Efficacy and safety of Cadonilimab plus anlotinib in small cell lung cancer with brain metastases by Hai-Zhen Yi, Wei Lv, Jin-Jing Chen, Zhan Lin

“…PurposeThis study aimed to evaluate the efficiency and safety of Cadonilimab and Anlotinib pairing in individuals diagnosed with small cell lung cancer (SCLC) and brain metastases (BMs).MethodsA review was performed on individuals who were diagnosed with small cell lung cancer (SCLC) and had central nervous system (CNS) metastases confirmed via magnetic resonance imaging (MRI) of the brain.We assessed the treatment response of Cadonilimab plus Anlotinib using Response Evaluation Criteria in Solid Tumors version 1.1 (RECIST 1.1) and Response assessment in neuro-oncology brain metastases (RANO-BM) for evaluating solid tumors and neuro-oncology brain metastases, respectively.The patients’ prognosis was determined using Kaplan-Meier analysis and Cox regression analysis.FindingsThe study initially included 46 patients diagnosed with SCLC who presented with brain metastases (BMs). …”
Get full text

Research Progress on Development of PVP-Ag-Doped LaMnO₃ Composites for Methyl Orange Degradation by Adina Căta, Madalina-Gabriela Ivanovici, Paula Svera, Ioana Maria Carmen Ienașcu, Paula Sfirloaga

“…The different methods used for the synthesis of the new materials influenced their features and behavior. …”
Get full text

Evaluation of the short-term efficacy and safety of biological agents in different rheumatic diseases: a multidisciplinary therapeutic hospital"s experience by N A Mukhin, P I Novikov, Sergey Valentinovich Moiseev, T M Ignatova, L V Kozlovskaya, E N Semenkova, V V Fomin, S V Gulyaev, T N Krasnova, L A Strizhakov, T N Yanushkevich, V V Panasyuk, N V Nikiforova, S V Roshchupkina, Yu D Sorokin, A D Meshkov, L V Dubrovskaya, E S Zhabina, S A Parfenova, E I Kuznetsova, I A Lopatina

“…Therapeutic efficiency and safety were evaluated 6 months later. …”
Get full text

Grain Damage in Low­Speed Collision with the Surfaces of the Hoisting­and­Transport Machines Working Parts by V. I. Pakhomov, S. V. Braginets, E. V. Benova, O. N. Bakhchevnikov, D. S. Podlesnyy

“…(Materials and methods) Experiments were carried out on a unit that reproduced the low-speed collision conditions of wheat grains with a smooth steel or plastic surface plate at various angles of incidence and the number of impacts.…”
Get full text

Cardiovascular risk profile in patients with arterial hypertension who first seek medical attention by D. V. Nebieridze, T. V. Kamyshova, A. A. Sarycheva, A. S. Safaryan

“…Objective assessment of cardiovascular risk (CVR) in patients with arterial hypertension (AH), who first contact with primary care setting.Material and methods. 300 patients (age 40-65 years) with sustained increase in arterial pressure and first seek medical attention were included in the study. …”
Get full text

Macrostructural Analysis of the Dynamics of the Two-Sector Economy by O. S. Sukharev, E. N. Voronchikhina

“…The study found that the predominance of the consumer goods sector in the Russian GDP structure not only determined the current dynamics, but also the potential for the growth rate of the capital goods sector, as well as the level of its efficiency, which affects the dynamics of prices in the sector. …”
Get full text

The effectiveness of community engagement using M-Mama champions in improving awareness of obstetric danger signs, birth preparedness and complication readiness among pregnant wome... by Alex Sanga, Stephen Kibusi, James Tumaini Kengia

“…<h4>Methods</h4>A parallel arms, cluster-randomized pragmatic implementation trial, whereby pregnant women were recruited from four clusters and randomised at a ratio of 1:1. …”
Get full text

Analysis of factors influencing doctors' awareness of clinical guidelines for heart failure treatment by N. B. Perepech, A. V. Tregubov, I. E. Mikhailova

“…To find out the relationship between the awareness level of clinical guidelines on heart failure (HF) with reduced ejection fraction and a number of professional characteristics (specialty, work experience, self-assessment of awareness level, attitude towards the use of guidelines, the main way of document study). To improve the efficiency and development of the postgraduate education system, the factors that influence doctors' awareness of guidelines should be determined.Material and methods. …”
Get full text

Assessment of the Effectiveness of Sanatorium Treatment Resulting in the Decrease of Pain of the Lumbar Spine by Anna Antczak, Beata Haor, Agnieszka Królikowska, Renata Jabłońska

“…The aim of the study is to assess the impact of sanatorium treatment on the reduction of pain occurring in the pain syndromes of the lumbar spine. Material and Methods. The survey was conducted among 300 (100%) randomly selected patients, aged from 35 to 65 years. …”
Get full text

New medical technologies influence on the quality of medical care in megalopolises (on the example of Moscow city) by E. I. Aksenova

“…Based on the systematization of information obtained by the authors in the course of the study, authors identified the most important new medicaltechnologies for the population and health care professionals, which, in their opinion, have changed the landscape of the capital’s health care for the better. Authors determined significant criteria for improving the efficiency of the health care system through the search, comprehensive assessment and scaling of innovative practices in clinical medicine. …”
Get full text

Exploring the relationship between mental work load, work ability, and musculoskeletal disorders: A cross-sectional modeling study among health service workforces in Iran. by Maryam Rafiee, Ali Alboghobeish, Mahnaz Saremi, Sayed Vahid Esmaeili

“…<h4>Introduction</h4>The health service workforces play a crucial role in shaping a nation's health system efficiency, making it vital to understand factors affecting their performance. …”
Get full text

Citric Acid Irrigation Protocols for Bioceramic Sealers for Root Canal Retreatments by Mustafa Imad Saleh, Emad Farhan Alkhalidi

“…The percentage of the uncleaned canal areas was determined quantitatively with the use of ImageJ software. …”
Get full text

Tuberculosis in Adults and Children in the Northwestern Federal District: Changes in Epidemiological Rates and Criteria for Their Assessment by A. A. Starshinova, I. F. Dovgalyuk, D. A. Kudlay, M. V. Beltyukov, P. K. Yablonskiy

“…At the same time, the first two regions occupy this position stably from 2017 to 2021. The use of the coefficient of low coverage with screening for tuberculosis made it possible to determine that Murmansk Oblast, St. …”
Get full text

Interior Point Algorithm in Multi-objective Portfolio Optimization: GlueVaR Approach by Elaheh Gohania, Gholamreza Mansourfar, Fahimeh Biglari

“…Results According to the research, value at risk (VaR) and conditional value at risk (CVaR) perform better than other variance risk measures in the portfolio optimization model with the GlueVaR risk measure and the internal point optimization method for determining the most effective border. …”
Get full text

A FixMatch Framework for Alzheimer&#x2019;s Disease Classification: Exploring the Trade-Off Between Supervision and Performance by Al Hossain, Umme Hani Konok, MD Tahsin, Raihan Ul Islam, Mohammad Rifat Ahmmad Rashid, Mohammad Shahadat Hossain, Karl Andersson

“…We first assessed various supervised models and determined that VGG19-FFT provided the strongest balance of classification accuracy and computational efficiency. …”
Get full text

Algorithm for Selecting a Base Tractor Model to Form a Tractor Train by M. T. Toshboltaev, B. A. Kholikov

“…The studies employed the methods of implement mounting on machine-tractor units and elements of the theory of a tractor. …”
Get full text

INNOVATIVE TECHNOLOGIES OF ALCOHOLIC BEVERAGES BASED ON FRUIT DISTILLATES by E. V. Dubinina, D. V. Andrievskaya, S. M. Tomgorova, K. V. Nebezhev

“…Fermented pulp of red ashberry, distillates and alcoholic beverage blends from ashberry were used as objects of the study. To determine the organoleptic and physico-chemical indicators in the work, standardized analysis methods and certified methods were used. …”
Get full text

Identification of heavy work investment antecedents: a research on digital leadership by Burcu Turan-Torun, Onur Oktaysoy, Mehmet Selman Kobanoglu, Ethem Topcuoglu, Muhammed Akif Yenikaya, Vurgun Topcuoglu, Selen Uygungil-Erdogan

“…Within the framework of the sub-dimensions of HWI such as Time Commitment (TC) and Work Intensity (WI), the study investigates how employees’ investment in their work is shaped and the guiding role of digital leaders in this process.MethodsThis study, which aims to determine the mediating role of HWI in the effect of digital leadership on job performance, job satisfaction and career satisfaction of employees, was conducted with 393 employees working in SMEs operating in the IT sector. …”
Get full text

ANALYSIS OF STABILITY OF THE CLASSIFYING RULES PROCESSINGS OF TEXT INFORMATION by M. A. Silbergleit, A. S. Ryzhankova

“…The analysis of stability of the classifying rules is carried out on the basis of the analysis calculated for each of methods of transformation of coefficients of a variation.…”
Get full text

Programming UAV swarm operational test based on mission reliability by WANG Jingyu, JIANG Ping, XIE Dingxing, QI Jianjun

“…Then, using the multi-objective quantum particle swarm optimization algorithm, the Pareto boundary is solved and the optimal program that comprehensively considers reliability and cost is determined. Finally, a simulation case is used to verify the correctness of the proposed programming method, which is a useful exploration of UAV swarm operation trial programming.…”
Get full text