Progressive Familial Intrahepatic Cholestasis: A Descriptive Study in a Tertiary Care Center by Fahad I. Alsohaibani, Musthafa C. Peedikayil, Abdulaziz F. Alfadley, Mohamed K. Aboueissa, Faisal A. Abaalkhail, Saleh A. Alqahtani

“…Background. Progressive familial intrahepatic cholestasis (PFIC) is a rare genetic disorder that results from defective mechanisms of bile secretion. …”
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Gene Expression Differences in Peripheral Blood of Parkinson's Disease Patients with Distinct Progression Profiles. by Raquel Pinho, Leonor C Guedes, Lilach Soreq, Patrícia P Lobo, Tiago Mestre, Miguel Coelho, Mário M Rosa, Nilza Gonçalves, Pauline Wales, Tiago Mendes, Ellen Gerhardt, Christiane Fahlbusch, Vincenzo Bonifati, Michael Bonin, Gabriel Miltenberger-Miltényi, Fran Borovecki, Hermona Soreq, Joaquim J Ferreira, Tiago F Outeiro

“…Altogether, our study provides preliminary evidence that expression changes in specific groups of genes and pathways, detected in peripheral blood samples, may be correlated with differential PD progression. …”
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Logopenic and nonfluent variants of primary progressive aphasia are differentiated by acoustic measures of speech production. by Kirrie J Ballard, Sharon Savage, Cristian E Leyton, Adam P Vogel, Michael Hornberger, John R Hodges

“…Differentiation of logopenic (lvPPA) and nonfluent/agrammatic (nfvPPA) variants of Primary Progressive Aphasia is important yet remains challenging since it hinges on expert based evaluation of speech and language production. …”
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Long Noncoding RNA SAMMSON Promotes Melanoma Progression by Inhibiting FOXA2 Expression by Lijuan Yang, Meiling Zhou, Shulei Wang, Xiaojia Yi, Guohang Xiong, Jing Cheng, Buqing Sai, Qiao Zhang, Zhe Yang, Yingmin Kuang, Yuechun Zhu

“…Taken together, our data indicate that SAMMSON plays an important role in melanoma progression and can be a valuable biomarker and therapeutic target in melanoma.…”
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The signaling function of IDO1 incites the malignant progression of mouse B16 melanoma by E Orecchini, ML Belladonna, MT Pallotta, C Volpi, L Zizi, E Panfili, M Gargaro, F Fallarino, S Rossini, C Suvieri, A Macchiarulo, S Bicciato, G Mondanelli, C Orabona

“…Faster growth and malignant progression of B16H350A cells, also detectable in vivo, were found to be accompanied by a reduction in tumor-infiltrating CD8+ T cells and an increase in Foxp3+ regulatory T cells. …”
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Modulation of fibroblast behavior by Leishmania: a pathway to understanding disease progression in cutaneous leishmaniasis by Tarcisio Navegante de Queiroz Filho, Brenda Furtado Costa, Ana Paula Drummond Rodrigues

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LINC00601 promotes the progression of glioma via the p-STAT3 signaling pathway by Chao Ma, Linqi Wang, Renwu Zhang, Tong Li, Peng Li, Yuxiang Ding, Dejun Wu, Yinyan Wang

“…Conclusions LINC00601, which facilitates glioma progression by modulating the p-STAT3 signaling pathway, could serve as a potential molecular target for glioma therapy.…”
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GTPBP2 in-frame deletion in canine model with non-syndromic progressive retinal atrophy by Leonardo Murgiano, Jessica K Niggel, Eylem Emek Akyürek, Roberta Sacchetto, Gustavo D. Aguirre

“…Abstract Progressive retinal atrophy (PRA), caused by aberrant functioning of rod/cone photoreceptors, leads to blindness affecting mammals, including dogs. …”
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Mass spectrometric profiling reveals association of -glycan patterns with epithelial ovarian cancer progression by Huanhuan Chen, Zaian Deng, Chuncui Huang, Hongmei Wu, Xia Zhao, Yan Li

“…However, changes in patterns of N -glycans in tumor tissues during epithelial ovarian cancer progression have remained largely undefined. To investigate whether changes in N -glycan patterns correlate with oncogenesis and progression of epithelial ovarian cancer, we profiled N -glycans from formalin-fixed paraffin-embedded tissue slides using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and quantitatively compared among different pathological grades of epithelial ovarian cancer and healthy controls. …”
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SLC25A19 drives colorectal cancer progression by regulating p53 by Jinbo Jiang, Xuemei Li, Jiayong Wang, Shaofei Chen, Lingjuan Chen

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Multi-Global Navigation Satellite System for Earth Observation: Recent Developments and New Progress by Shuanggen Jin, Xuyang Meng, Gino Dardanelli, Yunlong Zhu

“…The Global Navigation Satellite System (GNSS) has made important progress in Earth observation and applications. With the successful design of the BeiDou Navigation Satellite System (BDS), four global navigation satellite systems are available worldwide, together with Galileo, GLONASS, and GPS. …”
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Latest progress and prospect of NRP-1 targeted molecular probes for breast cancer diagnosis by CAI Shuyue, XIE Quan, ZHOU Yuxuan, LIU Qingzhu, QIU Ling, LIN Jianguo

“…The expression and distribution of NRP-1 in breast cancer can be detected by nuclear medicine, optical imaging and multimodal imaging methods in a non-invasive, real-time and accurate manner, which has significant application value in the early diagnosis, staging, treatment, and prognosis evaluation of breast cancer. …”
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Silencing FGL1 promotes prostate cancer cell apoptosis and inhibits EMT progression by Shuaizhi Zhu, Zengshun Kou, Chengcheng Xiao, Lu Wang, Jiaxi Zhu, Yu Zheng, Hai Zhu

“…Silencing FGL1 promotes prostate cancer cell apoptosis and inhibits EMT progression. FGL1 may be an independent prognostic marker and therapeutic target in PCa.…”
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SQLE promotes osteosarcoma progression via activating TGFβ/SMAD signaling pathway by Qi Song, Lina He, Jing Feng

“…The present study aims to investigate the role of SQLE in the progression of OS and explore the potential mechanisms. …”
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Whole-Genome Sequencing Reveals the Progress of Genetic Breeding in <i>Eriocheir sinensis</i> by Xuanpeng Wang, Gaowei Zhang, Dandan Gao, Yongchun Ge, Yongxu Cheng, Xinhai Wang

“…The present study evaluated the recent progress of the genetic improvement of <i>E. sinensis</i> by our research group, providing valuable evidence for further genetic improvement in this species. …”
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Validation of Novel Biomarkers for Prostate Cancer Progression by the Combination of Bioinformatics, Clinical and Functional Studies. by Saeid Alinezhad, Riina-Minna Väänänen, Jesse Mattsson, Yifeng Li, Terhi Tallgrén, Natalia Tong Ochoa, Anders Bjartell, Malin Åkerfelt, Pekka Taimen, Peter J Boström, Kim Pettersson, Matthias Nees

“…However, only few predictive markers identified in silico have also been validated for clinical, functional or mechanistic relevance in disease progression. In this study, we have used a broad, bioinformatics-based approach to identify such biomarkers across a spectrum of progression stages, including normal and tumor-adjacent, premalignant, primary and late stage lesions. …”
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Unraveling progressive verbal memory deficits in Huntington’s disease: insights from the LASSI-L by Luis A. Sierra, Japleen Kaur, Samuel A. Frank, Samuel A. Frank, Mark A. Halko, Mark A. Halko, Rosie E. Curiel Cid, David A. Loewenstein, Jody Corey-Bloom, Simon Laganiere, Simon Laganiere

“…Furthermore, 88% of participants adhered to the full sequential decline pattern, progressing from deficits in PSI, to frPSI, and then to RSI.DiscussionThe LASSI-L appears to be a useful tool for detecting early and progressive cognitive changes in Huntington’s disease, particularly by capturing the sequential nature of verbal memory deficits, including early vulnerability to interference. …”
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Influence of Personal Respiratory and Visual Protective Equipment on the Development and Progression of Dry Eye Syndrome by A. V. Kuroyedov, P. Ch. Zavadski, A. Yu. Brezhnev, V. V. Gorodnichii, I. R. Gazizova, A. V. Seleznev, O. N. Onufriichuk, Yu. I. Razhko, Z. M. Nagornova

“…To study the influence of personal protective equipment (PPE) of the respiratory and visual systems on the development and progression of dry eye syndrome (DES) and its relationship with other risk factors for medical workers.Patients and methods. …”
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Urinary GADD45G Protein Excretion Is Associated with IgA Nephropathy Progression by Min-Jeong Lee, Hyunee Yim, Ji Eun Park, Inwhee Park, Heungsoo Kim, Gyu-Tae Shin

“…<b>Conclusions</b>: Urinary GADD45G excretion was significantly associated with kidney disease progression in patients with IgA nephropathy.…”
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PROGRESSION OF CAROTID ARTERY ATHEROSCLEROSIS DURING TREATMENT TO TARGET IN PATIENTS WITH EARLY RHEUMATOID ARTHRITIS by E. V. Udachkina, D. S. Novikova, T. V. Popkova, I. G. Kirillova, E. I. Markelova, Yu. N. Gorbunova, D. E. Karateev, E. L. Luchikhina, N. V. Demidova, M. A. Borisova, G. V. Lukina, S. I. Glukhova, A. V. Volkov

“…HDL-Cmean and CRPmean are independent risk factors for progression of CAA.…”
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