Finding order in measuring disorders: Measurement Uncertainty of Thyroid Function Tests at a tertiary care hospital in Eastern India by Asis Bhattacharya, Kasturi Mukherjee, Arkajit Dasgupta, Debi Mallick, Mousumi Mukhopadhyay

“…Thyroid disorders constitute a global health menace but can be efficiently managed if diagnosed early via reliable immunoassays. …”
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COTI-2 suppresses the malignancy of bladder cancer by inducing apoptosis via the AMPK-mTOR signaling pathway by Yuancai Zheng, Keqi Wang, Chenyu Wu, Yuying Qin, Yihan Sun, Xinyu Lu, Yupeng Xu, Gonghui Li

“…Moreover, it efficiently suppressed the migration and invasion of BCa cells. …”
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Characterizing spatial epidemiology in a heterogeneous transmission landscape using the spatial transmission count statistic by Leke Lyu, Gabriella Veytsel, Guppy Stott, Spencer Fox, Cody Dailey, Lambodhar Damodaran, Kayo Fujimoto, Pamela Brown, Roger Sealy, Armand Brown, Magdy Alabady, Justin Bahl

“…Intensive and widespread efforts to collect and sequence SARS-CoV-2 viral samples have enabled the development of comparative genomic approaches to reconstruct spatial transmission history and understand viral transmission across different scales. Methods We proposed the spatial transmission count statistic that efficiently summarizes the geographic transmission patterns imprinted in viral phylogenies. …”
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Effect of Relative Isometric Strength on Countermovement Jump Performance in Professional and Semi-Professional Soccer Players by Nicholas Joel Ripley, Jack Fahey, Nabil Hassim, Paul Comfort

“…Stronger players performed the CMJ more efficiently when observing the mRSI, with a shorter time to take off, while producing greater average relative forces during the braking phase. …”
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Development and validation of an EHR-based risk prediction model for geriatric patients undergoing urgent and emergency surgery by Edward N. Yap, Jie Huang, Joshua Chiu, Robert W. Chang, Bradley Cohn, Judith C. F. Hwang, Mary Reed

“…EHR implementation of this model could efficiently support clinicians’ surgical risk assessment and perioperative decision-making discussions in this vulnerable patient population.…”
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Impact of Bobath Based Rehabilitation Program and Conventional Physiotherapy: Children with Hydrocephalus by Tanpreet Kaur Bakshi, Jaspreet Singh Vij, Ashish Chhabra

“…Materials and methods. The study design was quasi experimental in nature. …”
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Segmentation of the target audience of paid educational programs at children’s school of art: Problems and current management decisions by Natal'ya V. Litvinova

“…Segmentation of the potential audience allows you to quickly and efficiently achieve some of the goals of the institution - image enhancement, customer satisfaction, customer loyalty.The general issues of audience segmentation are well presented in the scientific literature, the topic is analyzed for preschool education of children. …”
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Evaluation of a Bayesian Belief Network tool for translating science and informing policy: the case of antibiotic misuse in Tanzania by Miss Madeleine Clarkson, Dr Katherine L Keenan, Dr Edward Lavender, Prof Stephen E Mshana, Dr Martha F Mushi, Prof Matthew TG Holden, Dr V Anne Smith

“…To assess BNNs’ capacity to live up to this promise, we make a previously derived BBN for antibiotic misuse into a web-based interactive tool and evaluated it with non-specialists. Methods: A BBN of determinants of antibiotic misuse in Tanzanian urinary tract infection patients was incorporated into a web-based application, which included an interactive tool plus other relevant information, such as educational materials. …”
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Development of scalable coastal and offshore kelp farming for marine biomass production by Michael Stekoll, Scott Lindell, Clifford A. Goudey, Hauke L. Kite‐Powell, David Bailey, Kendall Barbery, Loretta Roberson, Tamsen Peeples, Nicholas Mangini, Alf Pryor, Alexandra Meyer, Charles Yarish

“…There were three major aspects of the research: (1) optimize nursery production and seeding lines for outplanting; (2) design an economical, modular outplanting structure; and (3) develop methods to efficiently harvest the product. Farm designs were based on catenary structures and the use of spreader bars with variable spacing of grow‐lines and line types. …”
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Sea buckthorn-derived extracellular vesicles foster bone regeneration through aau-miR168-mediated pathways by Mai Zhao, Xiaolin Chen, Wenyan Wang, Mengying Li, Hui Zhang, Xiuqun Zou, Jiamin Wang, Qian Cong, Xingyuan Ma, Zhaoyuan Hou, Haodong Lin, Hao Jia

“…This study aims to elucidate the osteogenic and bone-healing properties of SAEVs. Methods SAEVs were isolated from sea buckthorn juice via differential centrifugation and characterized using electron microscopy and dynamic light scattering. …”
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Toxicity, Half-Life and Antitumor Activity of Phenyl 4-(2-Oxo-3-alkylimidazolidin-1-yl)benzenesulfonates as Novel Antimitotic CYP1A1-Targeted Prodrugs in Female Mouse Models by Atziri Corin Chavez Alvarez, Chahrazed Bouzriba, Vincent Ouellette, Mathieu Gagné-Boulet, Alexandre Patenaude, Sylvie Pilote, René C.-Gaudreault, Chantale Simard, Sébastien Fortin

“…Our screening program studies of PAIB-SO chemolibraries selected three prototypical PAIB-SOs as antimitotic prodrugs amenable for studies using BC animal models. <b>Methods</b>: Healthy female CD1^® IGS mice were treated with three prototypical PAIB-SOs, namely CEU-835, -934, and -938, for the determination of their toxicity and half-lives. …”
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Vaccine sero-monitoring and sero-surveillance of Peste des petits ruminants in small ruminants in West Gojjam zone, Amhara region, Ethiopia by Mesafint Mandefro, Saddam Mohammed Ibrahim, Demeke Sibhatu, Nebiyou Kassa, Kemal Emiyu, Kebede Debebe, Bereket Dessalegn, Mastewal Birhan, Molalegne Bitew

“…BackgroundPeste des petits ruminants (PPR) is an acute or subacute, highly contagious, and economically important, transboundary disease of small ruminants caused by Peste des petits ruminants virus (PPRV).ObjectivesThe objective of this study was to determine the seroconversion rate in PPR vaccinated flock of sheep (Sekela district) and the seroprevalence of PPRV in unvaccinated flocks of sheep and goats (Yilmanadensa district).MethodsA cross-sectional study was conducted from January to March 2022 in two selected districts of West Gojjam zone, Ethiopia. …”
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Neuro-fuzzy inference system and white shark optimization of coagulation-flocculation of aquaculture wastewater treatment by A.F. Mohamed, H. Rezk

“…Therefore, the objective of this study is determining the optimal operating condition of coagulation-flocculation through optimizing the values of the three input parameters.METHODS: Artificial intelligence and recent optimzation algorithms are integrated to achieve the purpose of this study work. …”
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Skin melanoma cells produce diverse gelsolin (GSN) isoforms, which play non-redundant roles in cells’ proliferation and motility by Ewa Mazurkiewicz-Stanek, Aleksandra Makowiecka, Iryna Kopernyk, Michał Majkowski, Anna Boguszewska-Czubara, Tomasz Trombik, Paweł Karpiński, Piotr Donizy, Antonina J. Mazur

“…Therefore, nothing is known about the role of specific GSN isoforms in skin melanoma biology. Methods We applied immunocytochemical staining to melanoma tissue samples to analyze the localization of GSN production within tumor samples. …”
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Polymer-Functionalized Magnetic Nanoparticles for Targeted Quercetin Delivery: A Potential Strategy for Colon Cancer Treatment by Júlia Borges de Macedo, Julia Narayana Schoroeder Bueno, Carla Cristine Kanunfre, José Ricardo de Arruda Miranda, Andris Figueiroa Bakuzis, Priscileila Colerato Ferrari

“…Optimized formulations had hydrodynamic diameters of 122.32 ± 8.56 nm, Zeta potentials of +30.78 ± 0.8 mV, and loading efficiencies of 80.45% (MNP-CS-Q) and 54.4% (MNP-FA-CS-Q). …”
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Simplified clinical algorithm for identifying patients eligible for immediate initiation of antiretroviral therapy for HIV (SLATE): protocol for a randomised evaluation by Mhairi Maskew, Bruce A Larson, Isaac Tsikhutsu, Margaret Bii, Peter D Ehrenkranz, Sydney Rosen, Matthew P Fox, Alana T Brennan, WD Francois Venter

“…For this policy of ‘treat all’ to succeed, millions of new patients must be initiated on ART as efficiently as possible. Studies have documented high losses of treatment-eligible patients from care before they receive their first dose of antiretrovirals (ARVs), due in part to a cumbersome, resource-intensive process for treatment initiation, requiring multiple clinic visits over a several-week period.Methods and analysis The Simplified Algorithm for Treatment Eligibility (SLATE) study is an individually randomised evaluation of a simplified clinical algorithm for clinicians to reliably determine a patient’s eligibility for immediate ART initiation without waiting for laboratory results or additional clinic visits. …”
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The effect of tactile versus auditory stimulation on reducing pain associated with invasive procedures among preterm neonates at NICUs by Entsar Shehata Mohammed, Seham Mohammed Elmwafie, Fatma Sayed Abdelaziz Mohamed, Safaa Salah Ismail

“…Abstract Background Preterm neonates often undergo invasive procedures during the period spent in neonatal intensive care units (NICUs), yet their ability to deal with pain is limited due to their immature nervous systems. Managing pain efficiently in this age is crucial, as recurrent or improperly controlled pain can have over-time influences on their neurological and physiological development. …”
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Enhanced recovery pathway for older people with hip fracture and cognitive impairment in acute hospitals: the PERFECTED research programme including an RCT by Chris Fox, Simon P Hammond, Lee Shepstone, Fiona Poland, Catherine Henderson, Tamara Backhouse, Bridget Penhale, Simon Donell, Martin Knapp, Douglas Lewins, Alasdair MacLullich, Martyn Patel, Opinder Sahota, Toby O Smith, Justin Waring, Jane L Cross

“…These data are readily available from National Hip Fracture Database and are thus ideal for efficient trial design. Client Services Receipt Inventory can be reduced for a definitive trial, removing equipment questions and some community health use questions. …”
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Merging of the Fukushima Health Management Survey With the National and Local Cancer Registry to Refine the Detection of Thyroid Cancer Cases After the 2011 Fukushima Daiichi Nucle... by Reiko Kimura‐Tsuchiya, Masanori Nagao, Shigehira Saji, Fumikazu Hayashi, Tetsuya Ohira, Hiroki Shimura, Fumihiko Furuya, Satoru Suzuki, Satoshi Suzuki, Tetsuo Ishikawa, Susumu Yokoya, Hitoshi Ohto, Seiji Yasumura

“…Methods The FHMS‐eligible residents' information was supplemented by merging and cross‐validating the FHMS and CR data using the Fukushima Prefectural Cancer Registry (FPCR), 2008–2015, and the National Cancer Registry (NCR), 2016–2018. …”
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LiDAR Sensor Parameter Augmentation and Data-Driven Influence Analysis on Deep-Learning-Based People Detection by Lukas Haas, Florian Sanne, Johann Zedelmeier, Subir Das, Thomas Zeh, Matthias Kuba, Florian Bindges, Martin Jakobi, Alexander W. Koch

“…However, to design these systems cost- and energy-efficiently, the relationship between the measurement data and final object detection output with deep neural networks (DNNs) has to be elaborated. …”
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