Earlier Diagnosis of Progressive Disease during Bevacizumab Treatment Using O-(2-F-Fluorethyl)-L-Tyrosine Positron Emission Tomography in Comparison with Magnetic Resonance Imaging by Norbert Galldiks, Marion Rapp, Gabriele Stoffels, Veronika Dunkl, Michael Sabel, Karl-Josef Langen

“…Positron emission tomography using the radiolabeled amino acid O-(2-[ 18 F]fluoroethyl)-L-tyrosine ( 18 F-FET-PET) may help detect the metabolically active tumor extent. We present 18 F-FET-PET imaging findings in a glioblastoma patient during bevacizumab treatment suggesting an earlier diagnosis of tumor progression than magnetic resonance imaging changes, which are based on the RANO criteria.…”
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Exosomal lncRNA H19 promotes the progression of hepatocellular carcinoma treated with Propofol via miR‐520a‐3p/LIMK1 axis by Dongmei Wang, Na Xing, Tao Yang, Junqi Liu, Huaping Zhao, Juan He, Yanqiu Ai, Jianjun Yang

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A Matter of Time: Delayed Presentation and Rapid Progression from Gonadotropin-Independent to Gonadotropin-Dependent Precocious Puberty following Successful Treatment for a Leydig... by C. R. Naotunna, D. N. Siriwardana, B. C. Lakmini, M. Samarasinghe, N. Atapattu

“…Occasionally, it has been reported few children are progressed to gonadotropin-dependent precocious puberty (GDPP) after initial clinical and biochemical recovery. …”
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Local anesthetic ropivacaine inhibits non-small cell lung cancer progression by modulating the hsa_circ_0001320/miR-518a-5p axis by LiQun Cheng, RongRong Shen, Zhen Ma, Yuan Guo, Yi Peng

“…Abstract Objective This study investigated the possible mechanisms by which ropivacaine influences the progression of non-small cell lung cancer (NSCLC). Methods Plasmid vectors or oligonucleotides interfering with circ_0001320 or miR-518a-5p were transfected into ropivacaine-treated NSCLC cells, and circ_0001320 and miR-518a-5p levels were detected by RT-qPCR. …”
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circHIPK2 promotes malignant progression of laryngeal squamous cell carcinoma through the miR-889-3p/MCTS1/IL-6 axis by Yang-Guang Sun, Zhen-Kun Yu, Xi Chen, Si-Yao Zhang, Wan-Juan Wu, Kai Liu, Lei Cheng

“…Mechanistic studies showed that circHIPK2 competitively bound to miR-889–3p, elevated MCTS1 level, promoted IL-6 secretion, and ultimately accelerated the malignant progression of LSCC. In conclusion, an axis involving circHIPK2, miR-889–3p, MCTS1 and IL-6 regulates the malignant progression of LSCC. circHIPK2 expression may serve as a novel diagnostic and prognostic biomarker for LSCC.…”
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m6A Methylation Regulator RBM15-Mediated Upregulation of ITGBL1 mRNA Stability Aggravates Colon Adenocarcinoma Progression by Remodeling the Tumor Microenvironment by Jie Zhu, Dengliang Liu, Yingying Zou

“…We aimed to investigate the function of RBM15 in COAD progression and its underlying molecular mechanism. …”
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Serum Irisin, Myostatin, and Myonectin Correlate with Metabolic Health Markers, Liver Disease Progression, and Blood Pressure in Patients with Metabolic Dysfunction-Associated Fatt... by Anna F. Sheptulina, Elvira M. Mamutova, Anastasia Yu. Elkina, Yuriy S. Timofeev, Victoria A. Metelskaya, Anton R. Kiselev, Oxana M. Drapkina

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Predicting Tumour Progression of ID-8 Syngeneic Mouse Ovarian Cancer with Blood Biomarkers of CA-125, IL-6 and VEGF: A Prospective Laboratory-Based Study by Kenny Chitcholtan, Arron Dyer, Peter Sykes

“…However, limited information associated with disease progression is obtained from such studies; whether it is the best model to study advanced ovarian cancer phenotype or suitable preclinical biomarkers for detecting and monitoring ovarian cancer progression is under study. …”
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HGH1 Promotes Breast Cancer Progression Through the PI3K/AKT/NF-κB Signaling Pathway: Potential Role for Prognosis and Targeted Therapy by Hu W, Si D, Liu C, Tie D, Xu D, Li N

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Osteopontin derived from hypoxia-induced M2 macrophages promotes osteosarcoma progression through modulation of EGR3/ISG15 signaling and RIG-I expression by Chunyang Xing, Wei Hu, Liyuan Zhao

“…This study aimed to explore the role and mechanism of hypoxic-induced M2 macrophages in promoting the progression of OS. Methods Differentially expressed proteins in hypoxic macrophage supernatants were detected by antibody array. …”
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Characterization of the genomic landscape of canine diffuse large B-cell lymphoma reveals recurrent H3K27M mutations linked to progression-free survival by Anna Darlene van der Heiden, Raphaela Pensch, Sophie Agger, Heather L. Gardner, William Hendricks, Victoria Zismann, Shukmei Wong, Natalia Briones, Bryce Turner, Karin Forsberg-Nilsson, Cheryl London, Kerstin Lindblad-Toh, Maja Louise Arendt

“…Finally, a survival analysis revealed that H3K27M mutations in H3C8 were associated with increased hazard ratios for progression-free survival. No copy number aberrations were associated with survival. …”
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Let-7a-5p derived from parathyroid hormone (1–34)-preconditioned BMSCs exosomes delays the progression of osteoarthritis by promoting chondrocyte proliferation and migration by Litao Shao, Lu Ding, Weizhao Li, Chi Zhang, Yu Xia, Miaoyu Zeng, Zhizhong Ye, David Y. B. Deng

“…For in vivo experiments, let-7a-5p delays the progression of OA. Conclusion Our study shows that ExoPTH may improve the regulatory inflammatory responses to delays the progression of OA by shuttling let-7a-5p. …”
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A novel mechanism of FTO modulating the progression of endometriosis through mediating the m6A methylation of GEF-H1 in a YTHDF1-dependent manner by Xin-Yu Ding, Hua-Ying Zhang, Jia-Hao Chen, Meng-Jie Yang, Zhi-Xiong Huang, Yi-Hong Lei, Qin-Kun Sun, Jian-Bin Bai, Dian-Chao Lin, Jian-Fa Lan, Lu-Lu Ren, Zheng-Yi Chen, Wei-Dong Zhou, Qiong-Hua Chen

“…Our findings suggest potential therapeutic avenues for targeting FTO to alleviate EMs progression.…”
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Crack Detection in Civil Infrastructure Using Autonomous Robotic Systems: A Synergistic Review of Platforms, Cognition, and Autonomous Action by Rong Dai, Rui Wang, Chang Shu, Jianming Li, Zhe Wei

“…This study focuses on robotic crack detection and proposes a structured framework that connects three core modules: the physical platform (robots and sensors), the cognitive core (crack detection algorithms), and autonomous action (navigation and planning). …”
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The use of a two-tiered testing strategy for the simultaneous detection of small EGFR mutations and EGFR amplification in lung cancer. by Marzena Anna Lewandowska, Karol Czubak, Katarzyna Klonowska, Wojciech Jozwicki, Janusz Kowalewski, Piotr Kozlowski

“…Therefore, the reliable detection of mutations is critical for the application of appropriate therapy. …”
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Optic Disc and Optic Cup Segmentation for Glaucoma Detection from Blur Retinal Images Using Improved Mask-RCNN by Tahira Nazir, Aun Irtaza, Valery Starovoitov

“…Glaucoma is a fatal eye disease that harms the optic disc (OD) and optic cup (OC) and results into blindness in progressed phases. Because of slow progress, the disease exhibits a small number of symptoms in the initial stages, therefore causing the disease identification to be a complicated task. …”
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Detection and Prediction of Wind and Solar Photovoltaic Power Ramp Events Based on Data-Driven Methods: A Critical Review by Jie Zhang, Xinchun Zhu, Yigong Xie, Guo Chen, Shuangquan Liu

“…The integration of artificial intelligence has accelerated progress in both event prediction and error correction. …”
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Detection of Flexible Pavement Surface Cracks in Coastal Regions Using Deep Learning and 2D/3D Images by Carlos Sanchez, Feng Wang, Yongsheng Bai, Haitao Gong

“…Developments in artificial intelligence and machine learning (AI/ML) can aid in the progress of more robust and precise detection algorithms. …”
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DAViT: A Domain-Adapted Vision Transformer for Automated Pneumonia Detection and Explanation Using Chest X-Ray Images by Michael Fu, Chakkrit Tantithamthavorn, Trung Le

“…Pneumonia, a leading cause of mortality worldwide, especially among children under five, is typically diagnosed via chest X-rays. However, detecting it is challenging as expert radiologists must discern subtle patterns. …”
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A deep learning approach for heart disease detection using a modified multiclass attention mechanism with BiLSTM by Umesh Kumar Lilhore, Sarita Simaiya, Monish Khan, Roobaea Alroobaea, Abdullah M. Baqasah, Majed Alsafyani, Afnan Alhazmi

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