MDNN-DTA: a multimodal deep neural network for drug-target affinity prediction by Xu Gao, Xu Gao, Mengfan Yan, Mengfan Yan, Chengwei Zhang, Chengwei Zhang, Gang Wu, Gang Wu, Jiandong Shang, Jiandong Shang, Congxiang Zhang, Congxiang Zhang, Kecheng Yang, Kecheng Yang

“…Determining drug-target affinity (DTA) is a pivotal step in drug discovery, where in silico methods can significantly improve efficiency and reduce costs. …”
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Lifetime history of hypertensive disorders of pregnancy is associated with shorter sleep duration and more sleep disturbance in midlife: results from the Project Viva women’s healt... by Kimia Heydari, Sheryl L. Rifas-Shiman, Suzanne M. Bertisch, Elizabeth B. Klerman, Jorge E. Chavarro, Emily Oken, Karen M. Switkowski

“…The relationship of HDP with sleep health in midlife, when sleep problems are common, remains unclear. Methods We studied women enrolled in Project Viva during early pregnancy (1999–2002) with sleep outcomes assessed in midlife (2017–2024). …”
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Novel AP39-Loaded Liposomes Sustain the Release of Hydrogen Sulphide, Enhance Blood-Brain Barrier Permeation, and Abrogate Oxidative Stress-Induced Mitochondrial Dysfunction in Bra... by Al Tahan MA, Marwah MK, Dhaliwal M, Diaz Sanchez L, Shokr H, Kaur M, Ahmad S, Badhan RK, Dias IH, Sanchez-Aranguren L

“…Entrapment efficiency was determined using HPLC, while cytotoxicity was assessed in human vein endothelial (HUVEC) and neuroblastoma (SHSY5Y) cells. …”
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Forced randomization: the what, why, and how by Kerstine Carter, Olga Kuznetsova, Volodymyr Anisimov, Johannes Krisam, Colin Scherer, Yevgen Ryeznik, Oleksandr Sverdlov

“…A better understanding of statistical properties of FR is warranted. Methods We described four different IRT configurations with or without FR and illustrated them using a simple example. …”
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First and Second‐Trimester Screening, for Down's Syndrome: An Umbrella Review on Meta‐Analyses by Zahra Goudarzi, Mojtaba Jafari, Zahra Shirvani, Mahmood Salesi, Khosro Keshavarz, Bahya Namvar Jahromi

“…Methods The data sources, including Scopus, Cochrane Library, and PubMed, were reviewed. …”
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Bioprocess exploitation of microaerobic auto-induction using the example of rhamnolipid biosynthesis in Pseudomonas putida KT2440 by Jakob Grether, Holger Dittmann, Leon Willems, Tabea Schmiegelt, Elvio Henrique Benatto Perino, Philipp Hubel, Lars Lilge, Rudolf Hausmann

“…A critical threshold of about 20% oxygen saturation was determined. Conclusions Utilizing the inherent tolerance of P. putida to microaerobic conditions in combination with the application of homologous, low-oxygen inducible promoters is a novel and efficient strategy to control bioprocesses. …”
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A Comparison of Water Flooding and CO₂-EOR Strategies for the Optimization of Oil Recovery: A Case Study of a Highly Heterogeneous Sandstone Formation by Dung Bui, Son Nguyen, William Ampomah, Samuel Appiah Acheampong, Anthony Hama, Adewale Amosu, Abdul-Muaizz Koray, Emmanuel Appiah Kubi

“…Using production data from twelve production and three monitoring wells, a dynamic reservoir model was built and successfully history-matched with a 1% deviation from actual field data. Three main recovery methods were evaluated: water flooding, continuous CO₂ injection, and water-alternating-gas (WAG) injection. …”
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Predicting the uplift capacity of circular anchors in frictional-cohesive soils using Kolmogorov-Arnold networks by Tran Vu-Hoang, Tan Nguyen, Jim Shiau, Hung-Thinh Pham-Tran, Trung Nguyen-Thoi

“…Additionally, a closed-form solution for stability factors is derived through KAN, providing an efficient method for predicting bearing capacity. The optimized models exhibit high coefficient of determination (R²) values and low root mean square errors (RMSE) for training and testing datasets. …”
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Hybrid Vehicle Battery Health State Estimation Based on Intelligent Regenerative Braking Control by Chellappan Kavitha, Gupta Gautam, Ravi Sudeep, Chidambaram Kannan, Bragadeshwaran Ashok

“…In this study, a fuzzy logic estimation method is deployed to determine the tire road friction coefficient (TRFC) and various control strategies are adopted to establish regenerative cut-off points. …”
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BACTERIAL PATTERNS AND URINE CULTURE SENSITIVITY DESCRIPTION OF UROLOGY PATIENTS IN THE PAEDIATRIC POPULATION AT TERTIARY HOSPITAL by Veryne Ayu Permata, Johan Renaldo, Naritha Vermasari

“…Material & Methods: Medical record data and the microbiology laboratory database were studied retrospectively using a descriptive method. …”
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Effect of Dynamic Injection Velocity and Mixed Wettability on Two-Phase Flow Behavior in Porous Media: A Numerical Study by Wei Hui, Le Wang, Xurui Liu, Yueshe Wang

“…Initially, a dynamic injection velocity method and a computational domain model considering non-dominant/dominant wetting angles were proposed. …”
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SPECIALIZED MAPPING OF CRUSTAL FAULT ZONES. PART 1: BASIC THEORETICAL CONCEPTS AND PRINCIPLES by K. Zh. Seminsky

“…In view of the above, specialized mapping can be proposed as one of the most efficient methods of studying the fault structure of the Earth’s crust.Part 2 will describe cases of application of the proposed method to map fault zones and to identify fault types and stress fields varying in ages in the regions of faulting, including areas wherein rocks are poorly outcropped. …”
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Physical simulation of aerodynamic flow characteristics in a vertical diffuser with air supply through different pipe configurations by L. V. Plotnikov, A. F. Ryzhkov, V. A. Medvedev, M. D. Smirnykh, L. E. Osipov

“…Vertical cone diffusers are used in various technical applications: heat exchangers, gas cleaning units, boilers, industrial furnaces, dryers, ventilation devices, nozzle systems and others. For their efficient operation, it is necessary to ensure a uniform supply of the working medium to the device, which is determined by the characteristics of the flow in thediffuser. …”
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Linear Active Disturbance Rejection Control-Based Voltage Controller for Buck and Boost DC/DC Converters in DC Distribution Grids by Asimenia Korompili, Oemer Ekin, Marija Stevic, Veit Hagenmeyer, Antonello Monti

“…The formulation of the proposed L-ADRC model in the non-canonical form facilitates the employment of model-based estimation and feedback control methods, whose performance is determined through the design of several parameters. …”
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Hepatoprotective Activity of Pine cones Extract by D. K. Gulyaev, S. S. Zykova, V. D. Belonogova, D. O. Semakin, N. A. Buzmakova

“…The component composition of procyanidins in the extract was determined using ultra-efficient liquid chromatography with a mass selective detector. …”
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Social networks of educational purpose as a subject of protection in the preparation of specialists of information security by I. D. Rudinskiy, D. Ya. Okolot

“…Theoretical and empirical pedagogical methods were used to accomplish the objectives. This facilitated efficient systematization of the collected data for its successful study and identification of the most typical features of the social networks when applied in the educational process and extension of those with specific properties were identified. …”
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Successful domestication of Neonothopanus Hygrophanus (Mont.) De Kesel & Degreef and Lentinus Squarrosulus Mont., indigenous saprophytic edible mushrooms from Kibira National Park... by Vincent Nteziryayo, Anthony M. Mshandete, Donatha D. Tibuhwa

“…This study was undertaken to explore opportunities for domestication of saprophytic wild edible mushrooms from the Kibira National Park (KNP) in Burundi. Methods Samples of Lentinus squarrosulus Mont. and Neonothopanus hygrophanus (Mont.) …”
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Substantiation of the Line for the Primary Processing of Industrial Hemp lnto Hemp of the Same Type Undirected by E. V. Novikov, I. N. Altukhova, A. V. Bezbabchenko

“…The lines need to be efficient, low-cost and produce fiber of various qualities.Research purpose The research aimed to substantiate the design of a low-cost line for the primary processing of technical hemp harvested in autumn and spring as a tangled mass of broken stems, and work out the recommendations for processing raw materials.Materials and methods Autumn harvest hemp was processed in four ways: single, double, triple and quadruple pass through the flax line of primary processing, without changing the settings of the machines. …”
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Study on the Law of Mine Pressure Manifestation in Three-Soft Coal Seam Isolated Working Face by Hui Liu, Jiarui Sun, Tao Yang, Jie Zhang, Dong Liu, Haifei Lin, Jiayue Deng, Yiming Zhang

“…The stress levels are high, and the surrounding rock suffers severe damage, posing serious challenges to the safe and efficient extraction of the working face. Improving the service life of the retreating roadway in an isolated working face is a pressing technical issue that coal mining companies must address. …”
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Quality of Life and Functional Performance in Patients with Multiple Sclerosis by Marzena A. Humańska, Paweł Śnieg, Leokadia Rezmerska, Beata Haor, Mariola Głowacka, Mirosława Felsmann, Danuta Ponczek, Krystyna Kurowska, Agnieszka Pluta, Damian Czarnecki

“…The aim of the study was to evaluate functional capacity in patients with multiple sclerosis and its impact on quality of life. Materials and methods. The study was covered by 50 people. The tests were carried out using a diagnostic survey. …”
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