LncRNA NORAD promotes the progression of myocardial infarction by targeting the miR-22-3p/PTEN axis by Li Chunxia, Zhang Lihui, Bu Xingpeng, Chu Guofang, Zhao Xiaofang, Liu Yaru

“…Taken together, our study reveals that NORAD promotes the progression of AMI by regulating the miR-22-3p/PTEN axis, and the AKT/mTOR signaling may also be involved in the regulatory processes.…”
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KLF13 promotes esophageal cancer progression and regulates triacylglyceride and free fatty acid metabolism through GPIHBP1 by Pengjie Yang, Benben Zhu, Hongwei Cui, Yongjun Yu, Qin Yu, Linghui Kong, Mengfei Sun, Yuan Liu, Bateer Han, Shuchen Chen

“…Abstract Kruppel-Like Factor 13 (KLF13) has strong effects on cancer occurrence and progression. Nevertheless, the role of KLF13 in oesophagal cancer (EC) remain elusive. …”
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Hsa_circFOXP1 Contributes to Breast Cancer Progression through Regulating miR-338-3p by Kaiding Wu, Kunkun Cheng

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Hsa_circ_0001859 promotes NSCLC progression through the miRNA-101-3p/MMP1 axis by Jianxin Tan, Zhenyu Fan, Rongguo Lu, Shugao Ye

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Low rates of radiographic progression of structural joint damage over 2 years of baricitinib treatment in patients with rheumatoid arthritis by Désirée van der Heijde, Yoshiya Tanaka, Paul Emery, Li Xie, Michael Schiff, Gabriella Meszaros, Taeko Ishii, Marta Casillas, Robert A Ortmann

“…Linear extrapolation was used for missing data.Results Of 2573 randomised patients, 2125 (82.6%) entered the LTE, of whom 1893 (89.1%) entered this analysis. At year 2, progression was significantly lower with initial baricitinib (monotherapy or combination therapy) versus initial MTX in DMARD-naïve patients (proportion with non-progression defined by ≤smallest detectable change (SDC): 87.3% baricitinib 4 mg+MTX; 70.6% MTX; p≤ 0.001). …”
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ROLE OF TRANSFORMING GROWTH FACTOR RECEPTOR B I TYPE (TGF-BRI) IN THE PROGRESSION OF THE LUMINAL BREAST CANCER SUBTYPE by N. N. Babyshkina, S. V. Vtorushin, T. A. Dronova, N. V. Krakhmal, M. V. Zavyalova, M. M. Tsyganov, S. V. Patalyak, E. M. Slonimskaya, N. V. Cherdyntseva

“…The aim of the study was to examine the relationship between the protein and receptor gene expression of transforming growth factor β type I (TGF-βRI) and its polymorphism with progression of luminal breast cancer patients treated by adjuvant tamoxifen. …”
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MicroRNA-18b-5p Inhibits the Malignant Progression of Prostate Cancer Through Downregulating TRAF5 by Wang X, Yu X, Wang Y, Lian J, Li Z, Dong C, Song H, Zhang L, Zhang H, Wang Y

“…Overexpression of TRAF5 abolished the suppressive effects of restored miR-18b-5p on PCa cell progression.Conclusion: This study elucidates that upregulated miR-18b-5p impedes PCa cell progression via downregulating TRAF5, which may provide a novel therapeutic basis for PCa. …”
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Dermatopontin promotes abdominal aortic aneurysm progression via the IL-1β-COL1A1 axis by YIN Huarun, ZHAO Ning, WU Zhiyuan, LI Yongjun, YIN Hongchao

“…Objective To investigate the expression of dermatopontin (DPT) in abdominal aortic aneurysm (AAA) and to explore the mechanism in promoting AAA progression. Methods Differential gene expression (DEG) and GO-KEGG pathway enrichment were used to assess DPT expression level and related pathways in AAA. …”
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The KDM5A/HOXA5 axis regulates osteosarcoma progression via activating the Wnt/β-catenin pathway by Yi Luo, Youzhi He, Yuxia Xu, Yongfu Wang, Li Yang

“…Abstract As an oncogenic driver, lysine-specific demethylase 5A (KDM5A) participates in regulating numerous tumor progression-related processes. Moreover, KDM5A functions as a histone demethylase, modulating the expression levels of its target genes by adjusting methylation levels. …”
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Heat shock transcription factor 1 facilitates liver cancer progression by driving super‐enhancer‐mediated transcription of MYCN by Yizhe Liu, Qili Shi, Yue Su, Zhiao Chen, Xianghuo He

“…Moreover, increased MYCN expression was detected in HCC tumors and correlated with unfavorable patient outcomes. …”
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The m6A writer KIAA1429 regulates photoaging progression via MFAP4-dependent collagen synthesis by Yuanyuan Liu, Jian Li, Chenhui Wang, Jiangbo Li, Kai Luo, Kang Tao, Yuan Tian, Xiang Song, Zhifang Zhai, Yuandong Tao, Jia You, Lihua Wu, Wenqian Li, Yuanyuan Jiao, Rongya Yang, Mingwang Zhang

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Incomplete Thermal Ablation-Induced FOXP4-Mediated Promotion of Malignant Progression in Liver Cancer via NDST2 by Wan W, Pan Y, Pang J, Bai X, Li L, Kang T, Chen J, Wen R, Wen D, Yang H, He Y

“…In the heat-stressed HCC cell model, downregulating FOXP4 inhibited cancer cell progression. Besides, there was a positive association between FOXP4 and NDST2 in liver cancer. …”
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COP1 drives renal cell carcinoma progression by targeting ACSL4 for ubiquitin-mediated degradation and inhibiting ferroptosis by Yuxiao Zheng, Lei Jiang, Feng Qi, Bo Peng

“…BackgroundRenal cell carcinoma (RCC) progression is closely linked to dysregulation of the ubiquitin-proteasome system, particularly aberrant ubiquitination processes governing protein degradation and cell cycle control. …”
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Clinical values of serum interleukin-17A and interleukin-23 in predicting the occurrence and progression of IgA vasculitis nephritis by Peng Li, Wang Li, Liu Wei-jia, Pan Chun-qin, Liu Jie

“…ObjectiveTo explore the clinical values of serum interleukin 17A （IL-17A） and IL-23 in predicting the occurrence and progression of immunoglobulin A vasculitis （IgAV） complicated with nephritis.MethodsFrom January 2018 to October 2021， 71 IgAV patients were selected along with 50 age/gender-matched healthy volunteers as normal control group. …”
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YY1 induced USP13 transcriptional activation drives the malignant progression of hepatocellular carcinoma by deubiquitinating WWP1 by Qingwei Zhu, Zibo Yuan, Qiang Huo, Qiliang Lu, Qingsong Wu, Junwei Guo, Wen Fu, Ying Lu, Lei Zhong, Wenzhong Shang, Di Cui, Shuangshuang Li, Xin Liu, Kangsheng Tu, Dongsheng Huang, Qiuran Xu, Xiaoge Hu

“…Cell Counting Kit-8, colony formation, wound healing, Transwell, and sphere formation assays were used to detect the malignant behaviors of HCC cells in vitro. …”
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A MULTICENTRE STUDY OF ASSESSING THE EFFECTIVENESS OF SALVAGING LYMPHADENECTOMY IN PATIENTS WITH PROSTATE CANCER WITH DISEASE PROGRESSION AFTER THE RADICAL TREATMENT by B. Y. Alekseev, K. M. Nyushko, S. A. Reva, A. K. Nosov, D. G. Prokhorov, T. T. Andabekov, А. А. Krasheninnikov, E. Y. Safronova, А. S. Kalpinskiy, M. А. Gusniev, A. D. Kaprin

“…However, a significant number of patients relapse marker may be associated with the so-called oligo-metastatic disease progression, in which the number of detected metastatic lesions is minimal. …”
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A controlled transfer entropy approach to detect asymmetric interactions in heterogeneous systems by Rishita Das, Maurizio Porfiri

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Nighttime traffic object detection via adaptively integrating event and frame domains by Yu Jiang, Yuehang Wang, Minghao Zhao, Yongji Zhang, Hong Qi

“…Motivated by this progress, we propose an adaptive selection and fusion detection method that leverages both event and RGB frame domains to optimize nighttime traffic object detection jointly. …”
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State of the art detection methods of microplastics as marine litter: a mini review by Rajib Biswas

“…In recent years, significant progress has been made in developing detection methods to enhance our understanding of microplastic pollution. …”
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Parameter Optimisation of Support Vector Machine using Genetic Algorithm for Cyberbullying Detection by Mohd Qorib Alqowiy, Ema Utami

“…Several social media platforms enable users to connect with one another easily. However, this progress often comes with negative impacts. One such impact is cyberbullying, which has become a growing concern. …”
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