IMPAIRED REGULATORY MECHANISMS OF THE mTOR SIGNALING PATHWAY IN OSTEOARTHROSIS by Elena Vasilyevna Chetina, E A Bratygina, E M Zaitseva, E P Sharapova, A L Alekseyeva, N V Demin, S A Makarov

“…Objective: to study the pattern of impaired regulatory mechanisms of the mammalian target of rapamycin (TOR) signaling pathway, by monitoring gene expression in the blood of patients with osteoarthrosis (OA) at different stages of the disease. Subjects and methods. The study covered 33 outpatients with OA, 14 patients with this condition prior to knee joint endoprosthesis, and 27 healthy individuals (controls) (mean age 58.0+7.4, 56.5+8.9, and 55.0+8.3 years, respectively). …”
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Metronome-guided Rhythmic Auditory Stimulation with Visual Feedback for Fall Prevention in Elderly: A Randomised Controlled Trial by Abha Khisty, Zafar Azeem, Tushar Palekar

“…Materials and Methods: This randomised controlled trial was conducted at the Department of Physiotherapy, Dr. …”
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A Personalized Approach to the Treatment of Primary Open-Angle Glaucoma by A. L. Onishchenko, N. V. Maltseva, A. Sh. Smirnova, O. M. Kazantseva, S. I. Makogon

“…Aim — to study of gene polymorphisms affecting the effectiveness of timolol treatment of primary open-angle glaucoma.Patients and Methods. The study included 39 Russian patients (29 women and 10 men) aged 53 to 89 years old with a diagnosis of primary open-angle glaucoma (POAG). …”
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ESOPHAGEAL PATHOLOGY IN SCLERODERMA SYSTEMATICA: CLINICAL AND ENDOSCOPIC FINDINGS by A E Karateev, M M Movsisyan, L P Ananyeva, S G Radenska-Lopovok

“…Subjects and methods. Three hundred and fifty-six patients (women, 92.6%; men, 7.4%) aged 47.8±19.7 years with SDS and 1018 patients (women, 89.0%; men, 11.0%) aged 44.1±16.3 years with rheumatoid arthritis (RA) were examined. …”
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Machine Learning-Based Predictive Maintenance for Photovoltaic Systems by Ali Al-Humairi, Enmar Khalis, Zuhair A. Al-Hemyari, Peter Jung

“…This paper introduces an AI-based robotic cleaning system that can independently forecast and schedule cleaning sessions from real-time sensor and environmental data. Methods: The system integrates sources of data like embedded sensors, weather stations, and DustIQ data to create an integrated dataset for predictive modeling. …”
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Evaluating Key Biomotor Abilities: A Comparison between National and International Elite Tennis Players by Pratham Singh, Dharmander Kumar, Mohit Morya, Rishabh Singh, Md. Hamidur Rahman

“…Biomotor ability is essential for elite tennis players, as it significantly contributes to increased efficiency, responsiveness and overall performance on the court. …”
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Serum Transcription Factor EB Levels in Relation to Poor Neurological Prognosis and Mediation Effect of Stroke-Associated Pneumonia in Acute Intracerebral Hemorrhage: Evidence from... by Wang K, Zhan G, Jiang Q, Jiang C, Zheng G, Tang Z

“…Serum TFEB levels were measured after acute intracerebral hemorrhage (ICH), in addition to determining their connection to the severity and neurological outcomes of patients.Methods: Serum TFEB levels were measured in a prospective cohort study of 186 ICH patients and 100 controls. …”
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Menadione Sodium Bisulfite Loaded Rhamnolipid Based Solid Lipid Nanoparticle as Skin Lightener Formulation: A Green Production Beside In Vitro/In Vivo Safety Index Evaluation by Fatemeh Asadpour Panbehchouleh, Hossein Amani, Majid Saeedi

“…Purpose: In the current investigation, an ultrasonic approach was performed to produce menadione sodium bisulfite-loaded solid lipid nanoparticles (MSB-SLNs) with rhamnolipid as bio-surfactant, which aimed to increase the dermal delivery and anti-pigmentation effect. Methods: To achieve optimum delivery for MSB, the impact of the ratio of two surfactants (rhamnolipid: Tween) on nanoparticle attributes and the respective functions were evaluated. …”
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Optimal Pre-disaster and Post-disaster Scheduling of Mobile Energy Storage Considering the Influence of Transportation Network by XIE Peikun, LI Liang, SHI Yuanjie, SHENG Qing, LI Zhenkun

“…Following the disaster， a dynamic optimization scheduling model of the MES was developed for determine the optimal dynamic scheduling scheme of the MES. …”
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Production of aluminum alloys in electrolysis cells based on Hall-Héroult process: a review by ZHANG Cheng, XUE Ji-lai, LIU Xuan, LI Xiang, ZHU Jun, LIU Qiao-chu, QIAN Yi

“…Compared with the traditional alloy production methods, H-H-based processes have a great potential in improving product quality, simplifying production process, and reducing energy consumption. …”
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Manganese deficiency or dietary manganese(III) oxide nanoparticle supplementation: consequences for hematology, and intestinal and brain immunity in rats by Karolina Różaniecka-Zwolińska, Ewelina Cholewińska, Bartosz Fotschki, Jerzy Juśkiewicz, Katarzyna Ognik

“…IntroductionThe study aimed to determine the effect of manganese (Mn) exclusion from the mineral mixture added to the rat diet and replacing the recommended level of MnCO3 (65 mg Mn/kg diet) with Mn2O3 nanoparticles (Mn2O3NPs) in the diet on blood hematology and selected immunological indices of the blood, jejunum, and brain.MethodsThe experiment was conducted on twenty-four, Wistar rats divided into 3 equal groups. …”
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THE PLACE OF TOFACITINIB IN THE TREATMENT STRATEGY OF RHEUMATOID ARTHRITIS by V. I. Mazurov, E. A. Trofimov, R. R. Samigullina, I. Z. Gaidukova

“…Objective: to determine the efficiency and safety of therapy with tofacitinib (TOFA) in combination with methotrexate (MTX) in patients with active rheumatoid arthritis (RA) after insufficient previous therapy in real clinical practice.Subjects and methods. …”
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The Effect of Gender Inequality in Education on Rural Poverty in Kamuganguzi Sub-County Kabale District. by Niwamanya, Obed

“…The study engaged a total of sixty-six (66) respondents. Data collection methods and tools used to collect data included interviews and questionnaires. …”
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Credit Policy and Loan Recovery Among SACCOs In Kabale Municipality: A Case Study of Lyamujungu SACCO Kabale Municipality. by Atuheire, Dickson

“…Both simple random and purposive sampling techniques were used in identifying the study sample size. The methods that were used in data collection included questionnaires, observation, and interviews. …”
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Second-harmonic generation microscopy of murine scleral remodeling by collagenase and reparative collagen mimetic peptides by Daniel E. Savage, Daniel E. Savage, Aldo Tecse, Aldo Tecse, Jiaxi Zhou, James A. Germann, Mark R. Buckley, Mark R. Buckley, Robert O. Baratta, Brian J. Del Buono, Eric Schlumpf, Michael Telias, Michael Telias, Susana Marcos, Susana Marcos

“…This investigation is a pilot study to determine if a novel collagen mimetic peptide (CMP) has a reparative function for scleral collagen organization after collagenase digestion, a cause for scleral thinning and increased creep rates, as this may have application in the pharmacologic treatment of myopia.MethodsFresh, ex vivo, scleral tissue samples from 3 albino Sprague–Dawley rats (5 eyes) and from 8 C57/Black mice (8 eyes) underwent sequential collagenase digestion and treatment with a CMP solution. …”
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Wireless skin sensors for electrocardiogram and heart rate monitoring in the neonatal intensive care unit: a prospective feasibility, safety, and accuracy study by Eva Senechal, Daniel Radeschi, Shasha Lv, Emilie Jeanne, Ana Saveedra Ruiz, Lydia Tao, Brittany Dulmage, Wissam Shalish, Robert Edward Kearney, Guilherme Sant’Anna

“…Accuracy was measured using bias and 95% limits of agreement, and the coefficient of determination. The ability of the wireless sensors to detect normal and abnormal HR values was evaluated using a Clark Error Grid. …”
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Contrast-enhanced US Bosniak Classification: intra- and inter-rater agreement, confounding features, and diagnostic performance by Dong-dong Jin, Bo-wen Zhuang, Ke Lin, Nan Zhang, Bin Qiao, Xiao-yan Xie, Xiao-hua Xie, Yan Wang

“…Intra- and inter-rater agreements were assessed using the Gwet agreement coefficient (Gwet’s AC). Linear regression identified features associated with discrepancies in Bosniak category assignment. …”
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Development and validation of a novel scoring model for predicting underlying intracranial atherosclerosis prior to endovascular treatment in acute posterior circulation large-vess... by Guoyi Peng, Guoyi Peng, Guoyi Peng, Chuming Huang, Jiaqi Huang, Qiuhui Shi, Wei Xu, Shiwei Luo, Jiong Yang, Shouxing Wang, Qiao Wu, Chuwei Cai, Hao Long, Hao Long

“…Background and objectiveDetermining the cause of occlusion prior to endovascular treatment (EVT) for acute ischemic stroke caused by large-vessel occlusion (LVO) is helpful for developing a procedure strategy. …”
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A Novel 14-Gene Panel Associated With Efferocytosis for Predicting Pancreatic Cancer Prognosis Through Bulk and Single-Cell Databases by Yaheng Wu, Lin Zhao, Dingyan Yi, Zhihua Tian, Bin Dong, Chunxiang Ye, Jingtao Liu, Huachong Ma, Wei Zhao

“…Finally, we utilized experimental methods, including Boyden chamber analyses, immunohistochemical staining, and cell cycle analyses, to demonstrate that interference with ASPH suppresses the malignant properties of tumors, including proliferation and migration. …”
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Correlation between Sputum Cartridge-based Nucleic Acid Amplification Test–Cycle Threshold Values and Glycosylated Hemoglobin Levels in Patients with Pulmonary Tuberculosis by Chirag K C, Shashibhushan B L, Mohan J, Karthik A B

“…Materials and methods: This study, conducted over a span of 6 months, followed a cross-sectional design. …”
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