess the effect of the size and pattern of myocardial structural injury, determined by magnetic resonance imaging (MRI), on response to cardiac resynchronization therapy (CRT) in patients with ischemic and non-ischemic heart failure (HF).Material and methods. …”
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6506
AI-Based Noise-Reduction Filter for Whole-Body Planar Bone Scintigraphy Reliably Improves Low-Count Images
Published 2024-11-01“…<b>Methods</b>: The performance of the AI bone-scan filter (BS-AI filter) in question was retrospectively evaluated on 47 different patients’ <sup>99m</sup>Tc-MDP bone scintigraphy image pairs (anterior- and posterior-view images), which were obtained in such a manner as to represent the diverse characteristics of the general patient population. …”
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6507
CircRNA-miRNA-mRNA networks in plasma extracellular vesicles as biomarkers for first-onset schizophrenia
Published 2025-07-01“…Here, we constructed circRNA-miRNA-mRNA networks of EVs, and examined their diagnostic efficiency in FOS. Methods The expression levels of circRNAs, miRNAs and mRNAs in EVs derived from 10 FOS patients and 10 healthy controls (HC) were determined by high-throughput sequencing. …”
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6508
Uptake of DU145 and LNCaP prostate cancer cell line derived extracellular vesicles is inversely correlated with blood–brain barrier integrity in vitro
Published 2025-07-01“…This study investigated the interaction and effects of sEVs derived from low (LNCaP) and moderately metastatic (DU145) prostate cancer (PCa) cell lines with the human brain endothelial cell line hCMEC/D3. Methods Systematic optimization of the cell culture membrane insert set-up for sEV transport studies was accomplished with inserts with different pore sizes, varied coating procedures and medium compositions. …”
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6509
Qualitative assessment of Shiraz wastewater treatment plant effluent for different purposes
Published 2023-06-01“…In this regard, at first, the values of various physical and chemical parameters such as acidity, electrical conductivity, total dissolved solids, total suspended solids, total volatile solids, total solids, chemical oxygen demand, biochemical oxygen demand, turbidity, dissolved oxygen, detergents, phosphate, total phosphorus, nitrate, nitrite, ammonia, Kjeldahl total nitrogen, free chlorine, and fat-oil-grease were determined in raw and treated wastewater. Then, while comparing the values of these parameters with the standard of the Environmental Protection Organization of Iran, the removal efficiencies of these parameters were calculated and finally, the quality of the effluent was investigated for use in various sectors.Results and discussion: The results showed that the removal efficiency of BOD5, COD, TSS, NH3, detergents, and fat-oil-grease in this treatment plant is 85, 85, 67, 64, 94, and 68.5%, respectively. …”
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6510
Exploring the clinical value of procalcitonin, c-reactive protein, white blood cell count, and neutrophil-to-lymphocyte ratio in the early diagnosis of bloodstream infections in ch...
Published 2025-01-01“…Therefore, we investigated the clinical value of procalcitonin (PCT), C-reactive protein (CRP), white blood cell count (WBC), and neutrophil-to-lymphocyte ratio (NLR) in the early diagnosis of BSI in children. Methods This study included a retrospective analysis of 309 suspected BSI cases and patients were categorized into 2 groups based on blood culture results: blood culture-positive group, and blood culture-negative group. …”
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6511
Experience with long-term infliximab therapy in patients with ankylosing spondylitis
Published 2010-12-01“…The duration of continuous use of infliximab is more than 8 years in patients with ankylosing spondylitis (AS). The efficiency of the drug persists in most patients during its long-term regular therapy. …”
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6512
INVESTIGATION OF IMMUNOGENICITY AND SAFETY OF 23-VALENT POLYSACCHARIDE PNEUMOCOCCAL VACCINE IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS
Published 2018-09-01“…Objective: to investigate the safety and immunogenicity of 23-valent polysaccharide pneumococcal vaccine (PPV-23) in patients with systemic lupus erythematosus (SLE). Subjects and methods. The investigation enrolled 30 patients with a reliable diagnosis of SLE; of them there were 27 women and 3 men at the age of 19 to 62 years. …”
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6513
Myocardial work in electrical dyssynchrony due to left bundle branch block
Published 2025-03-01“…To evaluate myocardial function in different groups of patients with left bundle branch block (LBBB) and the LBBB "model" — right ventricular pacing (RVP).Material and methods. Global longitudinal strain (GLS) and myocardial function parameters, such as global constructive work (GCW), global wasted work (GWW), global work index (GWI), and global work efficiency (GWE), were measured in 25 patients with dilated cardiomyopathy (DCM) and LBBB (DCM-LBBB group), 20 patients with DCM and a narrow QRS complex (DCM-nonLBBB group), 15 patients with LBBB developed after transcatheter aortic valve implantation (TAVI LBBB group), 12 patients with idiopathic LBBB (I-LBBB group), 27 patients with permanent RVP, and 10 healthy volunteers (HVs). …”
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6514
Transmucosal Delivery of miR-30c-5p by Chitosan Nanoparticles for Oral Squamous Cell Carcinoma
Published 2025-07-01“…To address these issues, miR-30c-5p was encapsulated into chitosan nanoparticles (CS-NPs) using ionic gelation to enhance delivery and protect against degradation.Methods: miR-30c-5p-loaded CS-NPs were characterized for particle size, zeta potential, morphology, and encapsulation efficiency. …”
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6515
Robot-assisted laparoscopic ureteropelvic junction plasty in children using the da Vinci Xi robotic system: a Russian first experience
Published 2025-06-01“…To conduct a comprehensive analysis of the experience in performing RALP in pediatric patients using the da Vinci Xi robotic platform. Materials & methods. Between July and October 2024, a total of 14 robot-assisted laparoscopic pyeloplasties (RALP) were successfully performed. …”
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6516
CHANGES OF CYTOKINE LEVELS DURING THERAPY WITH METHOTREXATE AND ADALIMUMAB IN PATIENTS WITH EARLY RHEUMATOID ARTHRITIS (REMARCA STUDY)
Published 2014-06-01“…Objective: to estimate changes in cytokine profile versus disease activity in patients with early rheumatoid arthritis (RA) who use methotrexate (MTX) and adalimumab (ADA) in accordance with the treat-to-target concept. Subjects and methods. Forty-five patients (35 women; median age 53.5 [46; 59.5] years) with early RA (median dura- tion 7.0 [4.0; 11.5] months; DAS28 5.8 [4.9; 6.4]; rheumatoid factor positivity (RF+) 91%; anti-cyclic citrullinated peptide antibody positivity (ACCP) + 96%) were examined. …”
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6517
AN EVALUATION OF FACTORS AFFECTING THE SELECTION OF MEDICAL SPECIALTIES
Published 2021-01-01“…Background: Coherence between the manpower needs in healthcare and factors which determine the specialization preferences of medical faculty students (MFS) is very important for efficiency. …”
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6518
Real Time Estimation of the Wind Speed Components Based on Measurement Data from Satellite Navigationand Barometric Measurements
Published 2024-12-01“…By integrating these diverse sources of information, the proposed algorithm using parametric identification method achieves remarkable accuracy in determining the crucial parameters, i.e. wind speed components, necessary for flight operations. …”
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6519
Thermo-hydraulic performance analysis of multi-layer porous fin microchannels
Published 2025-10-01“…This study investigates the thermal performance improvements of multi-layer porous fins compared to solid and single-layer porous fins. A simulation method is utilized to determine the effects of different porous properties and height ratios on thermo-hydraulic performance. …”
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6520
The Influence of Financing, Financing Risk and Liquidity Risk on the Profitability of Private Islamic Commercial Banks (BUS) in Indonesia
Published 2025-07-01“…The study used is quantitative explanatory method. The data used are derived from annual financial reports of Private Sharia Commercial Banks. …”
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