-
6281
Smartphone-based machine learning model for real-time assessment of medical kidney biopsy
Published 2024-12-01“…In response to this challenge, we aimed to develop a machine learning model capable of assessing the percentage cortex of each biopsy pass using smartphone images of the kidney biopsy tissue at the time of biopsy. Methods: 747 kidney biopsy cores and corresponding smartphone macro images were collected from five unused deceased donor kidneys. …”
Get full text
Article -
6282
Ultrasound feature-based nomogram model for predicting extrathyroidal extension in papillary thyroid carcinoma
Published 2025-07-01“…Univariate and multivariate logistic regression analyses were used to identify independent predictors of ETE in PTC, and an ETE nomogram prediction model was constructed to predict the risk of ETE in capsule-contacting PTC. The predictive efficiency of the model was evaluated using receiver operating characteristic (ROC) curve and calibration curves, and the clinical value of the model was determined through decision curve analysis (DCA). …”
Get full text
Article -
6283
Construction and verification of the prediction model for risk of sleep disturbance in elderly patients with hypertension: a cross-sectional survey based on NHANES database from 20...
Published 2024-10-01“…Abstract Objective To construct and verify a risk prediction model for sleep disturbance in elderly patients with hypertension, aiming to offer guidance for sleep management in this demographic. Methods A cohort of 6,708 elderly hypertensive patients from the NHANES database, spanning 2005 to 2018, met the inclusion criteria and were selected for this study. …”
Get full text
Article -
6284
Preparation of Trop2-targeted chimeric antigen receptor T cells and study of their exhaustion status in vitro
Published 2025-08-01“…Objective To design and construct chimeric antigen receptor (CAR) T cells targeting Trop2, establish an in vitro cell exhaustion model through continuous antigen stimulation, and investigate their anti-tumor activity and exhaustion characteristics. Methods The second-generation CAR plasmid was constructed based on the single-chain variable fragment (scFv) sequence of Sacituzumab Govitecan targeting Trop2. …”
Get full text
Article -
6285
SC134-deruxtecan, a fucosyl-GM1 targeting ADC for small cell lung cancer therapy
Published 2025-08-01“…We have developed SC134-deruxtecan, an antibody drug conjugate (ADC) targeting FucGM1 in SCLC, and characterized its preclinical activity. Methods SC134 binding specificity and affinity were tested through enzyme-linked immunosorbent assay (ELISA), surface plasmon resonance (SPR), flow cytometry against several SCLC cell lines, and immunohistochemistry (IHC) of clinical samples and animal tissues. …”
Get full text
Article -
6286
Deflection of screen surface and spatial deformation law of screen apertures during 1 mm elastic screening
Published 2024-12-01“…To overcome the problems above, combining vibration testing and multi-flexible body dynamics simulation methods, the kinematic characteristics of elastic screen surface and 1 mm elastic screening test were carried out. …”
Get full text
Article -
6287
ANTIHYPERTENSIVE TREATMENT WITH COMBINED DRUG OF LOSARTAN AND HYDROCHLOROTHIAZIDE
Published 2016-01-01“…Material and methods: 30 patients with AH of I-III grade (13 men and 17 women aged 51.9±1.9) were observed. …”
Get full text
Article -
6288
Identification of Interannual Variation Frequency of Cropland Cropping Intensity Based on Remote Sensing Spatiotemporal Fusion and Crop Phenological Rhythm: A Case Study of Zhenjia...
Published 2025-05-01“…To fill this knowledge gap, this study took Zhenjiang City, Jiangsu Province, as a case study and proposed a method to determine the distribution and spatiotemporal change frequency of single- and double-season cropping patterns using spatiotemporal fusion and crop phenological rhythm. …”
Get full text
Article -
6289
Visible-light deep reduction of low concentration CO2 over composite catalyst Ru/CoAl-LDH and the performance enhancement mechanism
Published 2025-02-01“…Cobalt-aluminum layered double hydroxide (CoAl−LDH) was firstly prepared by coprecipitation-hydrothermal method and visible-light catalysts Ru/CoAl-LDH were constructed by loading ruthenium nanoparticles onto the surface of CoAl-LDH via surface impregnation coupled with hydrogen heat treatment. …”
Get full text
Article -
6290
Study on the Influence of MnO2 Crystal Phases on Low-Temperature Microwave Catalytic Mineralization of Toluene
Published 2025-08-01“…Four different crystalline phases of MnO2 catalysts (α-MnO2, β-MnO2, δ-MnO2, and γ-MnO2) were successfully synthesized by the hydrothermal method. The catalytic oxidation activity and microwave utilization potential of the different catalysts were evaluated quantitatively, considering both physicochemical and microwave properties. …”
Get full text
Article -
6291
HARMFUL CONDITIONS ON THE DENTAL STATUS OF POULTRY FARM WORKERS
Published 2018-03-01“…Researches evaluated hygienic indexes of working areas by laboratory method. Indicated that the dust in areas where birds are kept is mixed. …”
Get full text
Article -
6292
Constitutive modeling and workability characterization of pre-deformed AZ31 magnesium alloy during hot shear-compression deformation
Published 2025-07-01“…Pre-deformation is a cost-efficient method to control the microstructure and mechanical properties of wrought magnesium (Mg) alloys. …”
Get full text
Article -
6293
Application of Technological Solutions for Bioremediation of Soils Contaminated with Heavy Metals
Published 2021-12-01“…This article focuses on studying biotechnologies for remediation of soils contaminated with heavy metals to determine further the most effective methods for cleaning soils from the action of toxicants with their subsequent implementation in practice. …”
Get full text
Article -
6294
Confocal Laser Scanning Microscopy in Cancer Diagnosis: Current Issues and Application Outlook
Published 2021-04-01“…This non-invasive technology allows optical skin sectioning at a varying depth with no special tissue treatment or staining. This diagnostic method is currently considered the most promising in imaging and assessment of superficial skin neoplasms. …”
Get full text
Article -
6295
Design and application of hydrogen fuel cell hybrid system for digital rail vehicle
Published 2023-05-01“…For the purpose of this paper, the principle of model selection for hydrogen power and energy storage systems were summarized based on the key indicators, such as traction performance, endurance mileage and average power of digital rail vehicle, the scheme of system parameter matching and model selection that meets the actual operational requirements was determined, and an improved power following algorithm based on active following was proposed to keep the fuel cell system operates under high-efficient range during the operation of the vehicle. …”
Get full text
Article -
6296
A Cluster-Based Data Aggregation in IoT Sensor Networks Using the Firefly Optimization Algorithm
Published 2024-01-01“…The simulation outcomes, executed in MATLAB 2023b, indicated that the suggested method, the firefly optimization algorithm (FOA), outperformed the FA and LEACH in improving the quality-of-service parameters. …”
Get full text
Article -
6297
The Evaluation and Quantitation of Dihydrogen Metabolism Using Deuterium Isotope in Rats.
Published 2015-01-01“…<h4>Purpose</h4>Despite the significant interest in molecular hydrogen as an antioxidant in the last eight years, its quantitative metabolic parameters in vivo are still lacking, as is an appropriate method for determination of hydrogen effectivity in the mammalian organism under various conditions.…”
Get full text
Article -
6298
Fault complexity degree in a coal mine and the implications for risk assessment of floor water inrush
Published 2024-12-01“…A stricter meshing grade when using the box-counting method in fault complexity degree is necessary for further studies in the precise prevention and control of mine hazards.…”
Get full text
Article -
6299
Analisis Pengaruh Kualitas Layanan Terhadap Kepuasan Pelanggan dan Loyalitas Pengguna Aplikasi Jenius Menggunakan Model E-S- Qual dan E- Recs- QUal (Studi Kasus: Pengguna Aplikasi...
Published 2022-12-01“…This study uses quantitative methods using Electronic Service Quality and Electronic Recovery Service Quality models. …”
Get full text
Article -
6300
Competition Between Protein and DNA for Binding to Natural Sepiolite Nanofibers
Published 2025-03-01“…In this study, we analyzed the adsorption of DNA and proteins to sepiolite by analyzing the competition among these biomolecules during the adsorption process.Methods: To determine the binding of sepiolite to proteins, we used BSA and a monoclonal antibody (mAb) against the CD4 membrane antigen as a model. …”
Get full text
Article