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14081
7aaRGD - a novel SPP1/integrin signaling-blocking peptide reverses immunosuppression and improves anti-PD-1 immunotherapy outcomes in experimental gliomas
Published 2025-04-01“…We hypothesized that a combination strategy aiming to block the reprogramming of GAMs using a synthetic 7aaRGD peptide that targets SPP1/integrin signaling might overcome resistance to ICIs and reinvigorate anti-tumor immunity. Methods Matrigel invasion assay was used to test the efficacy of 7aaRGD in glioma-microglia co-cultures. …”
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14082
Recuperação de solos afetados por sais pela aplicação de gesso de jazida e calcário no Nordeste do Brasil Reclamation of salt-affected soils in Northeast Brazil with application of...
Published 2004-04-01“…In the saturation extract the electrical conductivity and the soluble cations were determined. The application of gypsum and the mixture of gypsum + limestone showed to be efficient for correction of soil sodicity, which was indicated by a positive effect on the physical and chemical characteristics of the soils, therefore these may be recommended as calcium source for the reclamation of the saline-sodic soils. …”
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14083
Investigating the relationship between the monetary policy shock through the exchange rate channel on the management quality index in the banking system: by examining the productiv...
Published 2025-03-01“…The current research is applied in terms of its purpose and analytical-descriptive in terms of its method. This study utilizes 96 variables of seasonal time series data that affect the management quality index within the bank productivity framework, one of the critical indicators for assessing the health of the banking system. …”
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14084
Grape Value Chain Analysis with Emphasis on Raisin Crop in Hamedan Province
Published 2025-03-01“…Various methods exist for analyzing the value chain, with the SWOT analysis (identifying strengths, weaknesses, opportunities, and threats, as well as determining strategic positioning) being the most significant. …”
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14085
In Vitro Effect of Ferruginol, Tanshinone, and Carnosol Analogues on the Proliferation of Three Breast Cancer Cell Lines
Published 2025-06-01“…The compounds that were synthesized underwent a methodical evaluation using multiple biological tests (including viability assays, clonogenic assays, and mitochondrial membrane polarization measurements) to determine their ability to inhibit in vitro the growth of three breast cancer cell linages. …”
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14086
A Diffusive Predator-Prey System with a Free Boundary
Published 2025-04-01“…Nonlinear problems with free boundary are studied using a method based on constructing a priori estimates. Therefore, first, using a method based on constructing a priori estimates, we will determine the constraints on the parameters of the problem, under which it is globally solvable. …”
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14087
Multitarget Direct Localization Using Block Sparse Bayesian Learning in Distributed MIMO Radar
Published 2015-01-01“…Since the sparse representation coefficients exhibit block sparsity, we use a block sparse Bayesian learning (BSBL) method to estimate the locations of multitarget, which has many advantages over existing block sparse model based algorithms. …”
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14088
Automated synthesis of technological fixture constructions
Published 2019-12-01“…Automated synthesis of fixtures is considered in this article. A method for determining the design situation is proposed. …”
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14089
Psychometric properties and meaningful change thresholds for the QOL-E instrument in patients with myelodysplastic neoplasms
Published 2025-02-01“…The objective of this study was to evaluate the psychometric performance of the QOL-E in patients with LR-MDS.MethodsData from four clinical trials in MDS (MEDALIST, DARB-MDS, EQoL-MDS, and RevMDS trials) were used to assess construct validity, reliability, and responsiveness. …”
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14090
Anisotropic temperature-dependent lattice parameters and elastic constants from first principles
Published 2025-08-01“…By replacing the costly multidimensional minimization with a gradient-based method that leverages second-order derivatives of the vibrational free energy, the number of required phonon band structure calculations is significantly reduced: only six are needed for hexagonal, trigonal, and tetragonal systems, and 10–28 for lower-symmetry systems to determine the temperature dependence of lattice parameters and thermal expansion. …”
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14091
Computer-measuring system of the induction motor’s dynamical torque-speed characteristics
Published 2019-06-01“… In the article an efficient method of determining the dynamic torque-speed characteristic of induction motors and the computer-measuring system for its realization is considered. …”
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14092
Quantitative Identification of Adulterated Sichuan Pepper Powder by Near-Infrared Spectroscopy Coupled with Chemometrics
Published 2017-01-01“…The determination coefficients of prediction set (Rp2) with the best pretreatments were 0.971 for Sichuan pepper powder, 0.948 for rice bran, 0.969 for wheat bran, 0.967 for corn flour, and 0.994 for rosin powder, respectively. …”
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14093
The Role of Product Quality and Price in Shaping Consumer Purchasing Decisions at Harvest Chicken Express Glenmore
Published 2024-06-01“…Sampling technique with non-probability sampling technique and incidental sampling approach Multiple linear regression analysis techniques, multiple determination coefficients, F and t-tests, validity test, reliability test, and classic assumption test (normality test, multicollinearity, and heteroscedasticity) Tests were carried out with the IBM SPSS Statistics 25 software analysis tool. …”
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14094
Ovarian ROS-dependent IgG accumulation precedes lipofuscin deposition and follicular decline: comparative insights from the bitch and mouse models of ovarian aging
Published 2025-05-01“…Immunohistochemistry was employed to determine IgG deposition and western blotting for its quantification. …”
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14095
Unsupervised clustering of temporal patterns in high-dimensional neuronal ensembles using a novel dissimilarity measure.
Published 2018-07-01“…SPOTDisClust does not require binning and can detect complex patterns (beyond sequential activation) even when high levels of out-of-pattern "noise" spiking are present. Our method handles efficiently the additional information from increasingly large neuronal ensembles and can detect a number of patterns that far exceeds the number of recorded neurons. …”
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14096
Human Resource Information System with Machine Learning Integration
Published 2022-06-01“…Based on the thorough evaluation of the experts and respondents, it was found that the human resource information system is highly usable, secured, efficient, and provides a fast and easy way to manage employees' records and predict employees over using a supervised machine learning that uses the linear regression method. …”
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14097
A Cooperative Trajectory Optimization Algorithm for Connected Vehicles in Merging Zones
Published 2022-01-01“…Numerical experiments validate that the proposed method guarantees safe driving and provides relatively smooth trajectories to the vehicles. …”
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14098
Optimization Design and Experimental Verification of Type B Bogie Frame Structure Based on Workbench
Published 2019-07-01“…At the same time, the method was more efficient and more accurate than the optimal design based on experience, which could provide reference for the optimization design of other rail vehicle structures.…”
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14099
AHP-Guided Stacked Ensemble Modeling for Student Engagement Level Prediction in Online Education
Published 2025-01-01“…Second, the use of a novel feature selection method based on Analytic Hierarchy Process (AHP) and an iterative approach. …”
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14100
Gastropod and Bivalvia Diversity Using Environmental DNA (E-DNA) Techniques in The Waters of Gili Genting and Gili Labak Islands, Sumenep, Madura
Published 2025-01-01“…The method used in this study is the environmental DNA method to detect species through air samples, because it is considered an effective and efficient method. …”
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