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621
Whole-Brain Atrophy Rate in Idiopathic Parkinson’s Disease, Multiple System Atrophy, and Progressive Supranuclear Palsy
Published 2016-01-01“…In PSP, the use of a-WBAR required one-half of the patients needed for clinical scales to detect a 50% reduction in their progression. In MSA, one-quarter of the patients would be needed to detect the same effect. a-WBAR is a reasonable candidate to consider as a surrogate endpoint in short clinical trials using smaller sample sizes. …”
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622
A Review of Fault Detecting Devices for Belt Conveyor Idlers
Published 2024-03-01“…The shift towards automated inspection methods represents considerable progress in conveyor system maintenance, enhancing safety and efficiency while posing challenges in data analysis and implementation costs. …”
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623
Advance in Application of Deep Learning in Food Quality and Safety Detection
Published 2025-03-01“…This paper focuses on the application progress of deep learning in food quality and safety detection. …”
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624
Improving change detection performance with generative-adversarial augmentation of dataset
Published 2024-11-01“…The main source of information used for maps updating is remote sensing, and the progress in sensors and methods of data analysis allows automatically retrieving the changes in observed scene from multi-time image series. …”
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625
Pathogenesis of progressive scarring trachoma in Ethiopia and Tanzania and its implications for disease control: two cohort studies.
Published 2015-05-01“…<h4>Conclusions/significance</h4>Scarring progressed in the absence of detectable C. trachomatis, which raises uncertainty about the primary drivers of late-stage trachoma. …”
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626
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627
Concentration of vitamin D metabolite – 25(OH)D3 as a predictor of breast cancer progression
Published 2023-01-01“…Additional criteria were developed allowing to predict BC progression.Conclusion. In order to detect secondary changes (distant metastases in ВС patients) and improve patient monitoring, it is recommended to use additional diagnostic methods and determine the intermediate metabolite of vitamin D – 25(OH)D3 in peripheral blood.…”
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628
Rapidly Progressive Bilateral Leg Weakness in a 65-Year-Old Man: A Case Report
Published 2025-03-01“…We describe the case of a 65-year-old previously healthy crane operator who presented to the emergency department due to symmetrical, gradually progressive gait instability and leg weakness. Due to evidence of a pulmonary mass in combination with polyneuroradiculopathy, a thoracoscopic upper lobe resection was performed with histological findings of an adenocarcinoma. …”
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629
Ovarian Carcinoma and Serous Effusions. Changing Views Regarding Tumor Progression and Review of Current Literature1
Published 2001-01-01“…In addition, tumor progression in ovarian carcinoma and the biological characteristics of carcinoma cells in effusions compared to their counterparts in solid tumors are poorly understood. …”
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630
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631
miR-370-3p affects the progression of postmenopausal osteoporosis through targeting INO80
Published 2025-07-01“…In addition, miR-370-3p targeted INO80 and affected the disease progression of PMO. Conclusions miR-370-3p/INO80 may serve as a promising biomarker for both the diagnosis and therapeutic management of PMO.…”
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632
THE INFLUENCE OF INSULIN RESISTANCE ON THE FORMATION AND PROGRESSION OF METABOLIC SYNDROME COMPONENTS (THE RESULTS OF A FIVE-YEAR STUDY)
Published 2015-09-01“…To study the effect of insulin resistance on the formation and progression of metabolic syndrome components on the basis of a 5-year follow-up.Material and methods. …”
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633
MiR-135a-3p inhibits the progression of prostate cancer by targeting TLR4
Published 2025-12-01“…It exerts an inhibitory effect on the progression of prostate cancer by targeting TLR4.…”
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634
Evaluation of Study and Patient Characteristics of Clinical Studies in Primary Progressive Multiple Sclerosis: A Systematic Review.
Published 2015-01-01“…In addition, the endpoints specified could not detect progression adequately.<h4>Conclusion</h4>Optimal PPMS study methods involve appropriate patient selection, especially regarding the PPMS phenotype and progression rate. …”
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635
Contributions of Pathobiological and Translational Science to Understanding and Managing Ischemic Heart Disease: Progress, Impediments, and Future Directions
Published 2025-07-01“…Nevertheless, opportunities for further progress against ischemic heart disease have come from new perspectives and approaches, including (1) recognition that functionally significant ischemic heart disease can result from microvascular dysfunction or epicardial coronary atherosclerosis; (2) rapid diagnosis of AMI subtypes through application of the Universal Definition of Myocardial Infarction based on high-sensitivity cardiac troponin measurements; (3) the Canadian Cardiovascular Society classification of AMI based on stages of tissue injury severity, as detected by advanced imaging; (4) implementation of the occlusion vs nonocclusion MI paradigm to prompt aggressive management of all ST-segment elevation MI and the one-third of non–ST-segment elevation MI with total occlusion; and (5) implementation of the Early Heart Attack Care program, which emphasizes prodromal symptom recognition to prevent AMI progression.…”
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636
WYC-209 inhibited GC malignant progression by down-regulating WNT4 through RARα
Published 2024-12-01“…More importantly, WNT4 overexpression breached the inhibitory effect of WYC-209 on GC progression. Mechanically, WYC-209 significantly promoted the binding between retinoic acid receptor α (RARα) and WNT4 promoter. …”
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637
Analysis of treatment efficacy, tolerability, and survival of patients receiving antifibrotic therapy for progressive nonidiopathic pulmonary fibrosis
“…BACKGROUND: There are still disagreements about diagnostic criteria and treatment of progressive pulmonary fibrosis (PPF). Real-life data and survival analyses have a guiding role in clarifying this issue. …”
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638
Ultrasound <i>vs.</i> x-ray: a new way for clinicians to track scoliosis progression?
Published 2025-02-01“…Although only four patients exhibited true progression (≥5° increase in Cobb angle), changes in scoliotic angles were effectively detected using ultrasound. …”
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639
Unsupervised machine learning identifies biomarkers of disease progression in post-kala-azar dermal leishmaniasis in Sudan.
Published 2025-03-01“…Our results indicate that the combination of anaemia and a weak Th1 immunological response is likely the main physiological mechanism that leads to progressive PKDL.<h4>Conclusions</h4>A combination of 14 biochemical variables identified by unsupervised ML was able to detect a worsening PKDL state in Sudanese patients. …”
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640
LINC01094 targets miR-1266-5p to halt neoplasm progression of cervical cancer
Published 2025-12-01“…Overexpression of LINC01094 targeting miR-1266-5p prevents the progression of CC neoplasm.…”
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