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METTL16/IGF2BP2 axis enhances malignant progression and DDP resistance through up-regulating COL4A1 by mediating the m6A methylation modification of LAMA4 in hepatocellular carcino...
Published 2025-04-01“…Gene expression levels were detected by quantitative real-time polymerase chain reaction (qRT-PCR), western blot, and immunohistochemistry (IHC). …”
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Application of low-vacuum scanning electron microscopy and energy-dispersive X-ray spectrometry for detection of renal tubular crystals: a case of nephrocalcinosis in the setting o...
Published 2025-07-01“…The extent of renal calcification can range from molecular-level alterations to macroscopic stone formation, contributing to progressive kidney injury. While early detection is critical for prognosis, limited studies have characterized the structural and elemental composition of renal calcifications associated with AN. …”
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Detection of subclinical left ventricular dysfunction by global longitudinal strain imaging in diabetic and prediabetic patients and its correlation with high-sensitivity C-reactiv...
Published 2025-05-01“…Early STE detection may allow interventions to prevent heart failure progression. …”
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Carcinoma Penis Manifesting as Upfront Supraclavicular Lymph Node Metastases Detected by 18F-Fluorodeoxyglucose Positron Emission Tomography Scan: Report of an Extremely Rare and A...
Published 2022-03-01“…Carcinoma penis is a rare malignancy accounting 0.5 to 1% cases in the developed countries with a slightly higher incidence in the developing nations. Slow locoregional progression is characteristic of penile carcinoma and distant metastases are very uncommon. …”
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Carcinoma penis manifesting as upfront supraclavicular lymph node metastases detected by 18F-fluorodeoxyglucose positron emission tomography scan: Report of an extremely rare and a...
Published 2021-10-01“…Carcinoma penis is a rare malignancy accounting 0.5%–1% of cases in the developed countries with a slightly higher incidence in the developing nations. Slow locoregional progression is characteristic of penile carcinoma (PC) and distant metastases are very uncommon. …”
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A smartphone-colorimetric dual-mode diagnosis method for breast cancer detection of BRCA-1 gene base on silver plated substrate and catalytic hairpin assembly amplification
Published 2025-04-01“…In this study, we successfully devised a heterogeneous system based on G-quadruplex DNAzyme for label-free and enzyme-free visual detection of BRCA-1. Moreover, the distinctive G-quadruplex (G4) DNAzyme ensures precise and accurate detection through enzyme-free amplification, colorimetric detection, and catalytic hairpin assembly mechanisms. …”
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Exploring mean kurtosis in MR diffusion kurtosis imaging for early detection of lumbar spine degeneration: a systematic review [version 1; peer review: 2 approved]
Published 2025-04-01“…Results Findings indicate that MK plays a crucial role in detecting microstructural changes in the intervertebral disc space of the lumbar spine. …”
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MyμAlbumin: A Cutting-Edge Immunoturbidity-Based Device with Real-Time and Seamless Data Transmission for Early Detection of Chronic Kidney Disease at the Point of Care
Published 2025-06-01“…Previously, we developed and validated the MyACR point-of-care (PoC) device, which facilitates the monitoring of CKD progression through real-time data transmission, thus enhancing patient management. …”
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A Loop-Mediated Isothermal Amplification Assay Utilizing Hydroxy Naphthol Blue (LAMP-HNB) for the Detection of <i>Treponema pallidum</i> Subspp. <i>pallidum</i>
Published 2024-10-01“…<i>pallidum</i> is a spirochaete bacterium that causes syphilis, one of the most common sexually transmitted diseases. Syphilis progresses through four distinct stages, each characterized by specific symptoms, namely primary, secondary, latent, and late (tertiary) syphilis. …”
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A plasma biomarker panel for detecting early amyloid-β accumulation and its changes in middle-aged cognitively unimpaired individuals at risk for Alzheimer’s diseaseResearch in con...
Published 2025-06-01“…Summary: Background: Plasma biomarkers of Alzheimer’s disease (AD) change during preclinical stages, indicating potential for detecting amyloid-β (Aβ) pathology in cognitively unimpaired (CU) individuals. …”
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Sorting misorganized books in libraries based on ant colony algorithm
Published 2025-12-01“…Its progressiveness is reflected in the fact that the loss rate converges to 0.02 after 300 iterations. …”
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Real-Time Image Analysis for Intelligent Aircraft De-Icing Decision Support Systems
Published 2025-07-01“…Aircraft icing and snow accumulation are significant threats to flight safety and operational efficiency, necessitating rapid and accurate detection methods. The aim of this study was to develop and comparatively evaluate artificial intelligence (AI) models for the real-time detection of ice and snow on aircraft surfaces using vision systems. …”
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Improving Virological Monitoring of HDV Infection: A Proof-of-Concept Comparative Study of Bosphore and AltoStar<sup>®</sup> Assays in Patients Treated with Bulevirtide
Published 2025-06-01“…Hepatitis delta virus (HDV) infection is associated with severe hepatic complications and rapid progression towards liver cirrhosis and hepatocellular carcinoma. …”
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GazeMap: Dual-Pathway CNN Approach for Diagnosing Alzheimer’s Disease from Gaze and Head Movements
Published 2025-06-01“…Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that impairs cognitive function, making early detection crucial for timely intervention. …”
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Liver fatty acid-binding protein point-of-care testing detects heat-induced organ damage: a pilot study in Japanese male self-defense force personnel
Published 2025-02-01“…Recent studies have reported that heat-induced AKI can progress to chronic kidney disease (CKD). We previously reported that urinary levels of liver fatty acid-binding protein (L-FABP) are elevated in patients with severe heat-related illness. …”
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Persistence of power Doppler ultrasonography-detected synovitis over 1 year of follow-up predicts poor prognosis in rheumatoid arthritis in clinical remission: the SONORE prospecti...
Published 2024-09-01“…Objectives (1) To assess the progression of ultrasonography-detected synovitis in a cohort of patients with rheumatoid arthritis (RA) in remission during 1 year of follow-up (2) to evaluate the ability of consecutive examinations of ultrasonography to predict relapse (R) or radiographic progression (RP) at 1 year.Methods Patients with RA (2010 American College of Rheumatology-European Alliance of Associations for Rheumatology criteria) in clinical remission (Disease Activity Score in 28 joints (DAS28)<2.6 without clinically active synovitis) were included. …”
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Detection of sperm DNA damage in male infertility patients and evaluation of Levocarnitine efficacy using sperm chromatin diffusion (SCD) and AI-DFI methods: a cross-sectional stud...
Published 2025-03-01“…The results showed that sperm concentration, progressive motility, viability, and normal morphology rate were significantly lower in the DNA damaged group, and correlation analysis showed that the results of sperm DNA damage detection was negatively correlated with these semen parameters. …”
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