Decomposing door-to-needle time: insights into workflow delays and quality improvement in acute stroke care by Lianyan Wei, Hongfei Li, Zhuangzhuang Jiang, Dongjuan Xu, Xiaolan Wu

“…This study aimed to deconstruct DTN time into distinct workflow intervals to identify key determinants of delay and inform targeted quality improvement.MethodsThis retrospective study included 322 consecutive AIS patients treated with intravenous rtPA at Dongyang People’s Hospital between May 2023 and April 2025. …”
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Characterization of physical performance and change of direction deficit across age groups in young female volleyball players by João P Oliveira, Daniel A Marinho, Pedro Jacinto, Tatiana Sampaio, Jorge E. Morais

“…The change of direction (COD) deficit—a metric that isolates directional efficiency by comparing agility to linear speed—may provide a more nuanced understanding of an athlete’s movement capabilities. …”
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Compositional factors driving antibacterial efficacy in healthcare wet wipe products by Carolina Angulo-Pineda, Jian Ren Lu, Sarah Cartmell, Andrew J. McBain

“…In contrast, HPE, DPA, and ADM products demonstrated high efficiency, achieving >5 Log bacterial reduction within 60 s for all tested strains. …”
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Climate-responsive vector control strategies for Aedes albopictus by Jesús Bellver-Arnau, Laura Blanco-Sierra, Santi Escartin, Simone Mariani, Frederic Bartumeus

“…Even marginal improvements in vector control efficacy can be crucial in mitigating these risks. Methods In this study, we employed a metapopulation model to simulate Ae. albopictus population dynamics and dispersal, optimizing the timing and spatial allocation of larvicidal treatments. …”
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Erosion of porphyry copper deposits estimated by quantitative elemental content analysis on the example of Aktogay and Sungun ore fields by T. P. Morozova, V. V. Dyakonov

“…Porphyry copper deposits are attracting increased attention, which determines the relevance of studying their geochemical patterns to ensure a greater efficiency of geological fore casting. …”
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Emergy perspective on the environmental and economic viability of a biomass-driven polygeneration system by Parviz Heydari Nasab, Ata Chitsaz, Hiva Rashidzadeh, Alireza Rostamzadeh Khosroshahi

“…Innovative methods have been increasingly adopted to evaluate industrial processes’ sustainability, environmental impact, and economic feasibility. …”
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So long a toilet! Deviations from a conventional design, level of latrine construction and use by rural households in Nyanga district, Zimbabwe by S. Simbi, A. Kanda

“…Methods A semi-structured questionnaire was administered to 191 rural households who own BVIP latrines or their upgradable designs in a cross-sectional study in 2022. …”
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Optimizing pathophysiology instruction in dental school: examination paper analysis and strategic reflections by Zheng Wang, Xing-Long Zheng, Xi He, Jin-Jun Liu

“…This article analyzes the final pathophysiology examination paper for the 2021 grade dental medicine students at Xi’an Jiaotong University to understand the students’ knowledge mastery, assess teaching effectiveness, and ultimately improve teaching quality. Methods The theoretical examination results of 93 dental medicine students from the 2021 grade were analyzed and graded using the Optical Mark Recognition digital grading system to ensure accuracy and efficiency in processing multiple-choice responses. …”
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TBESO-BP: an improved regression model for predicting subclinical mastitis by Kexin Han, Yongqiang Dai, Huan Liu, Junjie Hu, Leilei Liu, Zhihui Wang, Liping Wei

“…The TBESO algorithm notably enhances the efficacy of the BP neural network in regression prediction, ensuring elevated computational efficiency and practicality post-improvement.…”
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IMPAIRED REGULATORY MECHANISMS OF THE mTOR SIGNALING PATHWAY IN OSTEOARTHROSIS by Elena Vasilyevna Chetina, E A Bratygina, E M Zaitseva, E P Sharapova, A L Alekseyeva, N V Demin, S A Makarov

“…Objective: to study the pattern of impaired regulatory mechanisms of the mammalian target of rapamycin (TOR) signaling pathway, by monitoring gene expression in the blood of patients with osteoarthrosis (OA) at different stages of the disease. Subjects and methods. The study covered 33 outpatients with OA, 14 patients with this condition prior to knee joint endoprosthesis, and 27 healthy individuals (controls) (mean age 58.0+7.4, 56.5+8.9, and 55.0+8.3 years, respectively). …”
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Research on artificial intelligence-driven container relocation problem for green ports by Sisi Zheng, Jin Sha, Yinying Kong, Yougan Wang

“…IntroductionContainer relocation in port yards represents a canonical NP-hard problem, characterized by high-dimensional nonlinear constraints and stringent real-time decision-making requirements.MethodsThis study proposes a unified framework integrating an Intelligent Decision-Driven Model (IDDM), an Adaptive Data Generator (ADG), and an Optimization–Learning Closed-Loop Framework (OLCF).ResultsThe IDDM leverages heuristic search and machine learning within a multi-stage decision mechanism to mitigate the curse of dimensionality; in two-dimensional scenarios involving 50–100 containers, the model achieves an average response time of 9.83 ± 0.12 µs and reduces relocation operations by 61.68%. …”
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Metronome-guided Rhythmic Auditory Stimulation with Visual Feedback for Fall Prevention in Elderly: A Randomised Controlled Trial by Abha Khisty, Zafar Azeem, Tushar Palekar

“…Materials and Methods: This randomised controlled trial was conducted at the Department of Physiotherapy, Dr. …”
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A Personalized Approach to the Treatment of Primary Open-Angle Glaucoma by A. L. Onishchenko, N. V. Maltseva, A. Sh. Smirnova, O. M. Kazantseva, S. I. Makogon

“…Aim — to study of gene polymorphisms affecting the effectiveness of timolol treatment of primary open-angle glaucoma.Patients and Methods. The study included 39 Russian patients (29 women and 10 men) aged 53 to 89 years old with a diagnosis of primary open-angle glaucoma (POAG). …”
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ESOPHAGEAL PATHOLOGY IN SCLERODERMA SYSTEMATICA: CLINICAL AND ENDOSCOPIC FINDINGS by A E Karateev, M M Movsisyan, L P Ananyeva, S G Radenska-Lopovok

“…Objective: to evaluate the incidence, clinical symptoms, and endoscopic picture of esophageal pathology in patients with SDS, as well as the efficiency of therapy with proton pump inhibitors (PPIs). …”
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Machine Learning-Based Predictive Maintenance for Photovoltaic Systems by Ali Al-Humairi, Enmar Khalis, Zuhair A. Al-Hemyari, Peter Jung

“…This paper introduces an AI-based robotic cleaning system that can independently forecast and schedule cleaning sessions from real-time sensor and environmental data. Methods: The system integrates sources of data like embedded sensors, weather stations, and DustIQ data to create an integrated dataset for predictive modeling. …”
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Evaluating Key Biomotor Abilities: A Comparison between National and International Elite Tennis Players by Pratham Singh, Dharmander Kumar, Mohit Morya, Rishabh Singh, Md. Hamidur Rahman

“…Biomotor ability is essential for elite tennis players, as it significantly contributes to increased efficiency, responsiveness and overall performance on the court. …”
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Menadione Sodium Bisulfite Loaded Rhamnolipid Based Solid Lipid Nanoparticle as Skin Lightener Formulation: A Green Production Beside In Vitro/In Vivo Safety Index Evaluation by Fatemeh Asadpour Panbehchouleh, Hossein Amani, Majid Saeedi

“…Purpose: In the current investigation, an ultrasonic approach was performed to produce menadione sodium bisulfite-loaded solid lipid nanoparticles (MSB-SLNs) with rhamnolipid as bio-surfactant, which aimed to increase the dermal delivery and anti-pigmentation effect. Methods: To achieve optimum delivery for MSB, the impact of the ratio of two surfactants (rhamnolipid: Tween) on nanoparticle attributes and the respective functions were evaluated. …”
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Optimal Pre-disaster and Post-disaster Scheduling of Mobile Energy Storage Considering the Influence of Transportation Network by XIE Peikun, LI Liang, SHI Yuanjie, SHENG Qing, LI Zhenkun

“…However， existing research primarily focuses on the post-disaster scheduling of MES， neglecting the critical impact of traffic conditions， thereby failing to maximize the emergency response capabilities of MES. [Methods] Therefore， this study proposes an MES scheduling strategy that integrates both pre- and post-disaster dynamic scheduling， accounting for the influence of transportation networks. …”
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Dispersion of optical constants of Si:PbGeO crystal in the terahertz range by V. R. Bilyk, K. A. Brekhov, M. B. Agranat, E. D. Mishina

“…To evaluate switching efficiency, both linear (refractive index and absorption coefficient) and non-linear optical characteristics (quadratic and cubic susceptibilities) are required. …”
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Production of aluminum alloys in electrolysis cells based on Hall-Héroult process: a review by ZHANG Cheng, XUE Ji-lai, LIU Xuan, LI Xiang, ZHU Jun, LIU Qiao-chu, QIAN Yi

“…Compared with the traditional alloy production methods, H-H-based processes have a great potential in improving product quality, simplifying production process, and reducing energy consumption. …”
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