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13441
Harnessing Meta-Reinforcement Learning for Enhanced Tracking in Geofencing Systems
Published 2025-01-01“…Our proposed meta-RL method addresses the NP-hard problem of determining an optimal placement of 5G Points to minimize spatial geometry-induced errors. …”
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13442
Comparative analysis of capillary threshold pressure measurement techniques: mercury intrusion porosimetry vs. innovative measuring tool for carbon storage
Published 2025-02-01“…Underestimation of threshold pressure can have significant consequences for the design and safety of CO2 storage projects, as this parameter is essential to assess the sealing efficiency of the caprocks and determine the storage capacity.…”
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13443
Global Energy Systems Modeling: Structure and Environmental Impacts
Published 2025-04-01“…Statistical analysis reveals robust correlations between primary energy consumption and environmental indicators, with correlation coefficients exceeding 0.9. The research demonstrates that primary energy consumption patterns and fuel balance structure, rather than emission volumes directly, are primary determinants of environmental impact. …”
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13444
Detection of frictional meltwater on snow surface using a humidity indicator
Published 2024-09-01“… Introduction & Purpose The low friction coefficient of a ski on snow is due to the formation of a meltwater layer between the ski base and the snow surface. …”
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13445
Study on the Radial Displacement Law and Permeability Enhancement Effect of Coal Body around Hydraulic Flushing Drilling
Published 2021-01-01“…Therefore, this article comprehensively uses laboratory experiments, numerical simulations, and field practices to fully explain the hydraulic flushing pressure relief mechanism and proposes a method to accurately determine the pressure relief range based on the radial line strain law. …”
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13446
AI-Based Noise-Reduction Filter for Whole-Body Planar Bone Scintigraphy Reliably Improves Low-Count Images
Published 2024-11-01“…<b>Methods</b>: The performance of the AI bone-scan filter (BS-AI filter) in question was retrospectively evaluated on 47 different patients’ <sup>99m</sup>Tc-MDP bone scintigraphy image pairs (anterior- and posterior-view images), which were obtained in such a manner as to represent the diverse characteristics of the general patient population. …”
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13447
7aaRGD - a novel SPP1/integrin signaling-blocking peptide reverses immunosuppression and improves anti-PD-1 immunotherapy outcomes in experimental gliomas
Published 2025-04-01“…We hypothesized that a combination strategy aiming to block the reprogramming of GAMs using a synthetic 7aaRGD peptide that targets SPP1/integrin signaling might overcome resistance to ICIs and reinvigorate anti-tumor immunity. Methods Matrigel invasion assay was used to test the efficacy of 7aaRGD in glioma-microglia co-cultures. …”
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13448
Myocardial work in electrical dyssynchrony due to left bundle branch block
Published 2025-03-01“…To evaluate myocardial function in different groups of patients with left bundle branch block (LBBB) and the LBBB "model" — right ventricular pacing (RVP).Material and methods. Global longitudinal strain (GLS) and myocardial function parameters, such as global constructive work (GCW), global wasted work (GWW), global work index (GWI), and global work efficiency (GWE), were measured in 25 patients with dilated cardiomyopathy (DCM) and LBBB (DCM-LBBB group), 20 patients with DCM and a narrow QRS complex (DCM-nonLBBB group), 15 patients with LBBB developed after transcatheter aortic valve implantation (TAVI LBBB group), 12 patients with idiopathic LBBB (I-LBBB group), 27 patients with permanent RVP, and 10 healthy volunteers (HVs). …”
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13449
Subsurface cavity detection in a karst environment using electrical resistivity (er): a case study from yongweol-ri, South Korea
Published 2012-10-01“…A numerical modelling study preceded the field survey to determine whether the electrical resistivity method could identify such features. …”
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13450
Business Model Innovation through the Expansion of Digital Platforms
Published 2024-12-01“…Methodology This research employs the Delphi method to identify and analyze key drivers. The Delphi method is a systematic technique used to collect and align expert opinions through multiple rounds of questionnaires without direct interaction among participants. …”
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13451
Pharmacoeconomic aspects of the targeted drugs use in psoriatic arthritis in context of the Russian healthcare system
Published 2022-10-01“…Objective: to study the clinical and economic aspects of the use of biological disease modifying antirheumatic drugs (bDMARDs) and targeted synthetic DMARDs (tsDMARDs), Janus kinase inhibitors (JAKi), for the treatment of psoriatic arthritis (PsA).Patients and methods. The study included adult patients (age ≥18) with active PsA, bionaive or previously treated with bDMARDs. …”
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13452
The effectiveness of cardiac resynchronization therapy in patients with chronic heart failure of various origin depending on the structural myocardial injury in cardiac magnetic re...
Published 2019-12-01“…To assess the effect of the size and pattern of myocardial structural injury, determined by magnetic resonance imaging (MRI), on response to cardiac resynchronization therapy (CRT) in patients with ischemic and non-ischemic heart failure (HF).Material and methods. …”
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13453
Uptake of DU145 and LNCaP prostate cancer cell line derived extracellular vesicles is inversely correlated with blood–brain barrier integrity in vitro
Published 2025-07-01“…This study investigated the interaction and effects of sEVs derived from low (LNCaP) and moderately metastatic (DU145) prostate cancer (PCa) cell lines with the human brain endothelial cell line hCMEC/D3. Methods Systematic optimization of the cell culture membrane insert set-up for sEV transport studies was accomplished with inserts with different pore sizes, varied coating procedures and medium compositions. …”
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13454
Exploring the clinical value of procalcitonin, c-reactive protein, white blood cell count, and neutrophil-to-lymphocyte ratio in the early diagnosis of bloodstream infections in ch...
Published 2025-01-01“…Therefore, we investigated the clinical value of procalcitonin (PCT), C-reactive protein (CRP), white blood cell count (WBC), and neutrophil-to-lymphocyte ratio (NLR) in the early diagnosis of BSI in children. Methods This study included a retrospective analysis of 309 suspected BSI cases and patients were categorized into 2 groups based on blood culture results: blood culture-positive group, and blood culture-negative group. …”
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13455
Experience with long-term infliximab therapy in patients with ankylosing spondylitis
Published 2010-12-01“…The duration of continuous use of infliximab is more than 8 years in patients with ankylosing spondylitis (AS). The efficiency of the drug persists in most patients during its long-term regular therapy. …”
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13456
INVESTIGATION OF IMMUNOGENICITY AND SAFETY OF 23-VALENT POLYSACCHARIDE PNEUMOCOCCAL VACCINE IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS
Published 2018-09-01“…Objective: to investigate the safety and immunogenicity of 23-valent polysaccharide pneumococcal vaccine (PPV-23) in patients with systemic lupus erythematosus (SLE). Subjects and methods. The investigation enrolled 30 patients with a reliable diagnosis of SLE; of them there were 27 women and 3 men at the age of 19 to 62 years. …”
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13457
Robot-assisted laparoscopic ureteropelvic junction plasty in children using the da Vinci Xi robotic system: a Russian first experience
Published 2025-06-01“…To conduct a comprehensive analysis of the experience in performing RALP in pediatric patients using the da Vinci Xi robotic platform. Materials & methods. Between July and October 2024, a total of 14 robot-assisted laparoscopic pyeloplasties (RALP) were successfully performed. …”
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13458
CHANGES OF CYTOKINE LEVELS DURING THERAPY WITH METHOTREXATE AND ADALIMUMAB IN PATIENTS WITH EARLY RHEUMATOID ARTHRITIS (REMARCA STUDY)
Published 2014-06-01“…Objective: to estimate changes in cytokine profile versus disease activity in patients with early rheumatoid arthritis (RA) who use methotrexate (MTX) and adalimumab (ADA) in accordance with the treat-to-target concept. Subjects and methods. Forty-five patients (35 women; median age 53.5 [46; 59.5] years) with early RA (median dura- tion 7.0 [4.0; 11.5] months; DAS28 5.8 [4.9; 6.4]; rheumatoid factor positivity (RF+) 91%; anti-cyclic citrullinated peptide antibody positivity (ACCP) + 96%) were examined. …”
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13459
Cognitive link adaptation via modulation scheme classification in narrowband networks under AWGN and SUI channel conditions
Published 2025-07-01“…This method first predicts the modulation type (e.g., PSK, FSK, CPM), and subsequently determines the optimal parameters (M, h, L) corresponding to the identified channel conditions. …”
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13460
Effect of feeding mechanically processed alfalfa silage on production performance of mid-lactation dairy cows
Published 2025-01-01“…ABSTRACT: Improving the digestibility and utilization of feedstuffs through processing methods may result in improved production and efficiency of dairy cattle. …”
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