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9481
DIAGNOSIS OF CAROTID PARAGANGLIOMA: MULTIDISCIPLINARY ASPECTS
Published 2018-07-01“…Objective: to enhance the efficiency of diagnosis and treatment of carotid paragangliomas, by introducing of a multidisciplinary approach into clinical practice.Material and methods. …”
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9482
In Vitro Effect of Ferruginol, Tanshinone, and Carnosol Analogues on the Proliferation of Three Breast Cancer Cell Lines
Published 2025-06-01“…The compounds that were synthesized underwent a methodical evaluation using multiple biological tests (including viability assays, clonogenic assays, and mitochondrial membrane polarization measurements) to determine their ability to inhibit in vitro the growth of three breast cancer cell linages. …”
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9483
Identification and Characterization of Two Se6OMTs from <i>Stephania epigaea</i> Offer Novel Insights into the Biosynthetic Pathway of Cepharanthine
Published 2025-02-01“…Results: Two <i>O</i>-methyltransferases, Se6OMT1 and Se6OMT3, showed efficient catalytic activity at the C6 position of both (<i>R</i>)- and (<i>S</i>)-norcoclaurine. …”
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9484
Development and Validation of an Incident Hypertension Risk Prediction Model for Young Adults
Published 2025-07-01“…Conclusions Compared with the US Preventive Services Task Force, the hypertension risk prediction model may be a more efficient tool to identify high‐risk young adults for early intervention.…”
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9485
Evidence of SARS‐CoV‐2 Exposure in Cats and Dogs From Households in Romania and Long‐Term Specific Seroconversion in Cats
Published 2025-05-01“…This study aimed to evaluate the presence of SARS‐CoV‐2 specific antibodies in household dogs and cats in Romania during the COVID‐19 pandemic. Methods The study was conducted at a veterinary clinic in Iasi City, Romania, from March 2020 to December 2022. …”
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9486
Mitigation of the effect of variations in the electrical conductivity of the material via two-frequency eddy current testing of the thickness of the electrically conductive wall un...
Published 2023-03-01“… The paper analyzes feasibility of the two-frequency eddy current method for measuring the thickness of an electrically conductive wall under significantly varying test and influence parameters of the test object — the lift-off between the eddy current probe and the test object surface, and the electrical conductivity of the material. …”
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9487
Co-isolation of human donor eye cells and development of oncogene-mutated melanocytes to study uveal melanoma
Published 2025-01-01“…Conclusions We successfully isolated and established NCM, RPE, and MutCM cell lines. We describe efficient methods for the isolation and growth of NCMs and report their phenotypic, proteomic, and transcriptomic characteristics, which will facilitate the investigation of UM development and progression. …”
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9488
Construction and application of a TCN-LSTM-SVM-based time series prediction model for water inflow in coal seam roofs
Published 2025-06-01“…BackgroundThe accurate prediction of mine water inflow plays a significant role in the prevention and control of water hazards and the safe and efficient production in coal mines. MethodsTo construct a prediction model of water inflow in mines under threat of water hazards from extremely thick sandstones aquifer in West China, this study investigated a typical mine (also referred to as the studied mine) severely affected by such water hazards in the Binchang mining area of Shaanxi Province. …”
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9489
Abstract 054: Transradial Thrombectomy Using "Sheathless PV" Guide Catheter in Armenia: Three‐Year Institutional Experience in 103 Cases
Published 2023-11-01“…It offers numerous advantages and stimulated development of long flexible large lumen guiding catheters as well as adoption of existing cost‐efficient alternatives used in cardiac and peripheral interventions (2,3). …”
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9490
Gestational Diabetes Management and Outcomes in South Jordan: Metformin Alone vs. Metformin-Insulin Therapy, A Retrospective Cohort Study
Published 2024-11-01“…The primary goal was to develop an efficient management system that reduces hospital admissions and improves outpatient care for pregnant women with diabetes. …”
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9491
MIF tautomerase inhibitor TE-11 prevents inflammatory macrophage activation and glycolytic reprogramming while reducing leukocyte migration and improving Crohn’s disease-like colit...
Published 2025-04-01“…Here, we tested TE-11, a potent MIF tautomerase inhibitor (IC50 = 5.63 μmol/dm3) in experimental Crohn’s disease in male mice, in leukocyte recruitment and in inflammatory M1 macrophage activation.Methods2,4,6-trinitrobenzenesulfonic acid-(TNBS)-induced colitis was utilized as a CD-model in male mice. …”
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9492
7aaRGD - a novel SPP1/integrin signaling-blocking peptide reverses immunosuppression and improves anti-PD-1 immunotherapy outcomes in experimental gliomas
Published 2025-04-01“…We hypothesized that a combination strategy aiming to block the reprogramming of GAMs using a synthetic 7aaRGD peptide that targets SPP1/integrin signaling might overcome resistance to ICIs and reinvigorate anti-tumor immunity. Methods Matrigel invasion assay was used to test the efficacy of 7aaRGD in glioma-microglia co-cultures. …”
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9493
Combined exercise training and dietary interventions versus independent effect of exercise on ectopic fat in individuals with overweight and obesity: a systematic review, meta‐anal...
Published 2025-12-01“…Additional investigation is required to delve into the processes behind these findings and to pinpoint treatments that efficiently focus on reducing ectopic fat.…”
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9494
GULP1 as a novel diagnostic and predictive biomarker in hepatocellular carcinoma
Published 2025-07-01“…In this study, we aimed to identify the predictive gene signatures for HCC recurrence and evaluate the efficiency of GULP PTB domain-containing engulfment adaptor 1 (GULP1) as a predictive and diagnostic marker and therapeutic target for HCC. …”
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9495
Investigating the relationship between the monetary policy shock through the exchange rate channel on the management quality index in the banking system: by examining the productiv...
Published 2025-03-01“…The current research is applied in terms of its purpose and analytical-descriptive in terms of its method. This study utilizes 96 variables of seasonal time series data that affect the management quality index within the bank productivity framework, one of the critical indicators for assessing the health of the banking system. …”
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9496
Novel Pt@PCN-Cu-induced cuproptosis amplifies αPD-L1 immunotherapy in pancreatic ductal adenocarcinoma through mitochondrial HK2-mediated PD-L1 upregulation
Published 2025-05-01“…Methods Pt@PCN-Cu was synthesized via a one-pot method, and its therapeutic potential was assessed in combination with αPD-L1 for the treatment of PDAC. …”
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9497
Use of explainable AI on slit-lamp images of anterior surface of eyes to diagnose allergic conjunctival diseases
Published 2025-01-01“…Thus, the purpose of this study was to develop an explainable AI model that can not only diagnose ACDs but also present the basis for the diagnosis. Methods: A dataset of 4942 slit-lamp images from 10 ophthalmological institutions across Japan were used as the image database. …”
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9498
Demographic Linkages between Rural and Urban Areas and Its Impact on Creating Social Capital (Case study: Damavand, Firouzkoh, Shemiranat)
Published 2019-03-01“…The samples of this study were selected radomly from 7 districts and 26 villages located in Damavand, Firuzkoh, and Shemiranat. The main methods to analyze the collected data were network analysis and cross- impact analysis; the results of these methods led to the determination of impacts demographic linkages on creation of social capital. …”
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9499
What sizes of droplets contribute to long-range airborne transmission?
Published 2024-12-01“…The size range of respiratory droplets contributing to long-range airborne transmission of infections determines the targeted intervention methods. However, the exact size range remains unknown, and the influencing parameters are also undetermined. …”
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9500
Subsurface cavity detection in a karst environment using electrical resistivity (er): a case study from yongweol-ri, South Korea
Published 2012-10-01“…A numerical modelling study preceded the field survey to determine whether the electrical resistivity method could identify such features. …”
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