Synergistic Drivers of Vegetation Dynamics in a Fragile High-Altitude Basin of the Tibetan Plateau Using General Regression Neural Network and Geographical Detector by Yanghai Duan, Xunxun Zhang, Hongbo Zhang, Bin Yang, Yanggang Zhao, Chun Pu, Zhiqiang Xiao, Xin Yuan, Xinming Pu, Lun Luo

Get full text

Simple water vapor sampling for stable isotope analysis using affordable valves and bags by A. Dahlmann, A. Dahlmann, J. D. Marshall, D. Dubbert, M. Hoffmann, M. Dubbert

“…More recently, samples have been collected with gas-permeable membranes (GPMs) and measured in the field. These new methods, however, present challenges in achieving high-resolution measurements across multiple sites since they require significant effort and resources. …”
Get full text

Development and validation of a novel scoring model for predicting underlying intracranial atherosclerosis prior to endovascular treatment in acute posterior circulation large-vess... by Guoyi Peng, Guoyi Peng, Guoyi Peng, Chuming Huang, Jiaqi Huang, Qiuhui Shi, Wei Xu, Shiwei Luo, Jiong Yang, Shouxing Wang, Qiao Wu, Chuwei Cai, Hao Long, Hao Long

“…The aim of this study was to develop and validate a novel scoring model to predict intracranial atherosclerosis-related large-vessel occlusion (ICAS-LVO) in patients with acute vertebrobasilar artery occlusion.MethodsThe derivation cohort comprised 170 patients who received EVT between January 2018 and June 2024 at multiple centers. …”
Get full text

A Novel 14-Gene Panel Associated With Efferocytosis for Predicting Pancreatic Cancer Prognosis Through Bulk and Single-Cell Databases by Yaheng Wu, Lin Zhao, Dingyan Yi, Zhihua Tian, Bin Dong, Chunxiang Ye, Jingtao Liu, Huachong Ma, Wei Zhao

“…Finally, we utilized experimental methods, including Boyden chamber analyses, immunohistochemical staining, and cell cycle analyses, to demonstrate that interference with ASPH suppresses the malignant properties of tumors, including proliferation and migration. …”
Get full text

Dark-field radiography for the detection of bone microstructure changes in osteoporotic human lumbar spine specimens by Jon F. Rischewski, Florian T. Gassert, Theresa Urban, Johannes Hammel, Alexander Kufner, Christian Braun, Maximilian Lochschmidt, Marcus R. Makowski, Daniela Pfeiffer, Alexandra S. Gersing, Franz Pfeiffer

“…We explored the potential of dark-field imaging of bone microstructure to improve the assessment of bone strength in osteoporosis. Methods We prospectively examined 14 osteoporotic/osteopenic and 21 non-osteoporotic/osteopenic human cadaveric vertebrae (L2–L4) with a clinical dark-field radiography system, micro-computed tomography (CT), and spectral CT. …”
Get full text

Mapping EQ-5D-5L Score From SGRQ in Patients with Asthma and/or COPD in NOVELTY by Jackson D, Quinton A, Zhang F, Müllerová H, Janson C, Sadatsafavi M

“…Starkie et al proposed an algorithm for mapping the SGRQ to EQ-5D-5L, a preference-based utility measure, in chronic obstructive pulmonary disease (COPD) (Value Health 2011;14:354– 60); only SGRQ total score, its squared value, and sex were included as covariates. We aimed to determine if including additional covariates could improve the performance of this algorithm type and whether amendments were required to extend this mapping to asthma or asthma+COPD.Patients and Methods: SGRQ and EQ-5D-5L were measured from a large, global, prospective, longitudinal study in asthma and/or COPD (NOVELTY; NCT02760329). …”
Get full text

Long‐term cardiovascular outcomes of immune checkpoint inhibitor‐related myocarditis: A large single‐centre analysis by Lorenzo Braghieri, Ahmad Gharaibeh, Lubika Nkashama, Abdelrahman Abushouk, Osama Abushawer, Amir Mehdizadeh‐Shrifi, Bianca Honnekeri, Cassandra Calabrese, Venu Menon, Pauline Funchain, Patrick Collier, Diego Sadler, Rohit Moudgil

“…Patients and methods The ICI‐related adverse event (irAE) registry was queried to identify irM patients by using Bonaca criteria. …”
Get full text

Complete genome sequence, metabolic profiling and functional studies reveal Ligilactobacillus salivarius LS-ARS2 is a promising biofilm-forming probiotic with significant antioxida... by Sinjini Patra, Biswaranjan Pradhan, Anasuya Roychowdhury

“…Here, we illustrate probiotic attributes of novel LS-ARS2 for its potential application as food-supplement and/or therapeutic to improve gut-health.MethodsWhole genome sequencing (WGS) and phylogenetic analysis confirm the strain as LS. …”
Get full text

ACUTE TOXICITYOF 4-AMINO-5-(2-, 3-, 4-NITROPHENYL)-1,2,4-TRIAZOLE-3-THIONES AND ITS DERIVATIVES by М. O. Shcherbak, А. G. Kaplaushenko, I. F. Belenichev

“…The aim of our work was to generalize relative dependence of pharmacological activity of synthesized compounds on their structure. Materials and methods. The research has been conducted by the V.B.Prozorovskiymethod on white Wistar rats. …”
Get full text

People Living with HIV's Worry That the COVID-19 Health Crisis Could Impact Long-Term HIV Care: Lessons From the French Context for Future Disease Epidemics by M. Salcedo PhD, T. Alain MA, C. Lacoux MA, J.C. Jones MA, C. Della Vecchia PhD, N. Charpentier MA, R. Mabire-Yon PhD, L. Vallet MA, X. Mabire PhD, D. Ferraz PhD, D. Michels PhD, M. Préau PhD

“…Using data from the anonymous, online, cross-sectional survey ACOVIH, which was completed by PLHIV between July and September 2020, this study explored factors associated with worry about long-term changes to HIV care after the end of the first lockdown (17 March-11 May 2020). Methods: Using multivariate logistic regression, we compared participants who declared they were worried about long-term changes with those who did not, in terms of their demographic, behavioral, and socioeconomic characteristics, as well as their experience of the COVID-19 crisis and access to care. …”
Get full text

Availability and readiness of public health facilities to provide differentiated service delivery models for HIV treatment in Zambia: implications for better treatment outcomes by Patrick Kaonga, Mutale Sampa, Mwiche Musukuma, Mulanda Joseph Mulawa, Mataanana Mulavu, Doreen Sitali, Given Moonga, Oliver Mweemba, Tulani Francis Matenga, Cosmas Zyambo, Twaambo Hamoonga, Henry Phiri, Hikabasa Halwindi, Malizgani Paul Chavula, Joseph Mumba Zulu, Choolwe Jacobs

“…We aimed to assess the availability of HIV service indicators and the readiness of facilities to provide DSD models for HIV treatment in selected public health facilities in Zambia.MethodsWe conducted a nationwide cross-sectional survey among public health facilities in Zambia that provide antiretroviral therapy (ART) services. …”
Get full text

Lifestyle factors and urine levels of organophosphorus flame retardants in endometrial cancer: insights from a case-control study by Yu-Che Ou, Fu-Jen Cheng, Wan-Ting Huang, Wen-Chin Lee, Hung-Chun Fu, Chen-Hsuan Wu, Ying-Yi Chen, Kuo-Chung Lan, Xuan-Ping Liou, Hao Lin, Chia-Te Kung

“…This study aimed to investigate the association between urine levels of OPFRs and endometrial cancer (EC), and to explore the correlation between concentrations of parent OPFR compounds and their metabolites. Methods: Urine samples from 76 EC patients and 76 healthy controls were collected and analyzed for the levels of five common parent OPFRs and their respective metabolites. …”
Get full text

Gender and age-related variations in rumen fermentation and microbiota of Qinchuan cattle by Yueting Pan, Huaxuan Li, Juze Wang, Xiaolei Sun, Entang Liang, Juntao Guo, Jianfang Wang, Ke Zhang, Bingzhi Li, Mengqi Zan, Wucai Yang, Linsen Zan

Get full text

Laser peripheral iridotomy in patients with acute primary angle closure by Paunović Svetlana, Paunović Milan, Srečković Sunčica, Petrović Nenad, Jovanović Mihailo, Todorović Dušan, Šarenac-Vulović Tatjana

“…Methods. The research included 40 patients and 80 eyes treated between 2017 and 2021, which was also the follow-up period in the study. …”
Get full text

In Vitro Characterization of the Immune Response to an Epitope Ensemble Vaccine Against Rhinovirus in Pediatric Asthma and Adults With Chronic Obstructive Pulmonary Disease: Protoc... by Sara Alonso Fernandez, Raquel Reyes-Manzanas, Susana Camara, Juan Mozas-Gutierrez, Myriam Calle-Rubio, Juan Rodriguez-Hermosa, Andres Bodas-Pinedo, Santiago Rueda Esteban, Esther M Lafuente, Jesús Reiné, Pedro A Reche

“…MethodsParticipants with asthma and those with COPD, aged 5-15 and 40-70 years, respectively, will be recruited alongside healthy age-matched controls. …”
Get full text

Agreement and utility of coded primary and secondary care data for long-term follow-up of clinical trial outcomes by Ariel Wang, Anna E Seeley, Matthew R Sydes, Nicholas Jones, Simon de Lusignan, FD Richard Hobbs, Richard J McManus, Marney Williams, James P Sheppard

“…Abstract Background Whilst interest in efficient trial design has grown with the use of electronic health records (EHRs) to collect trial outcomes, practical challenges remain. …”
Get full text

Development of armored products made from multilayer composite plates by Lyubov A. Bokhoeva, Vitaly E. Rogov, Elena B. Bochektueva, Aldar B. Baldanov, Roman P. Ivanov

“…The article discusses the development of multilayer plates made from composite materials for personal and light armor protection. Methods and materials. Multilayer structures, including UHMWPE and aramid fabrics, were used to create armor plates. …”
Get full text

Deep-learning prediction of cardiovascular outcomes from routine retinal images in individuals with type 2 diabetes by Mohammad Ghouse Syed, Emanuele Trucco, Muthu R. K. Mookiah, Chim C. Lang, Rory J. McCrimmon, Colin N. A. Palmer, Ewan R. Pearson, Alex S. F. Doney, Ify R. Mordi

“…Methods We included 6127 individuals with type 2 diabetes without myocardial infarction or stroke prior to study entry. …”
Get full text

A WeChat-Based Decision Aid Intervention to Promote Informed Decision-Making for Family Members Regarding the Genetic Testing of Patients With Colorectal Cancer: Randomized Control... by Huanhuan Li, Yanjie Zhao, Wei Li, Wenxia Wang, Shengze Zhi, Yifan Wu, Qiqing Zhong, Rui Wang, Jiao Sun

“…MethodsA single-center, parallel-group, randomized controlled trial was conducted. …”
Get full text

Postreperfusion Renal Allograft Biopsy Predicts Outcome of Single-Kidney Transplantation: A 10-Year Observational Study in China by Meifang Wang, Junhao Lv, Jie Zhao, Huiping Wang, Jianghua Chen, Jianyong Wu

“…We investigated the predictive value of postreperfusion biopsy on long-term allograft outcome after single-kidney transplantation. Methods: We retrospectively evaluated the significance of histologic findings, read by experienced renal pathologists, in 461 postreperfusion biopsy specimens collected from 2010 to 2017 after deceased donor renal transplant; and performed time-to-event analyses to determine the association between histology and hazard of death-censored graft failure. …”
Get full text