Leveraging ResNet50 With Swin Attention for Accurate Detection of OCT Biomarkers Using Fundus Images by S. Tamilselvi, M. Suchetha, Rajiv Raman

“…The duration of diabetes in patients affects both the prevalence and incidence of macular edema, as well as the progression of retinopathy. Therefore, regular screening of diabetes patients for the early detection of retinal abnormalities is essential to prevent the development and progression of DR and DME. …”
Get full text

The detection of erosive changes in the joints of hands and feet in rheumatoid arthritis: a comparison of ultrasound and radiology methods by Olga G. Alekseeva, Alexander V. Smirnov, Svetlana I. Glukhova, Maria V. Severinova, Evgeny L. Nasonov, Alexander V. Volkov

“…CONCLUSION: Ultrasound examination and radiography are not equivalent methods of detecting erosions in rheumatoid arthritis, however, ultrasound examination helps detecting early progression of the process, which is a key to successful therapy of rheumatoid arthritis.…”
Get full text

Risk factors and approaches for detection of Trichomonas tenax, the silent culprit in periodontal disease: A narrative review by Nurin Jazlina Nor Azmi, Suharni Mohamad, Wan Nazatul Shima Shahidan, Haslina Taib, Zeehaida Mohamed, Emelia Osman

“…Results: This review highlights the incidence of T. tenax with periodontal diseases, the risk factors that contribute to the infection of T. tenax and available detection methods for the identification of the protozoan. …”
Get full text

An Outlier Detection Approach to Recognize the Sources of a Process Failure within a Multivariate Poisson Process by Chia-Ding Hou, Rung-Hung Su

“…An out-of-control multivariate Poisson process can be detected using an alarm on a multivariate control chart. …”
Get full text

Recent Research Advancements of Coffee Quality Detection: Targeted Analyses vs. Nontargeted Fingerprinting and Related Issues by Yumei Chen, Boyan Gao, Weiying Lu

“…This review introduced case studies of the current research progresses on targeted and nontargeted detection approaches. …”
Get full text

MRI detection of senescent cells in porcine knee joints with a β-galactosidase responsive Gd-chelate by Kerem Nernekli, Dilyana B. Mangarova, Vidyani Suryadevara, Mohammadjavad Hajipour, Jian-Hong Tang, Jie Wang, Tie Liang, Marek Harris, Tsuyoshi Ueyama, Jennifer K. Lyons, Michael E. Moseley, Raheleh Roudi, Laura Pisani, Ricarda von Krüchten, Ramesh Duwa, Sarah Ying Lu-Liang, Zahra Shokri Varniab, Iryna Vasyliv, Neeladrisingha Das, Masatoshi Murayama, Issei Shinohara, Guillem Pratx, Stuart B. Goodman, Thomas J. Meade, Heike E. Daldrup-Link

“…Abstract Senescent cells promote osteoarthritis progression through the secretion of inflammatory mediators. …”
Get full text

Exosomal PD-L1 detection in cancer predictive biomarker for response to immune checkpoint blockade therapy by Tetsuichi Kansha, Tetsuichi Kansha, Tetsuichi Kansha, Xiaojuan Ma, Xiaojuan Ma, Xiaojuan Ma, Hao Wang, Hao Wang, Hao Wang, Xiaotong Yu, Xiaotong Yu, Xiaotong Yu, Ying Song, Ying Song, Ying Song, Zhengyang Guo, Zhengyang Guo, Zhengyang Guo, Jiagui Song, Jiagui Song, Jiagui Song, Lixiang Xue, Lixiang Xue, Lixiang Xue, Lixiang Xue, Jianling Yang, Jianling Yang, Jianling Yang

“…We highlight its potential as a non-invasive biomarker for predicting therapeutic response and monitoring disease progression. Compared with tissue-based PD-L1 assessment, exosomal PD-L1 offers advantages in accessibility and dynamic reflection of tumor immune status. …”
Get full text

Detection of Diabetic Retinopathy Using a Multi-Decision Inception-ResNet-Blended Hybrid Model by Santosh Kumar Henge, Nikhil Reddy Viraati, Musaed Alhussein, Ajay Shriram Kushwaha, Khursheed Aurangzeb, Ravleen Singh

“…Early diagnosis is crucial for reducing and preventing the progression of this condition. However, detecting DR’s early stages remains challenging due to subtle symptoms that are difficult to recognize independently. …”
Get full text

Microfluidic Systems in Cancer Diagnosis: Advancing Exosome and CTC Detection From Laboratory Research to Clinical Application by Bahareh Valinezhad Saghezi, Kamran Mansouri, Rahman Hallaj

“…Microfluidic‐based approaches have the potential to improve early cancer detection and personalized treatment strategies by efficiently collecting and isolating CTCs and extracellular vesicles (EVs), which provide critical information about cancer progression and the response to treatment. …”
Get full text

Ocular Coherence Tomography Unveils Alport Syndrome: A Critical Tool in Detecting Collagen IV Nephropathies by Abdelrahman Ibrahim, Zena Altawallbeh, Monica Patricia Revelo, Martin Gregory, Laith Al-Rabadi

Get full text

Design and Application of a Radiofrequency Spectrophotometry Sensor for Measuring Esophageal Liquid Flow to Detect Gastroesophageal Reflux by Pedro J. Fito, Ricardo J. Colom, Rafael Gadea-Girones, Jose M. Monzo, Angel Tebar-Ruiz, F. Javier Puertas, Marta Castro-Giraldez

“…This study presents a radiofrequency spectrophotometry sensor specifically designed to detect esophageal liquid flow and ionicity in real time without disrupting the patient’s daily life. …”
Get full text

5-Hydroxymethylcytosine modifications in circulating cell-free DNA: frontiers of cancer detection, monitoring, and prognostic evaluation by Danjun Song, Zhou Zhang, Jiaping Zheng, Wei Zhang, Jiabin Cai

“…Genetic and epigenetic alterations in circulating cell-free DNA (cfDNA) have emerged as transformative tools for advancing early cancer detection, monitoring, and improving patient outcomes. …”
Get full text

Machine learning-assisted early detection of keratoconus: a comparative analysis of corneal topography and biomechanical data by Arkadiusz Syta, Arkadiusz Podkowiński, Tomasz Chorągiewicz, Robert Karpiński, Jakub Gęca, Dominika Wróbel-Dudzińska, Katarzyna E Jonak, Dariusz Głuchowski, Marcin Maciejewski, Robert Rejdak, Kamil Jonak

“…Abstract Keratoconus is a progressive eye disease characterized by the thinning and bulging of the cornea, leading to visual impairment. …”
Get full text

Optical coherence tomography: new opportunities for detecting preclinical vision disorders in patients with HIV infection and tuberculosis by E. V. Sabadash, S. N. Skornyakov, I. D. Medvinskiy, S. Yu. Krasnoborova, E. A. Burylova, E. V. Telitsina

“…OCT allows early preclinical diagnosis of eye disorders (in the absence of eye complaints) in patients with tuberculosis, including those with concurrent HIV infection. Detection of choroid disorders and AVC changes in such patients allows timely prescription of therapy and prevention of pathological changes from progression.…”
Get full text

An Improved Deep Learning Unsupervised Approach for MRI Tissue Segmentation for Alzheimer’s Disease Detection by Karan Kumar, Isha Suwalka, Adaora Uche-Ezennia, Celestine Iwendi, Cresantus N. Biamba

Get full text

High-Sensitivity Flow Cytometry for the Reliable Detection of Measurable Residual Disease in Hematological Malignancies in Clinical Laboratories by María Beatriz Álvarez Flores, María Sopeña Corvinos, Raquel Guillén Santos, Fernando Cava Valenciano

“…Background: Monitoring of measurable residual disease (MRD) requires highly sensitive flow cytometry protocols to provide an accurate prediction of shorter progression-free survival. High assay sensitivity generally requires rapid processing to avoid cell loss from small bone marrow sample volumes, but this requirement conflicts with the need in most clinical cytometry laboratories for long processing and acquisition times, especially when multiple MRD studies coincide on the same day. …”
Get full text

A labeled medical records corpus for the timely detection of rare diseases using machine learning approaches by Matias Rolando, Victor Raggio, Hugo Naya, Lucia Spangenberg, Leticia Cagnina

“…Most of them affect children, are chronic and progressive, and have no specific treatment. RD patients face diagnostic challenges, with an average diagnosis time of 5 years, multiple specialist visits, and invasive procedures. …”
Get full text

Microbiota as diagnostic biomarkers: advancing early cancer detection and personalized therapeutic approaches through microbiome profiling by Majid Eslami, Ramtin Naderian, Aisa Bahar, Ali Babaeizad, Solaleh Rezanavaz Gheshlagh, Valentyn Oksenych, Hamed Tahmasebi

“…Important microbial signatures, including Bacteroides fragilis and Fusobacterium nucleatum, have been linked to the development and progression of cancer, providing important information on the processes behind carcinogenesis. …”
Get full text

The Statistical Detecting of Sulfur Hexafluoride and Nitrous Oxide Effect on Seasonal Rainfalls in Iran During Recent Decade by Yosef Ghavidel Rahimi, Maysam Tolabi Nejad, Manochehr Farajzadeh

Get full text

Repression of varicella zoster virus gene expression during quiescent infection in the absence of detectable histone deposition. by Jiayi Wang, Nadine Brückner, Simon Weissmann, Thomas Günther, Shuyong Zhu, Carolin Vogt, Guorong Sun, Rongrong Guo, Renzo Bruno, Birgit Ritter, Lars Steinbrück, Benedikt B Kaufer, Daniel P Depledge, Adam Grundhoff, Abel Viejo-Borbolla

“…The only transcripts detected in infected human trigeminal ganglia (TG) obtained shortly after death correspond to the VZV latency-associated transcript (VLT) and associated VLT-ORF63 splice variants. …”
Get full text