Protocol for a prospective, controlled, cross-sectional, diagnostic accuracy study to evaluate the specificity and sensitivity of ambulatory monitoring systems in the prompt detect... by Sarah Vollam, Owen Gustafson, Jody Ede, Peter J Watkinson, Akshay Shah, Matthew Rowland, Lionel Tarassenko, Cristian Roman, Philippa Piper, Louise Young, Mauro Santos, Marco A F Pimentel, Mirae Harford

“…However, a major barrier to the implementation of these wearable devices in the ward environment is their uncertain reliability, efficiency and data fidelity. The purpose of this study is to test performance of selected devices in a simulated clinical setting including during movement and low levels of peripheral oxygen saturation.Methods and analysis This is a single centre, prospective, controlled, cross-sectional, diagnostic accuracy study to determine the specificity and sensitivity of currently available ambulatory vital signs monitoring equipment in the detection of hypoxia and the effect of movement on data acquisition. …”
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Psychosocial considerations in pediatric heart transplantation: Initial validation of the Pediatric Psychosocial Assessment Tool at a single center by Michael O. Killian, PhD, MSW, Sonnie E. Mayewski, MSW, Schyler E. Brumm, MSW, Zhe He, PhD, Dipankar Gupta, MBBS, DCH, MD

“…To address this gap, the Pediatric Psychosocial Assessment Tool (PPAT) was developed to provide a structured, semi-quantitative framework for evaluating psychosocial risk in pediatric transplant candidates. Methods: This study presents initial validation data for the PPAT, based on 189 assessments conducted at a large pediatric heart transplant center. …”
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Computer-Aided Intra-Operatory Positioning of an MRgHIFU Applicator Dedicated to Abdominal Thermal Therapy Using Particle Swarm Optimization by Yacine M'Rad, Caecilia Charbonnier, Marcelo Elias de Oliveira, Pauline Coralie Guillemin, Lindsey Alexandra Crowe, Thibaud Koessler, Pierre-Alexandre Poletti, Sana Boudabbous, Alexis Ricoeur, Rares Salomir, Orane Lorton

“…This paper presents a software tool developed to optimize the positioning of a HIFU transducer dedicated to abdominal thermal therapy, to maximize the treatment&#x0027;s efficiency while minimizing the near-field risk. <italic>Methods:</italic> A software tool was developed to determine the theoretical optimal position (TOP) of the transducer based on the minimization of a cost function using the particle swarm optimization (PSO). …”
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Clinical correlation between intestinal flora profiles and the incidence of postmenopausal osteoporosis by Cuifeng Zhu, Yuan Zhang, Yi Pan, Zhentian Zhang, Yan Liu, Xiuping Lin, Jinchuan Cai, Zhuang Xiong, Yong Pan, Hezhongrong Nie

“…Purpose This study aimed to explore the characteristics of intestinal microflora polymorphism in postmenopausal women, and to determine the pathophysiological changes of gene polymorphism of intestinal flora and bone metabolism in postmenopausal osteoporosis (PMOP) patients.Methods A total of 104 postmenopausal women with PMOP or normal bone density were included. …”
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PEI‐PLGA nanoparticles significantly enhanced the immunogenicity of IsdB137‐361 proteins from Staphylococcus aureus by Beiyan Wang, Yazun Dong, Yuwei Cen, Shujie Chen, Xue Wen, Kaiyue Liu, Shuangshuang Wu, Liquan Yu, Yongzhong Yu, Zhanbo Zhu, Jinzhu Ma, Baifen Song, Yudong Cui

“…Because PEI‐PLGA nanoparticles are generated by PEI conjugate with PLGA to develop great potential as a novel immune adjuvant, the immunogenicity of IsdB137‐361 is likely be strengthened by PEI‐PLGA. Methods Here, PEI‐PLGA nanoparticles containing IsdB137‐361 proteins were prepared by optimizing the entrapment efficiency. …”
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Leveraging Big Data for Economic Stability: A Dashboard for ASEAN's Future Growth by Norfiza Ibrahim, Nurul Athirah Aziz, Azmi Abu Seman, Nadia Abdul Wahab, Aznoora Osman, Siti Sarah Md Ilyas

“…The primary goals of this research are to determine the techniques and requirements of an economic stability indicator dashboard for ASEAN countries, to create a console utilizing Big Data methods and to assess the usefulness of this system. …”
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Ethanol consumption during gestation promotes placental alterations in IGF-1 deficient mouse placentas [version 3; peer review: 1 approved, 2 approved with reservations, 1 not appr... by Mario Bermúdez De León, Diego Rodríguez-Mendoza, Carolina Zertuche-Mery, Inma Castilla-Cortázar, Oscar R Fajardo-Ramírez, Fabiola Castorena-Torres, Marcela Galindo-Rangel, Patricio Gómez-Álvarez, Irene Martín-Estal, Andrea Leal López

“…Methods Wild type (WT, Igf1 +/+) and heterozygous (HZ, Igf1 +/-) female mice were given 10% ethanol in water during 14 days as an acclimation period and throughout pregnancy. …”
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Finding order in measuring disorders: Measurement Uncertainty of Thyroid Function Tests at a tertiary care hospital in Eastern India by Asis Bhattacharya, Kasturi Mukherjee, Arkajit Dasgupta, Debi Mallick, Mousumi Mukhopadhyay

“…Thyroid disorders constitute a global health menace but can be efficiently managed if diagnosed early via reliable immunoassays. …”
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Calculation and Experimental Study of the Dynamics of the Track Mover Bypass of a Cross-Country Transport Vehicle by Alexey I. Taratorkin, Sergey V. Abdulov, Viktor B. Derzhanskii, Alexandr A. Volkov, Evgeniy B. Sarach, Alexandr I. Komissarov

“…The article presents an analysis of the methods for studying the dynamics of the branches of the track bypass, substantiates and proposes a research methodology and a simulation spatial model of the track mover of a cross-country transport vehicle, which differs from the common string inertialess and rod inertial models of the branches of the track mover by the ability to take into account a complex set of kinematic and force factors excited during the movement of the tracked vehicle in steady and transient motion modes. …”
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How useful is Nanopore adaptive sampling for sequencing Schistosoma mansoni miracidia? [version 1; peer review: 2 approved] by Andrina Barungi, Moses Arinaitwe, Thomas Crellen, Amy B. Pedersen, Arne Jacobs, Rivka M. Lim, Poppy H.L. Lamberton, Joanne P. Webster, Thomas M. Arme

“…Alternative enrichment strategies will be necessary to improve sequencing efficiency and data quality for S. mansoni WGS.…”
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COTI-2 suppresses the malignancy of bladder cancer by inducing apoptosis via the AMPK-mTOR signaling pathway by Yuancai Zheng, Keqi Wang, Chenyu Wu, Yuying Qin, Yihan Sun, Xinyu Lu, Yupeng Xu, Gonghui Li

“…Moreover, it efficiently suppressed the migration and invasion of BCa cells. …”
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Evaluating spectral indices for water extraction: Limitations and contextual usage recommendations by Chuanwu Zhao, Haishuo Wei, Gudina Legese Feyisa, Thiaggo de Castro Tayer, Gelilan Ma, Hanyi Wu, Yaozhong Pan

“…Currently, various technologies have been applied to water information monitoring, with remote sensing-based spectral index methods being widely used due to their simplicity, low cost, and large-scale observation capabilities. …”
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Longitudinal Assessment of Parkinson’s Motor Symptoms and Dopaminergic Dysfunction Patterns Using DaTSCAN by Amir Hossein Najmi, Armin Ariaei, Mahboobeh Khezri, Masoud Noroozi, Melika Arab Bafrani, Avesta Gheysari, Farideh Sabetghadam, Mehdi Ahmadi, Mohammad Sadeghi, Mahsa Mayeli

“…Introduction: Determining Parkinson’s disease (PD) stage and severity are among the factors affecting treatment strategy. …”
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AI-powered machine learning models for monitoring and optimization of biodrying process by Abhisit Bhatsada, Panida Payomthip, Tanik Itsarathorn, Ye Nyi Nyi Lwin, Eka Wahyanti, Sirintornthep Towprayoon, Suthum Patumsawad, Chart Chiemchaisri, Komsilp Wangyao

“…Among all models tested, deep learning methods demonstrated superior accuracy, with Long Short-Term Memory (LSTM) achieving the highest predictive performance (R² = 0.988 training, R² = 0.987 testing). …”
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Production studies of the disinfectant “Enzidez” by V. Kozhyn, V. Salata, M. Kukhtyn, Y. Horiuk, T. S. Matviishyn

“…The purpose of this study was to determine the effectiveness of the created disinfectant “Enzidez” in the production conditions of veterinary medicine clinics. …”
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Duration of onset, body temperature and C-reactive protein can be used to predict the results of pus culture in children with acute osteomyelitis of long bones by Haiting Jia, Yanan Liu, Tao Liu

“…ROC curve (ROC) was used to evaluate the diagnostic efficiency of culture-negative. Logistic regression analysis was conducted to determine independent risk factors for culture-negative. …”
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Impact of Alarm Frequency on Dialysis Adequacy using Online Clearance Monitor System in Haemodialysis Machine: A Cross-sectional Study by S Swadeeshwaran, P Hemanth, Aksa Shibu

“…However, further research is needed to establish optimal protocols for alarm management that balance treatment efficiency with patient safety.…”
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Glucocorticosteroids and Postradiation Macular Edema: Rationale for Choice of Therapy and Efficacy of Use by I. E. Panova, A. A. Bikhovsky, E. V. Samkovich, E. M. Svistunova

“…Early diagnosis of PMO, as well as the use of intravitreal dexamethasone implant (“Ozurdex”) determines high efficiency of treatment and maximum visual rehabilitation of patients.…”
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Optimal duration of therapy in the recovery period of vestibular diseases by M. V. Zamergrad, V. A. Parfenov, N. N. Yakhno

“…The paper gives the results of an observational program, whose purpose was to determine the optimal duration of vestibular rehabilitation in combination with the use of tanakan in patients with non-progressive unilateral peripheral vestibular disorder.Patients and methods. …”
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The Role of High-Tech Jobs in Regional Development by A. A. Ugryumova, M. V. Savelyeva

“…In the study there have been used methods of analysis and synthesis of information, systematic, logical, comparative and economic analysis, expert assessments. …”
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