The P Balasubramaniam Award-2024 Singapore Orthopaedic Association Annual Scientific Meeting Award: Novel artificial intelligence algorithm for soft tissue balancing and bone cuts... by Matthew Song Peng Ng, Ryan Wai Keong Loke, Melvin Kian Loong Tan, Yau Hong Ng, Zi Qiang Glen Liau

“…We aim to demonstrate the effectiveness of our novel algorithm in terms of accuracy and surgical duration. Methods We developed a novel AI computational algorithm to optimize rTKA implant positioning in three-dimensional space. …”
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EMCC dispatch priority for trauma patients in Norway: a retrospective cohort study by Inger Marie Waal Nilsbakken, Torben Wisborg, Stephen Sollid, Elisabeth Jeppesen

“…Methods This registry-based study included 3633 patients from the Norwegian Trauma Registry and Oslo EMCC during 2019–2020. …”
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Evaluation of Stress Hormone Levels, Preoperative Anxiety, and Information Needs before and after Hysteroscopy under Local Anesthesia in Relation to Transvaginal Procedures under G... by Karolina Chmaj-Wierzchowska, Katarzyna Wszołek, Adrian Nowak, Natalia Ignaszak-Kaus, Magdalena Muszyńska, Maciej Wilczak

“…To determine cortisol and prolactin levels using electrochemiluminescence, blood was collected from the patients on the day of admission to the hospital, i.e., the day of surgery, in the morning, while fasting. …”
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HIV treatment as prevention: systematic comparison of mathematical models of the potential impact of antiretroviral therapy on HIV incidence in South Africa. by Jeffrey W Eaton, Leigh F Johnson, Joshua A Salomon, Till Bärnighausen, Eran Bendavid, Anna Bershteyn, David E Bloom, Valentina Cambiano, Christophe Fraser, Jan A C Hontelez, Salal Humair, Daniel J Klein, Elisa F Long, Andrew N Phillips, Carel Pretorius, John Stover, Edward A Wenger, Brian G Williams, Timothy B Hallett

“…<h4>Methods and findings</h4>Twelve independent mathematical models evaluated a set of standardised ART intervention scenarios in South Africa and reported a common set of outputs. …”
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Econometric predictive model for assessing the functional state of students during the examination period: a cross-sectional exploratory pilot study by I. S. Knyazhev, L. V. Karaulova, O. V. Reztsov, A. P. Spitsin

“…Methods. The cohort observational study enrolled 74 students of Kirov State Medical University, aged 18–23 years, who gave consent to the survey. …”
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Nicotinamide mononucleotide biosynthesis and the F-actin cytoskeleton regulate spindle assembly and oocyte maturation quality in post-ovulatory aged porcine oocytes by Hyo-Jin Park, Seul-Gi Yang, Ji-Hyun Shin, Seung-Bin Yoon, Ji-Su Kim, Deog-Bon Koo

“…Here, we investigated the mechanisms by which the NAD+ salvage pathways function in poor oocyte maturation upon POA through the F-actin cytoskeleton. Methods Porcine oocytes were aged by extending in vitro maturation (IVM) for an additional 24 h to create a POA model. …”
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Enhanced Intranasal Delivery of Atorvastatin via Superparamagnetic Iron-Oxide-Loaded Nanocarriers: Cytotoxicity and Inflammation Evaluation and In Vivo, In Silico, and Network Phar... by Kristina Zarif Attalla, Doaa H. Hassan, Mahmoud H. Teaima, Carol Yousry, Mohamed A. El-Nabarawi, Mohamed A. Said, Sammar Fathy Elhabal

“…<b>Objective</b>: This study aims to develop an intranasal (IN) delivery system for glioblastoma multiforme (GBM) management using repurposed superparamagnetic iron-oxide (SPION) loaded with atorvastatin (ATO)-nanostructured lipid carrier (NLC). <b>Methods</b>: Emulsification and ultrasonication were used to formulate ATO-NLCs, and the best formula was loaded with SPION to make the final atorvastatin/superparamagnetic iron oxide-loaded nanostructured lipid carrier (ASN) formulation. …”
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Investigating the relationship between Pfkelch13 mutations and response to artemisinin-based treatment for uncomplicated falciparum malaria: a protocol for a systematic review and... by Prabin Dahal, Philippe Guerin, Farhad Shokraneh, James A Watson, Karen I Barnes, Aboubakar Soma, Stephanie van Wyk, Chistevy Vouvoungui, Dhol S Ayuen

“…ART-R has been causally linked to specific mutations in the Pfkelch13 gene.Methods and analysis The systematic review and associated meta-analysis aim to determine the correlation between Pfkelch13 (alleles present in the Kelch13 gene region of the P. falciparum parasite) genotypes and clinical and parasitological response to ACTs from a globally representative data set pooling individual patient data (IPD) from eligible published and unpublished studies. …”
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Factors influencing value-based care application among medical students and postgraduate in Thailand by Phoomjai Sornsenee, Kittisakdi Choomalee, Kamonlak Sanphet, Kanyarat Keereerak, Techin Wongwatthanawisit, Tanyamon Wongtabpabud, Panpim Tipphayawong, Panupong Khunjun, Suppanita Tularak, Kanisorn Sungkaro, Theepat Wongkittithaworn

“…Abstract Background The adoption of Value-Based Care (VBC) is essential for enhancing healthcare quality and efficiency, with implications for future healthcare delivery. …”
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RITUXIMAB THERAPY MONITORING IN PATIENTS WITH RHEUMATOID ARTHRITIS HROUGH PERIPHERAL BLOOD GENE EXPRESSION ANALYSIS by E. V. Chetina, A. V. Pivanova, K. Kh. Kuzikyants, A. Yu. Devyataikina, G. V. Lukina, E. Yu. Samarkina, A. P. Aleksankin, E. N. Aleksandrova

“…Objective: to determine the predictors of the efficiency of rituximab (RTM) therapy through analysis of blood gene expressions in patients with rheumatoid arthritis (RA). …”
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Adalimumab in Focus: Evaluating Effectiveness and Safety in Non-Infectious Uveitis at a Tertiary Referral Center in Türkiye by Berru Yargı Özkoçak, Çiğdem Altan, Burcu Kemer Atik, Berna Başarır

“…BCVA was monitored at baseline and subsequent months to determine the onset of functional efficiency of ADA treatment. …”
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Unplanned re-attendance to emergency department of patients with systemic inflammatory response syndrome: a situational analysis by Siwapon Srikeaw, Ketsarin Utriyaprasit, Wanlaya Thampanichawat, Siriorn Sindhu, Chukiat Viwatwongkasem, Thitipong Tankumpuan

“…Methods This study employed a cross-sectional and prospective cohort study design. …”
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Ethanol consumption during gestation promotes placental alterations in IGF-1 deficient mouse placentas [version 3; peer review: 1 approved, 2 approved with reservations, 1 not appr... by Mario Bermúdez De León, Diego Rodríguez-Mendoza, Carolina Zertuche-Mery, Inma Castilla-Cortázar, Oscar R Fajardo-Ramírez, Fabiola Castorena-Torres, Marcela Galindo-Rangel, Patricio Gómez-Álvarez, Irene Martín-Estal, Andrea Leal López

“…Methods Wild type (WT, Igf1 +/+) and heterozygous (HZ, Igf1 +/-) female mice were given 10% ethanol in water during 14 days as an acclimation period and throughout pregnancy. …”
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Evaluating spectral indices for water extraction: Limitations and contextual usage recommendations by Chuanwu Zhao, Haishuo Wei, Gudina Legese Feyisa, Thiaggo de Castro Tayer, Gelilan Ma, Hanyi Wu, Yaozhong Pan

“…Currently, various technologies have been applied to water information monitoring, with remote sensing-based spectral index methods being widely used due to their simplicity, low cost, and large-scale observation capabilities. …”
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AI-powered machine learning models for monitoring and optimization of biodrying process by Abhisit Bhatsada, Panida Payomthip, Tanik Itsarathorn, Ye Nyi Nyi Lwin, Eka Wahyanti, Sirintornthep Towprayoon, Suthum Patumsawad, Chart Chiemchaisri, Komsilp Wangyao

“…Among all models tested, deep learning methods demonstrated superior accuracy, with Long Short-Term Memory (LSTM) achieving the highest predictive performance (R² = 0.988 training, R² = 0.987 testing). …”
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An ecological study on the association between early childhood caries and intimate partner violence in 20 low- and middle-income countries: 2007-2017 [version 3; peer review: 2 app... by Morenike Oluwatoyin Folayan, Maha El Tantawi, Mary O. Obiyan, Ola B. Al-Batayneh, Arthur Kemoli, Robert J. Schroth, Balgis Gaffar

“…Methods: This was an ecological study using IPV (physical, sexual, emotional) data extracted from the Demographic Health Survey of 20 low- and middle-income countries and ECC data for 3-5-year-olds of the same countries for the period 2007-2017. …”
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A quadratic multinomial regression model was established for taste properties of main catechins and amino acid monomers in green tea by RAN Qiansong, LIU Zhongying, LIU Xi, HOU Yanshuang, BAO Fushu, PAN Ke

“…Y=-32.097 5+0.199 8X2+0.455 3X3+1.222 9X4+0.000 6X22+0.004 4X52-0.000 1X1X6-0.002 6X2X3-0.008 1X3X4-0.017 3X4X5+0.001 4X5X6; Y (fresh)=80.221 8-0.703 7X3+0.555 6X5-0.355 4X6+0.000 7X62-0.001 6X1X2-0.002 7X1X5+0.000 8X1X6+0.007 9X2X3-0.009 7X2X5+0.014 3X3X5-0.002 4X4X6-0.004 8X5X6; The correlation coefficients of the model were all > 0.890 1, and the determination coefficients were all >0.792 2. …”
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Ecological Momentary Assessment of Mental Health Problems Among University Students: Data Quality Evaluation Study by Ana Portillo-Van Diest, Philippe Mortier, Laura Ballester, Franco Amigo, Paula Carrasco, Raquel Falcó, Margalida Gili, Glenn Kiekens, Francisco H Machancoses, Jose A Piqueras, Marisa Rebagliato, Miquel Roca, Tíscar Rodríguez-Jiménez, Jordi Alonso, Gemma Vilagut

“…Multilevel reliability and intraclass correlation coefficients were obtained for positive and negative affect measures. …”
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Reconstructing prevalence dynamics of wildlife pathogens from pooled and individual samples by Borremans, Benny, Falvo, Caylee A, Crowley, Daniel E, Hoegh, Andrew, Lloyd-Smith, James O, Peel, Alison J, Restif, Olivier, Ruiz-Aravena, Manuel, Plowright, Raina K

“…If these biases are taken into account, the concentration of a pooled sample can be leveraged to infer the most likely proportion of positive individuals, and thus improve overall prevalence reconstruction, but few methods exist that account for the sample mixing process. …”
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Programmatic mapping and size estimation of people who inject drugs to plan targeted HIV prevention and harm reduction programs in iran, a nationwide study by Nima Ghalekhani, Ahmad Hajebi, Ebrahim Ghodusi, Behnaz Beygi, Toktam Khojasteh Bojnordi, Mohammad Farooq Mashhour, Fatemeh Rezaei Sharif, Farzaneh Rajabzadeh, Hooriyeh Khoshdel, Hamid Reza Fathi, Hamid Sharifi

“…Methods A cross-sectional key informant-driven mapping and enumeration methodology was used to identify hotspots of illicit drug use in 82 cities across 24 provinces in Iran from August 2020 to March 2021. …”
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