Instant and low-cost detection of urinary microalbumin using smartphone technology and a paper-based platform with a colorimetric ratio analysis by Nutcha Larpant, Chanatnan Tetsiri, Theerasak Rojanarata, Wanida Laiwattanapaisal

“…Abstract Early detection of microalbuminuria is essential for preventing the progression of nephropathy and improving patient management. …”
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A Network Analysis Approach to Detect and Differentiate Usher Syndrome Types Using miRNA Expression Profiles: A Pilot Study by Rama Krishna Thelagathoti, Wesley A. Tom, Chao Jiang, Dinesh S. Chandel, Gary Krzyzanowski, Appolinaire Olou, Rohan M. Fernando

“…It presents in three clinical types—USH1, USH2, and USH3—with varying onset, severity, and disease progression. Existing diagnostics primarily rely on genetic profiling to identify variants in USH genes; however, accurate detection before symptom onset remains a challenge. …”
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Liquid Biopsy Detects Relapse Five Months Earlier than Regular Clinical Follow-Up and Guides Targeted Treatment in Breast Cancer by Fiona Tsui-Fen Cheng, Nina Lapke, Chin-Chu Wu, Yen-Jung Lu, Shu-Jen Chen, Pei-Ning Yu, Yen-Ting Liu, Kien Thiam Tan

“…Four months after treatment initiation, a second ctDNA analysis suggested a relapse, and the patient clinically progressed after five months of everolimus therapy. …”
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A nonparametric approach for detecting urban polycentric spatial structure in China using remote sensing nighttime light and point of interest data by Linlin Jiang, Yizhen Wu, Junru Wang, Huiran Han, Kaifang Shi

“…Differentiated spatiotemporal patterns were found in the evolutionary trajectories of MUPS in China, with a progressive intensification in the degree of spatial decentralization. …”
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Advancing Alzheimer’s disease detection: a novel convolutional neural network based framework leveraging EEG data and segment length analysis by Md Nurul Ahad Tawhid, Siuly Siuly, Enamul Kabir, Yan Li

“…Abstract Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that primarily affects memory, thinking, and behavior, leading to dementia, a severe cognitive decline. …”
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A 6-tsRNA signature for early detection, treatment response monitoring, and prognosis prediction in diffuse large B cell lymphoma by Jun Rao, Lin Xia, Qiong Li, NaYa Ma, Xinlei Li, Jiali Li, Lidan Zhu, Pan Zhao, Yunjing Zeng, Sha Zhou, Huanping Guo, Shijia Lin, Song Dong, Shifeng Lou, Fangyi Fan, Jin Wei, Jiang F. Zhong, Li Gao, Shengwen Calvin Li, Xi Zhang

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Analytical validation of a flow cytometric method for the detection and quantification of canine mast cells in peripheral blood, bone marrow, and lymph node by Giulia Iamone, Fulvio Riondato, Rachel Hanford, Amandine Lejeune, Amir Kol

“…This validation establishes a foundation for future studies on the prognostic implications of mast cell infiltration in MCT progression.…”
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Detection the Genetic Polymorphisms of the Programmed Cell Death Gene PD1.3 G/A (rs11568821) in Coronavirus Disease Patients by Dheyaa Saleh Mahdi, Refif Sabih AL-Shawk, Zainab A. Hamid

“…Both the dominant and recessive models used in the research failed to detect a connection with the risk of COVID-19 severity. …”
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A Radio Frequency Interference Screening Framework—From Quick-Look Detection Using Statistics-Assisted Network to Raw Echo Tracing by Jiayuan Shen, Bing Han, Yang Li, Zongxu Pan, Di Yin, Yugang Feng, Guangzuo Li

“…We take the data of Sentinel-1 terrain observation with progressive scan (TOPS) mode as an example. By combining the statistics-assisted network with the sliding-window algorithm and the error-tolerant training strategy, it is possible to accurately detect and locate RFI in the quick looks of an SLC product. …”
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Comprehensive analysis of faecal metagenomic and serum metabolism revealed the role of gut microbes and related metabolites in detecting colorectal lateral spreading tumours by Hao Lin, Yudai Chen, Ming Zhou, Hongli Wang, Lichun Chen, Li Zheng, Zhixin Wang, Xiaoling Zheng, Shiyun Lu

“…These results suggest that gut microbiota and metabolite alterations in LST contribute to intestinal inflammation and CRC development, underscoring their potential as biomarkers for early detection and therapeutic targets.…”
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Urinary 5-HIAA as a Potential Diagnostic Marker in Acute Appendicitis: A Preliminary Report of Its Promising Role in Early Detection by Murat Demir, Alper Gumus, Huseyin Kilavuz, Feyyaz Gungor, Sibel Yaman, Baki Ekci, Idris Kurtulus

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Targeted Detection of 76 Carnitine Indicators Combined with a Machine Learning Algorithm Based on HPLC-MS/MS in the Diagnosis of Rheumatoid Arthritis by Rui Zhang, Juan Wang, Xiaonan Zhai, Yuanbing Guo, Lei Zhou, Xiaoyan Hao, Liu Yang, Ruiqing Xing, Juanjuan Hu, Jiawei Gao, Fengjuan Wang, Jun Yang, Jiayun Liu

“…Conclusions: Carnitine is integral in the progression of RA. The diagnostic model developed shows excellent diagnostic capacity, improving early detection and enabling timely intervention to minimize disability associated with RA.…”
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A novel fluorescent probe, triphenylamine rhodamine-3-acetic acid (mRA) for the detection of Amyloid-β aggregates in Alzheimer's disease by Raja Chinnappan, Raja Chinnappan, Mateen A. Khan, Taj Mohammad, Sarah Mohammed Allwaibh, Shanmugam Easwaramoorthi, Ahmed Yaqinuddin, Sandhanasamy Devansan, Tanveer Ahmad Mir, Tanveer Ahmad Mir, Imtaiyaz Hassan

“…This study provides a rationale for using mRA as a biosensor for the detection of Aβ aggregates in biological fluids, offering a potential tool for the early diagnosis and monitoring of amyloid progression in AD.…”
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A Novel Hybrid Technique for Detecting and Classifying Hyperspectral Images of Tomato Fungal Diseases Based on Deep Feature Extraction and Manhattan Distance by Guifu Ma, Seyed Mohamad Javidan, Yiannis Ampatzidis, Zhao Zhang

“…Accurate and early detection of plant diseases is essential for effective management and the advancement of sustainable smart agriculture. …”
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Development and evaluation of a CRISPR/Cas12a-based diagnostic test for rapid detection and genotyping of HR-HPV in clinical specimens by Lijuan Yin, Ziqian Zhao, Chunhua Wang, Caihong Zhou, Xiuzhen Wu, Baoxue Gao, Liangyuan Wang, Shuli Man, Xinkuan Cheng, Qiankun Wu, Siqi Hu, Hongxia Fan, Long Ma, Hui Xing, Liang Shen

“…Our platform enables the detection and genotyping of 14 types of HR-HPV by using type-specific crRNAs. …”
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Proposed Comprehensive Methodology Integrated with Explainable Artificial Intelligence for Prediction of Possible Biomarkers in Metabolomics Panel of Plasma Samples for Breast Canc... by Cemil Colak, Fatma Hilal Yagin, Abdulmohsen Algarni, Ali Algarni, Fahaid Al-Hashem, Luca Paolo Ardigò

“…Metabolomics technology is a feasible and comprehensive method for early disease detection and biomarker identification at the molecular level. …”
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In situ monitoring tool of phycotoxins: Research progress of solid phase adsorption toxin tracking (SPATT)(原位藻毒素监测工具：固相吸附毒素跟踪技术研究进展) by 张文广(ZHANG Wenguang), 渠佩佩(QU Peipei), 李冬梅(LI Dongmei), 徐轶肖(XU Yixiao), 周国伟(ZHOU Guowei), 佟蒙蒙(TONG Mengmeng)

“…This paper reviews the key process and application progress of SPATT in marine phycotoxins adsorption, summarizes the physicochemical properties, application scenarios and screening methods of different macroporous resins, describes the preparation method and pretreatment procedure of SPATT resin bags/discs, compares the extraction and analysis methods of phycotoxins adsorbed by different resins and puts forward suggestions in toxin monitoring, sample handling and laboratory detection of SPATT based on the structural characteristics of toxins and practical experience, aiming to provide reference for SPATT application in phycotoxins monitoring and safety warning of aquatic products.固相吸附毒素跟踪（solid phase adsorption toxin tracking，SPATT）技术利用合成大孔树脂模拟滤食贝类的摄食过程，实现对藻毒素的原位被动吸附。…”
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The correlation between the level of 25-hydroxyvitamin D [25(OH)D] and residency of multiple sclerosis patients in Montenegro – higher levels only in men in the north of the countr... by Vujisić Slavica, Vodopić Sanja, Idrizović Zilha, Radulović Ljiljana

“…Serum levels of 25(OH)D were associated with disability and progression in MS patients. Lower levels of 25(OH)D were detected in female patients from the North. …”
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Experience in the use of olaparib poly (ADP-ribose) polymerase inhibitors in maintenance therapy of BRCA-associated ovarian cancer by V. N. Zhurman, V. M. Nechushkina

“…Mutations in the BRCA1/2 genes were detected in 98 out of 355 (27.6 %) patients. Mutations of the BRCA1+ gene were detected in 62 out of 230 patients with ovarian cancer of stages IIIC–IV (27.0 %), the BRCA2 gene – in 9 out of 230 (3.9 %). …”
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Navigated transcranial magnetic stimulation possibilities in difficult diagnostic cases upper motor neuron lesions – case report by I. S. Bakulin, A. V. Chervyakov, M. N. Zakharova, N. A. Suponeva, M. A. Piradov

“…Absence of the pyramidal syndrome does not allow diagnosing ALS, and the diagnosis of progressive muscular atrophy should be set in these cases. …”
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