Exploring Inflammatory Bowel Disease Discourse on Reddit Throughout the COVID-19 Pandemic Using OpenAI’s GPT-3.5 Turbo Model: Classification Model Validation and Case Study by Tyler Babinski, Sara Karley, Marita Cooper, Salma Shaik, Y Ken Wang

“…ObjectiveThis study aims to analyze community posts from 3 of the largest IBD support groups on Reddit between March 1, 2020, and December 31, 2022, using a pretrained transformer model, and to validate the classification system’s results via comparison to human scoring. MethodsWe collected posts (N=53,333) from subreddits r/CrohnsDisease, r/UlcerativeColitis, and r/IBD and classified them using OpenAI’s GPT-3.5 Turbo model to determine sentiment, categorize topics, and identify demographic information and mentions of the COVID-19 pandemic. …”
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SIGLEC1 has the potential to be an immune-related prognostic indicator in colon adenocarcinoma: a study based on transcriptomic data and Mendelian randomization analysis by Jue Gu, Yaxuan Wang, Hui Zhang, Haijuan Gu, Haixia Zhu

“…There are currently no specific studies indicating the mechanism of action of TME in COPD patients. Methods The percentage of tumor-infiltrating immune cells (TIC) in 512 COAD cases from The Cancer Genome Atlas (TCGA) database was calculated using CIBERSORT and ESTIMATE. …”
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The association of public health interventions regarding both infant sleep position and pertussis immunization with sudden infant death syndrome rates: an ecological study by Jacqueline Müller-Nordhorn, Amir Hakimhashemi, Stefan N. Willich, Sylvia Binting, Thomas Keil

“…We used multilayer and multivariate correlation analyses to determine the correlation between SIDS and pertussis hospitalization rates, including Pearson correlation test and vector autoregressive (VAR) analysis. …”
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The Impact of Investors' Emotional Decision Patterns on Firm Performance by Seyed Abbas Hashemi, Alireza Rahrovi Dastjerdi, Mohammad Heydarian

“…Objective: The efficient market hypothesis is based on the assumption that investors behave rationally, but studies in behavioral finance have contradicted this notion. …”
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AI-Enhanced 3D Models in Global Virtual Reality Case Conferences for Surgical Care in a Low-Income Country: Exploratory Study by Miriam Obst, Jan Arensmeyer, Henrik Bonsmann, Andreas Kolbinger, Joel Kigenyi, Francis Oneka, Benard Owere, Joachim Schmidt, Philipp Feodorovici, Jan Wynands

“…The process was time-efficient, with a total of under 8 minutes per case for data acquisition and model creation, and resource-efficient with surgeons reporting sufficient quality of smartphone-derived models. …”
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From immune evasion to broad in silico binding: computational optimization of SARS-CoV-2 RBD-targeting nanobody by Shuyuan Cao, Bo Sun, Feng Gao, Feng Gao, Feng Gao

“…This study uses molecular dynamics (MD) simulations to analyze the immune evasion mechanisms of class 1 nanobodies against emerging SARS-CoV-2 variants, and to develop an efficient in silico pipeline for rapid affinity optimization.MethodsWe employed MD simulations and binding free energy calculations to investigate the immune evasion mechanisms of four class 1 nanobodies (R14, DL4, VH ab6, and Nanosota9) against wild-type (WT) and Omicron variants, including BA.2, JN.1, and KP.3/XEC. …”
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Clinical correlation between intestinal flora profiles and the incidence of postmenopausal osteoporosis by Cuifeng Zhu, Yuan Zhang, Yi Pan, Zhentian Zhang, Yan Liu, Xiuping Lin, Jinchuan Cai, Zhuang Xiong, Yong Pan, Hezhongrong Nie

“…Purpose This study aimed to explore the characteristics of intestinal microflora polymorphism in postmenopausal women, and to determine the pathophysiological changes of gene polymorphism of intestinal flora and bone metabolism in postmenopausal osteoporosis (PMOP) patients.Methods A total of 104 postmenopausal women with PMOP or normal bone density were included. …”
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Leveraging Big Data for Economic Stability: A Dashboard for ASEAN's Future Growth by Norfiza Ibrahim, Nurul Athirah Aziz, Azmi Abu Seman, Nadia Abdul Wahab, Aznoora Osman, Siti Sarah Md Ilyas

“…The primary goals of this research are to determine the techniques and requirements of an economic stability indicator dashboard for ASEAN countries, to create a console utilizing Big Data methods and to assess the usefulness of this system. …”
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Investigation of cell development and tissue structure network based on natural Language processing of scRNA-seq data by Suwen Wei, Yuer Lu, Peng Wang, Qichao Li, Jianwei Shuai, Qi Zhao, Hai Lin, Yuming Peng

“…This multi-scale analysis includes mapping cell states in vector space to reveal developmental trajectories, quantifying cell similarity using Euclidean distance, and constructing inter-tissue relationship networks from aggregated cell vectors. Conclusions This method offers a computationally efficient approach for analyzing scRNA-seq data by constructing embedding representations similar to those used in large language model pre-training, but without requiring high-performance computing clusters. …”
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Density-Aware DETR With Dynamic Query for End-to-End Tiny Object Detection by Xianhang Ye, Chang Xu, Haoran Zhu, Fang Xu, Haijian Zhang, Wen Yang

“…This dynamic query mechanism enables efficient and accurate tiny object detection under both dense and sparse object distributions. …”
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Finding order in measuring disorders: Measurement Uncertainty of Thyroid Function Tests at a tertiary care hospital in Eastern India by Asis Bhattacharya, Kasturi Mukherjee, Arkajit Dasgupta, Debi Mallick, Mousumi Mukhopadhyay

“…Thyroid disorders constitute a global health menace but can be efficiently managed if diagnosed early via reliable immunoassays. …”
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COTI-2 suppresses the malignancy of bladder cancer by inducing apoptosis via the AMPK-mTOR signaling pathway by Yuancai Zheng, Keqi Wang, Chenyu Wu, Yuying Qin, Yihan Sun, Xinyu Lu, Yupeng Xu, Gonghui Li

“…Moreover, it efficiently suppressed the migration and invasion of BCa cells. …”
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Optimized hybrid machine learning framework for early diabetes prediction using electrogastrograms by Paramasivam Alagumariappan, Malathy Sathyamoorthy, Rajesh Kumar Dhanaraj, K. Kamalanand, C. Emmanuel, Sarah Allabun, Manal Othman, Masresha Getahun, Ben Othman Soufiene

“…Also, the Explainable Artificial Intelligence (XAI) especially SHapley Additive exPlanations (SHAP) and Meta-Heuristics based feature selection methods are utilized to determine the prominent EGG signal features. …”
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Analysis of Factors Influencing the Development of Community-Based Tourism in Rural Areas, Case Study: Villages Targeted by Tourism in the Markazi Province by Hamid Afshari, Behrouz Mohammadi Yeganeh, Hossein Farahani, Mehdi Cheraghi

“…To determine the research samples, the purposeful and snowball sampling methods were used and the sampling was done in a period of 2 months. …”
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Effect of Relative Isometric Strength on Countermovement Jump Performance in Professional and Semi-Professional Soccer Players by Nicholas Joel Ripley, Jack Fahey, Nabil Hassim, Paul Comfort

“…A series of one-way Bayesian independent <i>t</i>-tests were performed to determine the difference between strong and weak groups. …”
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The accuracy of ultrasonography for detection of enlarged parathyroid glands in patients with different forms of hyperparathyroidism by Stefanović Dara, Petrović Milan, Dugonjić Sanja

“…Ultrasonography is a cheap, easily available and convenient method for diagnosis. The aims of this study were: to determine the utility of ultrasonography for preoperative identification and localization of enlarged parathyroid glands (PTG) in patients with different forms of hyperparathyroidism (HPT); to examine the frequency of PTG detection in patients previously non-suspected for HPT but having symptoms relevant to the disease; to determine sensitivity and positive predictive value (PPV) of ultrasonography for identification of PTG in HPT and to compare obtained results with those obtained by scintigraphy. …”
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Experiences and Expectations of Immigrant and Nonimmigrant Older Adults Regarding eHealth Services: Qualitative Interview Study by Maedeh Ghorbanian Zolbin, Sari Kujala, Isto Huvila

“… BackgroundThe emergence of eHealth services could contribute to improving individuals’ quality of life by optimizing effective and efficient care. However, various challenges might limit some older adults’ use of eHealth services. …”
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Characterizing spatial epidemiology in a heterogeneous transmission landscape using the spatial transmission count statistic by Leke Lyu, Gabriella Veytsel, Guppy Stott, Spencer Fox, Cody Dailey, Lambodhar Damodaran, Kayo Fujimoto, Pamela Brown, Roger Sealy, Armand Brown, Magdy Alabady, Justin Bahl

“…Intensive and widespread efforts to collect and sequence SARS-CoV-2 viral samples have enabled the development of comparative genomic approaches to reconstruct spatial transmission history and understand viral transmission across different scales. Methods We proposed the spatial transmission count statistic that efficiently summarizes the geographic transmission patterns imprinted in viral phylogenies. …”
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Differential Neutralization Profiles of 17DD Vaccinated Population to 17D-204 and 17DD Vaccine Strains by Ana C. B. Terzian, Sasha R. Azar, Cassia F. Estofolete, Mauricio L. Nogueira, Nikos Vasilakis

“…Their functional differences in the neutralization profiles are not known. <b>Methods</b>: The Plaque Reduction Neutralization Test (PRNT) was used to determine the neutralization profiles of sera from 209 patients that were previously vaccinated with the 17DD strain against both 17D-204 and 17DD. …”
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Preparation, characterization and antioxidative activity analysis of recombinant humanized collagen type III-loaded liposomes by Mengxing Du, Chuanxiu Chen, Yuxin Zhou, Yixuan Song, Shan Wang, Shanshan Tang, Jia Yang, Xia Yang, Enli Liu, Yufeng Yu

“…Our study provides a more stable and efficient strategy for the application of rhCol.…”
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