Long non-coding RNA CCAT1/miR-218/ZFX axis modulates the progression of laryngeal squamous cell cancer by Yaming Zhang, Haili Hu

“…This study was designed to elucidate the function and mechanisms of colon cancer–associated transcript-1 in the progression of human laryngeal squamous cell cancer. …”
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Upregulation of GSTP1 mediated by chimeric TFE3 promotes TFE3-tRCC progression by targeting JNK signaling pathway by Weixu Chen, Mengtong Wu, Lin Du, Changhua Fang, Hao Wang, Wendi Wang, Chengwei Zhang, Hongqian Guo, Gutian Zhang

“…Furthermore, GSTP1 was found to drive TFE3-tRCC progression via modulation of the JNK signaling pathway. …”
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Expression of variant isoforms of the tyrosine kinase SYK differentially regulates cervical cancer progression through PI3K/AKT pathway by Bingjie Lin, Qixin Wang, Xin Wang, Hongjian Wei, Xiaojing Nie, Li Li, Yonghua Shi

“…The results suggest that SYK(L) and SYK(S) are involved in the progression of cervical cancer through PI3K/AKT signaling pathway, and may serve as potential targets for clinical treatment of advanced cervical cancer.…”
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High immunocompetence in chronic hepatitis patients with normal alanine transaminase levels and and negative hepatitis B e‐antigen for the progression of liver fibrosis by Bianqiao Cheng, Dandan Wu, Ming Zhang, Shiming Chen, Xunyuan Wu, Jingjing Zhong, Meimei Wu, Miaomiao Huo

“…The levels of CD4+, CD4+CD25+, CD8+, and CD4+CD25+CD127LOW regulatory T cells (Tregs) in the patients were detected using flow cytometry; the liver stiffness measurement (LSM) values of the patients were detected using Fibroscan. …”
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FOXK2 regulates fatty acid metabolism and promotes cervical cancer progression by activating the mTOR/DRP1 signaling axis by Dan Liao, Saitian Zeng, Cuifen Li, Yuhong Yao, Min Guo, Yejia Cui, Haohai Huang

“…Lipid metabolism plays a crucial role in providing sufficient metabolites and energy for the rapid proliferation and progression of tumors, significantly influencing the advancement of cervical cancer. …”
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Early diagnosis of progressive multifocal leukoencephalopathy in untreated HIV infection via ultrasensitive PCR testing for JC virus: A case report by Kenji Nakano, Akira Kawashima, Takato Nakamoto, Kazuo Nakamichi, Ryo Kuwata, Seitaro Abe, Eri Inoue, Naokatsu Ando, Haruka Uemura, Daisuke Mizushima, Takahiro Aoki, Katsuji Teruya, Hiroyuki Gatanaga

“…Progressive multifocal leukoencephalopathy (PML) is a fatal demyelinating disease triggered by the reactivation of JC virus (JCV) in individuals with immunodeficiency, particularly those with untreated human immunodeficiency virus (HIV) infection. …”
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KU60019 inhibits ovarian cancer progression by targeting DGAT1/has-miR-1273g-3p axis. by Zhanchuan Ma, Rongjing Dang, Guodong Wu

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Estimated Disease Progression Trajectory of White Matter Disruption in Unilateral Temporal Lobe Epilepsy: A Data-Driven Machine Learning Approach by Daichi Sone, Noriko Sato, Yoko Shigemoto, Iman Beheshti, Yukio Kimura, Hiroshi Matsuda

“…We used the Subtype and Stage Inference (SuStaIn) program to detect the progression trajectory of FA changes and investigated its association with clinical parameters including onset age, disease duration, drug-responsiveness, and the number of anti-seizure medications (ASMs). …”
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Small nucleolar RNA SNORD13H suppresses tumor progression via FBL-dependent 2′-O-methylation in hepatocellular carcinoma by Minglu Zhang, Minglu Zhang, Minglu Zhang, Minglu Zhang, Jianbo He, Jianbo He, Jianbo He, Jianbo He, Rao Fu, Rao Fu, Rao Fu, Rao Fu, Guojian Bao, Guojian Bao, Guojian Bao, Yijun Lu, Yijun Lu, Yijun Lu, Zechuan Zhang, Zechuan Zhang, Zechuan Zhang, Jiawu Yan, Jiawu Yan, Jiawu Yan, Jialu Ding, Jialu Ding, Jialu Ding, Fei Yang, Fei Yang, Fei Yang, Fei Yang, Beicheng Sun, Beicheng Sun, Beicheng Sun, Beicheng Sun

“…The diminution of SNORD13H activates the RAS pathway, contributing to the progression of HCC.DiscussionOur study establishes SNORD13H as a dual-function regulator in HCC progression. …”
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Oxidative Phosphorylation-Related Signature Participates in Cancer Development, and PTPRG Overexpression Suppresses the Cancer Progression in Clear Cell Renal Cell Carcinoma by Liang Huang, Yu Xie, Weiqing Han, Shusuan Jiang, Lingfeng Zeng

“…We believe this study discovered a novel mechanism of ccRCC pathological progression and will provide promising targets for therapeutic strategy development.…”
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OGT-induced O-GlcNAcylation of NEK7 protein aggravates osteoarthritis progression by enhancing NEK7/NLRP3 axis by Chunlei He, Qiang Wu, Zhaogan Zeng, Yadong Yang, Huabin He, Meiyu Hu, Sheng Liu

“…The effects of OGT knockout on OA progression were detected through Safranin O staining, immunohistochemical staining and OARSI score evaluation. …”
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CAFs-released exosomal CREB1 promotes cell progression and immune evasion in thyroid cancer via the positive regulation of CCL20 by Chen Zheng, Hu Hei, Yifei Zhai, Wenbo Gong, Runfang Zhang, Songtao Zhang

“…Exosomal CREB1 knockdown receded cell progression and enhanced CD8+ T function by mediating CCL20. …”
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KAT5 Inhibitor NU9056 Suppresses Anaplastic Thyroid Carcinoma Progression through c-Myc/miR-202 Pathway by Wenjing Xu, Liwei Xie, Yingying Yang, Jiayu Xu, Shang Cai, Ye Tian

“…Knockdown of miR-202 suppressed ATC cell progression, while forced expression of miR-202 partially blocked the inhibitory effect of NU9056 on ATC cells. …”
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CSF3 promotes colorectal cancer progression by activating p65/NF-κB signaling pathway and inducing an immunosuppressive microenvironment by Junfeng Xu, Na Li, Hui Xie, Changwei Duan, Xingchen Liao, Ruoran Li, Heng Zhang, Yuanming Pan, Xianzong Ma, Shuwen Du, Jianqiu Sheng, Xin Wang, Lang Yang, Peng Jin

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Next-generation sequencing of CCR5, CXCR4, and IFNAR1 variants in relation to HIV-1 disease progression and ART response by Kubra Cigdem Pekkoc-Uyanik, Zeynep Gizem Todurga-Seven, Andleeb Shahzadi, Haktan Sonmez, Sevcan Mercan, Bilgul Mete, Fehmi Tabak

“…Our results demonstrate that intronic variations in the IFNAR1 rs2856973:T > A and CXCR4 rs2680880:A > T genes can contribute to modifications in HIV progression and CD4 + T recovery under ART.…”
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hsa_circRNA_092488 Exacerbates the Progression of Deep Vein Thrombosis Through the NLRP3/NF-κB Signaling Pathway by Jian Wang, Binghui Du

“…The proliferation, migration, cell cycle progression, and apoptosis of transfected cells were measured by CCK-8 assay, transwell assay, and flow cytometry. …”
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RETRACTED: Silencing circular RNA VANGL1 inhibits progression of bladder cancer by regulating miR‐1184/IGFBP2 axis by Dengke Yang, Haining Qian, Zhen Fang, An Xu, Shutian Zhao, Bingyan Liu, Dong Li

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Identification and validation of a lenvatinib resistance-related prognostic signature in HCC, in which PFKFB4 contributes to tumor progression and lenvatinib resistance by Jinfeng Wang, Jianfei Shi, Lili Mi, Ning Li, Xin Han, Man Zhao, Xiaoling Duan, Guangjie Han, Jiaojiao Hou, Fei Yin

“…PFKFB4 promotes tumor progression and lenvatinib resistance, highlighting its potential as a novel therapeutic target for HCC. …”
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Systemic immune inflammation index and systemic inflammation response index predict frailty progression in older patients undergoing elective orthopedic surgery by Guanghan Gao, Zitian Zheng, Fei Wang, Yaonan Zhang, Lei Shi, Lin Wang, Hongyu Wang, Qingyun Xue

“…LASSO regression was used to identify important predictive variables, and multivariate logistic regression was employed to assess the associations between SII/SIRI and frailty progression. Restricted cubic splines (RCS) were used to detect potential non-linear relationships between them. …”
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Association between non-insulin-based insulin resistance indicators and frailty progression: a national cohort study and mendelian randomization analysis by Hui Tian, Yong-meng Li, Cheng-qiang Wang, Guo-qiang Chen, Ying Lian

“…Conclusions The non-insulin-based IR indicators, including TyG index, METS-IR and eGDR, were independently associated with the frailty progression and physical function decline. Monitoring and managing abnormal glucose metabolism should be recommended as a part of comprehensive strategies to prevent or delay the progression of frailty.…”
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