Accelerated Predictive Stability Testing: Accelerating Registration Phase and Application of Reduced Designs for Shelf-Life Determination of Parenteral Drug Product by Lara Pavčnik, Mateja Prunk, Tina Trdan Lušin, Robert Roškar

“…In contrast, ASAP provides an efficient approach to support drug product development and expedite regulatory procedures. …”
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Validity of ICD-10-CM codes for determination of diabetes type for persons with youth-onset type 1 and type 2 diabetes by Xia Li, Gloria C Chi, Sara Y Tartof, Jeff M Slezak, Corinna Koebnick, Jean M. Lawrence

“…We assessed the validity of International Classification of Disease, 10th Revision, Clinical Modification (ICD-10-CM) codes to discriminate between type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) among health plan members with youth-onset (diagnosis age <20 years) diabetes.Research design and methods . Diabetes case identification and abstraction of diabetes type was done as part of the SEARCH for Diabetes in Youth Study. …”
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Determination of the Activity Coefficients of Components in a Di-2-ethylhexylphosphoric Acid–n-Hexane Binary System Using Gas Chromatography by Vladimir Glebovich Povarov, Olga Vladimirovna Cheremisina, Daria Artemovna Alferova, Aleksandr Tomasovich Fedorov

“…This study was devoted to the determination of n-hexane’s concentrations in the vapor phase over D2EHPA solutions at 293.0 K using gas chromatography (GC) and isopiestic (IP) methods. …”
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Clinical prediction model by machine learning to determine the results of maternal dietary avoidance in food protein-induced allergic proctocolitis infants by Jing Li, Meng-yao Zhou, Yang Li, Xue Wu, Xin Li, Xiao-li Xie, Li-jing Xiong

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Salting-Out Assisted Liquid-Liquid Extraction of Cr (VI) from Water Samples before Its Determination by UV-Vis Spectrophotometry by Jote Dame, Feyisa Wedajo, Guyo Jilo Molole, Abera Gure

“…This paper proposes salting-out assisted liquid-liquid extraction for selective extraction of a Cr (VI)-1,5-diphenylcarbazide complex before its determination by UV-Vis spectrophotometry. Parameters affecting the complexation process and the extraction efficiency of the method were studied. …”
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The Determinants of Delays and Their Impact on Clinical End Points in Acute ST-Segment Elevation Myocardial Infarction: A Single-Center Experience by Kardelen Ohtaroglu Tokdil, Hasan Tokdil, Eser Durmaz, Bilgehan Karadag, Burcak Kilickiran Avci, Baris Ikitimur, Emre Ozmen, Alpin Mert Tekin, Betul Zehra Pirdal, Zeki Ongen

“…In addition, the effect of this delay on the patient’s prognosis has also been investigated. <i>Materials and Methods</i>: a total of 301 patients diagnosed with STEMI treated with primary percutaneous coronary intervention (pPCI) were included in the study. …”
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Determination of Trace Rare Earth Elements in Tungsten-Molybdenum Ore by Inductively Coupled Plasma-Mass Spectrometry with Microwave Digestion System by Junfei CAO, Ting WANG, Jian LI, Ying LI

“…During the pretreatment of tungsten and molybdenum ore samples, the alkali melting flux will introduce the salt matrix, and the tungsten and molybdenum elements in an acid dissolution condition are easy to hydrolyze into tungstic acid and molybdic acid and produce rare earth fluoride.OBJECTIVESTo establish an analytical method for accurate determination of the 16 rare earth elements including La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu, Y, and Sc, in tungsten-molybdenum ore by inductively coupled plasma-mass spectrometry (ICP-MS).METHODSTungsten-molybdenum ore samples were fast digested by microwave with four acid system (HNO3-HF-HClO4-HCl) in a high temperature and high-pressure environment. …”
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Tumor-infiltrating lymphocytes are the key determinants of pathological features associated with pathogenic BRCA variants in high-grade serous ovarian carcinoma by Dang H. Nguyen-Phan, Dang H. Nguyen-Phan, Dang H. Nguyen-Phan, Tin Dang, Anh N. Dang, Loc T. H. Huynh, Phuong T. B. Nguyen, Vu Q. Tran, Hanh T. T. Ngo, Thao T. P. Doan, Tu A. Thai, Chien-Chin Chen, Chien-Chin Chen, Chien-Chin Chen, Chien-Chin Chen

“…This approach is especially useful in resource-limited settings and can enhance diagnostic efficiency and clinical decision-making.…”
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Managerial Ownership, Company Size, and Profitability as Determinant Factors of Tax Avoidance in Food and Beverage Companies Listed on the IDX in 2020-2023 by Deni Rachmad Sulistiyanto, Heru Tjaraka

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Determination of Tungsten, Molybdenum and 5 Associated Elements in Tungsten-Molybdenum Ore by Inductively Coupled Plasma-Optical Emission Spectrometry with Direct Sintering by Zhou SONG, Yiping JI, Weihua WANG, Shaomin FANG, Jie YANG, Huoyan LUO, Yuqi ZHOU

“…It is insoluble in hydrochloric acid, nitric acid and aqua regia, and the alkali melting and mixed acid dissolution method was often selected for sample digestion. However, the matrix effect cause by the alkali melting method seriously affects the accuracy and detection limit of instrument testing; the acid dissolution method has low dissolution efficiency for tungsten, molybdenum and other insoluble elements, and requires a long time and a complex pretreatment process by using a variety of inorganic strong acids such as hydrofluoric acid and aqua regia, which can also cause damage to the analytical and testing instruments.OBJECTIVESTo develop a simple and efficient method for quantitative analysis of tungsten and molybdenum and its associated elements in tungsten-molybdenum ore.METHODSBased on alkaline melting and acid dissolution, a method was established by inductively coupled plasma-optical emission spectrometry (ICP-OES) with direct sintering and complex extraction of hydrochloric acid-phosphoric acid-citric acid. …”
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Simultaneous determination of 9 succinate dehydrogenase inhibitor compounds in vegetables by QuEChERS combined with gas chromatography-tandem mass spectrometry by LIU Jun, LUO Xianyong, CAO Qiaofeng, LI Jilong, ZHANG Bo, CEN Jianbin, LI Shan

“…The results of different levels of spiked experiments for 9 SDHIs showed a good recovery rate of 80.4%-98.2% and the relative standard deviations (RSDs) were 3.0%-7.9%. The method was efficient, fast, easy to operate, with low detection cost, high recovery rate, high sensitivity, and good reproducibility, which was suitable for batch determination of 9 SDHIs in daily vegetables.…”
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Microwave-assisted synthesis of antimony oxide nanoparticles for the determination of trace cadmium in mulberry leaf tea matrices by flame atomic absorption spectrophotometry by Merve Nur İnce, Hakan Serbest, Sezgin Bakirdere

“…Abstract In this study, a rapid, sensitive and accurate analytical method was optimized for the determination of trace levels of cadmium (Cd) by flame atomic absorption spectrophotometry (FAAS) after antimony oxide nanoparticles (AO-NPs)-based dispersive solid-phase extraction (DSPE). …”
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QuEChERS combined with ultra-high performance liquid chromatography-tandem mass spectrometry to determine acrylamide in Xinjiang Naan products by XU Man, SONG Shaolong, HU Jun, SHI Haiyun, LIU Jian

“…ObjectiveThis study aimed to establish a rapid and accurate analytical method for the determination of acrylamide in Xinjiang characteristic Naan products.MethodsThe methodology involved adding the internal standard 13C3-acrylamide isotope to the samples, followed by the sequential addition of 9 mL of water, 10 mL of acetonitrile, 6 mL of n-hexane, 6 g of anhydrous magnesium sulfate, and 1.5 g of sodium acetate salting agent. …”
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Determination of 17 types of phthalates in drinking water by solid-phase extraction coupled with multiple reaction monitoring of gas chromatography-mass spectrometry by SHI Mengxing, YANG Yan, DU Limin

“…The precision and accuracy of this method were assessed by determining the standard curves, detection limits, quantification limits, relative standard deviations (RSD) and average spiked recovery rates for the 17 types of PAEs. …”
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THERMO-TECHNICAL INVESTIGATIONS OF HEATING SKID HEARTH FURNACES OF PUSHER TYPE WITH THE AIM O F DETERMINATION AND IMPROVEMENT OF THEIR MAIN ENERGOTECHNOLOGICAL CHARACTERISTICS by D. V. Mendelev

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Electrosynthesis of coNi and FeNi LDHs and studying the effect of intercalated cobalt and iron on the electrocatalysis and determination of glucose in human salivary samples by Fatemeh Masoumi, Rahim Mohammad-Rezaei, Mahdi Golmohammadpour

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Novel gas-diffusion microextraction followed by gas chromatography coupled to tandem mass spectrometry methodology for the determination of fragrance allergens in cosmetic products by Ana Castiñeira-Landeira, Angel Gomez-Feas, Antonia M. Carro, Thierry Dagnac, Paulo J. Almeida, Maria Llompart

“…An efficient sample preparation method using gas-diffusion microextraction (GDME) followed by gas chromatography coupled to tandem mass spectrometry (GC-MS/MS) is proposed for the first time to determine fragrance allergens in both aqueous and alcohol-based cosmetic products. …”
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Characterization of slurries for slip casting via constant pressure filtration: determination of the most suitable slurry property for controlling the green-body density by Takamasa Mori, Chie Matsumoto, Kenta Kitamura, JunIchiro Tsubaki

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Development and validation of an open-source virtual reality environment for alcohol use disorder and determinants of cue-induced craving among Indian participants by Tamonud Modak, Sanjukta Ghosh, Abhijit R. Rozatkar

“…Virtual reality (VR) has allowed for efficient conducting of CE. Limited research exists on VR for AUD in Indian settings. …”
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Determination of 15 Rare Earth Elements in Phosphate Ores by Inductively Coupled Plasma-Mass Spectrometry with Atmospheric Pressure Closed Microwave Digestion by Nan ZHANG, Zhikang ZHENG, Jiasong WANG, Jiangping ZENG

“…Microwave digestion directly releases energy to the sample with high efficiency, and volatile elements are retained in the digestion solution to prevent volatilization from causing deviation of results and environmental pollution. …”
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