Body composition of metabolically unhealthy normal-weight patients with aortic stenosis: a prospective cohort study by Shuangxiang Lin, Chenjia Liu, Xingfa Ding, Shuyue Wang, Jiaxing Wu, Xinhong Wang, Jianzhong Sun

“…Incremental discriminative improvement (IDI) and the C-index were used to determine the influence of hybrid parameters on the predictive efficiency of the model. …”
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Exploring Older Adults’ Perspectives and Acceptance of AI-Driven Health Technologies: Qualitative Study by Arkers Kwan Ching Wong, Jessica Hiu Toon Lee, Yue Zhao, Qi Lu, Shulan Yang, Vivian Chi Ching Hui

“…ObjectiveThe objectives of the study were (1) to investigate the attitudes and perceptions of older adults toward the use of AI-based health technologies; (2) to identify potential facilitators, barriers, and challenges influencing older adults’ preferences toward AI-based health technologies; and (3) to inform strategies that can promote and facilitate the use of AI-based health technologies among older adults. MethodsThis study adopted a qualitative descriptive design. …”
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GAME AS AN ELEMENT OF HYGIENE MOTIVATION OF PRE-SCHOOLERS by V.S. Melnyk, L.F. Horzov

“… The aim of our research was to evaluate the effectiveness of a game in teaching the pre-schoolers, and the degree of learning to preserve children`s dental health. Materials and methods. 56 pre-schoolers of the Kindergarten № 6, aged 4-6, took part in our research. …”
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THE REASONS THAT LEAD TO THE REDUCTION OF THE USE OF NON-REMOVABLE PROSTHESIS DESIGNS by M.J. Nidzelskyy, N.V. Tsvetkova, S.S. Yasnogorskaya

“…The aim of the study was to establish the causes leading to a decrease in frequency of use of orthopedic constructions. Materials and methods. For qualitative research prosthetics and the term of use removable dentures which are made in prosthetic dentistry clinic Poltava regional dental clinic we analyzed indicators restore chewing efficiency in 130 patients (38 men and 92 women), who addressed the orthopedic department for 2012-2014 and who for medical reasons have been removed fixed constructions. …”
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Innovative machine learning-based prediction of early airway hyperresponsiveness using baseline pulmonary function parameters by Hua Yang, Xingru Zhao, Zhuochang Chen, Lihong Yang, Guihua Zhao, Chenxiao Xu, Jinyi Xu

“…This study explores the potential of baseline pulmonary function parameters, particularly small airway indices, in predicting AHR and develops a machine learning-based model to improve screening efficiency and reduce unnecessary BPT referrals.MethodsThis retrospective study analyzed baseline pulmonary function data and BPT results from Henan Provincial People’s Hospital (May to September 2024). …”
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Postreperfusion Renal Allograft Biopsy Predicts Outcome of Single-Kidney Transplantation: A 10-Year Observational Study in China by Meifang Wang, Junhao Lv, Jie Zhao, Huiping Wang, Jianghua Chen, Jianyong Wu

“…We investigated the predictive value of postreperfusion biopsy on long-term allograft outcome after single-kidney transplantation. Methods: We retrospectively evaluated the significance of histologic findings, read by experienced renal pathologists, in 461 postreperfusion biopsy specimens collected from 2010 to 2017 after deceased donor renal transplant; and performed time-to-event analyses to determine the association between histology and hazard of death-censored graft failure. …”
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The evaluation of equipment remote operation and pyroprocessing verification in hot cell by NIU Yongsheng, SUN Lixin, WANG Baozhu, ZHANG Han, FU Haiying, DOU Qiang, ZHOU Wei, QIAN Yuan, LI Qingnuan

“…The hot cell is an important guarantee for the practical application of nuclear fuel reprocessing technology, therefore, a remote operation system suitable for reprocessing post-treatment process equipment is developed so that the pyroprocessing experiments of molten salt can be conducted in hot cell.PurposeThis study aims to evaluate equipment remote operation and pyroprocessing verification in hot cell.MethodsMain focus of this study was the fluoride volatility and vacuum distillation process of molten salt reactor fuel salts, and the remote operation evaluation of hot cell equipments and pyroprocessing verification experiments were carried out using multi-view coordination. …”
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Rootstock impacts on ‘USDA-ARS-Pawnee’ pecan growth, physiological traits, and soil microbial communities by Xinwang Wang, Keith Kubenka, Warren Chatwin, Angelyn Hilton, Braden Tondre, Tingying Xu, Lu Zhang

“…Twelve distinct rootstocks were evaluated to determine their influence on scion development. Measurements of photosynthesis rate (PSR) and water use efficiency (WUE) were collected to establish correlations with leaf size. …”
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Sequential therapy with rituximab and belimumab in patients with systemic lupus erythematosus by A. A. Mesnyankina, S. K. Solovyev, N. Yu. Nikishina, E. A. Aseeva, N. V. Demidova, E. L. Nasonov

“…Objective: to determine the efficiency of sequential (combined) therapy with rituximab (RTM) and belimumab (BLM) in patients with active systemic lupus erythematosus (SLE).Patients and methods. …”
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Patient Burden And Impact Of Moderate-to-Severe Atopic Dermatitis In the Spanish Healthcare System: The APOLO Cross-Sectional Study by Pablo De La Cueva Dobao, Laia Curto Barredo, Juan Francisco Silvestre Salvador, Esther Serra Baldrich, Pedro Herranz Pinto, Natalia Hernández Cano, Francisco Javier Ortiz De Frutos, Gastón Roustan Gullón, Rosa María Izu Belloso, Irene Arévalo Ortega, Alicia González Quesada, Manuel Galán Gutiérrez, Yolanda Gilaberte Calzada, Daniel Arumi Torredemer, Noelia Llevat Felius, Irene Hernández Martín, Francisco José Rebollo Laserna

“…Methods: The APOLO is a multicenter, descriptive, cross-sectional study conducted at 12 Spanish sites, in which participants completed a series of scales and questionnaires. …”
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Value of APACHE II, SOFA and CardShock scoring as predictive tools for cardiogenic shock: A single‐centre pilot study by Małgorzata Chlabicz, Wojciech Łaguna, Remigiusz Kazimierczyk, Ewelina Kazimierczyk, Paulina Łopatowska, Monika Gil, Bożena Sobkowicz, Karol A. Kamiński, Agnieszka Tycińska

“…Methods This was a single‐centre observational study conducted between May 2016 and December 2017. …”
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Viral characterization of the reassortants between canine influenza H3N2 and human pandemic (2009) H1N1 and avian H9N2 viruses in canine ex vivo tracheal explants by Tonia T. Kam, Christine H. T. Bui, Hin-Wo Yeung, Peter C. H. Wong, Alex W. H. Chin, John M. Nicholls, Malik Peiris, Kenrie P. Y. Hui, Leo L. M. Poon, Michael C. W. Chan

“…Given that the canine respiratory tract is susceptible to a wide range of influenza viruses, it is of interest whether H3N2-CIV are likely to reassort with human and avian IAVs to generate reassortants with increased zoonotic potential. Methods We conducted a co-infection study in canine tracheal explants. …”
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Profiling of driver mutations in lung adenocarcinoma patients identifies rare compound EGFR mutations sensitive to second-generation EGFR-TKIs by Jun Li, Cuiyun Zhang, Yuping Guan, Siyu Wang, Jiawen Zheng, Junnan Feng, Sile Han, Ruijuan Ma, Pengfei Ren, Shasha Li, Harry J. M. Groen, Klaas Kok, Anke van den Berg, Bing Wei, Jie Ma, Hongle Li, Yongjun Guo

“…Material and methods Targeted sequencing covering the hotspot regions of eight LUAD driver genes was performed across 853 treatment-naive LUAD patients admitted in Henan Cancer Hospital (HNCH cohort). …”
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The effect of tofacitinib on function and quality of life indicators in patients with rheumatoid arthritis resistant to synthetic and biological disease-modifying antirheumatic dru... by D. E. Karateev, D. E. Abdulganieva, A. R. Babaeva, A. A. Baranov, L. P. Evstigneeva, O. N. Ivanova, G. V. Lukina, E. L. Luchikhina, V. I. Mazurov, A. S. Misiyuk, O. V. Semagina, A. E. Sizikov, V. N. Sorotskaya

“…Tofacitinib (TOFA), a representative of a new class of targeted synthetic disease-modifying antirheumatic drugs (s-DMARD), is a promising drug for treating rheumatoid arthritis (RA) and other immune inflammatory diseases.Objective: to evaluate the efficiency and safety of therapy with TOFA in combination with methotrexate (MTX) and other s-DMARDs in real clinical practice in patients with active RA and previous ineffective therapy.Patients and methods. …”
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Identification and validation of reference genes for qPCR of Pseudomonas aeruginosa L10 under varying n-hexadecane concentrations by Huan Wang, Xiaobing Wang, Juntao Chen, Yumiao Zhang, Junhua Liu, Fangliang Xia, Jian Li, Tao Wu, Longxiang Liu

“…Abstract Pseudomonas aeruginosa can efficiently degrades petroleum hydrocarbons, but its degradation rate is affected by hydrocarbon pollutant concentrations, which must be neither too high nor too low. …”
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The diagnostic of PAX1 gene methylation in cervical lesions and its role in the triage of non-16/18 HR-HPV positive by Meng-Meng Chen, Meng-Meng Chen, Bing-Qiang Zhang, Bing-Qiang Zhang, Yan-Song Luan, Guo-Long Sun, Yun-Yuan Zhang, Xiao-Yan Zhou, Xi-Feng Zhang, Feng-Chun Gao, Jun-Mei Yu

“…ObjectiveThis study aims to systematically evaluate the application value of PAX1 gene methylation detection in cervical lesion screening and its potential advantages in the triage of non-16/18 high-risk human papillomavirus (HR-HPV) positive patients.Materials and methodsThis study enrolled 1,619 HPV-positive female patients who visited the Affiliated Hospital of Qingdao University from December 2023 to March 2025, with 989 patients ultimately meeting the inclusion criteria. …”
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Ending preventable maternal deaths in Malawi: the stakeholders consensus approach to identify maternal health needs priorities by Mtisunge Joshua Gondwe, Leonard Mndala, Chifundo Kondoni, Annie Kuyere Khumalo, Bertha Maseko, Laura Munthali, Catherine Bamuya, Rosemary Bilesi, Henry Phiri, Fannie Kachale, Malangizo Mbewe, Jennifer Riches, Maria Lisa Odland, Effie Chipeta, Elizabeth Chodzaza, David Lissauer, Alinane Linda Nyondo-Mipando

“…We undertook a national maternal health prioritisation exercise involving key stakeholders to enhance delivery of maternal care in Malawi. Methods During group discussions, the Nominal Group Technique was adapted to facilitate consensus on priorities after data and real-life experiences from service users were presented. …”
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Poisoning Epidemiology, Clinical Outcomes and Management Decisions for General Public Calls: A Cross-Sectional Analysis of a Nationwide Telehealth Toxicology Consultation Service D... by Abdullah A. Alharbi, Mohammed A. Muaddi, Meshary S. Binhotan, Ahmad Y. Alqassim, Ali K. Alsultan, Mohammed S. Arafat, Abdulrahman Aldhabib, Yasser A. Alaska, Eid B. Alwahbi, Meshari A. Almutairi, Mobarak Alharthi, M. Mahmud Khan, Mohammed Alabdulaali, Nawfal A. Aljerian

“…Methods We conducted a retrospective analysis of all public calls to the national TCS hotline between January 1 and December 31, 2023. …”
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Fistula Tract Laser Closure (FiLac) versus Standard Fistulectomy in the Treatment of Simple Perianal Fistula: A Prospective Interventional Study by Shreethi Sasidharan Pillai, D Balaji, Harshwanth Chandhar, G Tilak Ramu, K Shanmugapriya

“…Aim: To compare short-term (postoperative pain, bleeding, mean hospital stay) and intermediate-term (wound healing) outcomes between FiLaC and standard fistulectomy in the treatment of simple perianal fistulas. Materials and Methods: A prospective interventional study was conducted at SRM Medical College Hospital and Research Centre, Chengalpettu, Tamil Nadu, India, in the Department of General Surgery over a period of 18 months, involving 108 patients randomised into FiLaC (group A) and standard fistulectomy (group B). …”
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Dynamics of Kidney Function in Patients with Chronic Kidney Disease and Atrial Fibrillation Who Receive Dabigatran by N. A. Novikova, Z. K. Salpagarova, M. I. Chashkina, A. A. Bykova, Z. A. Alimova, А. S. Yadykina, D. F. Mesitskaya, N. A. Babakova, D. A. Andreev

“…Currently, there are scarce studies into the use of direct oral anticoagulants in patients with atrial fibrillation and chronic kidney disease (in case of Glomerular Filtration Rate (GFR) below 45 ml/min/1.73 m2).Aim. To determine the dynamics of GFR in patients with AF and CKD (in case of GFR below 45 ml/min/1.73 m2).Material and Methods. …”
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