Unveiling Functional Impairment in Fabry Disease: The Role of Peripheral vs. Cardiac Mechanisms by Geza Halasz, Chiara Lanzillo, Raffaella Mistrulli, Emanuele Canali, Elisa Fedele, Paolo Ciacci, Federica Onorato, Guido Giacalone, Giovanni Nardecchia, Domenico Gabrielli, Federica Re

“…<b>Methods:</b> Thirty-one patients with genetically confirmed AFD were retrospectively enrolled from two tertiary centers. …”
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Access and coverage of malaria services in Haiti in the context of elimination: a scoping review of the literature by Kenny Moise, Aude Melody Achille, Roubens Duvilaire, Jimmy Fedna, Roody Thermidor, Bertiny Bourdeau, Jessica Maureen Nestor, Gérald Lerebours, Jean Hugues Henrys, Christian Raccurt

“…The Ministry of Health established a strategic plan covering the 2021–2030 period, providing a framework for operational planning to increase efficiency, strengthen the health system, and ensure the sustainability of interventions. …”
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Metabolome and transcriptome analysis reveal the pigments biosynthesis pathways in different color fruit peels of Clausena lansium L. Skeels by Zhichang Zhao, Mark Owusu Adjei, Ruixiong Luo, Huaping Yu, Yali Pang, Jian Wang, Yu Zhang, Jun Ma, Aiping Gao

“…The significant increase of F3H expression in purple peels suggested a higher efficiency of catalyzing the conversion of naringenin into dihydroflavonols in the PP, leading to the higher content of total anthocyanin. …”
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Predicting the Permeability of Pervious Concrete Based on the Beetle Antennae Search Algorithm and Random Forest Model by Jiandong Huang, Tianhong Duan, Yi Zhang, Jiandong Liu, Jia Zhang, Yawei Lei

“…The results showed that the hyperparameters of RF can be tuned by the BAS efficiently; the BAS can combine the conventional RF algorithm to construct the evolved model to predict the permeability of pervious concrete; the cement/aggregate ratio was the most significant variable to determine the permeability, followed by the coarse aggregate proportions.…”
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Machine Learning for Non-Destructive Prediction of Sunflower Leaf Area by Joao Everthon da Silva Ribeiro, Antonio Gideilson Correia da Silva, Pablo Henrique de Almeida Oliveira, Josiana Micarla da Silva Oliveira, Alessandra Nunes da Silva, John Victor Lucas Lima, Ivan Euzebio da Silva, Ester Dos Santos Coelho, Isaque de Oliveira Leite, Elania Freire da Silva, Toshik Iarley da Silva, Lindomar Maria da Silveira, Aurelio Paes Barros Junior

“…This ANN model was subsequently implemented in the web interface, offering an efficient, non-destructive tool for estimating sunflower leaf area based on linear dimensions.…”
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7aaRGD - a novel SPP1/integrin signaling-blocking peptide reverses immunosuppression and improves anti-PD-1 immunotherapy outcomes in experimental gliomas by Aleksandra Ellert-Miklaszewska, Paulina Pilanc, Katarzyna Poleszak, Adria-Jaume Roura, Salwador Cyranowski, Mitrajit Ghosh, Szymon Baluszek, Maria Pasierbinska, Bartłomiej Gielniewski, Julian Swatler, Yuliana Hovorova, Kamil Wojnicki, Bozena Kaminska

“…The effects of treatments on the tumor immune landscape were dissected using multiparameter flow cytometry, immunocytochemistry, cytokine profiling and RNA-seq analysis of sorted GAMs followed by CITE-seq based data deconvolution. Results 7aaRGD efficiently blocked microglia-dependent invasion of human and mouse glioma cells in vitro. …”
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Combined exercise training and dietary interventions versus independent effect of exercise on ectopic fat in individuals with overweight and obesity: a systematic review, meta‐anal... by Fatemeh Kazeminasab, Motahareh Mohebinejad, Mohammad Hossein Mahboobi, Maedeh Nojoumi, Saba Belyani, Reza Bagheri, Fred Dutheil

“…Additional investigation is required to delve into the processes behind these findings and to pinpoint treatments that efficiently focus on reducing ectopic fat.…”
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Administrative Barriers to the Development of Small and Medium-Sized Businesses in the Republic of Mordovia: Materials of Practical Research by M. V. Bikeeva, V. A. Inshakov, I. M. Fadeeva

“…In this regard, there is a need for a statistical assessment of the conditions for doing business at the regional level for the subsequent determination of directions for increasing the efficiency and effectiveness of the activities of state (municipal) authorities and identifying reserves for improving the business environment.Materials and methods. …”
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Short Term Analysis of New Single-Piece Aspheric Diffractive Trifocal Intraocular Lens Implantation by K. B. Pershin, N. F. Pashinova, M. M. Konovalova, A. Yu. Tsygankov, M. E. Konovalov, N. E. Temirov

“…Implantation of the examined IOL is associated with a high efficiency for near, intermediate distance and far vision correction. …”
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Value Propositions for Digital Shared Medication Plans to Boost Patient–Health Care Professional Partnerships: Co-Design Study by Benjamin Bugnon, Francesca Bosisio, Alain Kaufmann, Pascal Bonnabry, Antoine Geissbuhler, Christian von Plessen

“…MethodsWe used an experience-based co-design approach in the French-speaking region of Switzerland. …”
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Evaluating the effectiveness of handheld ultrasound in primary blast lung injury: a comprehensive study by Shifeng Shao, Zhengbin Wu, Jun Liu, Zhikang Liao, Yuan Yao, Liang Zhang, Yaoli Wang, Hui Zhao

“…The scores accurately predicted injury severity at various time points within 24 h post-injury, and the 0.5 h lung ultrasound score predicted 24 h mortality with 95.8% efficiency. PBLI exhibits hidden severity, necessitating improved early diagnostics. …”
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SerpinA5 Inhibits Malignant Biological Behavior of Esophageal Squamous Cell Carcinoma by Regulating Fn/Integrin-β1 Signaling Pathway by Yu WEI, Zhouhua ZHANG, Zhifang LI, Li ZHANG

“…Coimmunoprecipitation (Co-IP) was employed to determine the interaction between SerpinA5 and Fn. …”
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Clinical Efficacy of a Position-Responding Mandibular Advancement Device in Patients With Obstructive Sleep Apnea by Sung-Woon On, Dong-Kyu Kim, Min Hyuk Lee, Ji Hae Lee, Kyung Chul Lee, Soo-Hwan Byun, Seok Jin Hong

“…Methods. Fourteen patients diagnosed with OSA participated in this study. …”
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Comparative study of the efficacy and safety of Chondroguard® during its combined (intra-articular and intramuscular) and intramuscular injection in patients with knee osteoarthrit... by L. I. Alekseeva, E. P. Sharapova, N. G. Kashevarova, E. A. Taskina, A. M. Lila, A. N. Bogdanov, S. A. Bozhkova, A. A. Bagretsova, S. M. Noskov, E. A. Grunina

“…All the patients were prescribed nonsteroidal anti-inflammatory drugs (NSAIDs), such as meloxicam 15 mg. To determine the efficiency of treatment, the investigators estimated the following parameters: pain intensity on a visual analogue scale (VAS), the total WOMAC index and its components (pain, stiffness, and functional insufficiency), sensory and affective-emotional pain characteristics (for the target joint) according to McGill Pain Questionnaire (MPQ) scores. …”
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Comparative assessment of primary and paraneoplastic gout in lung cancer by O. V. Syniachenko, Yu. V. Dumanskyi, Ye. D. Yehudina, O. Ye. Chernyshova, P. A. Stepko, D. M. Fedorov

“…The data presented in the study require further comparative analysis of the other signs of PNPS, comparison of tumor and idiopathic variants of the musculoskeletal system lesion, cutaneous vasculitis and autoimmune systemic syndromes, which might assist in developing of the additional prognostic criteria for the tumor process clinical course, increasing the efficiency of therapy and its control quality.…”
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Fracture identification and 3D reconstruction of coal-rock combinations based on VRA-UNet network by Dengke WANG, Longhang WANG, Yaguang QIN, Le WEI, Tanggen CAO, Wenrui LI, Lu LI, Xu CHEN, Yuling XIA

“…In the 3D reconstruction of coal-rock combinations fractures, in response to the problem that traditional threshold segmentation methods cannot accurately determine the threshold size between coal and rock, resulting in poor fracture segmentation performance, a new VRA-UNet coal-rock combinations fracture identification model based on deep learning theory is proposed, providing an optimized solution for accurate identification of coal-rock combinations fractures. …”
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Ecological adaptability of rice cultivars with different types under the low temperature and weak sunshine condition by LI Min, LUO Deqiang, JIANG Xuehai, ZHOU Weijia, GI Guangmei, WANG Xuehong, LI Shuxing

“…In comparison with the ecology-adaptive cultivars, the ecology-sensitive cultivars achieved 18.8%,10.8%,14.5% lower nitrogen accumulation amount at the mid-tillering (critical stage of productive tillering), heading, maturity stage, respectively, resulting in 17.9% lower nitrogen recovery efficiency (RE). Furthermore, a higher nitrogen accumulation amount in stem-leaves at the heading stage and a lower nitrogen accumulation amount in stem-leaves at the maturity stage were found in the ecology-sensitive cultivars, relative to the ecology-adaptive cultivars, and the nitrogen translocation amount from stems and leaves to panicle achieved 3.41 kg/667m², which was 24.6% lower than that in the ecology-adaptive cultivars, the nitrogen translocation ratio from stems and leaves to panicle achieved 38.55%, which was 19.4% lower than that in the ecology-adaptive cultivars. …”
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Is the Hip Keeping the Ankle Out of Work after Total Ankle Arthroplasty? by Frank DiLiberto PT, PhD, Maxine Olson MS, Finola Summerville, Stacey Meardon PhD, PT, Anand Vora MD

“…Methods: Ten people after TAA (69.6±8.6 years, 5 female, 45.4±9.2 months post TAA) and five healthy control participants (66.8±8.3 years, 2 female) have completed this ongoing case-control study. …”
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Modelos matemáticos para a secagem intermitente de arroz em casca Mathematical models for intermittent drying of rice by Volnei L. Meneghetti, Elvio Aosani, Jeferson C. da Rocha, Maurício de Oliveira, Moacir C. Elias, Ricardo S. Pohndorf

“…<br>This study aimed to adjust mathematical models to experimental values in function of the water content and study the effects of intermittent relations in drying of paddy grains in the efficiency of operation. Paddy grains produced in the southern region of Rio Grande do Sul were used. …”
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Reproductive impacts and disease burden of metritis and placental retention in dairy cows: A longitudinal monitoring study in Southern Vietnam (2022–2024) by Thuong Thi Nguyen, Lien Thi Bich Nguyen, Khang Nguyen Duong, Thuan Khanh Nguyen

“…Conclusion: Metritis and placental retention remain prevalent challenges in Vietnamese dairy herds, adversely impacting reproductive efficiency and calf health despite high treatment efficacy. …”
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