Design and Validation of a Multi-Epitope mRNA Vaccine Construct Against Human Monkeypox Virus (hMPXV) by Annotating Protein of Intracellular Mature Virus (IMV) Form of hMPXV by Mohammad Asrar Izhari, Siraj B. Alharthi, Raed A. Alharbi, Ahmad H. A. Almontasheri, Wael A. Alghamdi, Abdulmajeed Abdulghani A. Sindi, Ahmad Abdulmajed Salem, Ali Mahzari, Fahad Alghamdi, Ahmed R. A. Gosady

“…The constructed vaccine’s physiochemical and structural features (secondary and tertiary), with structural stability (confirmed by molecular docking followed by dynamic simulation with TLRs (TLR4 & TLR2) and MHCs), were determined. Additionally, cloning (using pET-28a(+) vector) was conducted to verify the vaccine’s expression potential and translation efficiency. …”
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Blackberry-Like Doxorubicin Loaded Hyaluronic Acid/Zinc Phthalocyanine Loaded Mesoporous Silica Nanocomposites for Long-Term Tumor Photodynamic and Chemotherapy Synergistic Therapy by Du S, Li L, Kou J, Zhu T, Song Z, Zhan Y, Wu D, Zhan W

“…In vitro and in vivo experiments determined tumor long-term PDT and CT synergistic therapy efficacy with DOX-HA/ZnPc-bMSN.Results: These nanocomposites achieved high ZnPc loading (DLC: 10.2% ± 1.6%) and efficient tumor accumulation, enabling prolonged systemic circulation (> 96 h) and sustained dual-drug release in vivo, realizing long-term photodynamic and CT synergistic therapy. …”
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Effect of seed pre-treatment with auxin and gibberellin on germination and yield of cowpea (Vigna unguiculata L.) by Fahimeh Darkatanian, Saeed Saeedipour

“…The main objective was to assess the physiological effect of Indole 3acetic acid (IAA) and gibberellic acid (GA3) on germination and seedling growth of cowpea.   Material and Methods This experiment was carried out at the Seed Testing Laboratory, Department of Seed Science & Technology, at the Shoushtar University in Iran, with an objective to determine the rate of seed germination and seedling growth which influenced by various concentrations of growth regulators in cowpea (Vigna sinensis L.). …”
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Army Air Defence in the Donbas in Spring 1943 (Case of 1257th Army Anti-Aircraft Air Defense Artillery Regiment) by Vyacheslav Terentev

“…Different means were used for improving the air defence efficiency, including organizational and staff changes. …”
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A Consensus Framework for Evaluating Dispute Resolution Alternatives in International Law Using an Interval-Valued Type-2 Fuzzy TOPSIS Approach by Ibrahim Yilmaz, Hatice Kubra Ecemis Yilmaz

“…—cost-efficiency, duration, impartiality, binding nature, and generalizability are considered essential in determining the best resolution method. …”
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Stability Analysis of Bread Wheat (Triticum aestivum L.) Genotypes by the Genotype × Genotype-Environment Biplot by Mohsen Esmaeilzadeh Moghadam, Manoochehr Dastfal, Seyed Mahmoud Tabib Ghaffary, Seyyed Bahram Anderzian4 Anderzian, Manoochehr Sayyahfar, Khaled Miri, Shirali Koohkan, Alireza Askari Kalestani

“…The weight of the obtained grains was measured by a digital scale and reported in hectares. Grain yield was determined using combined analyses of variance. The GGE biplot statistical method (genotype effect + genotype × environment interaction) was used to study the stability of genotypes in the studied environments. …”
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Strawberry Freshness Assessment by Hyperspectral Imaging by Georgiy V. Nesterov, Anastasia V. Guryleva, Milana O. Sharikova, Svetlana A. Sukhanova, Alexander S. Machikhin

“…Model evaluation was done using the coefficients of determination (R2), relative error (RE), and root mean squared error (RMSE). …”
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Association between the ratio of triglycerides to high-density lipoprotein cholesterol and nocturnal hypertension: a cross-sectional study in a Chinese population by Hezeng Dong, Zhaozheng Liu, Jinling Zhang, Ye Han, Jing Zhang, Yazhi Xi, Liping Chang, Yue Deng

“…Therefore, the present study aimed to determine the efficacy of the TG/HDL-C ratio in predicting the occurrence of nocturnal hypertension and reducing related adverse events.MethodOur rigorous cross-sectional study, which included 749 participants who underwent 24-hour ambulatory blood pressure monitoring at the Cardiology Center of Changchun University of Chinese Medicine Affiliated Hospital, allowed us to determine the association between the TG/HDL-C ratio and nocturnal hypertension. …”
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Comparing Raman and NanoSIMS for heavy water labeling of single cells by George A. Schaible, John B. Cliff, Jennifer A. Crandall, Jeremy J. Bougoure, Michael N. Mathuri, Alex L. Sessions, Joseph Atwood, Roland Hatzenpichler

“…Here, we study the relationship of the incorporation of a stable isotope (2H through incorporation of 2H2O) as determined by the two techniques and calculate a correlation coefficient to support the use of either technique when analyzing cells incubated with 2H2O. …”
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Experimentally Constrained Mechanistic and Data-Driven Models for Simulating NMDA Receptor Dynamics by Duy-Tan J. Pham, Jean-Marie C. Bouteiller

“…However, their dynamics are challenging to capture accurately due to their high complexity and non-linear behavior. <b>Methods</b>: This article presents the elaboration and calibration of experimentally constrained computational models of GluN1/GluN2A NMDA-R dynamics: (1) a nine-state kinetic model optimized to replicate experimental data and (2) a computationally efficient look-up table model capable of replicating the dynamics of the nine-state kinetic model with a highly reduced footprint. …”
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Coupling and Coordination Between Water Poverty and High-quality Economic Development in Yellow River Basin by Wang Shuhe, Wang Lijun

“…[Methods] Based on data from nine provinces in the Yellow River basin from 2010 to 2019, The entropy weight method was used with data from nine provinces (or regions) in the Yellow River basin from 2010 to 2019 to determine the water poverty index weight. …”
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Analysis of asymmetry factors in the development of the EU tourism industry by Maxim Polyakov, Vladimir Bilozubenko, Natalia Nebaba, Maxim Korneyev, Yelyzaveta Saihak

“…Based on the calculation of the asymmetry coefficient, a high level of heterogeneity of the tourism industry parameters in the EU countries for each of the indicators was demonstrated. …”
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Modeling the Sustainable Land-Use Allocation in the Great Isfahan Using Multi-Criteria Evaluation in GIS Environment by Zeynab karimzadehMotlagh, Ali Lotfi, Saeid Pourmanafi

“…Criterion weights were determined using AHP method and expert opinions. The map of the criteria and weights obtained were combined and the suitable areas of land-uses were designed using the WLC. 3-Results and Discussion The results of accuracy assessment of the land-use map with a Kappa coefficient of 88% indicate its acceptable precision. …”
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Effects of Subsetting by Parent Materials on Prediction of Soil Organic Matter Content in a Hilly Area Using Vis-NIR Spectroscopy. by Shengxiang Xu, Xuezheng Shi, Meiyan Wang, Yongcun Zhao

“…The results showed that the models based on the global calibrations can only make approximate predictions for SOM content (RMSE (root mean squared error) = 4.23-4.69 g kg-1; R2 (coefficient of determination) = 0.80-0.84; RPD (ratio of standard deviation to RMSE) = 2.19-2.44; RPIQ (ratio of performance to inter-quartile distance) = 2.88-3.08). …”
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Quantification of intra-amniotic inflammation in late preterm prelabour rupture of membranes by Marie Vajrychova, Jaroslav Stranik, Rudolf Kupcik, Michaela Sadibolova, Rudolf Kukla, Radka Bolehovska, Marian Kacerovsky

“…Levels of amniotic fluid proteins determined by MS were put into the correlation with IL-6 concentration determined by electrochemiluminescence immunoassay method (ECLIA). …”
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Improving prediction accuracy of hospital arrival vital signs using a multi-output machine learning model: a retrospective study of JSAS-registry data by Yasuyuki Kawai, Koji Yamamoto, Keisuke Tsuruta, Keita Miyazaki, Hideki Asai, Hidetada Fukushima

“…The Spearman’s correlation coefficients ranged from 0.54 to 0.86. The model outperformed other methods, especially for R² scores and residual standard deviations, demonstrating its superior ability to predict actual vital signs values. …”
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Mobile Apps Designed for Patients With Polycystic Ovary Syndrome: Content Analysis Using the Mobile App Rating Scale by Zahra Arabkermani, Saeed Barzegari, Atefeh Rouhani, Nilofar Nahavandi, Omer Gibreel, Ibrahim Arpaci

“…However, their rapid proliferation has brought about significant challenges regarding quality assessment and evidence-based determination. Therefore, establishing reliable quality assessment methods is essential to assist patients with PCOS in identifying effective and trustworthy mobile health tools. …”
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Caseinolytic proteases of Lactobacillus and Lactococcus strains isolated from fermented dairy products by Jasna Novak, Andreja Leboš Pavunc, Katarina Butorac, Martina Banić, Nina Čuljak, Helena Rak, Marina Blažević, Ana-Marija Iveljić, Jagoda Šušković, Blaženka Kos

“…Statistically, significant acidification capacity was determined for L. plantarum D13 in the optimal medium and by the proteolytic strain L. helveticus M92 in skimmed milk. …”
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LANGUAGE SPACE OF NEURAL NETWORKS: FEATURES AND DIFFERENCES FROM NATURAL LANGUAGE by Natalia B. Egorchenkova, Olga V. Korobova

“…Purpose – analysis of lexical and grammatical features of artificial intelligence language and comparison with human language. Materials and methods. To solve the tasks set in the research, we used various methods of analysis: observation, description, and the comparative method. …”
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Industrial Policy and Innovation Process in the Modern Russian Economy by Irek K. Nizamutdinov

“…Industrial policy is determined by the peculiarities of the innovation process implementation in the economic system. …”