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9741
Prilling as an Effective Tool for Manufacturing Submicrometric and Nanometric PLGA Particles for Controlled Drug Delivery to Wounds: Stability and Curcumin Release
Published 2025-01-01“…Curcumin (CCM), a hydrophobic compound classified under BCS (Biopharmaceutics Classification System) class IV, was selected as the model drug. Methods: Key process parameters, including polymer concentration, solvent type, nozzle size, and surfactant levels, were optimized to obtain stable particles with a narrow size distribution determined by DLS analysis. …”
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9742
Assessing the Quality of the Endocervical Component: Pitfalls to Cervical Cancer Screening in Limpopo Province, South Africa
Published 2025-07-01“…Method A mixed-method research approach was used for the study. …”
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9743
Measuring. Monitoring. Management. Control
Published 2024-12-01“…Using the variational optimization method, the optimal type of the specified dependence is calculated. …”
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9744
Integrating KEMIRA with Interval-Valued Neutrosophic Numbers to Assess University English Teaching Quality: A Multi-Attribute Decision-Making Model
Published 2025-04-01“…Key contributions include extending the KEMIRA model to INSs, determining attribute weights using the average method, and applying INN-KEMIRA to complex MADM problems. …”
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9745
Deoxyribonuclease Is a Potential Counter Regulator of Aberrant Neutrophil Extracellular Traps Formation after Major Trauma
Published 2012-01-01“…Methods. Thirty-nine major trauma patients, 14 with and 25 without sepsis development were enrolled in this prospective study. …”
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9746
Research on the Flight Performance of Biomimetic Moth Based on Flapping Function Control
Published 2025-02-01“…The key control parameters are clarified, the control strategy of the flapping-wing aircraft is optimized, and the maneuverability and controllability of the aircraft are improved, providing a theoretical basis and practical support for the development of control methods for biomimetic flapping-wing aircraft.…”
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9747
Mathematical Modeling of Gas-Cleaning Equipment with a Highly Developed Phase Contact Surface
Published 2018-11-01“…The vortex flow of the gas-liquid flow and its pulsating nature of the movement contribute to the intensification of the crushing process and coagulation of the drop gas-liquid flow in the layer of a regular moving nozzle. Methods of mathematical modeling of the process of movement of a polydisperse aerosol in a turbulent gas-liquid flow have been used. …”
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9748
Wall conditions on HL-2A and HL-3 tokamaks
Published 2025-03-01“…The study also evaluated the effectiveness of various methods for removing impurities. Additionally, siliconization on HL-3 was implemented successfully with determination of all key control parameters.…”
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9749
Solar Absorption Air Conditioning Systems Based on Low Temperature Evaporative Air Coolers
Published 2020-06-01“…The results obtained allow us to expand the field of practical use of evaporative cooling methods, for example, to achieve air comfort parameters in the air conditioning system with a developed, more effective than the traditional, circuit design.…”
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9750
Purification and Molecular Characterization of a Mammalian Neurotoxin as a Pharmaceutical Tool from the Venom of Iranian Scorpion Androctonus crassicauda
Published 2025-03-01“…To gain greater insights into the structural and functional impacts of toxins from Androctonus crassicauda (Buthidae), a dangerously venomous scorpion species, its venom was isolated, purified, and characterized. Methods: Long chain toxin with four disulfide bonds purified by size exclusion chromatography and reversed-phase HPLC and characterized by amino acid sequencing and molecular weight determination. …”
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9751
Oxidative phosphorylation in brown adipose tissue in a type II diabetes mellitus mouse model after forced treadmill running
Published 2024-04-01“…To study the effect of forced exercises on the content and parameters of oxidative phosphorylation in brown adipose tissue of mice with type II diabetes mellitus.Materials and methods. To model the disease, we used a high-fat diet and physical exercises in the form of forced treadmill running for 4 weeks. …”
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9752
Silver-hollow mesoporous silica nanoparticles for clarithromycin delivery in an animal model of helicobacter pylori
Published 2025-07-01“…Background: Nanoparticle-based drug delivery systems offer a promising approach to overcoming antimicrobial resistance and enhancing therapeutic efficacy.Objective(s): This study aimed to evaluate the efficacy of silver-hollow mesoporous silica nanoparticles (Ag-HMSNs) in the targeted delivery of clarithromycin for eradicating Helicobacter pylori (H. pylori).Materials and Methods: A synergistic formulation comprising silver nanoparticles and clarithromycin-loaded hollow mesoporous silica nanoparticles (Ag-HMSNs@CLT) was examined for its antibacterial activity against H. pylori. …”
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9753
Circadian Regulator-Mediated Molecular Subtypes Depict the Features of Tumor Microenvironment and Indicate Prognosis in Head and Neck Squamous Cell Carcinoma
Published 2023-01-01“…Herein, the present study set out to explore the significance of circadian regulator genes (CRGs) in HNSCC. Materials and Methods. The molecular landscape and clinical significance of 13 CRGs in HNSCC were explored based on The Cancer Genome Atlas (TCGA). …”
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9754
Improving Bus Operations through Integrated Dynamic Holding Control and Schedule Optimization
Published 2018-01-01“…Results show that the proposed model significantly reduce passengers average travel time compared with existing methods.…”
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9755
Extracellular Volume Derived from Equilibrium CT for the Prediction of Survival Outcomes in Patients with Pancreatic Ductal Adenocarcinoma
Published 2025-04-01“…Methods This retrospective study included 83 patients who underwent CT and R0 resection between January 2016 and September 2023. …”
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9756
STATE POLICY AS A TOOL FOR INCREASING THE INTERNATIONAL COMPETITIVENESS OF THE NATIONAL ECONOMY
Published 2025-06-01“…The methodological basis of the work is a set of general scientific and special research methods, in particular analysis and synthesis, induction and deduction, comparative analysis, and a systemic approach. …”
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9757
Novelty in the treatment of episodic tension-type headache
Published 2010-12-01“…Nonsteroidal anti-inflammatory drugs (NSAIDs) whose efficiency is determined by the rapid and complete regression of cephalgia are primarily used to relieve an ETTH attack. …”
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9758
Understanding what really helps to ensure access to diagnostic services in the Indian Public Health System: a realist synthesis of the Common Review Mission reports (2007-2021)
Published 2023-07-01“…The objective of the study was to understand key health system factors augmenting or limiting access to diagnostic services and outcomes. # Methods Common Review Mission (CRM) reports between 2007 and 2021 were selected for the study. …”
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9759
Pathomorphological changes of the vascular bed and the state of collateral blood flow in cerebral infarction
Published 2020-08-01“…To study the pathomorphological changes of the vascular bed and the state of collateral blood flow in cerebral infarction. Materials and methods. The brains of 45 deceased patients with hemispheric infarctions with different terms of the disease were studied during the work. …”
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9760
The Concession Agreement as a Form of Involving Small Private Companies into the Effective Management of State Property
Published 2017-12-01“…In accordance with the problem defined the purpose of the study is the proposal of measures for effective management of state property. Determined that the licensing system existing in the Russian Federation, have shown their high efficiency in the development of large mineral deposits, but for the development of small man-made deposits it is not effective. …”
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