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15701
Investigating the Response of Rainfed Chickpea (Cicer arietinum L.) to Different Nitrogen Fertilizer Levels in Cold Regions
Published 2025-05-01“…Materials and MethodsA randomized complete block design (RCBD) with three replications was employed during the 2022–2023 growing season to evaluate the N requirements of rainfed chickpea (cv. …”
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15702
THE FIRST RUSSIAN STRATEGIC STUDY OF PHARMACOTHERAPY FOR RHEUMATOID ARTHRITIS (REMARCA TRIAL): RESULTS OF 12-MONTH TREATMENT IN 130 PATIENTS
Published 2014-12-01“…To introduce treat-to-target recommendations is an important task of modern rheumatology; however, there is still a diversity of serious problems relating to a scientific rationale and a clinical one for this strategy and to the possibilities of its implementation in real clinical practice, in the rheumatology service of the Russian Federation in particular, by taking into account the specific features of funding for high-tech medical care.Objective: to determine the efficiency and safety of combined therapy with subcutaneous methotrexate (MT) and biological agents (BA) when using the treat-to-target strategy in patients with active early and extended-stage rheumatoid arthritis (RA) who have risk factors for a poor prognosis.Subjects and methods.The results of the REMARCA (Russian InvEstigation of MethotrexAte and biologicals in eaRly aCtive inflammatory Arthritis) trial of 130 patients followed up for 12 months or more were given. …”
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15703
THE FIRST RUSSIAN STRATEGIC STUDY OF PHARMACOTHERAPY FOR RHEUMATOID ARTHRITIS (REMARCA TRIAL): RESULTS OF 12-MONTH TREATMENT IN 130 PATIENTS
Published 2015-10-01“…To introduce treat-to-target recommendations is an important task of modern rheumatology; however, there is still a diversity of serious problems relating to a scientific rationale and a clinical one for this strategy and to the possibilities of its implementation in real clinical practice, in the rheumatology service of the Russian Federation in particular, by taking into account the specific features of funding for high-tech medical care. Objective: to determine the efficiency and safety of combined therapy with subcutaneous methotrexate (MT) and biological agents (BA) when using the treat-to-target strategy in patients with active early and extended-stage rheumatoid arthritis (RA) who have risk factors for a poor prognosis. …”
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15704
Group Authentication Key Agreement Protocol Based on Certificateless Cryptography in UAV Network
Published 2025-01-01“…Therefore, group key agreement protocols for UAV networks must provide a lighter computing process and stronger security guarantees.Methods This protocol adopts a certificateless key system. …”
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15705
Exploration and morphological characteristics evaluation of a tetraploid seedling from periclinal graft chimera Hongrou Huyou (Citrus unshiu + C. aurantium)
Published 2025-05-01“…Flow cytometry (FCM) was used to determine the ploidy level of the seedlings of Hongrou Huyou using a diploid species Hongrou Huyou as control. …”
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15706
Effects of Fagopyrum dibotrys rhizoma meal supplementation on productive performance, egg quality, egg nutritional value, and serum biochemical parameters of Shanma laying ducks
Published 2025-08-01“…This experiment was conducted to assess the impacts of FDRM supplementation in Shanma laying ducks diet by determining productive performance, egg quality, egg nutritional value, and serum biochemical parameters.MethodsWith similar laying performance (80.88 ± 5.17%) and body weight (1.24 ± 0.02 kg), 512 healthy 32-week-old Shanma laying ducks were randomly assigned to four groups consisting of eight replicates (16 ducks per replicate). …”
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15707
RNF31 induces paclitaxel resistance by sustaining ALYREF cytoplasmic–nuclear shuttling in human triple‐negative breast cancer
Published 2025-02-01“…Methods The subcellular proportion of ALYREF was detected in samples from patients with TNBC using immunohistochemistry to analyze the relationship between ALYREF distribution and paclitaxel response. …”
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15708
IL-19 as a promising theranostic target to reprogram the glioblastoma immunosuppressive microenvironment
Published 2025-03-01“…Targeting GBM-mediated immunosuppressive and invasive properties is a promising strategy to improve clinical outcomes. Methods We utilized clinical and genomic data from the Taiwan GBM cohort and The Cancer Genome Atlas (TCGA) to analyze RNA sequencing data from patient tumor samples, determining the association of interleukin-19 (Il-19) expression with survival and immunosuppressive activity. …”
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15709
STRAIN LOCALIZATION PECULIARITIES AND DISTRIBUTION OF ACOUSTIC EMISSION SOURCES IN ROCK SAMPLES TESTED BY UNIAXIAL COMPRESSION AND EXPOSED TO ELECTRIC PULSES
Published 2015-09-01“…The multichannel Amsy-5 Vallen System was used to record AE signals in the six-channel mode, which provided for determination of spatial locations of AE sources. Strain of the specimens was studied with application of original methods of strain computation based on analyses of optical images of deformed specimen surfaces in LaVISION Strain Master System.Acoustic emission experiment data were interpreted on the basis of analyses of the AE activity in time, i.e. the number of AE events per second, and analyses of signals’ energy and AE sources’ locations, i.e. defects.The experiment was conducted at ICMM with the use of the set of equipment with advanced diagnostic capabilities (as compared to earlier experiments described in [Zakupin et al., 2006a, 2006b; Bogomolov et al., 2004]). …”
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15710
School-level variation in children’s moderate to vigorous intensity physical activity before and after COVID-19: a multilevel model analysis
Published 2024-10-01“…Post lockdown, we collected accelerometer, individual and school data from 393 children in 23 of the same schools and 436 children in 27 of the same schools in 2021 (Wave 1) and 2022 (Wave 2), respectively. Methods Sources of variation (between-school, between-pupil and within-pupil) in child weekday moderate to vigorous physical activity at each wave were modelled using linear mixed-effects models with school-level wave random coefficients. …”
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15711
Unlocking data: Decision-maker perspectives on cross-sectoral data sharing and linkage as part of a whole-systems approach to public health policy and practice
Published 2024-11-01“…Aim We sought to work collaboratively with decision-makers relevant to healthy public policy and practice in Scotland to identify practical ways that cross-sectoral data sharing and linkage could be used to best effect to improve health and reduce health inequalities. Methods We facilitated three sequential stakeholder workshops with 20 participants from local and central government, public health teams, Health and Social Care Partnerships, the third sector, organisations which support data-intensive research and public representatives from across Scotland. …”
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15712
Mechanism of exogenous methyl jasmonate mediated AsA-GSH cycle in Summer Black grape against low temperature stress
Published 2025-08-01“…[Objective] The aim of this study was to explore the response mechanism of the exogenous Methyl jasmonate (MeJA) regulating the ascorbic acid-glutathione (AsA-GSH) cycle of Vitis vinifera Summer Black grape to low-temperature stress. [Methods] One-year-old Summer Black grape plants were used as materials, and different concentrations of MeJA treatment groups and low-temperature stress treatment groups were set up. (1) MeJA treatment: the selected 1-year-old Summer Black grape plants were randomly divided into 5 groups, with 10 plants in each group.0 (CK), 50, 100, 150, 200 μmol·L-1 MeJA solution were sprayed on the leaves, and the spraying amount was suitable for the uniform wetting of the leaf surface without water dripping. …”
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15713
Implementation of the mini-CEX in a paediatric emergency department
Published 2024-12-01“…Material and methods: Inclusion criteria: paediatrics residents in the first (MIR1) and second (MIR2) year of residency. …”
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15714
Rheumatoid arthritis in real clinical practice: initiation of therapy with biological agents. Results of the «Computer Terminals of Self-Assessment for Patients with Rheumatic Dise...
Published 2019-09-01“…Objective: to assess quality-of-life (QoL) dynamics in patients with rheumatoid arthritis (RA) when initiating therapy with biological agents (BAs) in real clinical practice.Patients and methods. The investigation enrolled patients with RA from the patient cohort participating in the TERMINAL-II multicenter Russian study, who newly initiated BA therapy. …”
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15715
Stability of developing oil companies of Russia
Published 2017-08-01“…In the article the questions of stability of developing Russian companies of an oil and gas complex are considered; methodological and methodical approaches to the analysis of stability of the oil companies as difficult, open spontaneous social and economic systems are stated; results of the stability assessment of their development on the basis of determining indexes of economic efficiency, ecological and social responsibility, and also innovative activity are presented.…”
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15716
Development Level Evaluation of Tax Governance Digitalization Using Quadripartitioned Single-Valued Neutrosophic Sets
Published 2025-07-01“…A key component of improving the accountability, efficiency, and openness of public financial institutions is the digital transformation of tax governance. …”
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15717
Addressing Shortcomings in Contingency Standards of Care
Published 2022-09-01“…Without a formal system to guide the process or transition from the usual method of allocation to the contingency period, contingency decisions about who gets a scarce resource may continue to operate on an implicit FCFS basis, even when approaching crisis levels of scarcity. …”
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15718
Development of a clinical decision support tool for Primary care Management of lower Urinary tract Symptoms in men: the PriMUS study
Published 2025-01-01“…Objectives 1 and 2: development of statistical models and diagnostic accuracy Methods Men presenting to their GP with LUTS were recruited prospectively from GP practices in Bristol, Newcastle upon Tyne and Wales. …”
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15719
The results of the analysis of the research-methodological functions of the test current control of knowledge for natural sciences in MGRI
Published 2019-11-01“…It has confirmed that the test system of the current control allowed carrying out effective diagnostics of higher education, making more systematic and effective carrying out of lessons, organization of the self-control over the digestion of some topics of the course and correction lecture material in order to increase the efficiency of the training. The consequence of methodically correct organization of systematic test control is the formation of holistic natural science world view by students, as well as the culture of educational process by students — concentration, responsibility, accuracy, ability to develop internal and external self-organization and self-control. …”
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15720
L’ESTHÉTIQUE LITTÉRAIRE ORALE, POUR UNE APPROCHE AFRICAINE D’UN ÉNONCE SENTENCIEUX GULMANCE
Published 2024-12-01“…L’objectif de cet article est de revisiter cette nouvelle approche et d’en déterminer son efficience quant à la lecture du discours oral africain. …”
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